222 results about "MICRO MIXER" patented technology

An array of airfoil-shaped micro-mixers that enhances fluid mixing within permeable membrane channels, such as used in reverse-osmosis filtration units, while minimizing additional pressure drop. The enhanced mixing reduces fouling of the membrane surfaces. The airfoil-shaped micro-mixer can also be coated with or comprised of biofouling-resistant (biocidal/germicidal) ingredients.

The invention relates to a continuous flow micro-reactor for medicine and fine chemical production and preparation and application thereof. The invention belongs to the technical field of the micro-reactor and preparation and application thereof. The reactor device consists of a liquor storage tank, a constant flow pump, a micro-mixer, serpentiform double helix capillary reaction pipes, an optical detector, a constant temperature bath and a connecting duct. The continuous flow micro-reactor is capable of making a reactant move back and forth continuously and spirally in the internal and external path coiled reaction pipes, thereby avoiding the phenomenon of local overheating for the reaction in the prior reactor vessel. The invention also provides a preparation method for the reactor and a method for synthesizing chalcone compounds through the reactor. The continuous flow micro-reactor has the advantages of compact structure, simple preparation, convenient use, high reaction efficiency, low power consumption, little pollution, and the like. The continuous flow micro-reactor can carry out continuous production and on-line tracking of the reaction process and has bright market prospect.

A micro-mixer 100 having a body in which there is disposed a micro-mixing chamber for mixing liquid. Micro-channels 108 extend from an external surface of the body of the micro-mixer 100 to the micro-mixing chamber 102 and define passageways for supplying liquid into the micro-mixing chamber 102. The micro-mixer 100 also has an electrical circuit that includes an electrical pulse generator that is connected to two or more spaced electrical heating elements 104 located in the mixing chamber 102 that receive electrical pulses from the pulse generator. In use, electrical pulses received by the heating elements 104 cause the heating elements to heat liquid in the mixing chamber in regions locally of each of the heating elements and thereby generating a vapour bubble which will, in turn, cause turbulence and mixing of liquid within the micro-mixing chamber.

The invention discloses an S-type passive micro-mixer in the microfluid mixing field, which comprises an upper cover plate and a mixing plate bonded together in an up-and-down manner; a first fluid inlet pipe, and a second fluid inlet pipe are disposed at the left side of the mixing plate; an outlet pipe is disposed at the right side; the two fluid inlet pipes are connected together with a main channel; n contraction mixing units and n diffusion mixing units orderly connected end to end in a smooth transition manner are disposed between the main channel and the outlet pipe; the first one of the n contraction mixing units is connected with the main channel, and the last diffusion mixing unit is connected with the outlet pipe; the outline of the horizontal axis cross section of a single contraction mixing unit is formed by two logarithmic spirals of the single contraction mixing unit; the outline of the horizontal axis cross section of a single diffusion mixing unit is formed by two logarithmic spirals of the single diffusion mixing unit; all the diffusion mixing units are at the front side of the polar axis of the logarithmic spiral, and all the contraction mixing units are at the back side of the polar axis; the contact area between fluids is increased, and thus mixing is more sufficient.

The present invention relates to a method for making passive micromixer and microreactor in microfluidic chip. Said method includes the following steps: firstly, making glass mother die chip whose bottom surface and side surface have submicrostructure, utilizing glass mother plate chip to prepare all-glass chip or all-glass mixed chip whose three faces or all-channel have submicrostructure, or utilizing the process of pouring polymer to obtain the male die complementary with glass mother plate microstructure, utilizing said male die to make secondary pouring and duplication so as to obtain the chip of polymer base material with glass, mother plate structure, then further making packaging combination to obtain all-polymer mixed chip or composite chip.

A micro mixer for use in a microdevice which utilizes time-varying force fields to induce bulk fluid and/or sample component motion leading to homogenization of sample components. Time-varying force fields employed includes at least one of a physical displacement field, electrical field, pressure field or magnetic field to generate transverse forces which induce the mixing of samples within the micro mixer.

