174 results about "Antipruritic Effect" patented technology

It is intended to provide antipruritics (drugs to control itching, antiitch agents and drugs to stop itching). It is found out that a compound having an agonistic activity to the cannabinoid receptor shows an antipruritics effect.

An antipruritic composition and a wound-healing-promoting composition which comprise Sasa albo-marginata (Bambooseae Sasa) extract in an amount ranging from 1 to 10% by mass as expressed in terms of the solid content thereof. The composition of the present invention comprises the Sasa albo-marginata extract in a concentration substantially higher than that observed for the conventional composition and accordingly, the composition shows high antipruritic effect against skin diseases such as atopy, which have conventionally been considered to be difficult to treat and / or alleviate and the composition likewise shows an excellent wound-healing-promoting effect.

The invention relates to high-effective mosquito repelling liquid medicine which is characterized by comprising the following components by weight percent: 2%-7% of N, N-Diethyl-m-toluamide, 0.2%-2% of glycyrrhiza extract (0.1%-90% of glycyrrhizinic acid or glycyrrhetinic acid or physiologically acceptable salt thereof), 0.2%-2% of flavescens extract (0%-90% of matrine or oxymatrine or physiologically acceptable salt thereof), 0%-50% of menthol or borneol and 0.01%-2% of plant essential oil. The high-effective mosquito repelling liquid medicine is the hormone-free preparation made of pure Chinese herbal medicine for external application and is prepared by uniquely combining the high-effective repellent with the components having the anti-inflammatory, the antibacterial and the antipruritic effect, thereby being innovative. The high-effective mosquito repelling liquid medicine of the invention has the function of repelling the mosquito, relieving the itching, refreshing the consciousness and protecting the skin from the insect bite and can repel the mosquito for 5-7 hours. The high-effective mosquito repelling liquid medicine of the invention is non-toxic to the skin and mucous membrane, can not cause the allergic reaction and has higher stability.

The invention discloses a bacteriostatic lotion and a preparation method thereof. The bacteriostatic lotion comprises the following raw materials in parts by weight: 0.8-1.6 parts of chlorhexidine acetate (CA), 1.5-2.5 parts of fructus cnidii extraction liquid, 1.5-2.5 parts of khosam extraction liquid, 1.5-2.5 parts of phellodendron extraction liquid, 4-8 parts of polyoxyl stearate (40) (S-40), 1-5 parts of Poloxamer (P-188), 0.5-1.5 parts of borneol, 0.5-1.5 parts of menthol, 1.5-2.5 parts of eucalyptus oil, 20-30 parts of 95% ethanol, 10-15 parts of polyethenoxy ether (AE09), 2-5 parts of 1% cacao brown, 0.5-1.5 parts of 20% glacial acetic acid solution, 15-25 parts of glycerin and 900-1000 parts of purified water. The bacteriostatic lotion has simple process control, good bacteriostatic and antipruritic effect and low cost.

An innovative therapy of various dermatitis such as atopic dermatitis can be attained by antibacterial, antiviral, antiallergic, antiphlogistic, blood-circulation accelerating, antifungal, sterilizing, anti-itching actions by the above respective ingredients, accelerating action for permeation of pharmacologically active ingredients to deep region of skin by Cnidii Rhizoma and Japanese Angelicae Root, accelerating action for keratinization in the diseased part by salicylic acid and resorcinol.

The invention aims to find out a novel pharmacological effect (medical use) of cannabinoid. Since cannabinoid agonists such as palmidrol and anandamide have an excellent antipruritic effect, they are useful as an agent for treating any types of pruritus such as ocular pruritus, skin pruritus and systemic pruritus.

