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Novel adenine compound and use thereof
InactiveUS20060052403A1Suppressing systemic adverse effectFast metabolismBiocideOrganic chemistryOxygen atomCompound (substance)
A drug for topically administration which is effective as an antiallergic agent. The drug for topically administration contains as an active ingredient an adenine compound represented by the general formula (1): [wherein ring A represents a 6 to 10 membered, mono or bicyclic, aromatic hydrocarbon or a 5 to 10 membered, mono or bicyclic, aromatic heterocycle containing one to three heteroatoms selected among 0 to 2 nitrogen atoms, 0 or 1 oxygen atom, and 0 or 1 sulfur atom; n is an integer of 0 to 2; m is an integer of 0 to 2; R represents halogeno, (un)substituted alkyl, etc.; X1 represents oxygen, sulfur, NR1 (R1 represents hydrogen or alkyl), or a single bond; Y1 represents a single bond, alkylene, etc.; Y2 represents a single bond, alkylene, etc.; Z represents alkylene; and at least one of Q1 and Q2 represents —COOR10 (wherein R10 represents (un)substituted alkyl, etc.), etc.] or a pharmaceutically acceptable salt of the compound.
Owner:SUMITOMO DAINIPPON PHARMA CO LTD
Biocompatible hemostatic, antiblocking, healing-promoting and surgical wound-closing modified starch material
InactiveCN101485897AMaterials that promote healingPromote repairOrganic active ingredientsSurgical adhesivesTissue fluidBandage
The invention relates to a modified starch material for biocompatible hemostasis, biocompatible anti-adhesion, tissue healing promotion, absorbable surgery sealing and tissue adhesion. The invention applies biocompatible modified starch to animal tissues, wherein the modified starch material has the molecular weight of more than 15,000 daltons, and the particle diameter of between 1 and 1,000 mu m. The modified starch hemostatic material has stypticity, reduces hemorrhage, blood oozing and tissue fluid oozing of wounds, maintains relative moistening or drying of wound surfaces or the wounds, inhibits bacterium growth and inflammation reaction, and contributes to locally diminish inflammation of the wounds and relieve pain of patients. Moreover, the modified starch material can wash local parts after operation is over and remove redundant modified starch which does not participate in hemostasis, and can easily remove haemostatic under the condition of debridement treatment after self-help and first-aid treatment of war wounds; and hemostatic materials with a small amount of modified starch can be absorbed by the body, so that the pain of tearing of gauzes and bandages on people is avoided.
Owner:BEIJING UNIVERSAL LIKANG TECH CO LTD
Treatment of cellulite and adipose tissue with mid-infrared radiation
InactiveUS20080188835A1Avoid epidermal damagePoor absorptionSurgical needlesSurgical instrument detailsLaser assisted liposuctionMid infrared
A handpiece and method of use for laser-assisted liposuction for melting, disrupting, and removing cellulite and adipose tissue. Electromagnetic energy is used to selectively melt or disrupt cellulite and adipose tissue and ablate the collagen in the constricting bands of connective tissue that causes the dimpled appearance of cellulite and adipose tissue, while avoiding damage to the surrounding fatty cells.
Owner:NEW STAR LASERS
Modified starch absorbable hemostasia material and preparation method thereof
ActiveCN101361986AHigh viscosityImprove water absorption speedSurgical adhesivesPharmaceutical delivery mechanismWound healingBiomedical engineering
Owner:BEIJING UNIVERSAL LIKANG TECH CO LTD
Adenine compound and use thereof
InactiveUS7754728B2Suppressing systemic adverse effectFast metabolismBiocideOrganic chemistryChemical compoundPharmaceutical drug
A drug for topically administration which is effective as an antiallergic agent. The drug for topically administration contains as an active ingredient an adenine compound represented by the general formula (1):[wherein ring A represents a 6 to 10 membered, mono or bicyclic, aromatic hydrocarbon or a 5 to 10 membered, mono or bicyclic, aromatic heterocycle containing one to three heteroatoms selected among 0 to 2 nitrogen atoms, 0 or 1 oxygen atom, and 0 or 1 sulfur atom; n is an integer of 0 to 2; m is an integer of 0 to 2; R represents halogeno, (un)substituted alkyl, etc.; X1 represents oxygen, sulfur, NR1 (R1 represents hydrogen or alkyl), or a single bond; Y1 represents a single bond, alkylene, etc.; Y2 represents a single bond, alkylene, etc.; Z represents alkylene; and at least one of Q1 and Q2 represents —COOR10 (wherein R10 represents (un)substituted alkyl, etc.), etc.] or a pharmaceutically acceptable salt of the compound.
