ACLR afterbrain limb integrated precise rehabilitation method and system based on electroacupuncture and PNF collaboration

Abstract

The invention discloses an electroacupuncture and PNF collaborative ACLR afterbrain limb integrated precise rehabilitation method and system, and relates to the technical field of clinical medicine rehabilitation treatment, and the method comprises the steps: S1, baseline function and iconography evaluation; s2, preparing center modulation; s3, peripheral motion driving is carried out; s4, quantitative acquisition and response evaluation; s5, performing parameter adjustment and periodic execution; according to the invention, quantified physiological and functional indexes are embedded as a closed-loop adjustment basis, so that the electroacupuncture parameters and PNF strength of each treatment can be optimized in a data-driven manner. Through periodical evaluation of clinical knee joint function scores, balance parameters, SEMG and central function activation and adjustment and intervention according to preset rules, the method realizes transformation from empirical rehabilitation to evidence-driven and individualized rehabilitation. According to the closed-loop design, benefits of individuals on intervention can be amplified, and adverse reactions or overload risks can be recognized in real time, so that the possibility of treatment side effects or function degradation is reduced.

Description

Technical Field

[0001] This invention relates to the field of clinical medical rehabilitation technology, specifically to a precise brain-limb integrated rehabilitation method and system for ACLR that combines electroacupuncture and PNF. Background Technology

[0002] Anterior cruciate ligament (ACLR) reconstruction is a core surgical procedure for treating ACL rupture and restoring knee joint stability. However, postoperative knee joint function remodeling and motor function recovery rely on scientific and systematic rehabilitation interventions. Clinical practice shows that ACLR not only presents problems such as insufficient peripheral joint stability, decreased muscle strength, and proprioceptive impairment, but also involves delayed remodeling of the central motor network, leading to impaired brain-limb coordinated control. Improper rehabilitation can easily cause long-term complications such as chronic pain and osteoarthritis, and may even prevent the recovery of preoperative motor function levels. Therefore, effective ACLR rehabilitation needs to take into account both central nervous system modulation and peripheral motor function training to achieve integrated brain-limb functional remodeling.

[0003] Currently, although various intervention programs have been developed in the field of ACLR post-rehabilitation, such as simple PNF (proprioceptive neuromuscular facilitation) training, conventional electroacupuncture, and basic muscle strength training, existing technologies still have many key shortcomings and are difficult to meet the needs of precise and integrated rehabilitation.

[0004] For example, interventions lack synergy, and there is a disconnect between central and peripheral regulation. Some treatments, while using electroacupuncture or PNF techniques alone, fail to achieve scientific synergy between the two. On the one hand, although electroacupuncture alone can regulate nerve function, the lack of peripheral motor drive makes it difficult to translate the central modulation effect into actual improvement in motor ability; on the other hand, the core manipulation traction stimulation and resistance training patterns of PNF are prone to triggering postoperative pain reactions, forcing the treatment intensity to fall below the optimal threshold.

[0005] Studies have found that electroacupuncture can compensate for the aforementioned limitations of prophylactic nerve block (PNF). By stimulating acupoints such as Zusanli (ST36), it can unblock meridians, improve local blood circulation, accelerate the metabolism of inflammatory substances, and reduce patient pain, thus creating favorable conditions for PNF training. Even though a few studies have attempted to combine electroacupuncture with PNF training, the temporal coupling window and parameter matching relationship between electroacupuncture and PNF training have not been clearly defined, making it impossible to fully realize the synergistic effect.

[0006] In response to this, this application proposes a precise rehabilitation method and system for the brain and limbs after ACLR, which combines electroacupuncture and PNF, to solve the above problems. Summary of the Invention

[0007] The purpose of this invention is to provide a precise, integrated brain-limb rehabilitation method and system for ACLR that combines electroacupuncture and PNF, addressing the lack of synergy in existing intervention methods and the disconnect between central and peripheral regulation. While some solutions utilize electroacupuncture or PNF techniques individually, they fail to achieve the scientific synergy between the two.

