35 results about "M-anisic acid" patented technology

This invention relates to a composition that is mild to the skin containing a cosmetically acceptable oil; water; a cosmetically acceptable emulsifier having an HLB of from about 1 to about 25; and a preservative comprising an organic acid selected from the group consisting of benzoic acid, p-anisic acid, sorbic acid, lactic acid, acetic acid, formic acid, oxalic acid, tartaric acid, salicylic acid and citric acid; wherein said composition has a pH less than 5 and a buffer capacity of between about 0.001 and about 0.039.

Taste of a non-nutritive steviol glycoside sweetener is improved by using anisic acid in an amount sufficient to mask the metallic aftertaste of the non-nutritive steviol glycoside sweetener when the sweetener is contained in a beverage, beverage concentrate or syrup, or reduced calorie sweetener.

The invention relates to a feed mildew-removal agent used for solving the mildew problem of a feed. The mildew-removal agent used for livestock comprises the following ingredients by weight: 0.5-2.0 parts of cinnamaldehyde, 0.5-3.0 parts of dried orange peel, 0.5-2.0 parts of clove, 0.5-2.0 parts of litsea cubeba, 0.5-2.0 parts of lindera glauca, 0.3-1.0 parts of anisic acid, 0.5-2.0 parts of artemisia capillaries, 0.5-2.0 parts of tarragon, 0.5-3.0 parts of sweet wormwood, 0.5-2.0 parts of wild chrysanthemum flower, 0.5-4.0 parts of rehmanniae radix, 0.5-2.0 parts of ligustrum lucidum, 0.5-2.0 parts of gynura bicolor, 1.0-5.0 parts of semen plantaginis, 0.3-1.0 parts of honeysuckle flower, 1.0-5.0 parts of dandelion, 0.5-2.0 parts of Chinese angelica, 1.0-5.0 parts of sheareria nana, 1.0-5.0 parts of rheum officinale and 2.0-20.0 parts of montmorillonite. The feed mildew-removal agent contains abundant Chinese herbal medicines and trace elements, which can supplement the requirement of the growth of the livestock, promote the growth of the livestock and increase the immunity of the livestock. The feed mildew-removal agent has good adsorptivity and disinfection performance to mildew and can effectively reduce the opportunity of mildew in the livestock, thereby the incidence of disease for livestock due to feed can be reduced, and the feed mildew-removal agent is very suitable for modern breeding industry.

Compositions containing one or more derivatives of essential oil compounds for use in personal care compositions, such as compositions for oral, throat and skin care are disclosed. These derivatives include acetals of parent essential oil aldehydes and ketones; esters or ethers of parent essential oil alcohols and phenolics; and esters of parent essential oil acids. Examples of parent essential oil aldehydes and ketones include citral, cinnamic aldehyde, anisaldehyde, vanillin, ethyl vanillin, heliotropin, carvone, and menthone. Examples of parent essential oil alcohols and phenolics include thymol, eugenol, isoeugenol, dihydroeugenol, carvacrol, carveol, geraniol, nerol, vanillyl alcohol, heliotropyl alcohol, anisyl alcohol, cinnamyl alcohol and ss-ionol. Examples of parent essential oil acids include anisic acid, cinnamic acid, vanillic acid and geranic acid.; The present compositions comprising essential oil derivatives are useful as base flavor or base perfume for incorporation into personal care products and to provide other benefits including antimicrobial efficacy. Optionally the compositions will contain additional antimicrobially- or anti-inflammatory-effective components including those also derived from plant essential oils or synthetic versions thereof.

A novel bacteriostatic agent without corrosion-preventing concept comprises the following components in percentage by mass: 10 to 20 percent of p-hydroxyacetophenone, 20 to 40 percent of pentanediol, 30 to 50 percent of hexanediol, 5 to 15 percent of anisic acid and 5 to 15 percent of leuconostoc / radish root fermentation product filtrate. The bacteriostatic agent is convenient to add, high in compatibility, high in water solubility and insusceptible to separation by crystallization at a low temperature, and has little influence on the system; the smell is extremely low, the transparency is high, the product is insusceptible to color change, and the use experience of users is improved; the bacteriostatic agent does not contain preservative, has a good bacteriostatic effect, effectively reduce irradiation and influence on skin by cosmetics, has low probability of causing skin discomfort, is mild and non-irritant, and is suitable for all kinds of people.