Owner:SUMITOMO DAINIPPON PHARMA CO LTD
Methionine containing animal cell culture medium and its use
InactiveUS6309862B1Facilitates purification of desired productEasy to prepareCulture processCell culture mediaBiotechnologyWhite blood cell
A nutrient medium for protein producing cells, characterized in that said medium consists essentially of the following components: a physiological saline containing Ca2+, K+, Mg2+ and Na+, an energy source, a pH buffer and methionine in an amount of 0.015-2.0 g / liter, and optionally antibiotics. The invention further relates to use of the nutrient medium for cells and human leukocytes.
Owner:SWEDISH ORPHAN INT
Biocompatibility pre-gelatinized modified starch and preparation thereof
InactiveCN101497670AAbsorbentSpeed up absorptionSurgical adhesivesFibre treatmentBiocompatibility TestingHigh pressure
The invention relates to a biocompatible pre-gelatinized modified starch. The water absorbency is not less than one time, and the biocompatible pre-gelatinized modified starch is taken as biocompatible hemostatic material, biocompatible anti-blocking material, biocompatible tissue-healing promoting material, biocompatible surgical sealant or biocompatible wound closure tissue glue. The invention has the advantages that the biocompatible pre-gelatinized modified starch is directly acted on the wounded area with blood for immediately stopping bleeding, has obviously increased water absorbency and speed of water absorption and greater viscosity and stickiness and further plays the role in preventing the tissue and the blood vessel from being damaged during the process of stopping bleeding; the modified starch is easy to swell or dissolve in water, and is washed by normal saline after the bleeding stopping so as to reduce the residual in the body, to be favorable for wound healing and to avoid the pain due to tearing the gauze and the bandage out; the pre-gelatinized modified starch has the actions of bacterial resistance and anti-inflammatory; and the pre-gelatinized modified starch is stable, not easy to decompose, long in guarantee period, convenient for storage, resistant at high pressure and low pressure, resistant at high temperature and low temperature and not easy to change the physicochemical characteristics.
Owner:纪欣
Structured Lipid Compositions And Methods Of Formulation Thereof
ActiveUS20090123634A1High energyIncrease valueFood preparationEdible oils/fats with aqeous phaseTriglycerideWeight management
Lipid compositions comprising specific mixtures of edible synthetic triglycerides are provided that are useful in formulating food products having highly desirable dietary benefits. The novel lipid compositions allow simultaneous access to highly desirable dietary benefits such as delivery of calorie reduction, weight management, health benefits, or any combination thereof, and they also may be formulated trans-fatty acid free.
Owner:INTERCONTINENTAL GREAT BRANDS LLC
Bioaugmentation treatment technology of high ammonia nitrogen wastewater
InactiveCN101973678AIncrease the number ofSmall footprintMultistage water/sewage treatmentHigh concentrationSludge
The invention relates to a bioaugmentation treatment technology of the high ammonia nitrogen wastewater. The treatment technology is characterized in that under the condition that dissolved oxygen exists in the high ammonia nitrogen wastewater, an aerobic pool, an aerobic filter and a membrane pool are established, wherein by utilizing the metabolism of the aerobic microorganism, high concentration of organic substances are degraded, the organic substances with high molecular weight and energy are converted to substances with low molecular weight and energy; the aerobic pool adopts internal circulation and large-scale external circulation hydraulic agitation; and the aerobic filter is filled with novel fixed enzyme-floating filler and immobilized microorganism and microporous aeration and jet aeration are combined for aeration, thus the flow pattern of the nitrification filter is improved. Compared with the prior art, the system of the invention has high sludge concentration and the corresponding volume loading is also high, thus the floor space is small and the capital cost is low; the conversion rate and utilization rate of atmospheric oxygen is high, the effect of mass transfer is good, the anti-shock loading capability of the system is high, the effluent quality is stable; the operating cost is low; the density is increased relatively, the solid-liquid separating effect is good and the yield of excess sludge is low.