The invention discloses a Chinese medicinal ointment with antibacterial and antipruritic effects and a preparation method thereof. The Chinese medicinal ointment comprises the following raw materials: amur corktree bark, lightyellow sophora root, common ducksmeat herb, aloe, argy wormwood leaf, fineleaf schizonepeta herb, borneol and the like. The invention also discloses a preparation method forthe Chinese medicinal ointment, which comprises the following steps: preparing a water phase from the amur corktree bark, the lightyellow sophora root, the common ducksmeat herb and the aloe; collecting volatile oil from the argy wormwood leaf and the fineleaf schizonepeta herb; grinding the borneol into fine powder; preparing an oil phase from cetyl alcohol, vaseline and glycerin; and preparing the ointment by normal working procedures. When the Chinese medicinal ointment is prepared, a water decoction heat filter method and a steam distillation method are respectively adopted to make effective medicaments give full play. When used, the Chinese medicinal ointment has the characteristics that the medicaments are directly acted on disease positions; and the response is quick. The ointment of the invention has good antibacterial, anti-inflammatory and antipruritic effects and is in a dose-response relationship. The long-term toxicity research proves that the Chinese medicinal ointment is safe.

The invention discloses an anti-dandruff agent composition, which consists of ZPT and IPBC with weight rate between 1: 10 and 100: 0. 1, wherein the composition can be allocated with each component in the shampoo or hair nourishing liquid to improve antipruritic effect and modify the opsonization of the shampoo.

The invention discloses a bactericidal odor removing agent in the chemical mixture agent field, and is characterized by comprising the components, in percentage by weight: (A) 0.25 to 5% of an organic silicon quaternary ammonium salt; (B) 0.1 to 2% of an organic silicon coupling agent; (C) 0.2 to 2% of a stabilizing agent; and (D) the balance being deionized water. The bactericidal odor removing agent has antibacterial, mildewproof, odor-removing and deodorant effects, has lastingly bacteriostatic effect and widely bacteriostatic range, simultaneously is safe and reliable for any product, and does not pollute the environment. The organic silicon quaternary ammonium salt has bactericidal and bacteriostatic effects, and non-toxic, gentle, soft and smooth properties of the organic silicon quaternary ammonium salt to human bodies are utilized, so the bactericidal odor removing agent is prepared into a spray medicament form, is used for disinfectant and bactericidal treatment of various traumatic infections and skin infections, can have rapidly bactericidal antipruritic effect for the various skin infections, and can kill bacteria and inhibit bacterial activity.

An antipruritic composition and a wound-healing-promoting composition which comprise Sasa albo-marginata (13ambooseae Sasa) extract in an amount ranging from 1 to 10% by mass as expressed in terms of the solid content thereof. The composition of the present invention comprises the Sasa albo-marginata extract in a concentration substantially higher than that observed for the conventional composition and accordingly, the composition shows high antipruritic effect against skin diseases such as atopy, which have conventionally been considered to be difficult to treat and / or alleviate and the composition likewise shows an excellent wound-healing-promoting effect.

The invention relates to relieving itching condensation and a preparing method thereof. The relieving itching condensation is used for discomfort caused by mosquito bite, shrimp and crab allergies and the like. The relieving itching condensation is composed of, by weight, 3%-5% hydroxyethyl cellulose or carboxymethyl cellulose, 1%-2% natural anti-anaphylaxis factors, 1%-5% herba manthae heplocalycis and the balance purified water. By means of the relieving itching condensation, as for the discomfort caused by mosquito bite, hrimp and crab diver allergies and the like, the relieving itching effect can be achieved, a side effect is avoided, and the relieving itching condensation is applicable to various kinds of people.

The invention belongs to the field of cosmetics, in particular to an antidandruff and antipruritic scalp essence and a preparation method thereof. A composition includes the following components: hexamidine diisethionate and a traditional Chinese medicine extract. The traditional Chinese medicine extract includes a gentian extract. The scalp essence prepared from the composition of the invention has good solubility and also has good antidandruff and antipruritic effects.

The present invention relates to an antipruritic agent comprising a nociceptin antagonist as an active ingredient. The nociceptin antagonist can be used as a preventive or remedy for diseases associated with itching (for example, atopic dermatitis and urticaria), local pruritus cutaneous caused by insect excretion and secretion, nodular prurigo, kidney dialysis, diabetes, blood disease, liver disease, kidney disease, incretion and metabolic disorder, viscera malignant tumor, hyperthyroidism, autoimmune disease, multiple sclerosis, neurologic disease, psychoneurosis, allergic conjunctivitis, spring catarrh, atopic keratoconjunctivitis, or itching caused by excess use of laxuries and drugs because it has excellent scrtaching behavior suppressing effect, that is, antiitching effect and antipruritic effect.