[0008] To achieve the above objectives, the present invention provides the following technical solution:

[0009] A precise, integrated brain-limb rehabilitation method combining electroacupuncture and PNF for ACLR includes:

[0010] S1. Baseline Functional and Imaging Assessment Steps: Clinical and functional baseline assessments are performed on subjects to obtain their initial brain-limb functional status, including Lysholm knee function score, balance / proprioception index, surface electromyography baseline, and task-based functional magnetic resonance imaging data.

[0011] Initial functional assessments and individualized rehabilitation initiation parameters are obtained from baseline data;

[0012] S2. Central modulation preparation steps: Based on the subject's initial brain-limb functional state, electroacupuncture stimulation is applied to the subject to directionally modulate the central motor network and obtain a modulated central activation state; the electroacupuncture stimulation includes needling specific acupoints and connecting the electroacupuncture output to apply alternating dense and sparse wave stimulation to produce a perceptible needling sensation and a tolerable current intensity.

[0013] S3, Peripheral motor drive steps: By implementing PNF pattern training for the affected limb, the modulated central activation state is coupled with peripheral receptor input to obtain an enhanced sensorimotor integration response;

[0014] S4. Quantitative Acquisition and Response Assessment Steps: Based on the enhanced sensory-motor integration response, collect and analyze clinical knee joint function scores, surface electromyography, balance / proprioceptive indices, and task-state functional magnetic resonance imaging data to quantify the changes in peripheral electromyographic recruitment, proprioceptive control, and central function caused by training, and obtain quantitative response indices.

[0015] S5. Parameter Adjustment and Periodic Execution Steps: Based on the quantitative response indicators, make targeted adjustments to the electroacupuncture parameters and PNF training intensity / mode, and repeat steps S2 to S4. Continue to implement the periodic and adjustable plan until the predetermined rehabilitation endpoint is reached or the clinical improvement standard compared with the baseline is achieved, thereby obtaining the brain-limb function remodeling and motor ability recovery effect of the subject.

[0016] Further, the electroacupuncture stimulation described in step S2 includes: needling at Fengshi, Fumian, Zusanli, Shangjuxu, Fenglong, Xuanzhong, Diji and Sanyinjiao, using 0.3 mm × 40 mm filiform needles inserted perpendicularly for 20 mm, using the tonifying, neutralizing and reducing technique to obtain Qi, then connecting the filiform needles to the electroacupuncture device, connecting the electrodes in opposite pairs and outputting a sparse-dense wave (2 Hz / 100 Hz), with the current intensity at 2-5 mA to the patient's tolerance, stimulating for 20-30 min, once a day, 5 times a week.

[0017] Further, the PNF pattern training described in step S3 includes: the subject lies supine with the knee joint in the range of 0 to 30 degrees and performs static or dynamic contraction training in the D1 extension (D1E) and D2 extension (D2E) patterns. The contraction patterns include hold-relaxation, contraction-relaxation-rhythmic stability, rhythmic initiation, repetitive contraction and eccentric / concentric conversion. The training intensity is 10 times / set, 3 sets / session, 1 time / day, 5 times / week, and the subject's subjective physical sensation (RPE) is maintained in the range of approximately 14 to 15.

[0018] Furthermore, the quantitative acquisition and analysis described in step S4 includes:

[0019] (a) Using the Pro-Kin balance test system, the area and length ratio of the closed eyes / open eyes were measured while standing on one leg with eyes closed / open, and a multi-axis body assessment was performed to obtain the mean trajectory error (ATE) and the mean load difference rate (AFV).

[0020] (b) Surface electromyography was used to acquire data from the target muscle groups (including rectus femoris, vastus medialis, vastus lateralis, biceps femoris, and semitendinosus) at a sampling frequency of approximately 2048 Hz. The RMS of normalized long peak electromyography was recorded to reflect the degree of muscle recruitment and synchronization.

[0021] In addition, task-based functional magnetic resonance imaging (fMRI) was performed using a “resting 30s – movement 30s” block design to assess changes in brain-limb functional connectivity.

[0022] It also includes clinical follow-up assessments using the Lysholm knee score before and after treatment, as one of the clinical endpoints for judging the overall rehabilitation effect.

[0023] Furthermore, the periodization described in step S5 includes: using electroacupuncture and PNF in parallel or sequential combination as a treatment course, 5 times a week for 4 to 8 consecutive weeks, and retesting the baseline assessment items at the end of each treatment course to determine whether the predetermined rehabilitation endpoint has been reached.