Owner:SHANGHAI HONESS ENVIRONMENTAL TECH CORP
Polysaccharide macromolecular paramagnetic metal complex and synthesis method and application thereof
InactiveCN101619106AIncreased toxicityShort retention timeIn-vivo testing preparationsLymphatic vesselSynthesis methods
The invention relates to a polysaccharide macromolecular paramagnetic metal complex and a synthesis method and an application thereof. Polysaccharide macromolecules are used as carriers, and a ligand compound, the side chains of which contain open-chain or annular polyamino polycarboxylic compounds, acts with paramagnetic metal ions to form the paramagnetic metal complex, wherein the paramagnetic metal ions are positive divalent or trivalent ions of metal elements, the atomic numbers of which are 21-29, 42 and 44 or 57-71. The polysaccharide macromolecular paramagnetic metal complex can be used as a magnetic resonance imaging contrast agent for lymphatic organs, lymphatic vessels, lymphatic systems and cardiovascular systems of people or other mammals.
Owner:WUHAN INSTITUTE OF TECHNOLOGY
Ester combination local anesthetic
InactiveUS20050137177A1Low risk of toxicityRapid actionBiocideAnimal repellantsPain durationChemical toxicity
The present invention provides compositions and methods for improved local anesthesia and / or analgesia, in which onset of action is rapid, the risk of toxicity is low, and the effect is sustained. More particularly, the present invention provides a combination of at least two ester anesthetics for administration to a subject, where at least one ester anesthetic provides a rapid onset of action and at least one ester anesthetic provides sustained activity. The compositions of the present invention are useful for the production of analgesia and / or anesthesia and are particularly useful for the prophylaxis and / or treatment of pain.
Owner:THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV
Application of near infrared-emission fluorescent probe in quick pesticide residue detection
ActiveCN108318467AFast metabolismRapid responseFluorescence/phosphorescencePesticide residueEnzyme inhibition
The invention discloses application of a near infrared-emission fluorescent probe in quick pesticide residue detection and belongs to the technical field of quick pesticide detection. The probe is based on rhoda-fluor fluorescence matrix and has specific activity on acetylcholine esterase AChE; by means of an enzyme inhibition detection principle, the probe can be applied to quick detection of organophosphorus pesticide and carbamate pesticide residues in food. The acetylcholine esterase AChE is extracted from duck blood; in an appropriate probe substrate range, enzyme activity and an inhibition rate can be represented by quantitatively detecting fluorescence intensity change of the probe. Four pesticide detection standard curves have small error, and R<2> is larger than 0.98; vegetable pesticide adding standard recovery most reaches 80 to 110%, so that the near infrared-emission fluorescent probe disclosed by the invention can be applied to quantitative, ppb-grade and quick detectionof organophosphorus and carbamate pesticide residues in the food.
Owner:王铮
Anesthesia arousal composition
InactiveUS20090131338A1Facilitates early postoperative awakeningIncrease protein bindingBiocideNervous disorderSodium bicarbonateGlucose polymers
A method for facilitating postoperative awakening of patients from anesthesia does not depend on the experience of anesthesiologists. Also provided are an anesthesia arousal composition for use in this method and a preparation containing a bicarbonate ion that facilitates awakening from anesthesia. Specifically, the anesthesia arousal composition is provided in the form of infusion fluid. The method for controlling and facilitating awakening from anesthesia involves administering the anesthesia arousal composition. The present invention preferably provides an anesthesia arousal composition or an acidosis-correcting composition containing sodium bicarbonate as a major component that serves as a source of the bicarbonate ion, along with each or a combination of another electrolyte, glucose and an amino acid.
