The invention provides antibacterial gauze as well as a preparation method and application thereof, and belongs to the technical field of gauze. The antibacterial gauze comprises two
layers of gauze and fibers distributed between the two
layers of gauze; the
fiber comprises a
fiber tube and a filler filled in the
fiber tube; the fiber tube comprises a first degradable
polymer; the filler comprises a second degradable
polymer and an
antibacterial agent. The antibacterial gauze provided by the invention comprises the fibers, the fibers comprise the fiber tubes and the filler filled in the fiber tubes, the filler contains the antibacterial
medicine, and when the antibacterial gauze is used for binding up a wound, polymers in the fiber tubes and the filler are gradually degraded, so that the antibacterial
medicine in the filler is gradually released, and the
antibacterial effect is improved. Therefore, the antibacterial time of the gauze is prolonged. The result of the embodiment shows that the
release time of the antibacterial
medicine in the filler in the antibacterial gauze provided by the invention reaches 28 days, and the antibacterial gauze has a long-term
antibacterial effect.