The invention belongs to the field of immunology, and particularly relates to a micro-fluidic chip according to a time-resolved fluorescent technique, a preparation method of the micro-fluidic chip and an application of the micro-fluidic chip. The micro-fluidic chip according to the time-resolved fluorescent technique comprises a sample adding area, a filtering area, a time-resolved fluorescent micro-sphere antibody or antibody compound binding area, a micro-mixer, a reaction area and a waste liquid area. According to the micro-fluidic chip, antigens or antibodies marked by time-resolved fluorescent nano-particles, light stability is strong, sensitivity is high, and interference of samples can be effectively avoided. The antigens or antibodies of a plurality of items to be detected can besimultaneously marked on the micro-fluidic chip, a plurality of items of a single sample can be simultaneously detected, efficiency is improved, and sample cost and time cost are saved. The preparation method of the micro-fluidic chip is simple, detection accuracy is high, low difference between batches and high stability are ensured, and full quantitative detection of the samples can be realized.

The invention relates to a micro-fluidic chip for multi-object quantitative detection based on magnetic particle chemiluminescence. The micro-fluidic chip is of a double-layer structure and comprises a cover plate (1) and a bottom plate (11), wherein an air pump (3), an air flow micro-channel (5), a sample adding hole (2), a sample liquid flowing channel (6), a first biomarker storage pool (4), a micro-mixer (7) and a transition area (10) on the cover plate (1) are connected in sequence. A filter (12), a reaction chamber (13), a cleaning area (14), a detection chamber (15) and a solution release channel (18) on the bottom plate (11) are connected in sequence, and the detection chamber (15) is connected with a luminous liquid storage pool (16) and a cleaning fluid storage pool (17) respectively through the solution release channel (18).

The invention discloses a method for synthesizing acyl naphthalene by using a micro-channel reactor. The method comprises the following steps: (1) preparing acylation liquid, namely adding nitrobenzene and anhydrous aluminum chloride into a reactor in a low-temperature tank, finally adding acyl chloride, and controlling the temperature in the reactor to be 0-3 DEG C; (2) preparing a feed solution,namely adding nitrobenzene and 2-methyl naphthalene into a reactor provided with a stirrer; (3) reacting, namely injecting the feed solution and the acylation liquid into a micro mixer to be mixed, and feeding into the micro-channel reactor to be reacted; (4) washing, namely enabling the product discharged from the micro-channel reactor to enter the micro mixer again so as to be washed, enablingthe mixture into the micro-channel reactor, controlling the reactor temperature to 40-50 DEG C, and performing ultrasonic oscillation outside the reactor; (5) performing reduced pressure distillation,namely separating the products obtained in the step (4), and performing vacuum decompression to 500-1000Pa so as to obtain a crude product 2-methyl-6-acyl naphthalene; and (6) recrystallizing, namelyadding the crude product obtained in the step (5) into a solvent of 50-60 DEG C, stirring and dissolving, naturally cooling and crystallizing, continuously cooling and crystallizing in an ice-water bath, and finally filtering to obtain the purified product 2-methyl-6-acyl naphthalene.

The invention discloses a method for producing thiuram disulfide as thiofide by a continuous micro-reaction system. According to the method, three processes including secondary amine-NaOH solution mixing, CS2-secondary amine condensation reaction and sodium dithiocarbamate oxidation reaction are sequentially completed by a micro-mixer and a micro-reactor which are connected in series; reaction materials are efficiently mixed by the micro-reaction device, and side reactions such as overoxidation and the like are avoided; by means of a series-integrated operation mode, production efficiency is improved, and product stability is improved. The method can be applied to production of multiple thiuram vulcanizing agents such as tetramethyl thiuram disulfide, tetraethylthiuram disulfide, tetrabutylthiuram disulfide and the like, the yield can reach 98% or higher, and product purity is high.

