196 results about "Aceric acid" patented technology

The invention discloses a preparation method of a cell inflammatory factor adsorbent, which comprises the following steps: mixing styrene, divinyl benzene and hydroxyethyl acrylate, and adding a pore-foaming agent and mesoporous SiO2 nano powder to prepare a porous microsphere carrier; the preparation method comprises the following steps: mixing chitosan and poly (N-isopropylacrylamide) in an acetic acid solution to obtain a temperature-sensitive chitosan hydrogel precursor solution; the preparation method comprises the following steps: activating the surface of a porous microsphere carrier by using 1-ethyl-(3-dimethylaminopropyl) carbodiimide and N-hydroxysuccinimide, mixing the activated porous microsphere carrier and a temperature-sensitive chitosan hydrogel precursor solution to obtain a water phase, and assembling, washing and drying in an oil phase to obtain the cell inflammatory factor adsorbent. Through the design of the core-shell structure and the addition of the mesoporous SiO2 nano powder, the temperature response characteristic and the recyclable characteristic are given to the cell inflammatory factor adsorbent, the adsorption capacity of cell factors is also improved, and a new solution is provided for physical adsorption of the cell inflammatory factors.

The present invention discloses a chitosan-modified highly transparent antibacterial polylactic acid film and a preparation method and application thereof. The polylactic acid film comprises the following raw materials by weight: 10 to 16 parts of modified chitosan, 35 to 55 parts of polylactic acid, 5 to 15 parts of casein, 50 to 300 parts of solvent and 30 to 50 parts of gelatin, wherein the solvent comprises hexafluoroisopropanol and acetic acid solution. The antibacterial polylactic acid film provided by the present invention has good toughness, strength and transparency, is suitable for the field of food packaging, can extend the shelf life of food, and can reduce plastic waste pollution.

The invention relates to the technical field of plant polysaccharide extraction, in particular to a process for synergistically extracting rape pollen polysaccharide by a compound enzyme, which comprises the following steps: crushing rape pollen to 200-300 meshes by pulse airflow, performing microwave-ultrasonic degreasing by using a 85% ethanol solution, mixing with an acetic acid-sodium acetate buffer solution with the pH value of 4.8, and performing ultrasonic extraction to obtain a crude extract; the method comprises the following steps: adding a compound enzyme system which is immobilized by Fe3O4 (at) SiO2 nanoparticles by cellulase, pectinase, protease and beta-glucosidase according to a mass ratio of 2: 1: 1: 0.5, carrying out enzymolysis for 4 hours in a 50 DEG C constant-temperature water bath and a 15V / cm pulsed electric field, carrying out enzyme deactivation on enzymatic hydrolysate, carrying out gradient ethanol precipitation, carrying out ultrafiltration deproteinization, and carrying out vacuum pulsation freeze drying to obtain the polysaccharide. According to the method disclosed by the invention, the cell wall breakage rate and the enzymolysis efficiency are improved through pulsed airflow crushing, magnetic nano immobilized enzyme and pulsed electric field assistance, the polysaccharide yield reaches 7.32%, the purity is 91%, the beta-glucosidic bond proportion and the antioxidant activity are remarkably improved, the enzyme can be recycled and reused, the drying time is shortened, and efficient and low-consumption extraction is realized.

The invention relates to the technical field of natural polymer material processing, and discloses a cross-linked composite chitosan solution which is composed of the following components in percentage by mass: 1%-5% of chitosan, 0.1%-5% of a cross-linking agent, 0.1%-5% of acetic acid and the balance of water, and the cross-linked composite chitosan solution is prepared from the following components in percentage by mass: 1%-5% of chitosan, 0.1%-5% of a cross-linking agent, 1%-5% of acetic acid and the balance of water. The cross-linking agent is one or more of glutaraldehyde, citric acid and epoxy chloropropane. According to the cross-linked composite chitosan solution and the preparation method of the chitosan fiber of the cross-linked composite chitosan solution, the adaptability of the cross-linked composite chitosan solution in a human body can be further improved and the immunoreaction can be reduced through a cross-linking reaction, so that the enhancement of the biocompatibility of the cross-linked composite chitosan solution can be ensured; by selecting different cross-linking agents and controlling the cross-linking degree, the biodegradation rate of the chitosan can be adjusted to a certain extent, so that the chitosan is more suitable for specific medical or environmental application requirements, and in addition, the water resistance of the chitosan can be remarkably improved through the cross-linking effect.

