A pharmaceutical composition comprises a
drug component. The
drug component is a combination of one pharmaceutically acceptable salt of
glycopyrrolate, beclomethasone dipropionate, and one
long acting beta-2-
agonist (LABA) selected from
formoterol and pharmaceutically acceptable salts thereof. The pharmaceutical composition also comprises a
propellant component. The
propellant component is at least 90 weight percent 1,1-difluoroethane (HFA-152a). The pharmaceutical composition is in the form of a solution and optionally comprises
ethanol, but is free of other polar solvents / co-solvents. The
drug component is the sole drug component in the pharmaceutical composition.