7 results about "Arterial Embolization" patented technology

The invention discloses application of a chemotherapy drug-microalgae embolization agent in preparation of a drug for treating tumors through arterial embolization, belongs to the technical field of biological medicine, and particularly relates to the technical field of biological medicine manufacturing, and the chemotherapy drug-microalgae embolization agent is composed of a pharmacologically effective amount of chemotherapy drug and microalgae, the chemotherapeutic drug is electropositive in a physiological environment and is combined with the microalgae through electrostatic adsorption, and preferably, the mass ratio of the microalgae to the chemotherapeutic drug is 1: (0.1-10). The chemotherapy drug-microalgae embolization agent has pH responsiveness when releasing chemotherapy drugs, and can improve an acidic tumor microenvironment, so that the antitumor effect is synergistically enhanced; the chemotherapeutic drug, namely the microalgae embolization agent, also has good biocompatibility and biodegradability. The chemotherapeutic drug-loaded microalgae provided by the invention provides clinical transformation potential for malignant tumor treatment.

The utility model provides a kind of patient gown for hepatic artery embolism patient, comprising: cardigan, waist of inside of cardigan is provided with waist support structure;Compression band assembly, compression band assembly includes threaded connecting rod structure, fixed structure being rotatably arranged on threaded connecting rod structure and knob structure and abutting structure being fixedly connected at both ends of threaded connecting rod structure, between knob structure and fixed structure, it is also provided with the fastening band for binding patient femoral artery, fastening band is sleeved on threaded connecting rod structure, it is also sleeved with the connecting band for connecting waist support structure on threaded connecting rod structure, connecting band is arranged between fastening band and knob structure.

To provide a material for embolic arterial intervention (embolotherapy or arterial embolotherapy) and a method for preparing the material.SOLUTION: Radiopaque, bioresorbable spherical microparticles for embolization or vascular occlusion therapy are provided which comprise a copolymer of an iodo-containing, halogenated phenyl-containing unit, such as an iodinated desaminotyrosine derivative, and a rubbery component such as polyethylene glycol (PEG), polycaprolactone (PCL), polytetramethylene oxide (PTMO) or polytrimethylene carbonate (PTMC). The provided microbeads can further contain or be coated with a therapeutic agent, such as paclitaxel, for targeted delivery of the therapeutic agent.SELECTED DRAWING: Figure 3

Compositions and methods for treating one or more symptoms associated with vaginal atrophy or discomfort are disclosed. The compositions include an effective amount of one or more of the active agents selected from pectin (P), hyaluronic acid (HA), and collagen (Cg), in a pharmaceutically acceptable carrier, for vaginal delivery. The disclosed compositions are useful in treating one or more symptoms associated with vaginal atrophy. Example subjects include postmenopausal women or premenopausal women who experience these symptoms as a result of breastfeeding, intensive vaginal douching, cigarette smoking, autoimmune conditions such as Sjogren's syndrome, pathologic conditions such as diabetes, premature ovarian insufficiency, bilateral oophorectomy, ovarian failure due to radiation or arterial embolization, hypothalamic-pituitary disorders. Additionally, the disclosed compositions are useful in generally alleviating vaginal discomfort such as pH imbalance, vaginal dryness, burning, itching, vaginal discomfort, pain and burning when urinating, dyspareunia (painful sex), and spotting during intercourse.

The invention discloses a coagulant-loaded embolism microsphere as well as a preparation method and application thereof, the embolism microsphere is prepared through microfluidic and free radical polymerization technologies, and the coagulant-loaded embolism microsphere has a wide application prospect in the fields of arterial embolism treatment, tumor vascular infarction and the like. The embolism microspheres have the characteristics of uniform size, efficient entrapment and continuous release of the coagulant, and can effectively promote fibrinogen to generate fibrin and accelerate coagulation of rabbit blood. Besides, the thrombin-loaded embolism microspheres can obviously induce tumor artery occlusion, and obvious blood clots are formed in far-end blood vessels, so that the growth of rabbit in-situ VX2 tumors is effectively inhibited. The embolism microsphere carrying the coagulant has the advantages of being high in safety, easy and convenient to prepare, good in embolism effect and the like, and efficient entrapment and controllable release of thrombin can be achieved. In the aspects of liver cancer transarterial embolism and tumor vascular infarction treatment, the technology has great transformation potential and is expected to promote the development of vascular embolism agents.

The invention discloses degradable and elastic embolism microspheres with uniform particle size as well as a preparation method and application of the embolism microspheres, and belongs to the technical field of biomedical polymer materials. Crosslinkable micromolecules with an acrylic acid structure are connected to the macromolecules in a covalent bond mode, and the functionalized macromolecules are formed. The embolism microspheres are prepared through microfluidic and free radical polymerization technologies, and the microspheres prepared by the method have good application prospects in the field of arterial embolism treatment. According to the embolism microsphere, the embolism microsphere with the uniform particle size is prepared through the microfluidic technology, the generation operation is further simplified, the production cost is reduced, and the production process is more economical and environmentally friendly. The embolism microsphere disclosed by the invention is high in safety, convenient to prepare, good in dispersity, relatively good in elasticity and good in embolism effect, has relatively large transformation potential in the aspect of transarterial embolism treatment, and is expected to assist the development of vascular embolism agents.