The invention relates to a Yao medicine external use lotion having an itch relieving effect, and a preparation method thereof, and discloses an external use traditional Chinese medicinal product in Yao people secret recipes, for treating various skin pruritus and other sub-health symptoms. The lotion is mainly prepared from Ilex rotunda Thunb., Rhus chinensis, Climbing Groundsel Herb, Leaf of Xanthium sibiricum Patrin., Herba Lycopi, Rhamnus crenata, Perfoliote Knotweed Herb, Andrographis paniculata, Zanthoxylum nitidum, Ovateleaf Holly Bark, silvervine, Indosasa glabrata Chu et Chao var. albohispidula, Chinese mahonia, Rhizoma Polygoni Cuspidati and other natural unique rare medicinal materials according to Yao people ancient prescription. The lotion has good heat clearing, detoxifying, bacterium preventing, toxin dispelling and itch relieving effects, and is suitable for being used by various skin pruritus patients.

The invention provides gynecological antibacterial repair gel and a preparation method thereof; the gynecological antibacterial repair gel is prepared from, by weight, 1-10% of gel, 0.01-6% of an antibacterial agent, 0.1-6% of bioactive silicon, 2-20% of nursing components, 0.1-15% of a dispersant, 0.1-1% of a pH adjuster, and the balance of water; the gynecological antibacterial repair gel has excellent antibacterial property, good biocompatibility and good anti-inflammation and antipruritic effects, has a certain wound repairing effect, and can be used for treating gynecological diseases, such as vaginitis and cervicitis.

The invention relates to a formula for preparing an anti-eczema dermatitis product and the preparation method thereof. The invention adopts dexamethasone, menthol, phenol and boric acid compatibly for external use for the first time and provides an anti-eczema dermatitis product which also has multiple prevention functions of anti-allergy, anti-pruritus, anti-infection, and the like; the formula has the advantages of remarkable and quick antipruritic effect, strong bacteriostasis, small toxic side effect, and positive curative effect; ideal effect can be achieved when the anti-eczema dermatitis product is in direct use; more particularly, the tincture formula thereof has the advantages of stable property, simple preparation technology, safety and effectiveness, good feasibility, high repeatability, and controlled quality, and is suitable for the industrial production. The eczema dermatitis has diverse categories and etiologies, complicated disease diagnosis, and very high incidence and relapse rate; the anti-eczema dermatitis product of the invention has a plurality of usages, can enhance medical effect, is convenient to select in clinic, and can reduce the economic burden of the patients; therefore, with the number of dermatitis patients increasing year by year, the demand for therapeutic medication can be also increased; the formula and the preparation method thereof can produce greater social and economic benefits.

The invention discloses an acarid-killing antipruritic shampoo and a preparation process thereof, wherein the shampoo is composed of the following raw materials in mass: purified water 66-96 g, 95% ethanol 60-70g, component A 7.6-20 g, sodium methyl coconut oil acyl taurine 6-10 g, sodium lauryl sarcosinate 4-8 g, cocoamidopropyl betaine 5-8 g, ammonium lauryl alcohol polyether sulfate 3-6 g, glycerol 2-6 g, lauryl dimethyl ammonium hydroxypropyl hydrolyze wheat protein 2-5g, decyl glucoside 2-5g, cocoamide propyl PG-Dimethyl ammonium chloride phosphate 1-4g, sodium chloride 1-3 g, sodium lauryl sulfate 0.8-1.5 g, dipropylene glycol 0.8-1.5 g, linoleic acid amide propyl PG-Dimethylammonium chloride phosphate 0.5-1.5 g, guar gum hydroxypropyltrimethylammonium chloride 0.1-0.5 g, citric acid0.1-0.5 g, polyquaternary ammonium salt-100.1-0.5 g, allantoin 0.1-0.5 g, essence 0.5-0.8 g; Shampoo preparation process through a number of steps to achieve the preparation of shampoo. The shampoo of the invention has strong anti-acarid and antipruritic effects and is mild and non-irritating, and is suitable for long-term use by the general public.

