34 results about "Weight growth" patented technology

The invention relates to pediococcus acidilactici XZ106, which is classified and named as pediococcus acidilactici, and is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC No.30094, the preservation date is March 22, 2024, and the preservation address is No.3, Yard 1, Beichen West Road, Chaoyang District, Beijing. The pediococcus acidilactici XZ106 can (1) relieve insulin resistance, regulate insulin and glucagon secretion and improve liver gluconeogenesis, so that diabetes hyperglycemia is improved; (2) weight gain, fat accumulation and liver lipid accumulation of obese mice are inhibited, glycolipid metabolism disorder of the mice is improved, and the composition has excellent effects of reducing fat and relieving obesity; (3) the level of IL-10 can be remarkably improved, and the anti-inflammatory ability of mice is improved; (4) vascular injury is reduced, so that diabetic complications and various cardiovascular diseases of atherosclerosis are prevented.

The invention relates to the technical field of microorganisms, in particular to enterococcus faecalis EF-1 capable of reducing blood lipid, a microbial preparation and application of the enterococcus faecalis EF-1. The enterococcus faecalis EF-1 is preserved in the China General Microbiological Culture Collection Center (CGMCC) on September 27, 2024, and the preservation number is CGMCC No.32097. The enterococcus faecalis EF-1 is named as enterococcus faecalis EF-1. The enterococcus faecalis EF-1 has the functions of: (1) relieving the weight increase speed of animals, reducing body weight gain, and preventing, relieving or treating obesity; (2) the contents of triglyceride, cholesterol and low-density lipoprotein cholesterol in liver and serum are reduced; (3) the liver function is protected, and the contents of ALT and AST in serum and liver are reduced; (4) liver lipid deposition and lesion are relieved; (5) relieving adipose tissue hypertrophy; (6) preventing, relieving or treating metabolic syndrome; (7) reducing blood sugar, improving insulin resistance and relieving diabetes mellitus; 8, increasing the content of short-chain fatty acid; and (9) regulating intestinal flora.

The invention provides an application of a GluN3B inhibitor in preparation of drugs for preventing or treating obesity and related metabolic syndromes. The invention provides application of a GluN3B inhibitor in prevention and treatment of obesity. A food-induced obesity model rich in fat (the proportion is 45%) is taken as a research object, and the GluN3B gene knockout or knockdown can effectively inhibit the weight gain of mice. In-vivo animal experiments show that the knockout or knockdown of the GluN3B gene can activate brown adipose tissues to remarkably promote energy consumption of mice, which is an important reason for causing slow weight growth of the mice.

The invention belongs to the technical field of aquaculture, and particularly relates to application of resveratrol in culture of penaeus vannamei boone, which is characterized in that the application dosage and mode of the resveratrol are that the penaeus vannamei boone is fed according to the weight proportion of 0.033-0.067 per thousand of the total weight of the penaeus vannamei boone everyday. The resveratrol is used for improving the immune function of penaeus vannamei boone, improving the survival rate, increasing the body weight growth rate and counting immune cells. The resveratrol is also used for improving the anti-oxidative stress capability of the South America white, including improving the superoxide dismutase activity of the shrimp body, and / or improving the shrimp hepatopancreas lysozyme activity of the shrimp body, and / or improving the total anti-oxidative capability of the shrimp body. The resveratrol can enhance the immune epidemic prevention level of the penaeus vannamei population on stress sources such as vibrio infection, reduce the oxidative stress risk of the penaeus vannamei population and avoid the expansion of breeding loss caused by group stress.

