Anti-dandruff and itching-relieving plant composition containing cacumen biotae extract and preparation method of anti-dandruff and itching-relieving plant composition

Abstract

The invention relates to the technical field of Chinese arborvitae twig and leaf extracts, and discloses a Chinese arborvitae twig and leaf extract-containing anti-dandruff and itching-relieving plant composition and a preparation method thereof, and the method comprises the following steps: preparation of a Chinese arborvitae twig and leaf ethanol extract, preparation of a water phase, preparation of an oil phase, emulsification, blending and post-treatment. A multi-target synergistic effect system is constructed by carefully selecting a Chinese arborvitae twig and leaf ethanol extract, curcumin, dipotassium glycyrrhizinate and oat beta-glucan and scientifically compounding; by utilizing the antibacterial and bacteriostatic properties of the cacumen biotae ethanol extract, the anti-inflammatory and anti-oxidation characteristics of curcumin, the soothing and repairing effects of dipotassium glycyrrhizinate and the barrier protection function of oat beta-glucan, malassezia reproduction can be inhibited, scalp inflammatory response can be relieved, and the damaged scalp barrier can be repaired, so that dandruff removal and lasting itching relieving are realized; meanwhile, all the components are natural, so that scalp irritation and drug resistance risks caused by chemical synthesis components are reduced, and the mildness and long-term use safety of the product are guaranteed.

Description

Technical Field

[0001] This invention relates to the field of Platycladus orientalis leaf extract technology, specifically to an anti-dandruff and antipruritic plant composition containing Platycladus orientalis leaf extract and its preparation method. Background Technology

[0002] Arborvitae leaf extract is widely used in the fields of medicine, health products and cosmetics. After the active ingredients of arborvitae leaf extract are absorbed by the scalp, they can activate hair matrix cells and promote blood circulation, restore the activity of hair follicles with declining hair growth ability, and replenish nutrients through blood circulation, thereby exerting good effects in preventing hair loss, darkening hair and nourishing hair.

[0003] Currently, commercially available anti-dandruff products generally rely on chemically synthesized ingredients. While inhibiting Malassezia and relieving scalp itching, they cannot simultaneously ensure gentleness and safety for long-term use. Frequent use of potent anti-dandruff ingredients can damage the scalp barrier and lead to drug resistance, making it impossible to guarantee the sustainability of scalp health.

[0004] Therefore, a plant-based composition containing arborvitae leaf extract for dandruff and itch relief, and its preparation method, are proposed to solve the above problems. Summary of the Invention

[0005] To address the shortcomings of existing technologies, this invention provides a dandruff-reducing and antipruritic plant composition containing Platycladus orientalis leaf extract and its preparation method, which solves the problems mentioned in the background art, such as scalp barrier damage and drug resistance, and the inability to guarantee the sustainability of scalp health.

[0006] To achieve the above objectives, the present invention provides the following technical solution: a plant-based composition for dandruff relief and itch relief containing Platycladus orientalis leaf extract and its preparation method, comprising the following raw materials in parts by weight: 20-40 parts of Platycladus orientalis leaf ethanol extract, 5-15 parts of curcumin, 3-8 parts of dipotassium glycyrrhizate, 2-6 parts of oat β-glucan, 100-200 parts of natural surfactant system, 0.5-2 parts of pH adjuster, 1-5 parts of thickener, and deionized water to 1000 parts; The ethanol extract of Platycladus orientalis leaves is prepared by the following method: dried Platycladus orientalis leaves are pulverized and passed through a 40-60 mesh sieve. A 60%-75% ethanol solution is added at a material-to-liquid ratio of 1:8-1:12. The extract is then extracted 2-3 times at 60-75℃ using an ultrasonic-microwave synergistic extraction device, each time for 20-40 minutes. The ultrasonic power is 300-500W, and the microwave power is 400-600W. The extracts are combined, filtered, and the filtrate is concentrated under vacuum until no alcohol odor is detected, yielding an extract. This extract is then purified using a macroporous adsorption resin. Impurities are first eluted with 3-5 column volumes of deionized water, followed by 4-6 column volumes of 80%-90% ethanol solution. The ethanol eluent is collected, concentrated, and dried to obtain the ethanol extract of Platycladus orientalis leaves. The natural surfactant system is composed of amino acid surfactants, alkyl glycosides and cocamidopropyl betaine in a mass ratio of (3-5):(2-4):(1-3).