The invention relates to the field of cosmetics, and provides a novel preservative composition and a preparation method and an application thereof, which solve the problems that the existing preservatives mostly use chemical synthetic products as main components, and easily cause irritation to human skin or eyes after used in cosmetics, or the cost is too high. The composition is prepared from thefollowing components by mass percentage: 8 to 15 wt% of levulinic acid, 2 to 7 wt% of anisic acid, 1 to 5 wt% of gluconolactone, 10 to 20 wt% of glycine, 5 to 12 wt% of arginine, and the balance of water. The components of the composition have high safety, are mild and non-irritating, and have the effects of skin conditioning; the five components in the composition synergistically enhance antiseptic properties, have broad-spectrum antibacterial and bactericidal effects, and can completely replace a traditional preservative, which is superior to a conventional no-addition preservative solutionon the market; the composition is directly added to a water phase when used in cosmetics production, which is easy to operate, has good stability, and has no risk of discoloration and odor.

The invention provides a novel medical disinfection and sterilization ultrasonic coupling agent. According to the coupling agent, disinfection and sterilization active ingredients, which are extracted from medicinal and dietary plants, are adopted, magnolol is used as a major ingredient for rapid disinfection and sterilization, and syringic acid, anisic acid, dipotassium glycyrrhizinate and vanillin are used as synergistic action ingredients. Through a compound prescription, the efficiency of disinfection and sterilization is improved when conducting ultrasonic detection and the like, and cytotoxicity, skin irritation and sensitization of a medical ultrasonic coupling agent are reduced; each piece of the coupling agent disclosed by the invention is applied to each person each time, so that such problems as cross infection and the like in clinical examination by virtue of ultrasonic instrument are avoided; meanwhile, effects on protecting mucosa skin, moistening the skin and the like can be achieved; and moreover, the medical ultrasonic coupling agent, which is applicable to complete skin, incomplete skin and mucosa, has an important significance. In addition, the novel medical disinfection and sterilization ultrasonic coupling agent disclosed by the invention is simple in preparation method and production process, low in cost and convenient for popularization and industrial production.

This invention relates to formulations containing a combination of anisic acid, or a salt thereof, or an ester thereof, and a C6-14 fatty acid monoglyceride and to the use of such combinations as a preservative system.

The invention discloses a preparation method of anisic acid, which comprises the following steps: taking a right amount of crude sulfate turpentine, and fractionating to obtain crush anethole; carrying out crystallizing separation on the anethole to obtain the high-purity anethole; adding the high-purity anethole and a NaHSO3 solution into a reaction kettle, and introducing ozone to perform oxidation for 110 minutes, thereby obtaining an anisic aldehyde sodium sulfite addition product A; simultaneously and slowly adding a sodium hydroxide solution and oxydol into A, stirring to react for 5.0-9.0 hours while keeping at 65-85 DEG C to obtain a reaction product B; and after the reaction is finished, adding a HCl solution into B to regulate the pH value to 1-3, and filtering to obtain the anisic acid. The method has the advantages of high yield and high purity and does not use any organic solvent in the separation process, so the product has no toxic or harmful solvent residue and can be used in the industries of medicine, food and cosmetics; the method has the characteristics of mild reaction conditions, simple purification and refinement and high product purity, and is simple to operate; and by using the ozone and oxydol as oxidizers, the reaction product is water, so the oxidizers are green and environment-friendly.

The present invention relates to a skin preparation composition for external use having excellent antiseptic ability without using chemical antiseptics. More particularly, the present invention relates to a skin preparation composition for external use, comprising: glyceryl undecylenate having excellent antiseptic ability; and one or more mixtures of ethylhexylglycerin, glyceryl caprylate, p-anisic acid and a citrus mixed extract, thus improving antiseptic ability through the increased effects of antiseptic abilities of those materials.

Taste of a non-nutritive steviol glycoside sweetener is improved by using anisic acid in an amount sufficient to mask the metallic aftertaste of the non-nutritive steviol glycoside sweetener when the sweetener is contained in a beverage, beverage concentrate or syrup, or reduced calorie sweetener.

A pharmaceutical composition for anti-viral cancer treatment in mammals, comprising a therapeutically effective amount of Anisomelic acid or salts thereof. The pharmaceutical composition may comprise Anisomelic acid or salt thereof in an oil-in-water emulsion, for example in an isotropic mixture of at least one oil and at least one surfactant or, alternatively, in a hydrophilic solvent and a co-solvents or surfactant or a combination thereof. A method of treating or preventing of cancer in a mammal, wherein the p53 pathway is deregulated by viral oncoproteins, is also provided.