The present application relates to use of Ligilactobacillus salivarius in preparing a drug for preventing and / or treating diseases associated with overweight and / or obesity . The strain can inhibit the weight growth of a high-fat diet-induced obesity model mouse, reduce the blood lipid level of the high-fat diet-induced obesity model mouse, improve the liver injury index of the high-fat diet-induced obesity model mouse, reduce the area of white adipose cells of the high-fat diet-induced obesity model mouse, improve the colon GLP-1 level of the high-fat diet-induced obesity model mouse, improve the intestinal flora imbalance of the high-fat diet-induced obesity model mouse, and improve the liver glycolipid metabolism of the high-fat diet-induced obesity model mouse; and reduce the waist circumference, hip circumference, body fat mass, BMI, and weight of overweight and overweight and / or obesity volunteers, and maintain the muscle content, promoting overweight and overweight and / or obesity people to carry out safe, effective, and sustainable weight management.

The invention relates to the technical field of animal nutrition information modeling, in particular to a chicken nutrition modeling and visual analysis system which comprises a nutrition requirement evaluation module, a proportion optimization calculation module, a nutrition trend analysis module, a proportion adjustment module and a nutrition diagnosis decision module. According to the method, accurate description of a nutritional demand structure is realized through the weight growth rate and the change trend of the ingestion behavior, efficient matching of feed energy and protein content is assisted by extracting a comparison result of absorption fluctuation and demand intensity, a high-frequency demand stage is identified according to the time sequence characteristics of the weight fluctuation, and dynamic tracking of a nutritional demand period is realized. According to the method, the feed matching value is revised in a segmented mode according to the ingestion time delay and the absorption difference, so that the matching response is close to the growth rhythm, the nutrition attribution path is recognized through the absorption difference and the fluctuation rule, the nutrition supply adaptability and the ingredient pertinence are improved, the feed waste rate and the nutrition imbalance probability are reduced, and the feeding benefit and the management intelligent level are improved.

The present disclosure provides an aquarium feed with slow-release function, and preparation method and uses thereof. Raw materials of the aquarium feed comprise granulated feeds with different particle sizes and slow-release binding agent; the granulated feeds with different particle sizes are bonded by the slow-release binding agent; the slow-release binding agent contains attractant and slow-release adhesive; and the slow-release adhesive is gel-like in water. The aquarium feed in the present disclosure can be slowly released into tiny particles with uneven size in water, allowing aquarium creatures with different body sizes or living in different water layers (comprising surface, middle and bottom layers) to find suitable food for themselves, thus improving the feed utilization rate and aquarium creatures' weight growth rate, and reducing difference of the body length.

The invention relates to the technical field of aquaculture, in particular to an accurate regulation and control method for micropterus salmoides culture water quality. According to the micropterus salmoides culture water quality regulation and control method, a culture water body meets one or more of the following conditions: (1) adding photosynthetic bacteria into the culture water body every day, and controlling the final concentration of the photosynthetic bacteria in the water body to be 10 < 6 >-10 < 7 > CFU / mL; (2) adjusting the content of dissolved oxygen in the culture water body to 5.5-7.5 mg / L; (3) adjusting the temperature of the culture water to 26 + / -1 DEG C in the daytime and 23 + / -1 DEG C at night. The total nitrogen, total organic carbon and chemical oxygen demand can be obviously reduced through day and night temperature regulation and addition of photosynthetic bacteria, the water change demand is reduced, and the eutrophication risk is reduced; meanwhile, the specific growth rate (SGR) and the weight growth rate (WGH) are improved, the immune and antioxidant indexes are optimized, and the aeration energy consumption is reduced by controlling dissolved oxygen to be 7.0 mg / L.

The present application belongs to the field of veterinary medicine, and specifically discloses a traditional Chinese medicine composition for preventing and treating chicken infectious bronchitis, a preparation method and application thereof. The traditional Chinese medicine composition is composed of the following raw materials in parts by weight: Ephedra 12 parts, apricot kernel 12 parts, licorice 9 parts, coix seed 30 parts, forsythia 12 parts, honeysuckle 20 parts, white eupatorium 12 parts, smilax 20 parts, and purple violet 6 parts. The composition can be used for preventing and treating artificially infected IBV chicks, and can significantly improve the survival rate of chicks, alleviate the decrease in body weight growth caused by IBV, relieve clinical symptoms, reduce the viral load in trachea and kidney tissues, reduce organ pathological damage, and promote the recovery of the body. The traditional Chinese medicine composition for preventing and treating chicken infectious bronchitis is easy to obtain, rich in resources, low in cost, safe, non-toxic and non-residual, and the preparation method is simple and suitable for large-scale production.