[0007] Preferably, the macroporous adsorption resin is one of AB-8, HPD-600 or D101, and the ultrasonic frequency of the ultrasonic-microwave synergistic extraction device is 40 kHz.

[0008] Preferably, the amino acid surfactant is at least one of sodium lauroyl sarcosinate, sodium cocoyl glutamate, and sodium lauroyl methyl aminopropionate, the alkyl glycoside has an alkyl carbon chain length of C8-C14, and the active ingredient content of cocamidopropyl betaine is greater than 30%.

[0009] Preferably, it also contains 1-3 parts by weight of menthol and 0.5-2 parts by weight of paeonol, providing an immediate cooling sensation and enhanced antipruritic effect.

[0010] Preferably, it further comprises 0.5-2 parts by weight of a preservative, wherein the preservative is at least one of phenoxyethanol, octyl glycol or p-hydroxyacetophenone.

[0011] Preferably, the pH adjuster is one of citric acid, lactic acid, and sodium hydroxide, adjusting the final pH of the composition to 5.5-6.5, and the thickener is one of carbomer, xanthan gum, and hydroxyethyl cellulose.

[0012] Preferably, it includes the following steps: Step 1: Preparation of Platycladus orientalis leaf ethanol extract. Weigh dried Platycladus orientalis leaves according to the proportion, crush them, and then extract them by ultrasonic-microwave synergistic extraction, filtration, concentration, purification by macroporous adsorption resin, elution, further concentration and drying to obtain high-purity Platycladus orientalis leaf ethanol extract powder. Step 2: Aqueous phase preparation. Under stirring, dipotassium glycyrrhizate and oat β-glucan are added sequentially to deionized water and stirred until completely dissolved to form a homogeneous aqueous phase. Step 3: Oil phase preparation. Curcumin is mixed with a portion of cocamidopropyl betaine from the natural surfactant system and gently stirred until curcumin is completely dispersed to obtain a pre-dispersed oil phase. Preferably, the total amount of cocamidopropyl betaine in the natural surfactant system is 50%. Step 4: Emulsification and blending. Slowly add the pre-dispersed oil phase obtained in Step 3 to the aqueous phase obtained in Step 2, and homogenize and emulsify for 5-15 minutes. Then add the remaining natural surfactant system and the ethanol extract of Platycladus orientalis leaves, and continue stirring until completely dissolved and dispersed. Step 5: Post-processing. When the system temperature drops below 40℃, add pH adjuster and pre-dispersed thickener, then add menthol, paeonol and preservative. Stir and adjust to a suitable viscosity and pH value. Finally, add deionized water to make up to the total volume and stir evenly to obtain the dandruff-reducing and antipruritic plant composition.

[0013] Preferably, the emulsification temperature in step four is 70-75℃, the homogenizer speed is 1500-3000 r / min, and the thickener in step five needs to be pre-dispersed and swollen with some deionized water for at least 2 hours before being added.

[0014] Preferably, the eluent purified by the macroporous adsorption resin in step one is dried using spray drying technology, with the inlet temperature set at 160-180℃ and the outlet temperature controlled at 75-85℃, to obtain a fine extract powder with good flowability.

[0015] Preferably, in step four, after adding the ethanol extract of Platycladus orientalis leaves, panthenol, a natural moisturizer accounting for 0.5-1.5% of the total weight of the composition, is added, and the mixture is stirred continuously at 45-50°C for 15-20 minutes to fully integrate it before cooling and subsequent steps. Beneficial effects

[0016] Compared with the prior art, the present invention provides a plant-based composition for dandruff relief and itch relief containing arborvitae leaf extract and its preparation method, which has the following beneficial effects: 1. In this invention, a multi-target synergistic system is constructed by scientifically compounding carefully selected ethanol extract of Platycladus orientalis leaves, curcumin, dipotassium glycyrrhizate, and oat β-glucan. Utilizing the antibacterial and bacteriostatic properties of Platycladus orientalis leaf ethanol extract, the anti-inflammatory and antioxidant properties of curcumin, the soothing and repairing effects of dipotassium glycyrrhizate, and the barrier protection function of oat β-glucan, it can inhibit the reproduction of Malassezia, relieve scalp inflammation, and repair the damaged scalp barrier, thereby achieving dandruff removal and long-lasting itch relief. At the same time, all ingredients are derived from natural sources, reducing the risk of scalp irritation and drug resistance caused by chemically synthesized ingredients, ensuring the product's gentleness and safety for long-term use.