[0024] Furthermore, the PNF training includes performing repetitive, patterned movements in a supine position with a specified knee joint range of motion and contraction pattern;

[0025] The PNF training is initiated immediately after the start of electroacupuncture stimulation or within 5 minutes after the end of electroacupuncture stimulation. It is used to achieve temporal coupling between central modulation and peripheral motor input, thereby enhancing the sensory-motor integration effect.

[0026] Furthermore, the quantitative response indicators described in step S4 are used to form an actionable adjustment basis: when the RMS, ATE or AFV, task-based functional magnetic resonance imaging data, and Lysholm knee score show improvement compared to the baseline, the training load should be maintained or slightly reduced; when no improvement or deterioration is observed, the electroacupuncture intensity or PNF load should be appropriately reduced and reassessed until acceptable functional improvement is achieved.

[0027] A precise, integrated brain-limb rehabilitation system combining electroacupuncture and PNF for ACLR includes:

[0028] Baseline Functional and Imaging Assessment Module: Used to conduct clinical and functional baseline assessments of subjects to obtain their initial brain-limb functional status;

[0029] Central modulation preparation module: used to apply electroacupuncture stimulation to the subject based on the subject's initial brain-limb functional state in order to perform targeted modulation of the central motor network and obtain a modulated central activation state;

[0030] Peripheral motor drive module: used to couple the modulated central activation state with peripheral receptor input by implementing PNF pattern training for the affected limb, thereby obtaining an enhanced sensorimotor integration response;

[0031] Quantitative Acquisition and Response Assessment Module: Based on the enhanced sensory-motor integration response, this module collects and analyzes clinical knee joint function scores, surface electromyography, balance / proprioceptive indices, Lysholm knee score, and task-based functional magnetic resonance imaging data to quantify changes in peripheral electromyographic recruitment, proprioceptive control, and central function induced by training, and obtains quantitative response indices.

[0032] The parameter adjustment and periodic execution module is used to make targeted adjustments to the electroacupuncture parameters and PNF training intensity / mode according to the quantitative response index, and to repeatedly execute the central modulation preparation module to the quantitative acquisition and response evaluation module in a periodic and adjustable manner until the predetermined rehabilitation endpoint is reached or the clinical improvement standard compared with the baseline is reached, thereby obtaining the brain-limb function remodeling and motor ability recovery effect of the subject.

[0033] Compared with existing technologies, this invention provides a precise, integrated brain-limb rehabilitation method and system for ACLR synergistic electroacupuncture and PNF. This method embeds quantified physiological and functional indicators as a closed-loop adjustment basis, allowing for data-driven optimization of electroacupuncture parameters and PNF dosage for each treatment session. By periodically assessing clinical knee joint function scores, balance parameters, SEMG (Self-Regulating Mental Health), and central nervous system activation, and adjusting interventions according to preset rules, the method achieves a shift from "experience-based" rehabilitation to "evidence-driven, individualized" rehabilitation. This closed-loop design amplifies individual benefits from intervention (factor-tailored) and enables immediate identification of adverse reactions or overload risks, reducing the possibility of treatment side effects or functional decline. Therefore, this invention not only improves the predictability of short-term efficacy but also helps maintain long-term functional improvement and reduces resource waste. Attached Figure Description

[0034] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in this invention. For those skilled in the art, other drawings can be obtained based on these drawings.

[0035] Figure 1 A flowchart of a precise brain-limb integrated rehabilitation method for ACLR with electroacupuncture and PNF synergy provided in an embodiment of the present invention;

[0036] Figure 2 A block diagram of an integrated brain-limb precision rehabilitation system for ACLR, combining electroacupuncture and PNF, is provided for an embodiment of the present invention. Detailed Implementation

[0037] To enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below with reference to the accompanying drawings.

[0038] As attached Figure 1 As shown:

[0039] Example 1:

[0040] A precise, integrated brain-limb rehabilitation method combining electroacupuncture and PNF for ACLR includes:

[0041] S1. Conduct clinical and functional baseline assessments on the subjects to obtain their initial brain-limb functional status;

[0042] Specifically, the subjects underwent Lysholm knee score assessment, static / dynamic balance and proprioception tests (such as standing on one leg with eyes closed, platform trajectory measurement), baseline acquisition of surface electromyography (sEMG) (target muscle groups were placed with standard electrodes and MVC calibration was performed), and, if necessary, task-based functional magnetic resonance imaging or other imaging examinations.

