The application discloses application of a
copper-containing compound in preparation of a
medicine for preventing and / or treating
obesity and related metabolic diseases. The application breaks through the traditional
cognition on safety of high-
dose copper, and proves that
oral administration of the
copper-containing compound (such as
copper chloride) in a specific
dose range (calculated according to copper element, such as 0.07-2.84 mg / kg
body weight per day) can effectively inhibit
weight growth of animals induced by a high-
fat diet, and simultaneously has an effect on
liver steatosis and
body composition, without risk of
liver toxicity. Compared with existing
weight loss methods, the application scheme has the advantages of low
raw material price, convenient oral use, wide safety window, remarkable comprehensive effect and the like, and provides a clear direction and a
solid experimental basis for development of a new, economical and safe
medicine or health care food for preventing and treating
obesity.