The invention discloses a method for establishing a rat artificial feeding model, and belongs to the technical field of biomedicine. The method specifically comprises the following steps: 1) selecting a plurality of newly born SD suckling rats, and averagely dividing the rats into an artificial feeding group and a breast feeding group; 2) preparing artificial milk; each SD suckling mouse in the artificial feeding group is artificially fed through the suckling mouse feeding device; (3) the SD suckling rats and the female rats in the breast feeding group are placed in the same space, and manual intervention is not carried out; and (4) the artificial feeding group and the breast feeding group continue to the weaning period, a weight growth curve of the SD suckling rats is drawn, and if the weight growth curve of the artificial feeding group and the breast feeding group have no obvious statistical difference and the death rate is lower than 0.1%, the artificial feeding suckling rat model is successfully established. The model provides feasible animal model support for research on health outcomes of different life development stages of individuals influenced by environmental factors in early life, and can deeply discuss a potential mechanism of influence of milk powder feeding and breast feeding on individual growth and development.

The invention discloses a computer-based pig feed formula data optimization processing method and a computer-based pig feed formula data optimization processing system, and relates to the technical field of breeding management. According to the method, by constructing a growth curve expansion algorithm model and combining individual data of pork pigs and microbial metabolic activity data, the weight gain of the pork pigs can be predicted; and further calculating the nutritional requirement Dn of each growth stage. Compared with a traditional method for formulating a feed formula depending on experience or a static model, the method has the advantages that the daily nutritional requirements are calculated in real time through the growth curve extension algorithm model, so that the feed formula is adjusted more accurately. And when the nutritional demand Dn exceeds a preset nutritional demand threshold value, the system can automatically trigger a feed formula optimization mechanism and output the adjusted feed demand Fi, so that the growth demand of the pork pigs is met. Through the dynamic adjustment, the pork pigs can obtain the nutrition proportion most suitable for the current growth stage, and the problem that health and growth speed are affected due to overnutrition or insufficient nutrition is avoided.

The present invention discloses a method for establishing an artificial feeding model for rats, which belongs to the field of biomedical technology. Specifically: 1) select a number of newly born SD suckling mice and divide them into an artificial feeding group and a breast feeding group on average; 2) prepare artificial milk; artificially feed each SD suckling mouse in the artificial feeding group through a suckling mouse feeding device; 3) the SD suckling mice and the mother mice in the breast feeding group are placed in the same space without artificial intervention; 4) the artificial feeding group and the breast feeding group are continued until the weaning period, and the weight growth curve of the SD suckling mice is drawn. If there is no significant statistical difference between the weight growth curve of the artificial feeding group and the breast feeding group, and the mortality rate is less than 0.1%, the artificial feeding suckling mouse model is successfully established. This model provides a feasible animal model support for exploring the impact of environmental factors in early life on the health outcomes of individuals at different life development stages, and can deeply explore the potential mechanism of the impact of breastfeeding on individual growth and development compared with formula feeding.

The invention discloses a method for establishing an animal model for long-term obesity of offspring caused by excessive feeding, and belongs to the technical field of biomedicine. The method specifically comprises the following steps: 1) selecting a suckling SD female mouse with a good health condition and 2-4 newly born SD suckling mice with normal vital signs to form an excessive feeding group; the method comprises the following steps: selecting a lactating SD female mouse with good health condition and 10-14 newly born SD suckling mice with normal vital signs to form a normal feeding group, and feeding in the same cage; (2) in the same-cage feeding process, except for supplying sufficient feed and water to the SD female rats, intervention of other people is not carried out; and 3) drawing weight growth curves of the two groups of SD suckling rats, and if the weight growth curve of the overfeeding group is obviously higher than that of the normal feeding group and the death rate of the SD suckling rats of the normal feeding group is lower than 0.1%, successfully establishing the animal model of long-term obesity of the offspring caused by overfeeding. The model provides feasible animal model support for research on exploration of influence of early life environment factors on obesity of individuals in different life development stages.