The invention discloses a bacterial strain for generating anisic acid by converting anethole, and a screening method and application of the bacterial strain. The bacterial strain BurkholderiaspWGB31 which is high in yield of anisic acid can be obtained by the following steps of: enriching by using enrichment mediums with different anethole concentration gradients in soil of anise forest, inoculating to a 5g / l anethole screening culture medium, performing plate screening, transferring to a seed culture medium, performing shake-flask culture at the temperature of 28 DEG C for 12 hours, transferring to a fermentation culture medium, performing shake-flask culture at the temperature of 28 DEG C for 48 hours, and determining the content of anisic acid by a gas chromatographic method. The production rate of anisic acid obtained by optimizing the fermentation condition is 28.75 percent.

According to the present invention, there is provided a cosmetic composition comprising a cosmetically acceptable carrier and a preservative system, wherein the preservative system comprises (i) an antimicrobial agent; (ii) a chelating agent comprising ethylenediamine tetraacetic acid (EDTA) or a derivative thereof; and (iii) an antimicrobial booster agent selected from the group consisting of ethylhexylglycerin, caprylyl glycol, hydroxy acetophenone, caprylhydroxamic acid, phenethyl alcohol, p -anisic acid, glyceryl caprylate, levulinic acid, sodium levulinate, propanediol, hexanediol, pentylene glycol, capryloyl glycine, methylpropanediol, phenylpropanol, sodium anisate, and combinations thereof, and the antimicrobial agent is present in an amount of from about 0.001% to about 1% by weight of the composition.

The invention discloses a method for preparing a mosquito repellent by using a star anise oil extracted waste solution. The method comprises the following steps: firstly, extracting a mixture of anisic aldehyde, anisic ketone and anisic acid from the star anise oil extracted waste solution; secondly, mixing 30 to 50 parts of the mixture of the anisic aldehyde, the anisic ketone and the anisic acid, 10 to 20 parts of glycerol, 1 to 5 parts of eucalyptus robusta smith leaf oil, 2 to 20 parts of propylene glycol, 3 to 5 parts of polyoxyethylene sorbitan monooleate, 1 to 3 parts of sorbitan monopalmitate, 20 to 40 parts of folium eucalypti citriodorae hydrolat and 0.5 to 1 part of pyrrolidone-5-sodium carboxylate according to the mass ratio at the temperature of 75 DEG C and emulsifying to obtain the mosquito repellent. The method is simple to operate; the prepared product can effectively prevent mosquitoes, and is environmentally-friendly, low in cost and convenient to popularize and use.

This invention relates to a composition that is mild to the skin containing a cosmetically acceptable oil; water; a cosmetically acceptable emulsifier having an HLB of from about 1 to about 25; and a preservative comprising an organic acid selected from the group consisting of benzoic acid, p-anisic acid, sorbic acid, lactic acid, acetic acid, formic acid, oxalic acid, tartaric acid, salicylic acid and citric acid; wherein said composition has a pH less than 5 and a buffer capacity of between about 0.001 and about 0.039.

The invention discloses an antibacterial pig feed, and belongs to the technical field of feed. The antibacterial pig feed comprises the following components in mass percentage: crop straw 15-30%, sorghum 15-25%, zinc gluconate 1-3%, watermelon rind 20-30%, sodium hydroxycinnamaldehyde sulfonate 10-15%, enteromorpha 15-25%, shell powder 10-20%, anisic acid sugar ester 15-30%, purslane 3-6%, physiological saline 15-25%, loofah vines 10 to 25%, and vegetable oil 5 to 10%. The raw materials of the invention have wide sources and various kinds, and contain various nutrients to satisfy all nutritional needs of an animal growth process. The sodium hydroxycinnamaldehyde sulfonate can not only improve the immunity and antibacterial ability of the animals, but also reduce the occurrence of diseases,and moreover improve the stability of the drug effect; and the sodium hydroxycinnamaldehyde sulfonate and the purslane have antibacterial effects, have a good inhibitory effect on Escherichia coli and Bacillus dysenteriae, and can prevent a variety of infectious diarrhea, and promote the healing of inflammation and ulcer.

According to the present invention there is provided a cosmetic composition comprising a cosmetically acceptable carrier and a preservative system, wherein the preservative system comprises: (i) an antimicrobial agent; (ii) a chelating agent comprising ethylenediamine tetraacetic acid (EDTA) or a derivative thereof; and (iii) an antimicrobial booster agent selected from the group consisting of ethylhexylglycerin, caprylyl glycol, hydroxy acetophenone, caprylhydroxamic acid, phenethyl alcohol, p-anisic acid, glyceryl caprylate, levulinic acid, sodium levulinate, propanediol, hexanediol, pentylene glycol, capryloyl glycine, methylpropanediol, phenylpropanol, sodium anisate, and combinations thereof, wherein the antimicrobial agent is present in an amount of from about 0.001% to about 1% by weight of the composition.

