32 results about "Rectal mucosa" patented technology

The invention relates to fatty acid stimulation of rectal mucosa initiating the process of defecation, acting as a laxative. Furthermore, the invention relates to the usage of free fatty acids, fatty acid mixtures and fatty acid extracts from marine lipids in pharmaceutical formulations such as suppositories, ointments, tablets and gelatin capsules for treatment and prevention of multiple disorders like constipation, hemorrhoids, bacterial infections (e.g. helicobacter pylori), viral infections (e.g. herpes simplex virus infections) and inflammations, as well as against fissura ani and pruritus ani.

A device for collection of exfoliated cells from the rectal mucosa comprises a hollow, cylindrical body having an inflatable and invertible flexible membrane attached to one end thereof. Applying positive pressure to inflate the membrane after the device is inserted, preferably through a rectal access tube, into the rectum causes exfoliated cells to be collected on the surface of the membrane. Before removal of the device, negative pressure is applied and the membrane, along with the collected sample of exfoliated cells, is deflated, inverted and withdrawn into the body of the device, thereby avoiding contact of the collected sample with body surfaces or the rectal access tube as the device is removed from the rectum.

The invention relates to a medical drug delivery device, in particular to a medical rectal drug delivery device with lubricating ability. The technical problem is to provide a medical rectal applicator that can relieve the patient's pain, has quick effect and good effect, and has lubricating ability. A medical rectal drug delivery device with lubricating ability, comprising: a base plate, the shape of the base plate is rectangular; a support rod, the support rod is fixedly connected to the middle part of the base plate; an installation sleeve, the installation sleeve The upper part of the support rod is symmetrically connected by bolts; the lubricating device is arranged in the mounting sleeve on one side. The present invention achieves the effect of alleviating the pain of the patient, quick effect and good effect. By directly applying the medicine to the inflamed part in the rectum, it enters the large circulation through the rapid absorption of the rectal mucosa, so that the medicine effect can be brought into full play faster. The lubricating device lubricates the liquid applicator, which can reduce the pain of the patient.

The present invention provides a device that protects the tissue in the posterior part of the introitus vaginae, i.e. the commissura posterior. The origin of perineal tear starts here when the segment is stretched to double or triple its length during delivery of the head. Tears can be more extensive into the perineal body, continue into the anal sphincter and in worse cases even through the whole perineum into the anal canal. In use the device may protect against perineal tears of the posterior vaginal wall into the mucosa, perineal skin, muscles, even more profound down to the anal sphincter muscle and into the rectum and the rectal mucosa.

The purpose of the present invention is to provide a mucosal vaccine composition that is effective and safe as a prophylactic or therapeutic drug for infections and cancer, which effectively induces a systemic immune response and mucosal immune response, and which can be administered to the oral mucosa, ocular mucosa, ear mucosa, genital mucosa, pharyngeal mucosa, respiratory mucosa, bronchial mucosa, pulmonary mucosa, gastric mucosa, intestinal mucosa, or rectal mucosa. The present invention is a mucosal vaccine composition administered to at least one mucous membrane of a person or animal, said mucous membrane being selected from the group consisting of oral mucosa, ocular mucosa, ear mucosa, genital mucosa, pharyngeal mucosa, respiratory mucosa, bronchial mucosa, pulmonary mucosa, gastric mucosa, intestinal mucosa, and rectal mucosa. The mucosal vaccine composition is characterized by including at least one type of antigen, and, as an immunostimulant, a lipopolysaccharide or a salt thereof derived from at least one gram-negative bacterium selected from the group consisting of Serratia, Leclercia, Rahnella, Acidicaldus, Acidiphilium, Acidisphaera, Acidocella, Acidomonas, Asaia, Belnapia, Craurococcus, Gluconacetobacter, Gluconobacter, Kozakia, Leahibacter, Muricoccus, Neoasaia, Oleomonas, Paracraurococcus, Rhodopila, Roseococcus, Rubritepida, Saccharibacter, Stella, Swaminathania, Teichococcus, Zavarzinia, Pseudomonas, Achromobacter, Bacillus, Methanoculleus, Methanosarcina, Clostridium, Micrococcus, Flavobacterium, Pantoea, Acetobacter, Zymomonas, Xanthomonas, and Enterobacter.

An anoscope comprises a graspable portion, arranged for being grasped by an operator, and a body, arranged for being inserted into the terminal tract of the rectum of a patient. A cavity and at least one operating window are made in the body of the anoscope. The anoscope further comprises a housing and a seat, which are comprised in the cavity of the body. The housing is arranged for containing at least one surgical instrument suitable for treating hemorrhoids and the seat is arranged for containing at least one lighting device. A method for treating a hemorrhoid in a patient comprises the following steps: a) Inserting an anoscope into the terminal tract of the rectum of the patient through the anal opening; b) Positioning the body of the anoscope in such a way that an operating window or opening of the anoscope is near a zone of rectal mucosa to be treated, positioned near the hemorrhoids; c) Positioning a surgical instrument suitable for treating hemorrhoids inside the body of the anoscope so as to reach the operating window or opening and, through the operating window or opening, reaching the zone of rectal mucosa to be treated; d) Producing a localized heat in the submucosa of the zone of rectal mucosa to be treated through the surgical instrument, such localized heat being a heat that is limited to the zone of rectal mucosa to be treated; e) Inducing a volume reduction of the hemorrhoid as a result of the localized heat produced.