The invention discloses a method for preparing a sulfone compound by utilizing an electrochemical micro-channel technology. A compound I is dissolved with an acetonitrile and dichloroethane mixed solvent, and the mixture is loaded in an injector 1 after being completely dissolved; 4-methyl benzenesulfinate and electrolyte are dissolved with an acetonitrile and dichloroethane mixed solvent, and themixture is loaded into an injector 2 after being completely dissolved; the materials in the injector 1 and the materials in the syringe 2 are pumped into a micro-mixer of a micro-channel reaction device at the same time to be mixed, and the materials are completely mixed and then pumped into the electrochemical micro-channel reaction device, react under a constant current and are oxidized to obtain the sulfone compound. The method has the advantages that the method is safe and environmentally friendly, the raw materials are low in price and easy to obtain, highly toxic reactant residues are avoided, the reaction speed is high and the efficiency is high; a sulfone compound product prepared through the preparation method has the advantages of high purity, high acidification degree and the like, and is suitable for large-scale preparation.

The invention provides a continuous preparation method of nano-copper. The continuous preparation method of the nano-copper comprises the steps that a dispersing agent is dissolved in water, copper slat is added, the pH is adjusted, and then a copper slat dispersion solution is obtained; a reducing agent is dissolved in water, so that a reducing solution is obtained; the protective agent is dissolved in water, so that a protective solution is obtained; and finally, after the prepared copper slat dispersion solution, the reducing solution and the protective solution are fed into a micro-mixer to perform a reaction, the product is purified, and then nano-copper is obtained. Compared with the prior art, the continuous preparation method of the nano-copper achieves continuous preparation of the nano-copper in the manner that the dispersion solution, the reducing solution and the protective solution are independently prepared first of all, and then the three mixed solutions conduct the reaction through the micro-mixer to prepare the nanometer copper; the test conditions are gentle, purification is easy in the later period, cost is low, the micromixing time is shortened, nucleation and growth of crystals can be effectively controlled, and the prepared nano-copper particles are small and uniform in particle size; and the adopted protective agent enables nano-copper colloid to keep stable and avoid agglomeration for a long time.

A micro-mixer of a simple structure suited to form a micro-mixed liquid from two kinds of liquids A and B comprises a plurality of passage modules 7 stacked and thereby forming a multi-tiered flow passage. Each of the passage modules has a plurality of combining-dividing units 10 arranged at regular intervals. Each of the combining-dividing units has two inlets 11a, 11b and two outlets 12a, 12b. The two outlets 12a, 12b of each of the combining-dividing units in each of the stacked passage modules are connected with an inlet 11a of a combining-dividing unit and an inlet 11b of another combining-dividing unit in its immediate downstream passage module, respectively.

The invention discloses a magnetic micro-particle chemiluminescence micro-fluidic chip for quantitatively detecting a C-reaction protein. The magnetic micro-particle chemiluminescence micro-fluidic chip structurally comprises a cover plate (1) and a bottom plate (11), wherein a sampling opening (2), a sample liquid flow channel (6), a first biomarker storage pool (4), a micro-mixer (7) and a transitional area (10) on the cover plate (1) are connected in sequence; a filter (12), a reaction pool (13), a cleaning pool (14), a detection pool (15) and a solution release channel (18) on the bottom plate (11) are connected in sequence; a detection pool (15) on the bottom plate (11) is connected with a cleaning liquid storage pool (16) and a luminous liquid storage pool (17) through the solution release channel (18).

The invention publishes a micro mixer which can uniform mix gas fast and its preparation method, it involves the gas-mixing area of technology, it has joined the raised ridge in the original miniature T mixer's hybrid channel, the height of the raised ridge is consistent with the depth of the hybrid channel, the raised keel's width is half as large as hybrid channel, and the length is consistent with the width. The raised ridge distributes dividable along the both sides of the mixed channel, there has been a raised ridge's width between the neighboring raised ridge, and arranges separately. The number of the raised ridge lies on the hybrid channel's length, n= (l-3)/2l1, n expresses the raised ridge's integer, l expresses hybrid channel's length, l1 is the raised keel's length of side. The design advantages of the invention is: join the raised ridge after the hybrid channel may cause the two gases to be pressed when they flow through the raised ridge to reduce the distances between them, it can help to mix the diffusion; and because the speed increases when the gas flow through the raised ridge, it can easily produce the eddy current and increase the two contacted areas, and it is also good to mix the gases; in addition, it may produce backflow near the downstream of the raised ridge, and strengthens the two gas mixed performance.