Ointment for rhinitis is disclosed. The ointment includes main materials and auxiliary materials. The main materials include small centipeda herb, dahurian angelica roots, biond magnolia flower-bud, siberian cocklebur fruit, manchurian wildginger, mint and borneol, and include, by weight, 5-15 g of small centipeda herb, 8-12 g of dahurian angelica roots, 6-14 g of biond magnolia flower-bud, 10-20g of siberian cocklebur fruit, 8-12 g of manchurian wildginger, 3-7 g of and 1-7 g of borneol. The auxiliary materials include sesame oil, vaseline and qingliang oil. The ointment has antibacterial, anti-inflammatory, bacteriostatic and antipruritic effects, and has assistant improving and relieving effects for allergic rhinitis, sinusitis and various types of allergic rhinitis caused by dust mites. The ointment after long-term use can achieve a radical treatment effect and the success rate of treatment is extremely high. The sesame oil and the qingliang oil are added in the raw materials so that flavor of herbal medicines is reduced and the ointment is suitable for more people.

The invention discloses a formula and a preparation method of a body wash gel with the functions of removing acarid and relieving itching, the formula of the body wash gel is composed of the followingcomponents: A component, lauric acid, myristic acid, stearic acid, ethylene glycol distearate, potassium hydroxide, hydroxyethyl cellulose, glycerol, sodium lauryl polyether sulfate, cocoamidopropylbetaine, seaweed polysaccharide, MEC natural plant repellent, purified water, DMDM hydantoin, essence, and B component. The preparation method of the formula of the body wash gel comprises that followsteps of: a, distributing the group B into ethanol solution of a concentration of 60-70%; b, preparing component A; c, preparing a solution 1; d, preparing a solution 2; e, preparing a solution 3; f,preparing a mixed solution; and g, obtaining the body wash gel. The green herb are added, the invention can be use for a long time, and has the advantages of mild cleaning, dry after cleaning, no irritation to skin, strong anti-acarid and antipruritic effect, and safer and more reliable use.

The invention provides a natural antibacterial ointment containing an Artemisia argyi extract and a preparation method thereof. The natural plant bacteriostatic ointment mainly comprises various efficient bacteriostatic and anti-inflammatory components such as the Artemisia argyi extract, a purslane herb extract, a radix sophorae flavescentis root powder, dipotassium glycyrrhizinate, camellia seedoil, menthol, lavender essential oil and a cortex moutan extract, and the components are all natural sources, non-toxic and non-irritant; therefore, the natural plant antibacterial ointment containing the Artemisia argyi extract has obvious bacteriostatic, anti-inflammatory, analgesic and antipruritic effects, has an obvious inhibitory effect on escherichia coli and staphylococcus aureus, has a skin care effect, does not contain chemical synthetic bacteriostatic agents and preservatives, and is green, safe, non-toxic and non-irritant.

The invention provides an antidandruff and antipruritic shampoo. The antidandruff and antipruritic shampoo is prepared from the following raw materials in parts by weight: 65-70 parts of water, 18-20parts of sodium lauryl polyoxyethylene ether sulfate, 3-4 parts of cocamidopropyl betaine, 2-4 parts of a polydimethylsiloxane emulsion, 1.5-2.5 parts of cocamide MEA, 1 part of pyrithione zinc, 1 part of a soapnut extract, 0.8 part of an essence, 0.3-0.5 part of guar hydroxypropyltrimonium chloride, 0.4 part of mentha arvensis leaf oil, 0.2-0.4 part of piroctone olamine, 0.2-0.3 part of sodium styrene / acrylates copolymer, 0.2 part of DMDM hydantoin and 0.2 part of sodium chloride. The antidandruff and antipruritic shampoo has antidandruff and antipruritic effects and further has a conditioning function, hair can be protected while washed, poison and stimulation are avoided, and a production process is simple.