The invention relates to a preparation method of anisic acid with high-efficiency and environment-friendly effects. The preparation method comprises the following steps of using a volatile oil extractor to extract anise oil, mixing the anise oil and a ferric chloride solution, stirring, heating, and dripping an oxidant (hydrogen peroxide) to oxidize the anise oil into the anisic acid. The preparation method has the advantages that the volatile oil extractor is used for extracting the anise oil from star anise, the extraction and enriching are completed, and the operation is simple, convenient and rapid; by using the hydrogen peroxide as the oxidant, and using the ferric chloride as a catalyst, the process of oxidizing the anise oil into anisic acid has the advantages of fewer impurities, high purity, small energy consumption and simple operation; the oxidizing process does not use an organic solvent and a heavy metal catalyst, so that the residue of organic solvent is avoided, and the prepared anisic acid does not contain any other byproducts, and can be directly applied to foods and cosmetics.

The invention relates to an anticorrosive composition and a preparation method thereof, and the anticorrosive composition comprises p-hydroxyacetophenone, sorbitan caprylate, tocopheryl acetate, 1, 2-caprylyl glycol and preservative acid. The preservative acid is one or more of cubilose acid, anisic acid and citric acid. The anticorrosive composition disclosed by the invention contains p-hydroxyacetophenone, sorbitan caprylate, tocopheryl acetate, 1, 2-caprylyl glycol and preservative acid, can effectively inhibit the proliferation and growth of microorganisms, has an obvious preservative effect, and can be used as an important raw material in the fields of corrosion prevention, pharmacy and the like.

The invention relates to feed for feeding syrmaticus humiae in summer and a preparation method of the feed. The feed comprises raw materials in parts by weight as follows: 40-50 parts of corn flour, 20-30 parts of soybean meal, 10-20 parts of bran, 5-10 parts of buckwheat flour, 5-10 parts of acron powder, 1-3 parts of rhizoma athyrii powder, 1-3 parts of pseudocystopeteris atkinsonii powder, 3-5parts of gadfly powder, 0.1-0.5 part of a traditional Chinese medicine component, 0.2-0.3 part of montmorillonite powder and 0.1-0.2 part of medical stone powder. The traditional Chinese medicine component comprises, in parts by weight, 3-5 parts of virgate wormwood herb, 6-8 parts of flos chrysanthemi, 2-3 parts of medicated leaven, 3-5 parts of wrinkled gianthyssop herb, 1-3 parts of rhizoma atractylodis, 1-3 parts of rhubarb, 3-5 parts of pumpkin seeds, 1-3 parts of herba taraxaci and 1-3 parts of anisic acid. The feed is used for feeding the syrmaticus humiae, contains rich Chinese herbalmedicines and microelements, and can meet the requirement of growth and development of livestock and poultry, promote growth of livestock and poultry and enhance immunity of livestock and poultry, sothat the incidence of diseases caused by feed can be reduced, and livestock and poultry eat actively, grow fast and have bright hair color and delicious meat.

The invention relates to a feed mildew-removal agent used for solving the mildew problem of a feed. The mildew-removal agent used for livestock comprises the following ingredients by weight: 0.5-2.0 parts of cinnamaldehyde, 0.5-3.0 parts of dried orange peel, 0.5-2.0 parts of clove, 0.5-2.0 parts of litsea cubeba, 0.5-2.0 parts of lindera glauca, 0.3-1.0 parts of anisic acid, 0.5-2.0 parts of artemisia capillaries, 0.5-2.0 parts of tarragon, 0.5-3.0 parts of sweet wormwood, 0.5-2.0 parts of wild chrysanthemum flower, 0.5-4.0 parts of rehmanniae radix, 0.5-2.0 parts of ligustrum lucidum, 0.5-2.0 parts of gynura bicolor, 1.0-5.0 parts of semen plantaginis, 0.3-1.0 parts of honeysuckle flower, 1.0-5.0 parts of dandelion, 0.5-2.0 parts of Chinese angelica, 1.0-5.0 parts of sheareria nana, 1.0-5.0 parts of rheum officinale and 2.0-20.0 parts of montmorillonite. The feed mildew-removal agent contains abundant Chinese herbal medicines and trace elements, which can supplement the requirement of the growth of the livestock, promote the growth of the livestock and increase the immunity of the livestock. The feed mildew-removal agent has good adsorptivity and disinfection performance to mildew and can effectively reduce the opportunity of mildew in the livestock, thereby the incidence of disease for livestock due to feed can be reduced, and the feed mildew-removal agent is very suitable for modern breeding industry.