The invention discloses a magnetic particulate chemiluminescent micro-fluidic chip for quantitatively detecting myohemoglobin. The structure of the magnetic particulate chemiluminescent micro-fluidic chip mainly comprises a cover piece (1) and a bottom piece (11), wherein an air pump (3), an airflow micro-channel (5), a sample feeding hole (2), a sample liquid flowing channel (6), a first biological marker storage tank (4), a micro-mixer (7) and a transition region (10) on the cover piece (1) are connected in sequence; a filter (12), a reaction tank (13), a washing tank (14), a detection tank (15) and a solution releasing channel (18) on the bottom piece (11) are connected in sequence; the detection tank (15) on the bottom piece (11) is connected with a washing liquid storage tank (16) and a luminescent liquid storage tank (17) through the solution releasing channel (18).

The invention discloses a planar passive micro mixer based on vortex forming structure enhanced mixing, relating to the field of micro fluid mixing in micro total analysis systems and micro fluid control chips as well as the related fields. The micro mixer is formed by connecting a straight passage, a cross passage, a first C-shaped passage and a second C-shaped passage; a passage outlet is formed at a straight passage outlet connected with the second C-shaped passage, and vortex forming structures are arranged in the C-shaped passages; and the end arm of the cross passage, which is opposite to the connected C-shaped passage, is provided with a second passage inlet (2), and the end arm vertical to the end arm is provided with a first passage inlet (2) and a third passage inlet (3) respectively. Compared with a planar passive micro mixer without the vortex forming structures, the planar passive micro mixer based on vortex forming structure enhanced mixing has the advantage of obviously enhancing the mixing strength of the micro fluid in the passages because several kinds of vortex generated by the vortex forming structures are generated in different dimensional planes respectively.

The invention discloses a preparation method of nanometer iron phosphate, which belongs to the field of chemistry and chemical engineering. The method comprises the following steps of: previously adding proper amount of ferric iron salt water solution of phosphoric acid as iron source; taking phosphate water solution as phosphorus source; using micro mixer to quickly mix the iron source with the phosphorus source to obtain iron phosphate precursor with better monodispersity in a state of nanometer particle; and using normal pressure hydrothermal method to directly process product slurry to obtain nanometer iron phosphate material with high purity and average particle size of about 100nm. The method has the advantages of simple preparation process, high production efficiency, high product purity, uniform particle size, good monodispersity and easy industrial amplification.

The invention discloses a multi-material micro-scale 3D printing device and printing method. The multi-material micro-scale 3D printing device comprises an electric fluid power nozzle system used for mixing and printing various materials. The nozzle system comprise a feeding device, a micro-mixing device, ultraviolet light curing lights and a micro-nozzle. The feeding device is provided with a plurality of micro-injection pumps and feeding pipelines. A passive micro-mixer used for effectively mixing the high-viscosity-difference materials is arranged in the micro-mixing device and comprises two or more fluid inlet flow channels, a mixing flow channel and a fluid outlet flow channel. The two or more fluid inlet flow channels are connected with the feeding pipelines of the feeding device. The mixing flow channel is of a flow channel structure capable of effectively micro-mixing high-viscosity-difference fluids and other fluids. The fluid outlet flow channel is connected with the micro-nozzle. The ultraviolet light curing lights are mounted around an outlet of the micro-nozzle.

The invention relates to a method for preparing luminescent nano-particles of rare earth doped with lanthanum phosphate, comprising the following steps: preparing stock solutions including lanthanum nitrate polyol solution doped with rare earth element of Ln and polyol solution of NaH2PO4-2H2O; mixing the stock solutions in a micro mixer and heating the mixture in oil under constant temperature after the mixture enters the micro-channels, after which the mixture will react to produce polyol solution of luminescent nano-particles of rare earth doped with lanthanum phosphate; obtaining luminescence nano-particles of rare earth doped with lanthanum phosphate by extracting, washing and centrifugal separation. With simple technology and easy for batch production, the obtained nano-particles are provided with small particles, good dispersibility and fluorescence.

Static lamination micro mixer comprising at least one slotted plate having slot openings and an aperture plate having aperture slots arranged above the slotted plate.