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Factor X, also known by the eponym Stuart–Prower factor, is an enzyme (EC 3.4.21.6) of the coagulation cascade. It is a serine endopeptidase (protease group S1, PA clan). Factor X is synthesized in the liver and requires vitamin K for its synthesis.
Bispecific Factor VIII mimetic antibody
ActiveCN115052898BImmunoglobulins against blood coagulation factorsBlood disorderAntiendomysial antibodiesFactor X
The present invention relates to bispecific antibodies that can bind to coagulation factor IX (FIX) and / or its activated form factor IXa (FIXa) and factor X (FX) and / or its activated form factor Xa (FXa) and promote the activation of FX by FIXa, as well as methods and compositions for treating subjects suffering from coagulopathy such as hemophilia A with or without inhibitors.
Owner:NOVO NORDISK AS
Combination of factor vii and a Anti-factor ix and factor x bispecific antibody
A pharmaceutical composition comprising: a. transgenic Factor VII and b. a multispecific antibody directed against Factor IX and Factor X. The patent application contains 10 more claims.
Owner:LABE FR DU FRACTIONNEMENT & DES BIOTECH SA