The invention provides an externally applied pharmaceutical composition containing a squalene epoxidase inhibitor and an H1 receptor blocker, which aims at overcoming the defect that the antipruritic effect of the squalene epoxidase inhibitor is non-obvious when being used for treating fungal infection. The pharmaceutical composition provided by the invention has the characteristics of killing fungi and realizing synergistic anti-inflammation and synergistic antipruritic effect, and can significantly improve the symptoms of superficial skin fungal infection.

The invention provides a natural shampoo, which is composed of the following parts by weight: 15-25 parts of fermented rice washing water, 2-8 parts of soybean saponin, 2-5 parts of tea seed extract, and 2-5 parts of rosemary extract Herbs: 15‑35 parts, aloe vera oil: 10‑20 parts, sesame leaves: 35‑45 parts, licorice extract: 6‑8 parts, citric acid: 4‑6 parts, wampum fruit leaves: 6‑8 parts, Grain fermented water: 20‑25 parts, cereal protein: 6‑8 parts, grain B group: 0.08‑5 parts, amino acid: 1‑3 parts, vitamin A: 1‑2 parts, trace elements: 3‑6 parts, Edible enzyme: 12-15 parts; the shampoo prepared by the present invention can alleviate phenomena such as scalp allergy, itching, oily appearance, excessive dandruff and prevent hair loss, has no toxic and side effects, and is especially suitable for pregnant women, children and those with skin allergies; In addition, tea seed extract, rosemary extract, and licorice extract can enhance hair quality, and long-term use can make hair black, shiny, and uniform in thickness; rice fermented water, rice protein, and grain B family, amino acids, and vitamin A can make hair more supple and nutritious.

The invention discloses a scurf dispelling and antipruritic skin care health perfumed soap, which consists of perfumed soap genuine, additives and hair and skin care agents, wherein, the additives comprise borax, anhydrous sodium sulphate and plum borneol, and the hair and skin care agent is polymeric quaternary ammonium salt-47 or water-soluble silicon oil; the weight percentage proportion of the components are: 30 to 63 percent of the perfumed soap genuine, 20 to 45 percent of the borax, 10 to 30 percent of the anhydrous sodium sulphate, 1 to 10 percent of the plum borneol and 5 to 10 percent of the skin care agent. The perfumed soap genuine of the invention can clean and decontaminate, the hair and the skin can be protected by the hair and skin care agents, and fungi and bacteria breeding can be inhibited destroyed by additives, with the functions of sanitizing and sterilization. The invention can destroy the source of the scurf, beriberi and pruritus, and the strong scurf dispelling and quick antipruritic effects can be achieved; the skin diseases caused by bacteria, fungi and viruses can be prevented and cured, and the perfumed soap can act as a supplementary treatment on skin diseases.

The invention discloses an antibacterial environment-friendly diaper with high hygroscopicity. According to the diaper, by utilizing physicochemical properties of konjac glucomannan, including high viscosity, high hygroscopicity, rapid expansion and the like, a nanofiber membrane is prepared through electrostatic spinning, so that the bioavailability and the water binding capacity of the konjac glucomannan are improved; the konjac glucomannan nanofiber membrane / base anti-reverse osmosis layer has a sufficient space structure, and is breathable and antibacterial, and meanwhile, is also cool, and has a prickly heat removal effect and breathability. The konjac glucomannan has stable performance, and the prepared konjac glucomannan environment-friendly diaper has high bioavailability, good antibacterial performance and high hydroscopicity. According to the konjac glucomannan environment-friendly diaper disclosed by the invention, menthol therein acts on the skin or mucous membranes, and has the effects of being cool and relieving itching; cortex phellodendri and flos lonicerae can enhance immunity, diminish inflammation, relieve internal heat, stop bleeding and the like; and musk is anti-inflammatory and bacteriostatic. The diaper has the advantages of being convenient in material taking and low in cost, having a good antibacterial property, a simple preparation process, being poisonless and harmless, having biodegradability and good bioavailability.

