The invention relates to a medicinal preparation for treating an Alzheimer disease and an application of the medicinal preparation. The medicinal preparation comprises coptis, perilla stems, epimedium, semen cuscutae, black soya beans, holly leaves, obcordateleaf raspberry fruits, burdock, wild rice shoots, orchis, liquorice, rhizoma acori graminei, polygala tenuifolia, rhodiola rosea, root of kudzu vine, eupatorium, piper cubeba, sophora flowers, Chuanxiong rhizome and borneol. The traditional Chinese medicine formula treats the Alzheimer disease by a qi regulating and blood circulation activating method. The medicinal preparation in the traditional Chinese medicine formula is low in therapeutic side effect and prepared from traditional Chinese medicines serving as raw materials through the scientific formula and repeated verification and preparation of clinical tests, conforms to the theory of traditional Chinese medicine, improves body immunity, has multiple action targets, is high in effective rate and suitable for clinical popularization and application, and has high development values.