The application discloses a method for relieving the adverse effects of chronic restraint stress on animals by adding sodium isovalerate into feed, which comprises taking C57BL / 6J mice as research objects, studying the effects of sodium isovalerate on growth performance, depression behavior and intestinal barrier and inflammation indexes of the mice with chronic restraint stress, recording daily weight gain and feed intake, and performing tail suspension test and Elisa test and other test methods, and proving that sodium isovalerate can relieve the decrease of mouse weight growth rate, the increase of feed to weight ratio and the decrease of organ index caused by CRS; through fluorescence quantitative PCR and Western Blot and other methods, it is proved that sodium isovalerate can relieve the intestinal injury of the CRS mice, reduce the expression of colon pro-inflammatory factors and improve the expression of tight junction proteins, and can also reduce the phosphorylation level of NF-kappa B in the colon of the CRS mice. The application explores the relieving effect of sodium isovalerate on chronic restraint stress of animals, so as to provide some theoretical basis for relieving stress in actual production and the application of sodium isovalerate in feed additives.

The present invention relates to a method and apparatus for predicting the weight growth rate and mature weight of plant fruits. Specifically, the present invention provides a method for constructing a prediction model for the weight growth rate or mature weight of plant ears, seeds, or fruits. This method can quickly and accurately determine the weight growth rate and mature weight of plant ears, seeds, or fruits by using respiration rate without removing or damaging the plant.

The invention discloses an sNPF gene and application of an inhibitor of the sNPF gene in prevention and control of beet armyworms, and belongs to the technical field of biology. The sNPF gene of the beet armyworm is silenced through an RNA interference technology, and the sNPF is found to play an important regulation role in ingestion, growth and development and energy metabolism of larvae; the sNPF gene silencing obviously reduces the feeding amount and the body weight growth rate of the larvae, and increases the death rate of the larvae under hunger stress; in addition, silence of the sNPF gene also significantly affects the content of glycometabolism substances in the larva body. The sNPF is found to be a key factor for regulating and controlling the physiological process of beet armyworm larvae, has the potential of serving as a new target for pest control, and provides a theoretical basis for prevention and control of beet armyworms.

The invention discloses a meat rabbit feeding device with a feed efficiency measuring function, and belongs to the technical field of meat rabbit breeding. The meat rabbit feeding device comprises a feeding cage, a base is arranged at the bottom of the feeding cage, and a mounting frame is mounted at the bottom of the base; according to the meat rabbit feeding device with the feed efficiency measuring function, the first weighing module can conduct real-time weighing on the weight of meat rabbits, the second weighing module can conduct real-time weighing on the weight of feed in the feeding trough, data of the feed consumed by the meat rabbits every day can be transmitted to remote processing equipment in a wired or wireless mode, and the meat rabbits can be fed to the remote processing equipment in a wired or wireless mode. The daily weight increase data of the meat rabbits can be transmitted to the remote processing equipment in a wired or wireless manner, and the remote processing equipment can calculate the feed consumption and the weight increase of the meat rabbits through a corresponding system, so that the meat increase rate of different brands of feed fed with the same weight of feed at the same time can be calculated; the meat rabbit feeding device has the function of measuring different feed efficiencies.

The invention discloses application of hippuric acid in activation of brown adipose tissue heat production and prevention and treatment of obesity, and the application is realized by activating brown adipose tissue heat production, specifically, expression of uncoupling protein 1 in brown adipose tissue is up-regulated, heat production capacity under cold stimulation conditions is enhanced, weight gain and abnormal glucose and lipid metabolism are improved, and the purpose of preventing and treating obesity is achieved. The hippuric acid is preferably derived from walnut oil or metabolites thereof, and has a good application prospect.