The invention relates to a preservative, a preparation method thereof and cosmetics, the preservative comprises: (A) a salt of anisic acid and a weak base, the weak base being selected from matrine, leonurine, lysine, arginine or a combination thereof; (B) a solvent, and the molar concentration of the component (A) is 0.02-0.1 mol / L. According to the preservative provided by the invention, the anisic acid is dissolved in the solvent in the form of salt of the anisic acid and the weak base, so that the problem of low solubility of the anisic acid is solved, and the preservative effect of the anisic acid is enhanced. The preservative serving as a preservative of a natural source is used in cosmetics and does not cause damage to the skin of a human body.

The invention discloses a herbicide composition for forest industry. The composition is prepared from the following raw materials in parts by weight: 20-30 parts of 3,6-dichloro anisic acid, 8-15 parts of Cycloxydim, 23-35 parts of Ethoxysulfuron, 22-25 parts of fluxofenim, 5-10 parts of 2-methyl-4-chlorophenoxyacetic acid, 4-8 parts of glyphosate and 8-15 parts of isoproturon. According to the herbicide composition for forest industry, provided by the invention, the pesticide effect taking speed is high, the pesticide duration is long, and thus, time and labor are saved.

The invention provides a method for preparation of a food preservative by extracting waste liquid by using star anise oil. The method includes the steps that a water phase distillate flowing from an oil-water separator of an star anise oil extraction tank or a water phase distillate collected after re-distillation of claybank muddy waste liquid in the extraction tank is added with sodium chlorideor potassium chloride, a mixture of anisic aldehyde, anisic ketone and anisic acid in the water phase distillate is precipitated, then an organic solvent is added for extraction, then the organic solvent is subjected to reduced pressure distillation to obtain faint yellow oily liquid, the faint yellow oily liquid is cryogenically frozen, precipitated and crystallized and rapidly filtered to obtainthe mixture of the anisic aldehyde, the anisic ketone and the anisic acid, the mixture has antibacterial activity against staphylococcus aureus, escherichia coli, bacillus subtilis, aspergillus niger, aspergillus flavus and penicillium citricum, and has the scavenging effect on DPPH free radical, the aroma is appropriate, and the mixture can be used as the food preservative. The method is easy tooperate, environment-friendly, low in cost, and convenient to use and popularize.

The present invention relates to cosmetic and dermatological formulations comprising a combination of levulinic acid and anisic acid. The formulations according to the invention are particularly suitable for use on the skin. The preparation shows a selective antibacterial effect on skin by specifically resisting anaerobic bacteria of skin flora, and almost has no or no bactericidal effect on aerobic bacteria. Therefore, the composition according to the invention is suitable for cosmetic skin care, as well as for the dermatological treatment of certain skin diseases such as acne.

The invention relates to a low-pollution preparing method of glucose anisate and antibacterial applications of the glucose anisate. Chinese star anise fruits are adopted as a raw material and extracted to obtain anise oil, the anise oil is oxidized to obtain anisic acid, and the glucose anisate is further prepared. According to the method, a volatile oil extractor is utilized to simply and rapidly extract the Chinese star anise fruits to obtain the anise oil so that anise oil extraction and enrichment are completed in one step. Hydrogen peroxide which is a green and efficient oxidant is adopted to prepare the anisic acid, the oxidation efficiency of the hydrogen peroxide is high, the hydrogen peroxide is environmentally friendly, and later-period purification is simple. For preparation of the glucose anisate, a solid organic synthetic process is adopted, a sulfonic acid type solid acid is adopted as a catalyst, no organic solvent is used, high-temperature high-pressure treatment is not needed, and the solid acid can be recovered and reutilized so as to reduce pollution to the environment. The prepared glucose anisate has excellent antibacterial properties.

The invention relates to a natural finishing agent extracted from plants and having antifungal and antiviral functions. The natural finishing agent comprises the following components in parts by weight of 5-25 parts of an olive leaf extracting solution, 5-25 parts of a degraded chitosan solution, 0.5-2 parts of anisic acid, 0.5-2 parts of polydatin, 0.5-8 parts of citric acid, 0.5-2 parts of L-tartaric acid, 0.5-1 part of geniposide, 0.2-0.5 part of degraded konjac glucomannan and the balance of purified water, totaling 100 parts. The natural antifungal and antiviral finishing agent prepared from natural Chinese herbal medicine plant extracting solutions has broad-spectrum antibacterial and fungal pathogen resistance, has an antiviral function, is safe to a human body, does not generate drug resistance and is harmless to the environment. The antifungal and antivirus finishing agent can be used for antifungal and antivirus finishing of textile products such as various fabrics, clothes, bedding, masks and towels and non-woven fabric products.