Owner:EA PHARMA CO LTD
Cholinesterase inhibitors to treat disorders of attention
InactiveUS7105540B2Augmenting cholinergic transmissionLong duration of actionBiocideNervous disorderCholinesteraseCholinesterase inhibition
The present invention provides novel methods of treating disorders of attention or improving attention in humans by administering an effective amount of a cholinesterase inhibitor.
Owner:EISIA R&D MANAGEMENT CO LTD
Bacillussubtilis and application thereof in raising Apostichopus japonicus
InactiveCN102134558AGrowth inhibitionInhibition of reproductionBiocideBacteriaEcological environmentMetabolite
The invention relates to separation of Bacillussubtilis and application of the Bacillussubtilis in raising Apostichopus japonicus. The Bacillussubtilis can effectively inhibit vibriones and other pathogenic bacteria from breeding, and promote the growth of the Apostichopus japonicus. The strain is separated from gills of fished captured in the Dalian sea area, and is preserved by China General Microbiological Culture Collection Center with the collection number of CGMCC No.3498. The Bacillussubtilis can be widely applied to breeding and production links in the fishery industry, can degrade, convert and metabolize metabolic products in the breeding and production processes, creates good ecological environment, and improves, preserves and repairs the ecological environment of water resources to fulfill the aims of reducing self-pollution, reducing medicinal harm, reducing cost, lightening the pollution of the aquaculture to the whole ecological environment and improving the quality of cultured products.
Owner:LIAONING OCEAN & FISHERIES SCI RES INST
Shewanella-decolorationis-based microbial fuel cell and using method thereof
InactiveCN102315471ASimplify how to runImprove environmental adaptabilityFinal product manufactureBiochemical fuel cellsElectron donorOxygen
The invention discloses a Shewanella-decolorationis-based microbial fuel cell and a using method thereof. The microbial fuel cell comprises an anode chamber, a cathode chamber, an anode electrode, a cathode electrode, a proton permeation film and an external circuit, wherein a microorganism is inoculated in the anode chamber; the anode chamber is also filled with a culture solution and electron donors of the microorganism; the cathode chamber is filled with cathode reaction liquid; and the microorganism is Shewanella decolorationis. The microbial fuel cell takes the Shewanella decolorationis as an anode microorganism; and the Shewanella decolorationis has extremely high environmental suitability and a variety of breathing mechanisms. In the nutrient-rich anode culture solution, the Shewanella decolorationis can metabolize and reproduce quickly, and consume dissolved oxygen to maintain an anaerobic environment around the anode electrode in an extremely short time; therefore, the step of blowing nitrogen to manufacture the anaerobic environment and keep an anaerobic reaction condition of a common microbial fuel cell before starting or in operation can be eliminated; an operation operating method is simplified; and the Shewanella-decolorationis-based microbial fuel cell has a good application prospect in the treatment and the recycling of environmental pollutants.
Owner:GUANGDONG INST OF MICROORGANISM
Soybean peptide energy recovery gel and preparation method thereof
InactiveCN103704560AGood bean flavorImprove liquidityFood ingredient functionsFood preparationFruit juiceEnergy recovery
The invention discloses soybean peptide energy recovery gel and a preparation method thereof. The soybean peptide energy recovery gel is prepared from the following raw materials in parts by weight: 50-60 parts of corn starch, 10-15 parts of honey, 15-20 parts of concentrated fruit juice, 10-15 parts of concentrated lemon juice, 15-20 parts of soybean peptide powder and 5-10 parts of xylitol. The preparation method comprises the steps of 1, pretreating an aqueous solution containing 10% of soybean protein powder at 90 DEG C for 20min; 2, making corn starch gel; 3, adding the corn starch gel made in the second step into the soybean protein powder made in the first step as well as the concentrated fruit juice, the honey and the xylitol to obtain the finished soybean peptide energy recovery gel product. The soybean peptide energy recovery gel has the beneficial effects that the fatigue resistance is extremely high, and the gel with a certain amount of soybean peptide powder can well meet a demand of people feeling tired; the stability of the gel is higher than that of the starch, and the requirement on stability of energy gel can be met.
