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Bionic gynecologic care solution and its preparation method

A nursing solution and bionic technology, applied in skin care preparations, pharmaceutical formulations, cosmetic preparations, etc., can solve the problems of accelerated vaginal aging, chronic erosion of vaginal mucosa, accelerated aging of vaginal mucosa, etc., and achieve the effect of accelerated aging

Active Publication Date: 2013-06-05
广西湾昊生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although chemical fungicides have no acute toxicity and acute damage to the vaginal mucosa, repeated use for a long time will cause chronic erosion and damage to the vaginal mucosa, affect physiological functions such as vaginal mucosal secretion, and accelerate the aging of the vaginal mucosa
In addition, repeated vaginal douching with fungicide aqueous solution or saline solution that is completely different in composition from vaginal secretions will also repeatedly destroy the microenvironment of the vagina, accelerate the aging of the vagina, cause vaginal dryness to come early, and affect the quality of sexual life

Method used

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  • Bionic gynecologic care solution and its preparation method
  • Bionic gynecologic care solution and its preparation method
  • Bionic gynecologic care solution and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Embodiment 1 bionic gynecological care solution

[0024] The bionic type gynecological care solution of the present embodiment is made up of following components:

[0025]

[0026] Add water to 1L.

[0027] The preparation method of the bionic type gynecological care solution of the present embodiment is as follows:

[0028] (1) Weigh each component according to the formula, dissolve other components except antibacterial peptide and medical hyaluronic acid with 800ml of pure water, and then add water to 1000ml; obtain artificial body fluid;

[0029] (2) Add 1.0 g of medical hyaluronic acid and stir evenly; adjust the pH to 3.3-4.4 to obtain artificial vaginal secretion;

[0030] (3) Add 0.2 g of antimicrobial peptide, stir evenly, and homogenize with a homogenizer to obtain the product.

Embodiment 2

[0031] Embodiment 2 bionic type gynecological care liquid

[0032] The bionic type gynecological care solution of the present embodiment is made up of following components:

[0033]

[0034] Add water to 1L.

[0035] The preparation method of the bionic type gynecological care solution of the present embodiment is as follows:

[0036] (1) Weigh each component according to the formula, dissolve other components except antibacterial peptide and medical hyaluronic acid with 800ml of pure water, and then add water to 1000ml; obtain artificial body fluid;

[0037] 1. Add 2.0g of medical hyaluronic acid and stir evenly; adjust the pH to 3.3-4.4 to obtain artificial vaginal secretion;

[0038] 2. Add 0.2 g of antimicrobial peptide, stir evenly, and homogenize with a homogenizer to obtain the product.

Embodiment 3

[0039] Embodiment 3 bionic type gynecological care liquid

[0040] The bionic type gynecological care solution of the present embodiment is made up of following components:

[0041]

[0042] Add water to 1L.

[0043] The preparation method of the bionic type gynecological care solution of the present embodiment is as follows:

[0044] (1) Weigh each component according to the formula, dissolve other components except antibacterial peptide and polyethylene glycol-400 with 800ml of pure water, and then add water to 1000ml; obtain artificial body fluid;

[0045] (2) Add polyethylene glycol-400 1.5g, stir evenly; adjust pH to 3.3-4.4 to obtain artificial vaginal secretion;

[0046] (3) Add 0.2 g of antimicrobial peptide, stir evenly, and homogenize with a homogenizer to obtain the product.

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Abstract

The invention discloses a bionic gynecologic care solution and its preparation method. The gynecologic care solution comprises antibacterial peptides and an artificial vaginal secretion solution having a pH value of 3.3-4.4, and the content of the antibacterial peptides in the artificial vaginal secretion solution is 0.1-10.0g / L; and the artificial vaginal secretion solution comprises an artificial body fluid and a thickening agent, and the content of the thickening agent in the artificial body fluid is 0.5-5.0g / L. The bionic gynecologic care solution adopts a bionic design, the artificial body fluid is treated as a solvent, is added with the thickening agent to adjust the viscosity, and is added with an acid or an alkali to adjust the pH value in order to obtain the artificial vaginal secretion solution similar to a human vaginal secretion solution in component, viscosity and pH, and the antibacterial peptides are selected as a as bactericide. The bionic gynecologic care solution does not have an abuse that a chemical bactericide chronically erodes the vaginal viscosity, does not excessively change the vaginal microenvironment or destroy the vaginal physiological balance, and can be used for intractable vaginitis treatment and daily vagina healthcare and disease prevention.

Description

technical field [0001] The invention belongs to the field of external disinfection drugs, in particular, the invention relates to a bionic gynecological care solution and a preparation method thereof. Background technique [0002] According to statistics, more than 75% of women have suffered from vaginitis at least once, many recurrent attacks are difficult to cure. The main bacteria that cause vaginitis are Candida albicans, Trichomonas, and Neisseria gonorrhoeae. [0003] The main treatment and preventive means to vaginitis at present is to use the solution of suitable bactericide to douche the vagina frequently, and severe cases will douche more than once a day. But at present all vaginal douches are mainly prepared with chemical bactericides and ultrapure water or saline. Although chemical fungicides have no acute toxicity and acute damage to the vaginal mucosa, repeated use for a long time will cause chronic erosion and damage to the vaginal mucosa, affect physiologic...

Claims

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Application Information

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IPC IPC(8): A61K8/64A61K8/73A61K8/81A61K8/86A61K38/00A61K47/26A61K47/04A61P31/02A61P15/02A61Q19/10
Inventor 陈松彬徐慧华
Owner 广西湾昊生物科技有限公司
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