[0017] 2. In this invention, a specific process combining ultrasonic-microwave synergistic extraction with macroporous adsorption resin purification is used to prepare ethanol extract of Platycladus orientalis leaves. This process can efficiently and selectively enrich flavonoids and terpenoids, improving the purity and content of active ingredients and thus enhancing the core efficacy of the product. Furthermore, the preparation process involves pre-dispersing curcumin with a portion of cocamidopropyl betaine, followed by emulsification and homogenization at a specific temperature, and controlling the order of addition. This effectively solves the compatibility and chemical stability problems of various plant extracts in complex systems, avoiding efficacy loss due to aggregation, precipitation, and degradation of active ingredients, and ensuring the stability and efficacy consistency of the final product during its storage period.

[0018] 3. In this invention, a natural surfactant system composed of amino acid surfactants, alkyl glycosides, and cocamidopropyl betaine in a specific ratio is used. This system provides excellent cleaning and foaming capabilities while reducing the exfoliation and irritation to the scalp's stratum corneum. Its gentle properties complement the active ingredients of Platycladus orientalis leaf and curcumin, working together to maintain a healthy scalp microenvironment. Furthermore, menthol and paeonol can be added to the composition as needed to provide an immediate cooling sensation and enhance the anti-itch effect. The formulation can be flexibly adjusted to various forms such as shampoo and serum to meet different application scenarios and user preferences, demonstrating the flexibility and practicality of the formulation design. Detailed Implementation

[0019] The technical solutions of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present invention.

[0020] Example 1: A plant-based composition for dandruff and itch relief containing Platycladus orientalis leaf extract and its preparation method, comprising the following raw materials in parts by weight: 20 parts Platycladus orientalis leaf ethanol extract, 5 parts curcumin, 3 parts dipotassium glycyrrhizate, 2 parts oat β-glucan, 100 parts natural surfactant system, 0.5 parts pH adjuster, 1 part thickener, and deionized water to 1000 parts; The ethanol extract of Platycladus orientalis leaves was prepared by the following method: dried Platycladus orientalis leaves were pulverized and passed through a 40-mesh sieve. 60% ethanol solution was added at a material-liquid ratio of 1:8. The mixture was extracted twice at 60°C using an ultrasonic-microwave synergistic extraction device, 20 min each time, with an ultrasonic power of 300 W and a microwave power of 400 W. The extracts were combined, filtered, and the filtrate was concentrated under vacuum until there was no alcohol odor to obtain an extract. The extract was then purified using a macroporous adsorption resin. First, impurities were eluted with 3 column volumes of deionized water, and then eluted with 4 column volumes of 80% ethanol solution. The ethanol eluent was collected, concentrated, and dried to obtain the ethanol extract of Platycladus orientalis leaves. The natural surfactant system is composed of amino acid surfactants, alkyl glycosides and cocamidopropyl betaine in a mass ratio of 3:2:1. The macroporous adsorption resin is AB-8 type, and the ultrasonic frequency of the ultrasonic-microwave synergistic extraction device is 40kHz. The amino acid surfactant used is sodium lauroyl sarcosinate, the alkyl glycoside has an alkyl carbon chain length of C8-C14, and the active ingredient content of cocamidopropyl betaine is 30%. It also contains 1 part by weight of menthol and 0.5 parts by weight of paeonol, providing an instant cooling sensation and enhanced antipruritic effect; It also contains 0.5 parts by weight of a preservative, namely phenoxyethanol; The pH adjuster is citric acid, which adjusts the final pH of the composition to 5.5; the thickener is carbomer. Includes the following steps: Step 1: Preparation of Platycladus orientalis leaf ethanol extract. Weigh dried Platycladus orientalis leaves according to the proportion, crush them, and then extract them by ultrasonic-microwave synergistic extraction, filtration, concentration, purification by macroporous adsorption resin, elution, further concentration and drying to obtain high-purity Platycladus orientalis leaf ethanol extract powder. Step 2: Aqueous phase preparation. Under stirring, dipotassium glycyrrhizate and oat β-glucan are added sequentially to deionized water and stirred until completely dissolved to form a homogeneous aqueous phase. Step 3: Oil phase preparation. Curcumin is mixed with 50% cocamidopropyl betaine in the natural surfactant system and gently stirred until curcumin is completely dispersed to obtain a pre-dispersed oil phase. Step 4: Emulsification and blending. Slowly add the pre-dispersed oil phase obtained in Step 3 to the aqueous phase obtained in Step 2, homogenize and emulsify for 5 minutes, then add the remaining natural surfactant system and the ethanol extract of Platycladus orientalis leaves, and continue stirring until completely dissolved and dispersed. Step 5: Post-processing. When the system temperature drops below 40℃, add pH adjuster and pre-dispersed thickener, then add menthol, paeonol and preservative. Stir and adjust to a suitable viscosity and pH value. Finally, add deionized water to make up to the total volume and stir evenly to obtain the anti-dandruff and anti-itch plant composition. The emulsification temperature in step four is 70℃, and the homogenizer speed is 1500r / min. In step five, the thickener needs to be pre-dispersed and swollen with some deionized water for at least 2 hours before being added. The eluent purified by the macroporous adsorption resin in step one is dried using spray drying technology, with the inlet temperature set at 160℃ and the outlet temperature controlled at 75℃, to obtain a fine extract powder with good flowability. In step four, after adding the ethanol extract of Platycladus orientalis leaves, panthenol, a natural moisturizer, is added at 0.5% of the total weight of the composition. The mixture is then stirred continuously at 45°C for 15 minutes to allow it to fully integrate before cooling and proceeding with subsequent steps.