Owner:JILIN UNIV
Meal replacement jelly powder and preparation method thereof
ActiveCN102871011AImprove freshnessGreat tasteFood preparationMeal replacementGamma-Aminobutyric acid
The invention relates to meal replacement jelly powder and a preparation method thereof. The meal replacement jelly powder comprises the following components in parts by weight: 20-35% of polydextrose, 1-8% of isomaltulose, 5-15% of konjac glucomannan, 4-10% of carageenan, 0.1-1% of gamma aminobutyric acid and 0.3-1.4% of collagen. According to the meal replacement jelly powder and the preparation method, a jelly form is adopted, so that the product has a good taste and an attractive appearance. Satiety is improved by adding a substance with a meal replacement effect into the meal replacement jelly powder, so that the purpose of slimming is achieved.
Owner:BEIJING COMPETITOR SPORTS SCI & TECH
Fermentation method for improving yield of isoleucine
The invention discloses a fermentation method for improving the yield of isoleucine. The fermentation method comprises the following steps: culturing microorganisms, fermenting, separating fermentation liquor, carrying out ion exchange on fermentation supernatant, deaminizing with a deamination tower, decolorizing with activated carbon and crystallizing by evaporating. Because the corn steep liquor which serves as a hydrolysis liquor in the culture medium and accounts for 40% of the total weight of the culture medium replaces the hydrochloric acid adopted by the traditional method to regulate the pH value, the corrosion of the hydrochloric acid to the stainless steel tank is avoided. In addition, because biotin and VB1 are used as growth factors in the process, the viscosity of the fermentation liquor can be reduced, the respiratory metabolism of the microorganisms can be promoted, and the down-stream finished product can be extracted easily. By adopting the fermentation method disclosed by the invention, a good fermentation index can be achieved, the yield of the isoleucine which is a metabolite can be improved significantly, the average yield of the isoleucine can be up to 36.9g / L and can be increased by 30% compared with that of the metabolite isoleucine obtained by adopting the original method, the conversion rate of the metabolite isoleucine can be increased by 2-4%, and the fermentation cycle can be shortened by 10 hours.
Owner:HENAN JULONG BIOLOGICAL ENG CO LTD
Clinical nutritional formula special for kidney dialysis and preparation method thereof
InactiveCN108651988AImprove cleanlinessRepair functionVitamin food ingredientsLipidic food ingredientsOxygenKidney
The invention provides a clinical nutritional formula special for kidney dialysis. The clinical nutritional formula special for kidney dialysis comprises the following components in parts by weight: 15-25 parts of protein, 8-12 parts of fat, 50-54 parts of carbohydrate, 3-5 parts of dietary fiber, 0.3-0.6 part of macro-elements, 0.01-0.05 part of trace elements, 0.005-0.02 part of fat-soluble vitamin, 0.01-0.2 part of water-soluble vitamin, 0.05-1 part of dietary essence, 0.05-2 parts of medicinal and edible components, 0.1-3 parts of natural plant compounds, and 0.005-2 parts of new resourcefood; and the invention also provides a preparation method of the clinical nutritional formula. The clinical nutritional formula special for kidney dialysis provided by the invention can provide balanced nutrient substances for patients with renal dialysis, and can maintain the stability of the body quality of the patient, enhance the ability of immune response and the repair function, reduce inflammation, and improve the activity of scavenging oxygen free radicals and the endothelial cell function.
Owner:上海奥医生物医药科技有限公司
Scientific weight losing fully nutritional powder composition having satiety
InactiveCN107440095AClearing away heat and nourishing the lungsHas a preventive effectVitamin food ingredientsNatural extract food ingredientsIntestinal structureAdditive ingredient
The present invention discloses a scientific weight losing fully nutritional powder composition having satiety and belongs to the field of special dietary food processing. The composition is characterized by comprising the following components in percentages by mass: oat dietary fibers, plantago ovate seed shell powder, a garcinia cambogia fruit extract, a green coffee bean extract, sodium caseinate and mogrosides, and is also prepared by mixing the following raw materials: soybean protein isolate, plant fat powder, compound vitamins and compound minerals. By adding the oat dietary fibers, plantago ovate seed shells, sodium caseinate and mogrosides, the composition reaches effects of promoting satiety, moistening intestines and relaxing bowels. By adding the garcinia cambogia fruit extract and coffee bean extract, the composition has effects of inhibiting appetite and promoting fat metabolism. By adding the soybean protein isolate, plant fat powder, compound vitamins and compound minerals, the composition can supplement body with proteins, fats, vitamins and minerals, enables the body to reach purposes of being health and losing weight, and is especially suitable for populations with obesity and overweight.