[0043] Furthermore, the questionnaires were completed by patients according to a predetermined format and checked by trained assessors; sEMG sampling frequency and filtering were performed according to laboratory SOPs, and %MVC was obtained through MVC normalization; the balancing platform collected indicators such as trajectory and area according to the manufacturer's technical specifications; and imaging was collected according to routine task design and functional connectivity or activation mapping analysis was performed.

[0044] S2. Based on the subject's initial brain-limb functional state, electroacupuncture stimulation is applied to the subject to directionally modulate the central motor network and obtain a modulated central activation state.

[0045] Specifically, the electroacupuncture stimulation in step S2 includes: needling at Fengshi, Fumian, Zusanli, Shangjuxu, Fenglong, Xuanzhong, Diji and Sanyinjiao, using 0.3 mm × 40 mm filiform needles inserted perpendicularly for 20 mm, using the tonifying, neutralizing and reducing technique to obtain Qi, then connecting the filiform needles to the electroacupuncture device, connecting the electrodes in opposite pairs and outputting with a sparse-dense wave (2 Hz / 100 Hz), the current intensity is 3 mA to the patient's tolerance, the stimulation lasts for 30 min, once a day, 5 times a week;

[0046] Furthermore, acupuncture points or meridian points corresponding to the knee joint muscles and related sensory pathways are selected for acupuncture. An electroacupuncture device is used to output sparse / complex waveforms (commonly alternating between low and high frequencies) to activate different types of nerve fibers and produce a controllable central modulation effect. The procedure includes obtaining qi, connecting the electroacupuncture needle, setting the output waveform, intensity, and duration, and adjusting them individually according to the patient's tolerance.

[0047] Key parameters and criteria: Needle specifications and insertion depth should prioritize clinical safety; current intensity should be based on patient tolerance and recorded; stimulation waveforms and time windows should be pre-set with PNF timing to achieve temporal coupling. Whether central modulation achieves the expected results can be verified through short-term EEG, task-oriented activation, or subjective / objective functional performance (such as immediate sEMG changes).

[0048] S3. By implementing PNF pattern training for the affected limb, the modulated central activation state is coupled with peripheral receptor input to obtain an enhanced sensorimotor integration response.

[0049] Specifically, the PNF pattern training described in step S3 includes: the subject lies supine with the knee joint in the range of 0 to 30 degrees and performs static or dynamic contraction training in the D1 extension (D1E) and D2 extension (D2E) patterns. The contraction patterns include hold-relaxation, contraction-relaxation-rhythmic stability, rhythmic initiation, repetitive contraction and eccentric / concentric conversion. The training intensity is 10 times / set, 3 sets / session, 1 time / day, 5 times / week, and the subject's subjective physical sensation (RPE) is maintained at 14-15.

[0050] Furthermore, PNF patterns related to knee joint function recovery (such as extension / flexion combinations of D1 and D2 patterns) are employed to control joint angle, contraction type (isometric, concentric, eccentric, repetitive contraction, hold-relaxation, etc.), number of repetitions and sets, and intensity and frequency are set according to the postoperative allowable range and patient tolerance. The execution time of PNF should overlap with or immediately follow the time window of electroacupuncture stimulation to achieve temporal coupling of central-peripheral input.

[0051] RPE, joint angle limitation, sets and intervals were used as training dose control; sEMG and functional test data were collected in real time or periodically to determine the recruitment quality and improvement in motor coordination.

[0052] S4. Based on the enhanced sensorimotor integration response, collect and analyze clinical knee joint function scores, surface electromyography, balance / proprioceptive indices and task-state functional magnetic resonance imaging data to quantify the changes in peripheral electromyography recruitment, proprioceptive control and central function caused by training, and obtain quantitative response indices.

[0053] Specifically, quantitative data collection and analysis include:

[0054] (a) Using the Pro-Kin balance test system, the area and length ratio of the closed eyes / open eyes were measured while standing on one leg with eyes closed / open, and a multi-axis body assessment was performed to obtain the mean trajectory error (ATE) and the mean load difference rate (AFV).