The invention relates to the technical field of biological detection, and discloses a mycoplasma pneumoniae nucleic acid rapid detection method, which comprises the following steps: mixing a sample to be detected with a multifunctional pretreatment buffer solution containing tris (hydroxymethyl) aminomethane, potassium acetate, polyethylene glycol, saponin, spermine tetrahydrochloride and tris (2-carboxyethyl) phosphine hydrochloride, and carrying out cracking treatment; a cracking mixed solution is obtained; redissolving the enzymatic isothermal amplification basic reagent, the specific primer and the probe to obtain a redissolving amplification system; sucking the supernatant of the cracking mixed solution, adding the supernatant into a redissolving amplification system, and adding a magnesium acetate solution to obtain a reaction mixed solution to be detected; and carrying out isothermal amplification and signal acquisition to obtain a detection conclusion. The multifunctional pretreatment buffer solution is used for cracking the to-be-detected sample, sample liquefaction, cracking and nucleic acid release are completed in a single system, the nucleic acid extraction and purification step of centrifugal column adsorption or magnetic bead elution is avoided, and the operation process is simplified.

The invention discloses a hydrolysis-resistant catalyst for polyester and a method for producing low-melting-point TPEE by adopting the hydrolysis-resistant catalyst, and the hydrolysis-resistant catalyst is prepared by the following steps in sequence: firstly, weighing 0.5-1.5 kg of chitosan, adding the chitosan into 1kg of organic alcohol BDO, fully stirring until the chitosan is completely dispersed in the BDO, then dropwise adding 100-300g of surfactant monopotassium phosphate, stirring for 30-60 minutes, and then adding 0.5-1.5 kg of organic alcohol BDO, fully stirring until the chitosan is completely dispersed in the BDO to obtain the hydrolysis-resistant catalyst. Dissolving the chitosan solid in the dispersion liquid completely, then adding acetic acid into the solution, and adjusting the pH value to be 5-6 to obtain hydrolysis-resistant liquid; 1.25-2.5 kg of tetrabutyl titanate is weighed and dropwise added into the hydrolysis-resistant solution, full stirring is conducted till no floccules exist in the solution, meanwhile, the temperature of the solution is increased to 60-100 DEG C, negative pressure distillation is conducted under the condition of 10-40 kPa, low-boiling-point substances are removed, the clear and transparent hydrolysis-resistant titanium catalyst is obtained finally, and the titanium content ranges from 6.14% to 6.67%. The method can improve the catalytic efficiency, and effectively solves the problems that the catalyst is easy to hydrolyze to influence the chromaticity of the product and the catalytic activity is uncontrollable.

The invention discloses a method with high catalyst stability for low-pressure carbonyl synthesis of acetic acid from methanol, and relates to the technical field of low-pressure carbonyl synthesis of acetic acid from methanol, and the method comprises the following steps: S1, reaction section: introducing methanol or a reactive derivative thereof and CO into a reactor, adding a group VIII metal catalyst, an iodomethane cocatalyst and inorganic iodide, and carrying out a reaction for 2-4 hours; the preparation method comprises the following steps: by taking a raw material as a raw material and an ionic liquid with a [NR1R2R3R4] < + > [CH3COO] <-> structure as a catalyst stabilizer, carrying out carbonyl synthesis reaction on the material in a reactor to obtain an acetic acid crude product, and in the formula, R1, R2, R3 and R4 are alkyl, aryl and acyl containing 4-9 carbons or a combination thereof; s2, carrying out gas-liquid separation; s3, evaporating and washing; s4, light component removal treatment; and S5, purification treatment, so that the VIII group metal catalyst can still keep stable when reactants are in a reaction system with low water content of 0.5-1.0%, the energy consumption of a rear-end dehydrating tower and a finished product tower is reduced, and the production cost is reduced.

