The utility model discloses a three-dimensional laser washing device. The three-dimensional laser washing device comprises a pulsed laser with indicating red light and a control system of the same pulsed laser, a beam spread collimation optical system, a two-dimensional optical scanning galvanometer and a controller of the same two-dimensional optical scanning galvanometer, a focusing position regulator and a displacement controller. The focusing position regulator consists of a focusing lens, a filter, a microscopic imaging lens, a CCD (Charge Coupled Device) and a processor, wherein the focusing lens is fixed with the microscopic imaging lens, the indicating red light of the pulsed laser reflects on the sample and images on the CCD (Charge Coupled Device), the microscopic imaging lens moves longitudinally to find a position where the contrast ratio is the highest and the image edge is the clearest, the position is a focus position of the focusing lens, and the three-dimensional laser washing device consists of the two-dimensional scanning galvanometer and the focusing lens. The three-dimensional laser washing device makes full use of the two-dimensional laser washing device which is based on the optical galvanometer scanning system, presetting the surface shape of the washing material is not required before cleaning, thereby having the advantages of being wide in application, simple in structure, good in stability, easy to debug, and the like.