Owner:MEILU BIOTECH CO LTD
Method for promoting germination of cercidiphyllum japonicum seeds and increasing germination rate of cercidiphyllum japonicum seeds
InactiveCN103283340AHigh activityPromote germinationSeed and root treatmentBiotechnologyStratification (seeds)
The invention discloses a method for promoting germination of cercidiphyllum japonicum seeds and increasing germination rate of the cercidiphyllum japonicum seeds. The method mainly comprises the steps of: selecting the cercidiphyllum japonicum seeds, disinfecting the cercidiphyllum japonicum seeds, laser-treating, breaking the dormancy of the cercidiphyllum japonicum seeds, germinating the cercidiphyllum japonicum seeds, and transplanting seedlings. According to the method, by comprehensively utilizing all aspects of laser treatment, vitriolization, hormone treatment, epilimnion stratification treatment, temperature and illumination intensity control, culture matrix selection and the like, the germination of the cercidiphyllum japonicum seeds is promoted, the germination rate is high; meanwhile, cercidiphyllum japonicum seed seedlings obtained by using the method are developed in root systems, good in growth vigour, high in speed and high in survival rate.
Owner:常熟市润丰农业有限公司
Virus-free in situ and alcohol fermentation method of composite bacteria for lignocellulose hydrolysis product
The present invention relates to an in-situ detoxification ethanol fermentation method of lignocellulose hydrolysate, which respectively inoculates Y5 and CBS6054 into fermentation culture medium containing dilute acid lignocellulose hydrolysate to carry out in-situ detoxification alcoholic fermentation. The method can efficiently metabolize glucose and xylose in the dilute acid lignocellulose hydrolysate to produce ethanol, and rapidly metabolize furfural and 5-hydroxymethylfurfural. The yield of ethanol is 0.44g / g, reaching 87.5 percent of the theoretical value. Moreover, any detoxification processing is not needed, the requirement on equipment is low, the operation is convenient, and the cost is low.
Owner:CAPITAL NORMAL UNIVERSITY
High-energy instant food
The invention provides a high-energy instant food which is prepared from the following raw materials in parts by weight: 10 to 15 parts of grain flour, 5 to 40 parts of soybean flour, 5 to 40 parts of cooked whole grain, 5 to 20 parts of vegetable oil, 2 to 15 parts of syrup, 1 to 5 parts of sucrose, 1 to 5 parts of capric glyceride, 0.5 to 2 parts of soybean lecithin, 0.2 to 5 parts of vegetable powder, 0.1 to 2 part of salt, 0.1 to 0.5 part of compound vitamin, 0.1 to 0.5 part of compound mineral, 0.1 to 0.5 part of methionine, 0.1 to 0.3 part of L-carnitine and 0.1 to 0.5 part of edible essence. The product has the characteristics of high energy (more than 5kilocalories / gram), good taste, comprehensive nutrition, oxygen deficiency resistance, rapid, long-term and continuous energy supply and the like.
Owner:XIAN LI BANG CLINICAL NUTRITION CO LTD
Paramagnetic metal complex and synthetic method and application thereof
ActiveCN102336838AIncreased toxicityShort retention timeNMR/MRI constrast preparationsDiseaseSolubility
The invention provides a paramagnetic metal complex and a synthetic method and application thereof. The paramagnetic metal complex is an arabinogalactan-modified 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacethyl paramagnetic metal complex. A magnetic resonance imaging contrast agent prepared from the paramagnetic metal complex has high stability, water solubility and relaxation rate and is targeted to liver and kidney, so that targeted imaging is realized, and the imaging contrast and definition are improved. The paramagnetic metal complex has a good effect on raising the early diagnosis levels of diseases of liver and kidney organs, is about 2 times the relaxation rate of dotarem, has very long targeted radiography imaging time, can be easily prepared into a solution with required concentration for intravenous injection, is suitable for sterilizing and disinfecting with a hot pressing method, can be selectively identified by an asialoglycoprotein receptor on a liver parenchyma surface, and has high selectivity on livers of human beings or other mammals.