The invention discloses a synthesis method of 5-bromoindole-2-carboxylic acid methyl ester, and the synthesis route comprises the following steps: S1, taking 2-iodo-4-broronitrobenzene and dimethyl malonate as raw materials, and under the catalysis of a solid sulfonic acid resin catalyst, carrying out nucleophilic substitution reaction to prepare 2-(5-bromo-2-nitrophenyl) dimethyl malonate; s2, taking the dimethyl 2-(5-bromo-2-nitrophenyl) malonate prepared in the step S1 as a raw material, taking a ZSM-5 molecular sieve loaded with cobalt acetate as a catalyst, and introducing hydrogen for reduction reaction to prepare a 5-bromoindole-2-carboxylic acid methyl ester crude product; and S3, carrying out recrystallization on the 5-bromoindole-2-carboxylic acid methyl ester crude product prepared in the step S3 by using ethanol, so as to prepare a 5-bromoindole-2-carboxylic acid methyl ester pure product. The synthesis yield is relatively high, the environmental protection property is relatively good, and the prepared 5-bromoindole-2-carboxylic acid methyl ester is relatively excellent in quality and relatively low in cost.

The invention provides a preparation method of dehydronandrolone acetate, and relates to the technical field of medicine synthesis. The dehydronandrolone acetate is prepared by carrying out oxidation reaction on etherates; wherein the preparation of the etherate comprises the following steps: step 1, carrying out esterification reaction on nandrolone to obtain an ester; and 2, carrying out an etherification reaction on the esterified product obtained in the step 1 to obtain an etherified product. According to the method for preparing the dehydronandrolone acetate, the dehydrogenation reaction can be completed at normal temperature, and compared with the prior art, the energy consumption and the operation complexity are remarkably reduced. The method disclosed by the invention is safe and environment-friendly, is convenient for recycling, reduces the recycling cost, avoids the problem of generating high-risk nitrosamine genotoxic impurities, and meanwhile, the chloranil is used as the dehydrogenating agent, and the reduction product is easy to recycle and reuse, so that the production cost is further reduced, and the generation of wastes is reduced.

The present invention addresses the problem of improving the change in smell of stearyl glycyrrhetinate,. This composition is characterized by containing components (A)–(C). (A) Stearyl glycyrrhetinate, (B) niacinamide or tranexamic acid, and (C) at least one compound selected from the group that consists of anisyl alcohol, farnesol, eugenol, citronellol, α-pinene, 1-hexanol (hexen-1-ol), linalool, cedryl acetate, Iso E Super, Sandalore, Ambroxan, γ-terpinene, ambrettolide, β-ionone, borneol, isobutyl quinoline, citral, guaiacol, patchouli alcohol, cedrol, ethyl vanillin, maltol, linalyl acetate, α-terpineol, benzyl benzoate, damascenone, anisaldehyde, benzaldehyde, Magnolan, Mayol, phenylacetaldehyde dimethyl acetal, nerol, dimethyl benzyl carbinol, Bacdanol, methyl anthranilate, Muscenone, benzyl acetate, phenylethyl alcohol, phenylethyl acetate, and heliotropine.

The invention discloses a method for extracting and preparing angelica keiskei exosomes. The method comprises the following steps: S1, selecting an angelica keiskei sample and selecting chitosan; s2, crushing and filtering the angelica keiskei sample to obtain an extracting solution; s3, dissolving chitosan through acetic acid, forming a film through a rotary coater, and carrying out drying and heat treatment; s4, mixing the extracting solution with the dried chitosan membrane, and adsorbing the exosome through the charge effect; s5, putting the chitosan membrane into a tangential flow filtration system, collecting effluent after tangential flow filtration, and purifying the effluent; and S6, pre-freezing the purified solution, and carrying out drying treatment. The invention also discloses application of the method. The method has the beneficial effects that the angelica keiskei sample is crushed and filtered to obtain the extracting solution, then the extracting solution and the dried chitosan film are mixed at room temperature, the exosome is adsorbed through the charge effect, and the exosome is purified after being filtered by the tangential flow filtering system, so that a large amount of high-purity exosome is obtained, and the method is simple, convenient and efficient.