[0021] Example 2: A plant-based composition for dandruff and itch relief containing Platycladus orientalis leaf extract and its preparation method, comprising the following raw materials in parts by weight: 30 parts of Platycladus orientalis leaf ethanol extract, 10 parts of curcumin, 5 parts of dipotassium glycyrrhizate, 4 parts of oat β-glucan, 150 parts of natural surfactant system, 1.0 part of pH adjuster, 3 parts of thickener, and deionized water to 1000 parts; The ethanol extract of Platycladus orientalis leaves was prepared by the following method: dried Platycladus orientalis leaves were pulverized and passed through a 50-mesh sieve. 65% ethanol solution was added at a material-liquid ratio of 1:10. The extract was extracted twice at 65°C using an ultrasonic-microwave synergistic extraction device for 30 minutes each time, with an ultrasonic power of 400W and a microwave power of 500W. The extracts were combined, filtered, and the filtrate was concentrated under vacuum until there was no alcohol odor to obtain an extract. The extract was then purified using a macroporous adsorption resin. First, impurities were eluted with 4 column volumes of deionized water, and then eluted with 5 column volumes of 85% ethanol solution. The ethanol eluent was collected, concentrated, and dried to obtain the ethanol extract of Platycladus orientalis leaves. The natural surfactant system is composed of amino acid surfactants, alkyl glycosides and cocamidopropyl betaine in a mass ratio of 4:3:2. The macroporous adsorption resin is AB-8 type, and the ultrasonic frequency of the ultrasonic-microwave synergistic extraction device is 40kHz. The amino acid surfactant used is sodium lauroyl sarcosinate, the alkyl glycoside has an alkyl carbon chain length of C8-C14, and the active ingredient content of cocamidopropyl betaine is 30%. It also contains 2 parts by weight of menthol and 1.0 part by weight of paeonol, providing an instant cooling sensation and enhanced antipruritic effect; It also contains 1.0 part by weight of a preservative, which is phenoxyethanol; The pH adjuster is citric acid, which adjusts the final pH of the composition to 6.0; the thickener is carbomer. Includes the following steps: Step 1: Preparation of Platycladus orientalis leaf ethanol extract. Weigh dried Platycladus orientalis leaves according to the proportion, crush them, and then extract them by ultrasonic-microwave synergistic extraction, filtration, concentration, purification by macroporous adsorption resin, elution, further concentration and drying to obtain high-purity Platycladus orientalis leaf ethanol extract powder. Step 2: Aqueous phase preparation. Under stirring, dipotassium glycyrrhizate and oat β-glucan are added sequentially to deionized water and stirred until completely dissolved to form a homogeneous aqueous phase. Step 3: Oil phase preparation. Curcumin is mixed with 50% cocamidopropyl betaine in the natural surfactant system and gently stirred until curcumin is completely dispersed to obtain a pre-dispersed oil phase. Step 4: Emulsification and blending. Slowly add the pre-dispersed oil phase obtained in Step 3 to the aqueous phase obtained in Step 2, homogenize and emulsify for 10 minutes, then add the remaining natural surfactant system and the ethanol extract of Platycladus orientalis leaves, and continue stirring until completely dissolved and dispersed. Step 5: Post-processing. When the system temperature drops below 40℃, add pH adjuster and pre-dispersed thickener, then add menthol, paeonol and preservative. Stir and adjust to a suitable viscosity and pH value. Finally, add deionized water to make up to the total volume and stir evenly to obtain the anti-dandruff and anti-itch plant composition. The emulsification temperature in step four is 72℃, the homogenizer speed is 2000r / min, and the thickener in step five needs to be pre-dispersed and swollen with some deionized water for at least 2 hours before being added. The eluent purified by the macroporous adsorption resin in step one is dried using spray drying technology, with the inlet temperature set at 170℃ and the outlet temperature controlled at 80℃, to obtain a fine extract powder with good flowability. In step four, after adding the ethanol extract of Platycladus orientalis leaves, panthenol, a natural moisturizer accounting for 1.0% of the total weight of the composition, is added, and the mixture is stirred continuously at 47°C for 18 minutes to fully integrate it before cooling and subsequent steps.

