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67 results about "Physiological stress" patented technology

Physiological stress is a particular form of stress which refers to the consequences of the failure of a human or animal body to respond appropriately to the load of a physical stimulus. It includes a state of alarm and adrenaline production, short-term resistance as a coping mechanism, and exhaustion.

Force application apparatus simulating human physiological stress of tissue bionic culture for tissue engineering

The invention discloses a force application device stimulating the human body physiological stress of bionic culture of a tissue in tissue engineering, which comprises a holder, wherein, a linear motor and a culture chamber are installed on the holder, a switch contact block and a tension and pressure transducer are installed at one end of the axle of the linear motor, a travel switch is installed on the axle housing of the motor axle, the tension and pressure transducer is connected with a connector through a coil spring and provided with a guiding axle which is inserted in the connector by passing through the coil spring and matched with the connector in a sliding way, the guiding axle has freedom of axial displacement in the connector, the culture chamber is provided with a device applying stress to culture tissue, the pole of the device applying stress to culture tissue extends out of the culture chamber and is connected with the connector and matched with the culture chamber in a sliding way. The force application device can stimulate the physiological stress and be used in the culture preparation of tissue engineering bone, gristle or tendon so as to realize the bionic culture of constructing tissue engineering bone, gristle or tendon.
Owner:ARMY MEDICAL UNIV

Intellectualized bionic cultivation apparatus for tissue engineering tissue

The invention discloses an intelligent biomimetic tissue cultivating device in tissue engineering, a gas-to-fluid and fluid-to-fluid exchanger is arranged between a tissue cultivating room and a fresh culture fluid storage bottle, the tissue cultivating room is connected with the gas-to-fluid and fluid-to-fluid exchanger through a circular pipeline, the fresh culture fluid storage bottle is communicated with the gas-to-fluid and fluid-to-fluid exchanger through another circular pipeline, a telescopic pump that is driven by a stepping motor is respectively arranged on each circular pipeline, the gas-to-fluid and fluid-to-fluid exchanger is communicated with O2/CO2/N2 sources through a gas transmitting pipe with a throttle, a forcing device that is driven by the stepping motor and simulates physiological stress of human beings is connected with a device used for exerting stress on a cultivated tissue of the tissue cultivating room, and a programmable logic controller is arranged for implementing intelligent control to the cultivation process. The intelligent biomimetic tissue cultivating device not only can provide the in vitro culture environment that is used for the in vitro tissue cultivation in tissue engineering and similar to the in vivo environment and truly realize biomimetic cultivation, but also can realize industrial production with intelligent control.
Owner:THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
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