The invention discloses an aldehyde removal tower for removing aldehyde impurities in acetic acid, and relates to the field of aldehyde removal towers, the aldehyde removal tower comprises an aldehyde removal tower body, an alcoholization assembly is fixedly mounted on the upper side in the aldehyde removal tower body, a flow dividing frame A is mounted at the bottom of the alcoholization assembly, a secondary aldehyde removal filter plate is arranged below the flow dividing frame A, and a one-way hopper is mounted at the bottom of the secondary aldehyde removal filter plate; a diversion frame B is installed below the one-way hopper, an evaporation channel is arranged at the bottom of the diversion frame B, an acetic acid collecting pool is fixedly arranged at the bottom of the evaporation channel, and a steam inlet is formed in the side wall of the top of the acetic acid collecting pool. According to the dealdehyding tower for removing the aldehyde impurities in the acetic acid, separation is carried out by utilizing the difference of boiling points of alcohols and the acetic acid, so that the alcohols and other impurities can be fully vaporized, and the acetic acid is less vaporized, so that effective separation of the alcohols and the acetic acid is realized; the acetic acid solution collected in the acetic acid collecting tank is high in purity, a pure acetic acid product can be obtained, and the requirement of industrial production for the purity of acetic acid is met.

The invention relates to a method for accurately controlling the acetyl substitution degree of cellulose acetate, which comprises the following steps: adding ground wood pulp into a reaction kettle, adding acetic acid, stirring at room temperature, then adding acetic acid, acetic anhydride and sulfuric acid, mixing, starting acetylation reaction, and gradually raising the system temperature in the reaction process. After reacting for a period of time, stretching a probe of an on-line infrared instrument into the reaction kettle to collect infrared spectrum data on line, adding a magnesium acetate solution, and starting hydrolysis reaction; adding part of the magnesium acetate solution and water after a period of time, maintaining for a period of time, adding part of the magnesium acetate solution after the relative esterification degree monitored by an online infrared instrument reaches a target value, and terminating the hydrolysis reaction; compared with the prior art, the hydrolysis reaction endpoint can be accurately identified on line, esterification degree fluctuation caused by inaccurate reaction time control is avoided, the production efficiency and economic benefits are improved, and the product quality is favorably improved.

The invention relates to the technical field of chemical engineering, and discloses a method for improving the chromaticity and purity of acetic anhydride based on a reflux ratio, and the method comprises the following steps: optimizing an evaporation tower, an acetic acid rectifying tower and an acetic anhydride rectifying tower, and installing an online detection instrument and an automatic control valve to construct an intelligent rectification control system; evaporating the crude acetic anhydride by using the optimized evaporation tower to obtain crude acetic anhydride steam; feeding the crude acetic anhydride steam into an acetic acid rectifying tower, calculating an initial reflux ratio, inputting the initial reflux ratio into a control system, and starting a reflux system to preliminarily remove acetic acid; monitoring the acetic acid content through an online gas chromatograph, and finely adjusting the reflux ratio until the reflux ratio reaches the standard when the measured acetic acid content is higher than a target value; feeding the crude acetic anhydride reaching the standard into an acetic anhydride rectifying tower, calculating an initial reflux ratio, inputting the initial reflux ratio into a control system, and starting to obtain an intermediate product; monitoring chromaticity and purity through an on-line platinum-cobalt colorimeter and an on-line gas chromatograph, and updating the reflux ratio to be qualified according to a bivariate adjustment formula; and finally, carrying out all-item detection on a finished product, and locking reflux ratio parameters after confirming that the finished product is qualified.