[0022] Example 3: A plant-based composition for dandruff and itch relief containing Platycladus orientalis leaf extract and its preparation method, which is made from the following raw materials in parts by weight: 40 parts of Platycladus orientalis leaf ethanol extract, 15 parts of curcumin, 8 parts of dipotassium glycyrrhizate, 6 parts of oat β-glucan, 200 parts of natural surfactant system, 2 parts of pH adjuster, 5 parts of thickener, and deionized water added to 1000 parts. The ethanol extract of Platycladus orientalis leaves was prepared by the following method: dried Platycladus orientalis leaves were pulverized and passed through a 60-mesh sieve. 75% ethanol solution was added at a material-to-liquid ratio of 1:12. The extract was extracted three times at 75°C using an ultrasonic-microwave synergistic extraction device for 40 minutes each time. The ultrasonic power was 500W and the microwave power was 600W. The extracts were combined, filtered, and the filtrate was concentrated under vacuum until there was no alcohol odor to obtain an extract. The extract was then purified using a macroporous adsorption resin. First, impurities were eluted with 5 column volumes of deionized water, and then eluted with 6 column volumes of 90% ethanol solution. The ethanol eluent was collected, concentrated, and dried to obtain the ethanol extract of Platycladus orientalis leaves. The natural surfactant system is composed of amino acid surfactants, alkyl glycosides and cocamidopropyl betaine in a mass ratio of 5:4:3. The macroporous adsorption resin is AB-8 type, and the ultrasonic frequency of the ultrasonic-microwave synergistic extraction device is 40kHz. The amino acid surfactant used is sodium lauroyl sarcosinate, the alkyl glycoside has an alkyl carbon chain length of C8-C14, and the active ingredient content of cocamidopropyl betaine is 30%. It also contains 3 parts by weight of menthol and 2 parts by weight of paeonol, providing an instant cooling sensation and enhanced antipruritic effect; It also contains 2 parts by weight of preservative, which is phenoxyethanol; The pH adjuster is citric acid, which adjusts the final pH of the composition to 6.5; the thickener is carbomer. Includes the following steps: Step 1: Preparation of Platycladus orientalis leaf ethanol extract. Weigh dried Platycladus orientalis leaves according to the proportion, crush them, and then extract them by ultrasonic-microwave synergistic extraction, filtration, concentration, purification by macroporous adsorption resin, elution, further concentration and drying to obtain high-purity Platycladus orientalis leaf ethanol extract powder. Step 2: Aqueous phase preparation. Under stirring, dipotassium glycyrrhizate and oat β-glucan are added sequentially to deionized water and stirred until completely dissolved to form a homogeneous aqueous phase. Step 3: Oil phase preparation. Curcumin is mixed with 50% cocamidopropyl betaine in the natural surfactant system and gently stirred until curcumin is completely dispersed to obtain a pre-dispersed oil phase. Step 4: Emulsification and blending. Slowly add the pre-dispersed oil phase obtained in Step 3 to the aqueous phase obtained in Step 2, and homogenize and emulsify for 15 minutes. Then add the remaining natural surfactant system and the ethanol extract of Platycladus orientalis leaves, and continue stirring until completely dissolved and dispersed. Step 5: Post-processing. When the system temperature drops below 40℃, add pH adjuster and pre-dispersed thickener, then add menthol, paeonol and preservative. Stir and adjust to a suitable viscosity and pH value. Finally, add deionized water to make up to the total volume and stir evenly to obtain the anti-dandruff and anti-itch plant composition. The emulsification temperature in step four is 75℃, and the homogenizer speed is 3000r / min. In step five, the thickener needs to be dispersed and swollen with some deionized water for at least 2 hours before being added. The eluent purified by the macroporous adsorption resin in step one is dried using spray drying technology, with the inlet temperature set at 180℃ and the outlet temperature controlled at 85℃, to obtain a fine extract powder with good flowability. In step four, after adding the ethanol extract of Platycladus orientalis leaves, panthenol, a natural moisturizer accounting for 1.5% of the total weight of the composition, is added, and the mixture is stirred continuously at 50°C for 20 minutes to fully integrate it before cooling and subsequent steps.