The invention relates to a preparation method of a bacteriostatic ointment for treating the itching skin diseases, and belongs to the technical field of the medicine for treating the itching skin diseases. The preparation method comprises the following components in parts by weight: 4-8 parts of honeysuckle, 3-6 parts of rhubarb, 4-8 parts of wild chrysanthemum flower, 3-5 parts of cortex pseudolaricis, 2-4 parts of radix sophorae flavescentis and 2-4 parts of fructus cnidii, 2-4 parts of radix stemonae, 2-4 parts of Chinese angelica, 3-6 parts of broom cypress fruit, 3-5 parts of duckweed, 4-6 parts of bryophylli, 3-6 parts of nano silver, 20-40 parts of sesame oil, 2-5 parts of chlorhexidine acetate, 1-2 parts of sodium dodecyl sulfate, 2-5 parts of vitamin E oil and 1-3 parts of glyceryl monostearate. The product has the effects of clearing heat, dispelling pathogenic wind, promoting blood circulation, removing blood stasis and relieving itching, and has good antibacterial and antipruritic effects on itching skin, and has remarkable curative effect.

The invention discloses a hair conditioner and a production device thereof. The hair conditioner is characterized by comprising the following steps: firstly, mixing more than one of tangerine skin, orange peel and flavedo with water according to the weight ratio of (1:8) to (1:10); boiling a mixture obtained from the former step in a pot for 5-15 minutes; cooling to room temperature, and taking out the pericarps; filtering out impurities in a liquid; mixing filtrate obtained from the former step with 95% edible ethyl alcohol and stirring for 5-15 minutes and standing for 5-8 hours, so that the upper layer liquid is the hair conditioner, and the weight dosage ratio of the 95% edible ethyl alcohol to the filter liquor is (2-2.5) to 1. Compared with the prior art, the hair conditioner has the advantages that an extracting solution has biological activity, the nourishing hair care effect is obvious, and antipruritic effect can be realized.

The invention discloses an external medicament for treating bacterial vaginosis and colpitis mycotica. The external medicament is a medicament prepared from Chinese medicinal raw materials including 35-70 parts by weight of amur corktree bark, 30-60 parts by weight of lightyellow sophora root, 30-60 parts by weight of cortex ailanthi, 20-40 parts by weight of polygonum aviculare, 10-35 parts by weight of selinum japenious seed and 1-2.5 parts by weight of borneol according to the conventional preparation method. As proved by a pharmacodynamic test, the medicament has a remarkable in-vitro antibacterial action, and can be used for effectively killing and suppressing common pathogenic bacteria of reproductive tract infection; the medicament has a remarkable treatment effect on rabbit colpitis mycotica; compared with a model control group, a medicament group has the advantages: the vagina cleanliness and curative ratio are increased remarkably, and the pathological feature of rabbit colpitis mycotica can be improved remarkably; the medicament has a remarkable anti-inflammatory effect, and can be used for remarkably relieving dimethyl benzene-caused mouse auricle inflammation, suppressing the formation of mouse granuloma and reducing the mouse abdominal cavity capillary permeability; and the medicament has a certain itching relieving effect.

The invention relates to an application of prinsepia utilis royle oil in the products preparation for treating mosquito bites; the product which is prepared with prinsepia utilis royle has good antipruritic and detumescent effect; the product can be made into emulsions or oils to achieve the antipruritic effect and detumescence effect.

The present invention relates to an antipruritic agent comprising a nociceptin antagonist as an active ingredient. The nociceptin antagonist can be used as a preventive or remedy for diseases associated with itching (for example, atopic dermatitis and urticaria), local pruritus cutaneous caused by insect excretion and secretion, nodular prurigo, kidney dialysis, diabetes, blood disease, liver disease, kidney disease, incretion and metabolic disorder, viscera malignant tumor, hyperthyroidism, autoimmune disease, multiple sclerosis, neurologic disease, psychoneurosis, allergic conjunctivitis, spring catarrh, atopic keratoconjunctivitis, or itching caused by excess use of laxuries and drugs because it has excellent scratching behavior suppressing effect, that is, antiitching effect and antipruritic effect.