Novel medical disinfection and sterilization ultrasonic coupling agent

Abstract

The invention provides a novel medical disinfection and sterilization ultrasonic coupling agent. According to the coupling agent, disinfection and sterilization active ingredients, which are extracted from medicinal and dietary plants, are adopted, magnolol is used as a major ingredient for rapid disinfection and sterilization, and syringic acid, anisic acid, dipotassium glycyrrhizinate and vanillin are used as synergistic action ingredients. Through a compound prescription, the efficiency of disinfection and sterilization is improved when conducting ultrasonic detection and the like, and cytotoxicity, skin irritation and sensitization of a medical ultrasonic coupling agent are reduced; each piece of the coupling agent disclosed by the invention is applied to each person each time, so that such problems as cross infection and the like in clinical examination by virtue of ultrasonic instrument are avoided; meanwhile, effects on protecting mucosa skin, moistening the skin and the like can be achieved; and moreover, the medical ultrasonic coupling agent, which is applicable to complete skin, incomplete skin and mucosa, has an important significance. In addition, the novel medical disinfection and sterilization ultrasonic coupling agent disclosed by the invention is simple in preparation method and production process, low in cost and convenient for popularization and industrial production.

Description

technical field [0001] The invention relates to a medical disinfection and sterilization ultrasonic coupling agent, in particular to a disinfection and sterilization ultrasonic coupling agent used for ultrasonic detection of intact skin, incomplete skin and cavity mucosa. Background technique [0002] When using an ultrasonic instrument for diagnosis and inspection, in order to fill the tiny gap between the ultrasonic probe and the skin surface, it is necessary to use a product with a small sound wave attenuation coefficient, sound speed and sound impedance similar to human tissue, excellent acoustic performance, and a neutral pH value. Toxic, non-irritating, non-sensitizing, and good biocompatibility, the medical ultrasonic coupling agent enables the sound waves to enter the body smoothly to obtain reliable images or achieve therapeutic tissue. The medical ultrasonic couplant has no corrosion or damage to the ultrasonic probe, and is easy to erase, has good thixotropy and d...

AI Technical Summary

Problems solved by technology

[0003] Most of the medical ultrasonic coupling agents currently on the market are mainly formulated with carbomer, sodium hydroxymethylcellulose, alginate, propylene glycol, sodium hydroxide, water, etc. The matrix of these coupling agents does not have Antibacterial function, prone to cross-infection; in addition, a small number of bactericidal ultrasonic coupling agents use bactericides with some chemical components, such as: a B-ultrasonic ultrasonic coupling agent and its preparation method (application number: 02110128.0) uses polymer Viton iodine, a medical ultrasonic coupling agent with disinfection and sterilization functions and its preparation method (application number: 200710078112.9) used 2,4,4-trichloro-2-hydroxydiphenyl ether, a disinfection and sterilization type medical ultrasonic coupling agent and Its preparation method (application number: 200810026888.0) uses one of polyhexamethylene biguanide, benzalkonium chloride, benzalkonium bromide, and chlorhexidine acetate. These bactericidal ingredients are often not biodegradable and do not have good Biocompatibility, most patients cannot immediately wash off the ultrasonic coupling agent attached to the skin or mucous membrane with water after ultrasonic diagnosis, which directly leads to the residue of these bactericidal ingredients in the diagnosed part, which has certain skin irritation and has A small amount of components can also enter tissues or even blood through the skin or mucous membranes, causing cytotoxicity

Especially when applied to incomplete skin, the impact is greater, causing harm to the patient's body

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