[0055] (b) Surface electromyography was used to acquire data from the target muscle groups (including rectus femoris, vastus medialis, vastus lateralis, biceps femoris, and semitendinosus) at a sampling frequency of approximately 2048 Hz. The RMS of normalized long peak electromyography was recorded to reflect the degree of muscle recruitment and synchronization.

[0056] (c) Perform task-based functional magnetic resonance imaging (fMRI) with a “resting 30s-motor 30s” block design to assess changes in brain-limb functional connectivity.

[0057] (d) Clinical knee function scoring, constructing the Lysholm knee scoring system.

[0058] Furthermore, Pro-Kin balance test evaluation: The Italian Tecnobody Pro-Kin 254 balance test system was used to quantitatively detect proprioception and balance function.

[0059] The environment should be kept relatively quiet during the test. (1) Static stability assessment: The patient stands upright with both hands on the front support bar and stands barefoot in the standard standing posture of the affected foot: the medial malleolus of the foot passes through the red horizontal line (3cm below the horizontal axis of A3A7), the second toenail points to A1, and the midpoint of the heel points to A5. The chest position sensor is placed and zeroed. The balance board is set to static, and the patient stands on one foot with eyes open (the screen is turned towards the tester, and the patient looks straight ahead at a fixed point 1.5m away) and eyes closed for 30 seconds. After the test, the system automatically calculates and records the ratio of the closed / open eye area and length. The average value is taken after 3 tests. The normal range is between 110 and 250, which is considered to be a reasonable level of visual involvement in balance stability. A value less than 110 is considered to be a visual impairment of balance ability, and a value greater than 250 is considered to be a high level of visual involvement, indicating a lack of proprioception.

[0060] (2) Multiaxial Proprioceptive Assessment: The patient's standing position is the same as above, with the chest sensor placed and zeroed. The balance board is set to dynamic, the stability sensitivity parameter is set to "1", the assessment time is 60s, and the motion dimension is set to 5°~10°. The patient is instructed to control the affected foot from the red starting position, following the arrow, and try to complete 3 circular movements along the blue curve trajectory. After the test, the system automatically calculates and records the average track error (ATE) and average freeweight variance (AFV). The average value is taken from 3 tests. ATE shows the deviation between the trajectory of the center of gravity projection point and the given trajectory, reflecting the knee joint's control over body movement. AFV reflects the knee joint's control over weight-bearing force. The smaller the values ​​of both, the better the proprioceptive function of the affected knee.

[0061] Furthermore, the task-oriented functional magnetic resonance imaging (fMRI) data acquisition method is as follows: The patient lies calmly on the machine and performs bilateral knee flexion and extension exercises, with knee flexion and extension angles ranging from 0 to 45°. The hip and the area below the ankle of the affected limb are secured with straps to ensure movement only at the knee joint, preventing slight head movement caused by lower limb movement. The rest of the body remains relaxed and still. A chunked design is used: first, a 30-second rest period, followed by 30 seconds of continuous movement (equivalent to 10 brain images), then alternating between rest and movement 6 times. Each scan lasts 6 minutes. A speaker is used to remind the patient to begin the task and perform knee flexion and extension exercises and rest periods. Before the scan, the subject practices to ensure stable and accurate completion of the movement task.

[0062] Task-based functional magnetic resonance imaging (fMRI) data were analyzed using voxel-based functional imaging to assess changes in oxygen-dependent level (BOLD) signal activation intensity, activation range, and functional connectivity between brain regions related to balance and motor control, such as the primary motor area (M1), supplementary motor area (SMA), primary sensory area (S1), anterior lobe, lingual gyrus, and cerebellum. This quantified the degree of remodeling of the central motor network. By comparing the data with baseline contemporaneous task-based fMRI data, the specific regulatory effect of this protocol on the brain-limb linkage functional network was clarified. If no improvement or deterioration was observed, the intensity of electroacupuncture or PNF load was appropriately reduced and the assessment was repeated until acceptable functional improvement was achieved.