The invention relates to application of a fingered citron extract in preparation of a medicine for treating metabolic syndrome, and belongs to the technical field of biological medicines. According to the fingered citron extract disclosed by the invention, the diversity of flora can be improved by regulating intestinal flora, and the relative abundance of beneficial bacteria Akkermansia is specifically increased, so that the metabolic syndrome induced by high fat diet is relieved. An embodiment verifies that the scheme of the invention not only can significantly inhibit weight gain of obese mice induced by high fat diet, improve glucose metabolism disorder (including reduction of fasting blood-glucose and improvement of oral glucose tolerance), relieve liver fat accumulation and pathological damage, reduce visceral fat accumulation and improve adipocyte hypertrophy, but also can significantly inhibit the weight gain of the obese mice induced by high fat diet and improve the glucose metabolism disorder (including reduction of fasting blood-glucose and improvement of oral glucose tolerance). And obesity-related metabolic hormone disorder can be effectively reversed, for example, the serum insulin level is improved, and the leptin level is reduced.

Provided herein is a method of reducing weight loss, increasing weight, increasing rate of weight gain, and / or treating failure to thrive in a patient, including administering to the patient vibrotactile stimulation for a duration and frequency sufficient to reduce weight loss, increase weight, increase rate of weight gain, and / or treat failure to thrive in the patient.

The application provides a use of perillaldehyde in preparation of a medicine for treating postpartum lack of lactation, and animal experiments show that perillaldehyde can effectively increase the lactation of postpartum lack of lactation female mice, significantly increase the litter weight growth rate of postpartum lack of lactation female mice, and improve the pathological state of mammary gland tissue of postpartum lack of lactation female mice. In addition, perillaldehyde has good safety and almost no side effects on the body. Therefore, the perillaldehyde described in the application can be used as an active ingredient and applied to preparation of a medicine for treating postpartum lack of lactation, thereby developing a new use of perillaldehyde and providing a new selection for preparation of a medicine for promoting lactation secretion and treating postpartum lack of lactation.

The invention relates to the technical field of poultry breeding, and discloses a poultry house environment self-adaptive regulation and control method and system. The method comprises the following steps: acquiring poultry physiological data through a sensor array to obtain a weight growth rate curve and a metabolic intensity fluctuation curve, and determining a physiological demand vector in combination with a preset feather development model; the poultry feather development degree is evaluated based on the physiological demand vector, a quantitative score is obtained, the relevance between the quantitative score and the physiological demand vector is analyzed, and a wind speed adjustment parameter is calculated based on the relevance; based on the wind speed adjusting parameters, generating an airflow distribution mode sequence, judging whether fluctuation abnormity exists or not, obtaining a wind speed control signal, transmitting the wind speed control signal to ventilation equipment, and adjusting wind speed intensity and ventilation frequency; collecting air quality feedback data in the poultry house in real time, inputting the data into the feather development model, determining a physiological demand vector adjustment value of the next period, and generating a breeding benefit evaluation report according to the adjustment value and the dynamic fluctuation data. The poultry breeding efficiency is improved.

The invention discloses a family breeding method of blue crab fast-growing strains, which is characterized by comprising the following steps: collecting full-cream crabs from different geographical areas, disinfecting, then adopting a series of measures to promote egg carrying, carrying out multi-stage intensified screening and breeding in different environments after membrane rupture of the eggs, and finally breeding the blue crab fast-growing strains. And calculating indexes such as a good rate, a weight growth rate and a body type growth rate, and setting a weight to determine a comprehensive score so as to select a good family. Constructing a family pairing scheme, separately breeding male and female, mating at a specific time, marking and continuing to breed seedlings. And repeating the breeding process of multiple generations. The method ensures genetic diversity, scientific breeding screening, quantitative evaluation index, targeted pairing and sustainable improvement of the blue crab variety, and provides an efficient breeding approach for the blue crab breeding industry.