The present invention provides a method for preparing a high-purity and high-yield abiraterone acetate intermediate. The preparation method of the present invention comprises the steps of: (1) detecting the water content of raw material iodine: reacting zinc powder with iodine in solvent A, filtering and removing solids, and using Karl Fischer method to determine the water content N1 in the filtrate; performing a blank control experiment without iodine addition at the same time, using Karl Fischer method to determine the water content N2 in the filtrate in the blank control experiment, and calculating the water content of raw material iodine; (2) adding solvent B, iodine, and acetic anhydride to a container, stirring the reaction, adding tetramethylguanidine, adding dehydroepiandrosterone-17-hydrazone I, performing iodination reaction, and obtaining abiraterone acetate intermediate 17-iodo-androsta-5,16-diene-3β-alcohol II; the abiraterone acetate intermediate obtained by the method of the present invention has high yield and high purity.

The utility model provides a solid acetic acid homogenizing fermentation drum which comprises a fermentation drum body, a feed port, a liquid inlet, a stainless steel pipe, a flange, a heating belt, an electric slip ring, a rack, a motor transmission system and a transmission shaft. Raw materials are conveyed through the left-side pipeline, wine and acetic bacteria are conveyed through the right-side pipeline, and mechanical conveying of the raw materials is achieved; a temperature control device is arranged, so that the temperature of vinegar grains in the fermentation drum can be monitored in real time to determine a fire point; a heating belt is wound on the drum body, and the drum body is wound through an electric slip ring and a heating belt connector, so that the entangling phenomenon can be avoided when the fermentation drum rotates forwards and backwards, and materials in the drum can be heated to reach a proper fermentation temperature; a rack is arranged below the rotary drum, transmission shafts are arranged on the periphery of the rack, and the fermentation rotary drum is positively and negatively rotated through rollers, so that the fermentation uniformity of vinegar grains in the rotary drum is ensured. According to the utility model, the problems of more required equipment and manpower and unstable acetic fermentation in the acetic fermentation stage are solved.

The invention discloses a machine learning assisted acetic acid reaction rate prediction model training method and device and a prediction method. The machine learning assisted acetic acid reaction rate prediction model training method comprises the following steps: acquiring an enhanced data training set; extracting a training feature vector of the enhanced data training set; obtaining a classification promotion regression model for the acetic acid reaction rate; and training the classification lifting regression model for the acetic acid reaction rate through the feature vectors for training so as to obtain the trained classification lifting regression model for the acetic acid reaction rate. According to the method, a model relationship between input characteristics and acetic acid reaction rates (including reactant mass, catalyst mass, methyl acetate concentration and the like) is established through training set learning. A user can directly obtain the prediction result of the acetic acid reaction rate by inputting the characteristic variables.

The invention relates to a pharmaceutical intermediate (S)-9-(2, 3-di-O-acetyl propyl)-N2-acetyl guanine and a synthesis method thereof.In the synthesis method, a compound 2 serves as a starting material, sodium acetate, acetic acid and acetic anhydride are added, reaction, concentration and column chromatography purification are performed at the temperature of 110-130 DEG C, and the target product (S)-9-(2, 3-di-O-acetyl propyl)-N2-acetyl guanine is obtained. The invention relates to 2, 3-di-O-acetyl propyl)-N2-acetyl guanine. The invention discloses a novel medical intermediate and designs a feasible synthesis process, through the synergistic effect of all reagents, the reaction can be stabilized under mild conditions, side reactions are effectively avoided, the purity and stability of the product are ensured, and a foundation is laid for popularization of new drugs.

