The invention discloses a chromatographic
data optimization processing method for a liquid chromatograph, and relates to the technical field, and the method comprises the following steps: collecting an original
signal flow, carrying out preliminary
peak detection, and generating an original peak
list; extracting
modal exclusive characteristics of each chromatographic peak; converting the
modal exclusive features into a unified multi-dimensional
semantic feature vector; calculating a time interval weight, and calculating a semantic relevancy weight based on the multi-dimensional
semantic feature vector; correcting the time interval weight, generating a network edge weight, and constructing a peak correlation topology network by taking the multi-dimensional
semantic feature vector as a node; identifying node clusters connected with high edge weights, and aggregating the node clusters into candidate compound entities; tracking a node
signal intensity change track, and adding a conflict mark; conflict resolution arbitration is carried out on the candidate compound entities with the added conflict marks, dominant
detector evidence is output, and an analysis report is generated. According to the method, the problems of poor
data collaboration of multiple detectors, inaccurate peak identification and association and isolated
data processing flow are effectively solved.