[0063] Furthermore, a clinical knee function scoring system was developed using the Lysholm Knee Rating Scale, which focuses on assessing subjective knee instability after ACLR (Advanced Knee Rhinoplasty). This scale demonstrates good reliability and validity. It covers eight sub-sections, including: squatting and standing, climbing stairs, weight-bearing capacity, degree of limping during walking, joint instability and locking, and degree of pain and swelling. The total score is 100 points, with 95 points or above considered excellent, 84 points or above good, 65 points or above satisfactory, and below 65 points considered poor.

[0064] Furthermore, clinical knee joint function scores, surface electromyography, balance / proprioceptive indices, and task-oriented functional magnetic resonance imaging data are collected at predetermined frequencies during or after training.

[0065] Set time points (e.g., weekly, mid-course assessments), sampling setups, and data storage schemes; establish primary and secondary response indicators and their improvement / deterioration criteria.

[0066] The quantitative response indicators are used to form actionable adjustment criteria: when the RMS, ATE or AFV, task-based functional magnetic resonance imaging data, and Lysholm knee score show improvement compared to baseline, the training load should be maintained or reduced.

[0067] S5. Adjust the electroacupuncture parameters and PNF training intensity / mode in a targeted manner according to the quantitative response index, and repeat steps S2 to S4. Continue to implement the program in a periodic and adjustable manner until the predetermined rehabilitation endpoint is reached or the clinical improvement standard compared with the baseline is achieved, thereby obtaining the brain-limb function remodeling and motor ability recovery effect of the subject.

[0068] Specifically, the periodization includes: a course of treatment consisting of electroacupuncture and PNF in parallel or sequential combination, 5 times a week for 4 to 8 consecutive weeks, and at the end of each course of treatment, the baseline assessment items are retested to determine whether the predetermined rehabilitation endpoint has been reached.

[0069] The PNF training includes performing repetitive, patterned movements in a supine position with a specified knee joint range of motion and contraction pattern;

[0070] The PNF training is initiated immediately after the start of electroacupuncture stimulation or within 5 minutes after the end of electroacupuncture stimulation. It is used to achieve temporal coupling between central modulation and peripheral motor input, thereby enhancing the sensory-motor integration effect.

[0071] Furthermore, by setting clear adjustment rules (e.g., maintaining or slightly adjusting the training load when continuous assessments show a positive trend; reducing intensity / increasing recovery periods and reassessing when stagnation or deterioration occurs), and defining treatment duration, frequency, and retest points (e.g., retesting every 4 weeks or at the end of each treatment course), different dosage designs, including short-term intensive phases and long-term consolidation phases, can be periodically implemented, and parameter ranges and training focuses can be switched according to the recovery stage (early / mid / chronic phase).

[0072] Adjustments should be based on predefined response thresholds and safety monitoring (including indicators of pain, fatigue, and complications); the treatment endpoint is a composite endpoint including functional scores reaching predetermined improvement standards, stable improvement in imaging or physiological indicators, or improvement in subjective quality of life. This constitutes the execution end of a closed-loop treatment, ensuring individualized, dynamically adapted, and maximized efficacy of the intervention, while also considering safety and long-term maintenance.

[0073] As shown above, this method couples controllable electroacupuncture central modulation with task-oriented peripheral PNF stimulation within a defined time window: highly relevant peripheral sensory-motor inputs are applied immediately or briefly within the electroacupuncture-induced central plasticity window, thereby enabling transient neural network activation to be more effectively converted into persistent motor pattern reconstruction. Compared to isolated electroacupuncture or simple external rehabilitation training, this method improves the efficiency of the conversion from "central plasticity state" to "peripheral functional improvement" through time-synchronized stimulus-training coupling, shortens the initiation period of functional remodeling, and enhances the quality of remodeling. This mechanism is not only based on the application of fundamental principles of neural plasticity (i.e., training applied during enhanced excitation or plasticity gating periods is more likely to produce lasting changes), but also achieves a balance between reproducibility and safety in clinical implementation through a defined time window and adjustable parameters.