The utility model relates to the technical field of chemical separation, in particular to a dual-purpose extractive distillation tower for separating acetic acid from water, which comprises an extraction tower, a condenser I, a condenser II and a reboiler, an extraction chamber, a distillation chamber and a circulation chamber are arranged in the extraction tower, the distillation chamber and the extraction chamber are symmetrically arranged, and the circulation chamber is positioned below the distillation chamber and the extraction chamber. The first condenser and the second condenser are located above the extraction tower, the first condenser is communicated with the extraction chamber, the second condenser is communicated with the rectification chamber, and by integrating the two functions of extraction and rectification, the tower achieves effective separation of acetic acid and water. The layered contact design ensures that the acetic acid raw material and the composite extraction agent are in full contact but not directly mixed between filler layers, the mass and heat transfer process is optimized, the extraction agent can be recycled after being treated by the rectification chamber, and the resource waste is remarkably reduced. And due to the recycling design, the operation cost is reduced, and the consumption of the extracting agent is reduced.

The invention provides high-activity crataegus pinnatifida fruit vinegar and a preparation method thereof.The preparation method comprises the steps that crataegus pinnatifida fruits are juiced, then a composite chelating agent composed of polyglucuronic acid and monopotassium phosphate is added for chelating treatment, and a polysaccharide-metal ion cross-linked network is removed; then adding endo-beta-1, 4-glucanase to carry out linear polysaccharide directional enzymolysis, so that the viscosity of the fruit juice is obviously reduced; after the components are adjusted, double modified yeast beta-glucan microspheres are added, yeast is inoculated for alcoholic fermentation, the microspheres are subjected to double grafting modification through galactooligosaccharide and theaflavin, and active components in the crabapple can be directionally captured and stabilized through hydrophilic and hydrophobic effects respectively; after alcohol fermentation is finished, acetic bacteria are inoculated for acetic fermentation, and finally, filtering and sterilization are performed. According to the method disclosed by the invention, by virtue of a synergistic strategy of breaking a network firstly, then carrying out enzymolysis debonding and then carrying out microsphere loading, the fermentation mass transfer efficiency is effectively improved, and meanwhile, the retention rate of functional components such as polyphenol and saponin in the fruit vinegar is increased.

This application provides a method for preparing pH-responsive polyamino acid drug-loaded nanoparticles based on sarcosine and their application. Sar-NNCA, L-lysine-NCA, and L-phenylalanine-NCA are dissolved in anhydrous DMF and polymerized under argon protection with a hexamethyldisilazine initiator to obtain a polyamino acid block copolymer Sar-NNCA. 80 -Lys(Cbz) n -Phe 10 The crude product was deprotected under HBr / acetic acid and loaded with DOX to obtain Sar. 80 -Lys n -Phe 10 -DOX. This application describes the preparation of a pH-responsive polymer nanoplatform, Sar, by encapsulating doxorubicin in polysarcosine-polylysine-polyphenylalanine nanoparticles via Schiff base bonds. 80 -Lys n -Phe 10 -DOX is used for tumor treatment. These polyamino acid nanoparticles are spherical with an average particle size of approximately 200 nanometers, exhibiting pH-responsive properties, excellent cellular uptake capacity, and anti-tumor effects. In vitro experiments show that Sar... 80 -Lys n -Phe 10 The carrier material exhibits excellent biocompatibility. The newly synthesized Sar... 80 -Lys n -Phe 10 -DOX nanomicelles show promise as a drug delivery system for cancer treatment.

The invention relates to the field of interior wall putty, and particularly discloses flame-retardant environment-friendly interior wall putty. The adhesive is prepared from the following raw materials in parts by mass: 10 to 20 parts of oxidized starch, 10 to 20 parts of guar gum, 10 to 15 parts of special adhesive powder for putty, 5 to 7 parts of carboxyl-terminated hyperbranched polyester, 1 to 3 parts of chitosan, 3 to 5 parts of graphene oxide, 3 to 5 parts of hydroxypropyl methyl cellulose ether, 3 to 5 parts of starch, 1 to 3 parts of sodium stearate, 1 to 3 parts of sodium hexametaphosphate, 1 to 3 parts of water glass, 1 to 3 parts of borate and 1 to 3 parts of nano antimony trioxide. 1-5 parts of coarse whiting, 1-3 parts of acetic acid aqueous solution with the mass fraction of 8-12%, 1-3 parts of ethanol, 1-3 parts of glycerol and 0.1-0.3 part of preservative. The invention also discloses a preparation method of the flame-retardant environment-friendly interior wall putty. The natural material guar gum is adopted and has a synergistic effect with various materials, so that the stability and flame retardance of a system are effectively enhanced.

