5 results about "Serum insulin" patented technology

This invention discloses the application of a high-N-acetylglycine-producing *Lactobacillus reuteri* strain in alleviating obesity-related metabolic diseases, belonging to the field of microbial technology. The *Lactobacillus reuteri* NO1 strain of this invention (…) Limosilactobacillus reuteri (NO1) possesses the ability to produce N-acetylglycine in vitro. This strain can inhibit weight gain in obese mice without affecting food intake; improve glucose tolerance in obese mice while reducing blood glucose, serum insulin, and insulin resistance index; regulate liver triglycerides in obese mice, and alleviate liver tissue damage. The *Lactobacillus reuteri* strain described in this invention has very broad application prospects for preparing anti-obesity pharmaceutical compositions and fermented foods.

The application discloses a preparation method of a human insulin purity standard substance, which comprises the following steps of raw material selection, qualitative identification, standard substance uniformity, stability test, value determination and uncertainty evaluation. The application uses commercially available high-purity human insulin as a raw material, and after purity analysis, qualitative identification, uniformity test and stability test, isotope-labeled Val, Leu and Phe are used as internal standards, and liquid chromatography-isotope dilution mass spectrometry is used for value determination, so that the interference and influence of possible isoleucine substitution leucine impurities, isomer impurities or other molecular weight protein impurities on the value determination result can be effectively excluded, and the value determination result is more accurate and reliable. The purity standard substance prepared by the application can be used for serum insulin standard substance quality value tracing, quality control of insulin measurement results in in-vitro diagnosis, related method confirmation and evaluation, and evaluation of repeatability, linearity and cross contamination rate of a closed light-emitting immune analyzer.

A baked dough food for consumption during fasting, methods of making the same, and methods of fasting that include consumption of the baked dough food are disclosed herein. The baked dough food includes a dry ingredient selected from the group consisting of almond flour, coconut flour, Psyllium husk powder, chia powder, flaxseed powder, and combinations thereof, baking soda, at least one of clarified butter, an oil, cacao butter, almond butter, peanut butter, unsweetened almond milk, or water, a sweetener, and a flavoring agent. The baked dough food does not produce an insulin spike or increased blood glucose level upon consumption.

The invention discloses high-quality highland barley bread with a low glycemic index as well as a preparation method and application of the high-quality highland barley bread. The invention provides highland barley composite flour. The highland barley composite flour comprises black highland barley flour, vital gluten, wheat flour and rye flour. The invention also provides highland barley bread which is prepared by taking the highland barley composite powder as a main raw material and utilizing an enzyme preparation and an intermediate fermentation process. The addition amount of the black highland barley powder in the highland barley composite powder reaches 60%, postprandial blood sugar can be effectively controlled, the glycemic index is 49.7, the specific volume is 4.03 mL / g, and the hardness is 605 g. Experiments prove that the low-GI bread can reduce the fasting blood glucose by 46.3% and the serum insulin by 33.0%, and is beneficial to maintaining the blood glucose level. The highland barley bread provided by the invention is helpful for expanding the consumption market of bread, and meets the requirements of people on diversified food consumption and nutrition and health.

The invention provides a method for evaluating the health of sows in the perinatal period based on metagenome sequences, a synthetic microbial community and application, and relates to the technical field of animal nutrition and biologication.The method comprises the steps of sample collection, index detection and judgment, microbial correlation analysis, screening platform construction and nutrient screening. According to the method, the problems that traditional diagnosis depends on highly invasive vein blood sampling and feedback lags behind are solved by excavating the relation between pregnant sow excrement microorganisms and serum insulin resistance and inflammatory factors. And early and accurate early warning of the metabolism health state of the sow can be realized by using fecal microorganisms. The constructed SynCom synthetic flora is not a general formula, but is a metabolic synergistic bacterium which is accurately locked based on big data and has the abundance significantly reduced in the perinatal period. Through directional supplement of the deleted members, excessive expansion of proinflammatory flora such as Prevotelasp.and the like can be effectively antagonized, and insulin resistance induced by inflammation is relieved from the source.