Application and extraction method of prinsepia utilis royle polysaccharide
By extracting and applying cyperus polysaccharides, the problems of unstable efficacy and major side effects of existing psoriasis treatment methods have been solved, significantly improve psoriatic lesions, enhance skin barrier function, and have good anti-inflammatory effects.
CN119792336AInactive Publication Date: 2025-04-11FIRST AFFILIATED HOSPITAL OF KUNMING MEDICAL UNIV
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Patent Information
- Application Number
- CN202411698693.6
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-26
- Publication Date
- 2025-04-11
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Technical Problem
The existing treatment methods for psoriasis have problems with instability in efficacy and major side effects, and no effective natural ingredients are used to improve psoriatic lesions.
Method used
By extracting the cyperon polysaccharide and using 95% ethanol extraction, deionized water extraction, under-pressure concentration and alcohol precipitation, the cyperon polysaccharide was obtained and used to treat psoriatic lesions.
Benefits of technology
The pyridium fructose significantly reduces the PASI score of psoriatic lesions, reduces scales, erythema and infiltration thickening, improves skin moisture content, enhances skin barrier function, has good anti-inflammatory effects, and increases the expression of epidermal barrier-related proteins.
✦ Generated by Eureka AI based on patent content.
Abstract
The invention discloses application and an extraction method of prinsepia utilis royle polysaccharide, which comprises the following steps: extracting prinsepia utilis royle residues with 95% ethanol at 85 DEG C, filtering, extracting the residues with deionized water at 85-95 DEG C for 2-3 times, merging extracts, performing alcohol precipitation with 90%-95% ethanol at 2-6 DEG C, removing protein through a Sevage method, centrifugally collecting supernate, and freeze-drying to obtain the prinsepia utilis royle polysaccharide. And finally determining the content of the prinsepia utilis royle polysaccharide by using an anthrone-sulfuric acid colorimetric method, wherein the obtained prinsepia utilis royle polysaccharide is used for treating and improving skin lesion of psoriasis. Tests prove that prinsepia utilis royle polysaccharide can significantly improve psoriasis skin lesion, reduce inflammatory factor expression, enhance skin barrier function and increase expression of epidermal related protein, and is helpful for relieving symptoms of psoriasis patients and improving skin conditions.
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