[0074] As shown above, most traditional rehabilitation programs focus on peripheral muscle strength recovery or single training modalities. This method, however, adopts a "brain-limb integration" concept to coordinate the reconstruction of the central nervous system and the peripheral executive system: electroacupuncture modulates the central nervous system to improve sensory processing and motor intention generation; proprioceptive neural pathways (PNF) provide highly relevant peripheral inputs to train executive pathways and proprioceptive loops; and quantitative assessment enables real-time monitoring and optimization of their synergy. This systematic strategy allows for the synchronous regulation of sensory inputs (such as proprioception and plantar sensation) and executive outputs (muscle strength and coordination), thereby more thoroughly reconstructing the functional closed loop, reducing functional compensation patterns, and improving the naturalness and stability of motor control. This effect is significant for postoperative functional recovery, reducing the risk of re-injury, and promoting the long-term return of patients' motor abilities.

[0075] Example 2:

[0076] like Figure 2 As shown, in one embodiment, the present invention also provides an integrated precision rehabilitation system for the posterior brain and limbs after ACLR, combining electroacupuncture and PNF, comprising:

[0077] Baseline Functional and Imaging Assessment Module: Used to conduct clinical and functional baseline assessments of subjects to obtain their initial brain-limb functional status;

[0078] Central modulation preparation module: used to apply electroacupuncture stimulation to the subject based on the subject's initial brain-limb functional state in order to perform targeted modulation of the central motor network and obtain a modulated central activation state;

[0079] Peripheral motor drive module: used to couple the modulated central activation state with peripheral receptor input by implementing PNF pattern training for the affected limb, thereby obtaining an enhanced sensorimotor integration response;

[0080] Quantitative Acquisition and Response Assessment Module: Based on the enhanced sensory-motor integration response, this module collects and analyzes clinical knee joint function scores, surface electromyography, balance / proprioceptive indices, and task-based functional magnetic resonance imaging data to quantify changes in peripheral electromyographic recruitment, proprioceptive control, and central function caused by training, and obtains quantitative response indices.

[0081] The parameter adjustment and periodic execution module is used to make targeted adjustments to the electroacupuncture parameters and PNF training intensity / mode according to the quantitative response index, and to repeatedly execute the central modulation preparation module to the quantitative acquisition and response evaluation module in a periodic and adjustable manner until the predetermined rehabilitation endpoint is reached or the clinical improvement standard compared with the baseline is reached, thereby obtaining the brain-limb function remodeling and motor ability recovery effect of the subject.

[0082] The beneficial effects of the same electroacupuncture and PNF combined ACLR posterior brain-limb integrated precision rehabilitation method are not elaborated here.

[0083] The foregoing has only described certain exemplary embodiments of the present invention by way of illustration. Undoubtedly, those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the foregoing drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. An ACLR post-brain limb integration precision rehabilitation method of electric acupuncture and PNF coordination, characterized in that, Comprising: S1, performing clinical and functional baseline assessment to obtain initial brain-limb function status of the subject; S2, based on the initial brain-limb function status of the subject, performing electroacupuncture stimulation to the subject to modulate the central motor network and obtain modulated central activation status; S3, performing PNF mode training on the affected limb to couple the modulated central activation status with peripheral receptor input to obtain enhanced sensorimotor integration response; S4, based on the enhanced sensorimotor integration response, collecting and analyzing clinical knee function score, surface electromyography, balance / prosthetic sense index and task-state functional magnetic resonance data to quantify peripheral muscle recruitment, prosthetic sense control and central function changes caused by training, and obtain quantitative response index; S5, according to the quantitative response index, adjusting the electroacupuncture parameters and PNF training intensity / mode, and repeating steps S2 to S4 to implement a periodic and adjustable program until a predetermined rehabilitation endpoint is reached or a clinical improvement standard compared with the baseline is reached, thereby obtaining brain-limb function remodeling and motor ability recovery effect of the subject.

2. The method according to claim 1, wherein the method is characterized in that, In step S1, the initial brain-limb function status of the subject includes knee function score, balance / prosthetic sense index, surface electromyography baseline and task-state functional magnetic resonance imaging data.

3. The method according to claim 1, wherein the method is characterized in that, In step S2, the electroacupuncture stimulation includes: acupuncture at Fengsi, Fumai, Foot Three Li, Shangjuxu, Fenglong, Xuanzhong, Diji and Sanyinjiao, using 0.3 mm x 40 mm needle to straighten 20 mm, using supplementary and draining methods to get qi, then connecting the needle to the electroacupuncture instrument, pairing the electrodes and outputting with sparse and dense waves, the current intensity is 2-5 mA tolerated by the patient, the stimulation lasts for 20-30 minutes, once a day, 5 times a week.