[0023] Comparative Example 1: The difference between this comparative example and Example 1 is that no ethanol extract of Platycladus orientalis leaves was added when preparing the composition in this comparative example.

[0024] Comparative Example 2: The difference between this comparative example and Example 2 is that curcumin was not added when preparing the composition in this comparative example.

[0025] Comparative Example 3 differs from Example 3 in that the extract of Platycladus orientalis leaf was not purified using macroporous adsorption resin.

[0026] Comparative Example 4 differs from Example 3 in that: this comparative example did not use a natural surfactant system composed of amino acid surfactants, alkyl glycosides and cocamidopropyl betaine in the preparation process, but instead used a conventional sodium lauryl ether sulfate (SLES) system.

[0027] The anti-dandruff and antipruritic plant compositions prepared in Examples 1-3 and Comparative Examples 1-4 were subjected to performance tests. The test items and test methods are as follows: Anti-dandruff efficacy test: The Malassezia inhibition zone test was used. The prepared composition sample was prepared into a solution of a certain concentration, inoculated with a standard strain of Malassezia, and then cultured and observed for the size of the inhibition zone. Anti-itch efficacy test: Human trial was conducted, recruiting volunteers with scalp itching symptoms, and recording the degree of itching reduction after using the sample; Stability test: The sample was placed in a 40℃ constant temperature chamber for 30 days, and its physicochemical stability and changes in the content of active ingredients were observed. Mildness test: Patch test is used to assess the irritation of the sample to human skin.

[0028] The test data of the anti-dandruff and antipruritic plant compositions prepared in Examples 1-3 and Comparative Examples 1-4 are recorded in the table below:

[0029] Comparison and analysis of the data in the table show that the anti-dandruff and anti-itch herbal compositions containing Platycladus orientalis leaf extract prepared using the processes in Examples 1-3 exhibit significantly superior performance compared to the compositions prepared using the processes in Comparative Examples 1-4. This indicates that by scientifically combining Platycladus orientalis leaf ethanol extract, curcumin, dipotassium glycyrrhizate, and oat β-glucan, a multi-target synergistic system is constructed. Utilizing the antibacterial and bacteriostatic properties of Platycladus orientalis leaf ethanol extract, the anti-inflammatory and antioxidant properties of curcumin, the soothing and repairing effects of dipotassium glycyrrhizate, and the barrier protection function of oat β-glucan, it is possible to inhibit the proliferation of Malassezia, alleviate scalp inflammation, and repair the damaged scalp barrier, thereby achieving dandruff removal and long-lasting anti-itch effects. Simultaneously, the entire formula is derived from natural ingredients, reducing the risks of scalp irritation and drug resistance associated with chemically synthesized components, ensuring the product's gentleness and long-term safety. The specific process of preparing Platycladus orientalis leaf ethanol extract using ultrasonic-microwave synergistic extraction combined with macroporous adsorption resin purification can efficiently and selectively enrich flavonoids and terpenoid active ingredients, improving the purity and content of the effective components. This enhances the product's core efficacy. Furthermore, the preparation process involves pre-dispersing curcumin and a portion of cocamidopropyl betaine, followed by emulsification and homogenization at a specific temperature, with controlled addition order. This effectively solves the compatibility and chemical stability challenges of various plant extracts in complex systems, preventing efficacy loss due to aggregation, precipitation, and degradation of active ingredients. It ensures the stability and efficacy consistency of the final product during its shelf life. The use of a natural surfactant system composed of amino acid surfactants, alkyl glycosides, and cocamidopropyl betaine in specific proportions provides excellent cleaning and foaming capabilities while reducing exfoliation and irritation to the scalp's stratum corneum. Its gentle properties complement the active ingredients of arborvitae leaf and curcumin, working together to maintain a healthy scalp microenvironment. In addition, menthol and paeonol can be added as needed to provide an immediate cooling sensation and enhance anti-itch effects. The formulation can be flexibly adjusted to include shampoo and serum to meet different application scenarios and user preferences, demonstrating the flexibility and practicality of the formulation design.

[0030] By comparing and analyzing the relevant data in the table, it can be seen that the anti-dandruff and anti-itch plant composition obtained by the preparation process of the present invention not only has the effects of anti-dandruff and anti-itch, but also has good stability and mildness. This indicates that the anti-dandruff and anti-itch plant composition containing arborvitae leaf extract and its preparation method provided by the present invention have a broader market prospect and are more suitable for promotion.

[0031] It should be noted that, in this document, relational terms such as "first" and "second" are used only to distinguish one entity or operation from another, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Furthermore, the terms "comprising," "including," or any other variations thereof are intended to cover non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements includes not only those elements but also other elements not expressly listed, or elements inherent to such a process, method, article, or apparatus. Without further limitations, an element defined by the phrase "comprising one..." does not exclude the presence of other identical elements in the process, method, article, or apparatus that includes said element.

[0032] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A herbal composition for dandruff and itch relief containing arborvitae leaf extract, characterized in that, It is made from the following raw materials in parts by weight: 20-40 parts of ethanol extract of Platycladus orientalis leaves, 5-15 parts of curcumin, 3-8 parts of dipotassium glycyrrhizate, 2-6 parts of oat β-glucan, 100-200 parts of natural surfactant system, 0.5-2 parts of pH adjuster, 1-5 parts of thickener, and deionized water to 1000 parts. The ethanol extract of Platycladus orientalis leaves is prepared by the following method: dried Platycladus orientalis leaves are pulverized and passed through a 40-60 mesh sieve. A 60%-75% ethanol solution is added at a material-to-liquid ratio of 1:8-1:

12. The extract is then extracted 2-3 times at 60-75℃ using an ultrasonic-microwave synergistic extraction device, each time for 20-40 minutes. The ultrasonic power is 300-500W, and the microwave power is 400-600W. The extracts are combined, filtered, and the filtrate is concentrated under vacuum until no alcohol odor is detected, yielding an extract. This extract is then purified using a macroporous adsorption resin. Impurities are first eluted with 3-5 column volumes of deionized water, followed by 4-6 column volumes of 80%-90% ethanol solution. The ethanol eluent is collected, concentrated, and dried to obtain the ethanol extract of Platycladus orientalis leaves. The natural surfactant system is composed of amino acid surfactants, alkyl glycosides and cocamidopropyl betaine in a mass ratio of (3-5):(2-4):(1-3).

2. The anti-dandruff and antipruritic herbal composition containing Platycladus orientalis leaf extract according to claim 1, characterized in that, The macroporous adsorption resin is one of AB-8, HPD-600 or D101, and the ultrasonic frequency of the ultrasonic-microwave synergistic extraction device is 40kHz.