The invention discloses application of MUSTN1 in promoting weight gain and intramuscular fat deposition of chickens, and belongs to the technical field of biological agriculture. According to the invention, the MUSTN1 gene and the encoding protein thereof are creatively applied, so that the synergistic improvement of chicken weight gain and intramuscular fat deposition is realized. The invention reveals for the first time that the over-expressed MUSTN1 gene can significantly increase the intramuscular fat (IMF) content while promoting the chicken weight increase, and effectively solves the long-standing technical bottleneck that the growth speed is negatively related to the meat flavor in commercial broiler chicken breeding. Test data show that the MUSTN1 overexpression enables the breast muscle IMF content of the Gushi chicken to be increased from 1.47% to 2.60%, the leg muscle IMF content of the Gushi chicken to be increased from 3.49% to 4.13%, and the weight of the Gushi chicken to be increased from 1507 g to 1707 g.

The invention discloses application of pyrrolotriazine compounds in preparation of medicines for preventing or treating obesity, and belongs to the technical field of medical chemistry. The invention provides application of pyrrolotriazine compounds or salts thereof in preparation of medicines for preventing or treating obesity in order to develop novel anti-obesity medicines which have the effects of reducing weight and have no side effects of appetite inhibition, muscle loss and the like. The compound or the salt thereof can obviously reduce the body weight of a mouse, slow down the body weight increase speed, reduce the contents of perirenal fat, epididymal fat and groin fat and reduce the fat content in the liver, has no influence on appetite, and provides a new choice for development and application of medicines for preventing and treating obesity.

The invention discloses a feed additive for increasing weight of fat pigs before slaughtering and a preparation method of the feed additive, and belongs to the technical field of feed additives. Comprising the following steps: taking hermetia illucens, locusta chinensis and silkworm chrysalis, removing impurities, sterilizing, cleaning, drying, putting into an oil press, extracting grease, centrifugally separating, removing impurities, and collecting a clean oil phase to obtain a material A; mixing a mulberry leaf extract, an aralia mandshurica root extract, an opuntia ficus-indica extract, a hippophae rhamnoides seed extract, a honeysuckle flower extract and deionized water to obtain a material B; mixing the material A with polyethylene glycol glycerol ricinoleate, and homogenizing to obtain a material C; and mixing the material B, the material C and Arabic gum, homogenizing, performing vacuum freeze drying, grinding and sieving to obtain the feed additive, and the weight gain growth of the fat pigs can be promoted through the synergistic effect of all the components.

The application belongs to the technical field of feed additives, and particularly relates to application of cytidine diphosphate ethanolamine in preparation of products for promoting animal growth or improving animal muscle performance. The application obtains the key metabolite cytidine diphosphate ethanolamine related to animal muscle performance through multi-omics joint analysis screening, the key metabolite cytidine diphosphate ethanolamine is derived from an animal body, is a key intermediate in phosphatidylethanolamine (PE) biosynthesis, and participates in CDP-Etn pathway regulation. The cytidine diphosphate ethanolamine can be applied in feed, feed additives or health products in a specific adding mode and dose, is suitable for various breeding animals such as rodents, poultry and mammals, and can significantly improve average daily feed intake, body weight growth rate, increase chest muscle weight, improve chest muscle rate and enhance grip strength.

The invention discloses a weight-reducing medicine with siraitia grosvenorii pomace water extract as an active ingredient and application of the weight-reducing medicine, and belongs to the technical field of biological medicine. The weight-reducing medicine with the siraitia grosvenorii pomace water extract as the active ingredient has the effects of reducing fat deposition, delaying weight gain and the like, and can effectively reduce animal abdominal fat deposition, relieve liver fatty lesion, slow down animal weight gain and reduce the fat content in animal bodies after being added into animal feed or daily ration; good application prospects are realized.

Provided herein is a method of reducing weight loss, increasing weight, increasing rate of weight gain, and / or treating failure to thrive in a patient, including administering to the patient vibrotactile stimulation for a duration and frequency sufficient to reduce weight loss, increase weight, increase rate of weight gain, and / or treat failure to thrive in the patient.