4. The method according to claim 1, wherein the method is characterized in that, In step S3, the PNF mode training includes: the subject takes supine position, the knee joint is in the range of 0-30° to perform static or dynamic contraction training of D1 extension and D2 extension mode, the contraction mode includes hold-relax, contraction-relax-rhythmic stability, rhythmic start, repeated contraction and centrifugal / centripetal conversion, the training intensity is 10 times / group, 3 groups / time, 1 time / day, 5 times / week, and the subject's subjective physical feeling RPE is maintained in the range of 14-15.

5. The method according to claim 1, wherein the method is characterized in that, In step S4, the quantitative collection and analysis includes: Using Pro-Kin balance test system to measure the area and length ratio of closed eyes / open eyes single leg standing in static state, and performing multi-axis prosthetic evaluation to obtain average trajectory error ATE and average weight difference rate AFV; Using surface electromyography to collect target muscle groups, the sampling frequency is about 2048 Hz, and the RMS of normalized long peak electromyography is recorded to reflect muscle recruitment and synchronization degree; Task-state functional magnetic resonance is performed to assess the functional connectivity changes of brain-limb linkage according to the rest 30s-movement 30s block design; Lysholm knee score table is used for clinical follow-up evaluation before and after treatment as one of the clinical endpoints for judging the overall effect of rehabilitation.

6. The method according to claim 1, wherein the method is characterized in that, The periodicization in step S5 includes: combination of electroacupuncture and PNF in parallel or sequentially in a treatment course, 5 times per week, for 4-8 weeks, and retesting the baseline evaluation items at the end of each treatment course to determine whether the predetermined rehabilitation endpoint is reached.

7. The method according to claim 1, wherein the method is a method of electroacupuncture and PNF coordinated ACLR post-brain limb integration precise rehabilitation. The PNF training includes performing repetitive patterned movements with specified knee joint movement angles and contraction patterns in supine position; The PNF training is initiated immediately after the start of electroacupuncture or within 5 minutes after the end of electroacupuncture, for achieving temporal coupling of central modulation and peripheral motor input, thereby enhancing the sensory-motor integration effect.

8. The method according to claim 5, wherein the method is characterized in that, The quantitative response indicators in step S4 are used to form the basis for operational adjustment: When the RMS, ATE or AFV, task-state functional magnetic resonance data, Lysholm knee score show improvement compared with baseline, the training load is preferably maintained or reduced; When no improvement or deterioration is seen, the electroacupuncture intensity or PNF load is appropriately reduced and re-evaluated until an acceptable functional improvement is obtained.

9. An electric needle and PNF coordinated ACLR post-brain limb integration precise rehabilitation system, characterized in that, Comprise: Baseline functional and imaging evaluation module: for clinical and functional baseline evaluation of the subject, to obtain the initial brain-limb function state of the subject; Central modulation preparation module: for implementing electroacupuncture stimulation on the subject based on the initial brain-limb function state of the subject, to perform directional modulation on the central motor network and obtain a modulated central activation state; Peripheral motor drive module: for implementing PNF pattern training for the affected limb, to couple the modulated central activation state with peripheral receptor input, and obtain an enhanced sensory-motor integration response; Quantitative acquisition and response evaluation module: for acquiring and analyzing clinical knee function scores, surface electromyography, balance / prosthetic sensation indicators and task-state functional magnetic resonance data based on the enhanced sensory-motor integration response, to quantify the peripheral muscle recruitment, prosthetic sensation control and central function changes caused by training, and obtain quantitative response indicators; Parameter adjustment and periodicization execution module: for targeted adjustment of electroacupuncture parameters and PNF training intensity / pattern according to the quantitative response indicators, and repeated execution of the central modulation preparation module to the quantitative acquisition and response evaluation module, to continuously implement the periodic, adjustable scheme until the predetermined rehabilitation endpoint is reached or the clinical improvement standard compared with baseline is reached, thereby obtaining the brain-limb function remodeling and motor ability recovery effect of the subject.

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