The invention provides a low-energy-consumption separation system in acetic acid production. The low-energy-consumption separation system comprises a rectification module, a heat energy integration module, a steam separation module, an energy conversion module and an energy guide pipeline, a rectification module is taken as a core, after steam at the top of a light component removal tower is treated by a heat energy integration module, secondary steam is divided into two paths by a steam dividing module: the first path is conveyed to a rectification module reboiler group through an energy guide pipeline; and the second path enters the energy conversion module and is processed by the generator set and the collection and transmission set, and then liquid of the tail end gas-liquid separator is connected back to the heat energy integration module through a pipeline to form a closed-loop energy circulation system. By means of the system, energy consumption can be greatly reduced, and good economic benefits and environmental protection benefits are achieved.

The invention discloses a peach ketone synthesis method, which relates to the technical field of essence and perfume synthesis, and comprises the following steps: adding cyclopentanone and glacial acetic acid into a reaction container, starting stirring, adding manganese acetate (II) and cobalt acetate (II), and then adding acetic anhydride; introducing dried air below the liquid level, heating to 80-100 DEG C, dropwise adding D-limonene, and carrying out a heat preservation reaction after dropwise adding is finished; gC monitors the reaction endpoint, and the reaction is stopped when the product purity of the reaction liquid is not increased any more; after the reaction is finished, filtering, carrying out reduced pressure distillation to recover cyclopentanone, glacial acetic acid and unreacted D-limonene, after the recovery is finished, adding methanol and n-heptane into kettle liquid, carrying out water extraction, washing and liquid separation, washing an organic phase with a sodium bicarbonate aqueous solution, carrying out reduced pressure distillation on the organic phase to recover n-heptane, and after the recovery is finished, obtaining a peach ketone crude product; and carrying out crude drawing and rectification on the peach ketone crude product to obtain a peach ketone finished product. The method has the advantages of mild reaction conditions, low safety risk and few three wastes, and can obtain a high-purity peach ketone finished product.

The present invention relates to a method for determining enantiomers of polypeptide protected amino acids. Compared with the prior art, a normal phase chromatographic column is not used to determine enantiomers using n-hexane and isopropanol / ethanol as a mobile phase system; instead, a reverse phase chiral chromatographic column with a surface coated with cellulose-tris(4-methylbenzoate) filler is used, and ammonium acetate solution-acetonitrile is used as a mobile phase for gradient elution; under the chromatographic conditions, enantiomers and main components can be effectively separated, and a buffer salt is used as a mobile phase, and the target peak is sharp and easy to judge and detect; and the ammonium acetate and acetonitrile used in the mobile phase system are both conventional reagents, which are easy to obtain, thereby reducing the detection cost.

The invention belongs to the technical field of phosphatidylserine production, and particularly relates to immobilized phospholipase D based on biological imprinting and a preparation method and application thereof. The preparation method comprises the following steps: S1, dissolving L-serine in an acetic acid buffer solution to obtain a serine solution, adding a phospholipase D solution into the serine solution, and stirring to obtain a mixed solution; s2, adding sodium alginate into the mixed solution, stirring and dissolving to obtain a biopolymer solution; s3, adjusting the pH value of the chitosan solution to be neutral, then adding CaCl2 into the chitosan solution, and stirring and dissolving to obtain a CaCl2-containing chitosan solution; and S4, dropwise adding the biopolymer solution into a chitosan solution containing CaCl2, complexing to form microspheres, collecting the microspheres, and washing and drying the microspheres to obtain the immobilized phospholipase D based on biological imprinting. According to the method, the biological imprinting technology and the enzyme immobilization technology are combined, the immobilized PLD with high selectivity and high stability is prepared, and the phosphatidyl transfer reaction efficiency is improved.