3. The anti-dandruff and antipruritic herbal composition containing Platycladus orientalis leaf extract according to claim 1, characterized in that: The amino acid surfactant is at least one of sodium lauroyl sarcosinate, sodium cocoyl glutamate, and sodium lauroyl methyl aminopropionate, the alkyl glycoside has an alkyl carbon chain length of C8-C14, and the active ingredient content of cocamidopropyl betaine is greater than 30%.

4. The anti-dandruff and antipruritic herbal composition containing Platycladus orientalis leaf extract according to claim 1, characterized in that, It also contains 1-3 parts by weight of menthol and 0.5-2 parts by weight of paeonol, providing an immediate cooling sensation and enhanced antipruritic effect.

5. The anti-dandruff and antipruritic herbal composition containing Platycladus orientalis leaf extract according to claim 1, characterized in that, It also contains 0.5-2 parts by weight of a preservative, said preservative being at least one of phenoxyethanol, octyl glycol and p-hydroxyacetophenone.

6. The anti-dandruff and antipruritic herbal composition containing Platycladus orientalis leaf extract according to claim 1, characterized in that, The pH adjuster is one of citric acid, lactic acid, and sodium hydroxide, which adjusts the final pH of the composition to 5.5-6.

5. The thickener is one of carbomer, xanthan gum, and hydroxyethyl cellulose.

7. A method for preparing an anti-dandruff and antipruritic herbal composition containing Platycladus orientalis leaf extract, achieving the anti-dandruff and antipruritic herbal composition containing Platycladus orientalis leaf extract according to any one of claims 1-6, characterized in that: Includes the following steps: Step 1: Preparation of Platycladus orientalis leaf ethanol extract. Weigh dried Platycladus orientalis leaves according to the proportion, crush them, and then extract them by ultrasonic-microwave synergistic extraction, filtration, concentration, purification by macroporous adsorption resin, elution, further concentration and drying to obtain high-purity Platycladus orientalis leaf ethanol extract powder. Step 2: Aqueous phase preparation. Under stirring, dipotassium glycyrrhizate and oat β-glucan are added sequentially to deionized water and stirred until completely dissolved to form a homogeneous aqueous phase. Step 3: Oil phase preparation. Curcumin is mixed with a portion of cocamidopropyl betaine from the natural surfactant system and gently stirred until curcumin is completely dispersed to obtain a pre-dispersed oil phase. Step 4: Emulsification and blending. Slowly add the pre-dispersed oil phase obtained in Step 3 to the aqueous phase obtained in Step 2, and homogenize and emulsify for 5-15 minutes. Then add the remaining natural surfactant system and the ethanol extract of Platycladus orientalis leaves, and continue stirring until completely dissolved and dispersed. Step 5: Post-processing. When the system temperature drops below 40℃, add the pH adjuster and the pre-dispersed thickener, stir to adjust to a suitable viscosity and pH value, and finally add deionized water to make up to the full volume. Stir evenly to obtain the dandruff-reducing and antipruritic plant composition.

8. A method for preparing a dandruff-reducing and antipruritic plant composition containing Platycladus orientalis leaf extract according to claim 7, characterized in that: The emulsification temperature in step four is 70-75℃, and the homogenizer speed is 1500-3000r / min. In step five, the thickener needs to be pre-dispersed and swollen with some deionized water for at least 2 hours before being added.

9. A method for preparing a dandruff-reducing and antipruritic plant composition containing Platycladus orientalis leaf extract according to claim 7, characterized in that, The eluent purified by the macroporous adsorption resin in step one is dried using spray drying technology, with the inlet temperature set at 160-180℃ and the outlet temperature controlled at 75-85℃, to obtain a fine extract powder with good flowability.

10. A method for preparing a dandruff-reducing and antipruritic plant composition containing Platycladus orientalis leaf extract according to claim 7, characterized in that, In step four, after adding the ethanol extract of Platycladus orientalis leaves, panthenol, a natural moisturizer accounting for 0.5-1.5% of the total weight of the composition, is added, and the mixture is stirred continuously at 45-50°C for 15-20 minutes to fully integrate it before cooling and subsequent steps.

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