Owner:CHANGZHOU INST OF ENERGY STORAGE MATERIALS &DEVICES
Method for sectional regulation and control for continuous strain culture
PendingCN109504629AShorten the preparation processSimple production processBacteriaMicroorganism based processesNutrientContinuous fermentation
The invention discloses a method for sectional regulation and control for continuous strain culture. By adopting the method, nutrient substances are continuously replenished into a fermentation liquidto maintain strain metabolism, and at the same time, the fermentation liquid is continuously led out and is fed into a serial fermentation tank for further fermentation; to increase the strain metabolism velocity, parameters such as dissolved oxygen, pH values and replenished material constitution are respectively regulated and controlled at different stages. By adopting the method, the times ofstrain culture and equipment cleaning are reduced, the production process can be simplified, and the fermentation cost can be reduced. In addition, due to sectional regulation and control on the fermentation process, the yield of rhamnolipid can be increased, the fermentation production efficiency can be improved, the product batch stability can be improved, and the method is easily applied to industrial production.
Owner:WANHUA CHEM GRP CO LTD
Heterocyclic indene derivatives and their radioisotope labeled compounds for imaging beta-amyloid deposition
InactiveUS20080299041A1Easy to radiolabelHigh binding affinityNervous disorderOrganic chemistryCombinatorial chemistryIsotope
The invention is directed to heterocyclic indene derivatives useful for β-amyloid plaque imaging, their radiolabeled compounds and their preparation methods. The compounds of the invention are easily labeled with radioisotopes and have high affinities to β-amyloid depositions, thus they facilitate diagnosis of Alzheimer's disease by imaging the distribution of β-amyloid depositions.
Owner:SEOUL NAT UNIV R&DB FOUND
Application of paeonol for preventing and treating fatty liver disease
InactiveCN1919187AEstablish the basis for treatmentLow priceDigestive systemPharmaceutical delivery mechanismFatty liverFluid infusion
Disclosed is the use of paeonol in preparing medicament for the prevention or treatment of fatty liver, and also the use of medicinal combination preparation of paeonol with medicinal carrying agent in preparing medicaments for the prevention and treatment of fatty liver disease, the dose forms of the medicament include soft capsules, drop pills, pills, powders, tablets, capsules, granules, injections, fluid infusions, freeze-dried powders for injection, suppositories, film agents, tiny capsules, tincture, syrup, oral liquids and other pharmaceutically acceptable dose forms.
Owner:戴敏
Corn oil containing medium chain fatty acid ester and preparation method thereof
ActiveCN101919450AFast metabolismReduced health functionEdible oils/fats production/working-upLong chain fatty acidLong-chain fatty acid binding
The invention belongs to the technical field of the preparation of corn oil, in particular to the corn oil containing a medium chain fatty acid ester and a preparation method thereof. The weight percentage of the medium chain fatty acid ester in the corn oil containing the medium chain fatty acid ester is between 25 and 40 percent. In the corn oil containing the medium chain fatty acid ester obtained by ester exchange technology, medium chain fatty acid is successfully combined with long-chain fatty acid, so that a product has a health-care function of reducing the accumulation of fat and hasthe characteristic of usability for cooking delicious food like ordinary edible oil.
Owner:SHANDONG SANXING CORN IND SCI CO LTD
Total matrine and use of its preparation in zoopharmacy
InactiveCN1579397AHigh purityEasy to produceAntibacterial agentsOrganic active ingredientsMatrineVeterinary Drugs
The invention relates to application of matridine in curing flow and animals' bacteria infection, the matridine is extracted from the soybean plants.
Owner:LUZHOU ECOLOGICAL SCI TECH SHANDONG
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