The utility model provides an RO (Reverse Osmosis) acetic acid recovery system. The RO acetic acid recovery system comprises an RO water inlet buffer tank, a primary reverse osmosis membrane group and a secondary reverse osmosis membrane group, the liquid inlet end of the RO water inlet buffer tank is connected with an RO water inlet pipe; the output end of the buffer tank is sequentially connected with a reverse osmosis low-pressure pump and a reverse osmosis high-pressure pump through a conveying pipeline; the output end of the reverse osmosis high-pressure pump is connected with the primary reverse osmosis membrane group through a pipeline; one end, provided with a double-pipeline output end, of the second-stage reverse osmosis membrane group is connected with a liquid inlet end of the first-stage RO water production tank, and the other end of the second-stage reverse osmosis membrane group is connected with a liquid return opening of the RO water inlet buffer tank; the penetrating fluid conveying pump is connected with the sewage treatment device through an output pipeline; and a conveying pipeline connected with a liquid return port of the secondary RO water production tank is arranged on the output pipeline between the penetrating fluid conveying pump and the sewage treatment device. According to the RO acetic acid recovery system disclosed by the utility model, the recovery rate of acetic acid in water is improved, the consumption of fresh acetic acid is reduced and considerable economic benefits are brought to enterprises by arranging two groups of reverse osmosis membrane group operation loads.

The invention discloses a method for producing volatile fatty acid by improving microbial electro-catalytic conversion of CO2. The core of the method is to construct an efficient and stable heterozygote biological cathode. The method comprises the following steps: inoculating flora mainly comprising Acetobacter burgii and Desulfurization Vibrio in a cathode chamber of an H-type microbial electrosynthesis reactor, and adding a zinc source and a sulfur source to synthesize ZnS nanoparticles in situ on the surfaces of cells, so as to construct the bacterium and ZnS nanoparticle heterozygote biological cathode. The acetic acid yield of the heterozygote biological cathode can reach 3.38 mmol / L / d, and the accumulative yield of one batch is 20.25 mmol / L, which is 2.7 times that of an unmodified carbon cloth biological cathode; the coulombic efficiency of the total volatile fatty acid product reaches 96.47% and is 1.25 times that of a carbon cloth biological cathode; and the coulombic efficiency of acetic acid and the selectivity of acetic acid are respectively improved to 83.27% and 86.32%, which are obviously higher than 40.63% and 52.64% of those of a carbon cloth biological cathode. In addition, the charge transfer resistance of the heterozygote biological cathode is as low as 3.75 ohm and is obviously superior to that of a carbon cloth biological cathode (25.28 ohm), so that long-term stable and high-selectivity acetic acid production is realized.

The invention discloses a component traditional Chinese medicine preparation for treating moderate and severe uterine prolapse, which is prepared from the following components in percentage by mass: 2.5 to 3.5 percent of rhizoma bletillae gum, 1.0 to 2.0 percent of centella asiatica total glycosides, 0.3 to 0.6 percent of fructus cnidii oil, 0.2 to 0.5 percent of cinnamon oil, 0.001 to 0.005 percent of NP-700 type sodium polyacrylate, 0.35 to 0.65 percent of B type carbomer, 4.5 to 7.5 percent of glycerol, 0.35 to 0.65 percent of triethanolamine, 0.05 to 0.09 percent of chlorhexidine acetate and the balance of purified water. The sum of the mass percentages of the components is 100%. The specific preparation method comprises the following steps: weighing the components, dissolving, mixing, adjusting the pH value, and forming. The traditional Chinese medicine preparation is used for preparing medicines for treating moderate and severe uterine prolapse, has the effects of warming yang and promoting tissue regeneration, and can repair degenerated and damaged pelvic floor muscle groups by promoting collagen expression, extracellular matrix generation and muscle cell proliferation in pelvic floor tissues after vaginal administration; the structural strength and supporting tension of pelvic floor tissue are improved, the supporting and lifting effect on the uterus is recovered, and the prolapsed uterus is stably reset.