The invention discloses a rectal injury discriminator, which comprises an outer bushing and an inner bushing arranged in the outer bushing, wherein one end of the outer bushing is provided with a mushroom head; the mushroom head is provided with a hole; an elastic isolation film is covered on the hole, and is provided with a punctate through hole and a cross-shaped groove which is connected with the punctate through hole; one end of the inner bushing is provided with a pipe cavity opening which is close to the mushroom heat; the other end of the inner bushing is provided with an inner bushingjoint; and the inner bushing is provided with a switch which is positioned between the pipe cavity opening and the inner bushing joint. By adopting the rectal injury discriminator, a rectal mucosa can be spread appropriately, and damage on an intestinal wall can be observed conveniently from the periphery of a recta in the surgical area; and after the inner bushing is inserted, water is introduced into the recta through the inner bushing and the pipe cavity opening on the inner bushing, a recta cavity is full, and recta damage can be judged by observing whether water leaks on the outer surface of the intestinal wall in the surgical area.

The present invention relates to medical devices. The prostate puncture positioner integrated with the flushing and disinfection three-way structure, including the puncture frame for fixing the puncture needle and the transrectal puncture probe, the head end of the puncture frame is flush with the head end of the transrectal puncture probe; The channel that guides the puncture needle to slide back and forth, and the channel is used to transport the disinfectant; the end of the channel is a three-way structure, and the three-way structure is integrated with the puncture frame; the rear end of the three-way structure is fixed with a sealed silicone seal Cover, the silicone sealing cover is used to pass through the puncture needle, and the puncture needle moves in the channel through the silicone sealing cover; the three-way structure is provided with an interface extending outward, and the interface is connected to the liquid outlet of a disinfectant injection system, and the disinfectant injection The system includes a storage chamber that stores a sanitizing solution. This patent realizes the sliding guide of the puncture needle with the traditional puncture frame, and at the same time, it can also realize the introduction of disinfectant, realize the precise disinfection of the rectal mucosa at the needle entry point and the complete aseptic state of the surrounding space when the puncture needle enters and exits the rectal mucosa.

The utility model relates to a curved-suction internal hemorrhoid cerclage device. It includes a curved tip inner tube, a curved sleeve to release the silicone ring, a barrel push sleeve and a negative pressure syringe. The arc-shaped suction head can easily absorb internal hemorrhoid tissue and rectal mucosa supplying blood vessels on the rectal wall with an L-shaped structure above the dentate line of the anal canal, and then perform cerclage. It is easy to operate with one hand and reduces the operation time. The negative pressure syringe has dual functions of generating negative pressure and serving as a handle of the cerclage, which simplifies the structure of the cerclage. The push sleeve track, track guide cylinder and wedge can ensure the smooth movement of the curved sleeve releasing the silicone ring along the inner tube of the curved tip, and it is not easy to fall off. The semi-circular wheel turns the curved surface between the cylindrical push sleeve and the arc-shaped sleeve that releases the silicone ring, thereby generating rolling contact and directly transmitting the power to the silicone ring to achieve light and smooth release of the silicone ring for cerclage Effect. The invention is reasonable in design, easy to use, and low in cost, so it is suitable for one-time use.

The invention relates to a pretreatment solution for exfoliated cells of rectal mucosa, which comprises the following components: methylisothiazolinone, shell iodine, trishydroxymethylaminomethane, disodium edetate, ethylphenyl polyethylene glycol Glycols, Sodium Chloride. The present invention also relates to a method for preparing the above pretreatment liquid. The present invention can provide a stable environment for cell samples, and has the effects of preventing coagulation and precipitation of tangible substances in samples, clearing mucus in samples, and reducing viscosity; Microorganisms, especially molds, in the pretreatment process of cell sample detection have the effect of disinfecting and inhibiting growth; The combined application of diol can maintain the integrity and good shape of exfoliated cells of rectal mucosa, thereby ensuring the accuracy of cell sample detection.

The invention provides a fluorouracil micro-emulsion as well as a rectal emulsion having bio-adhesion and temperature sensitivity and a preparation method of the emulsion. The micro-emulsion is prepared from the fluorouracil and a temperature-sensitive material and a bio-adhesion material are added into the micro-emulsion so that the rectal emulsion is prepared. The preparation is in the form of a solid under a room-temperature storage state, so that the stability of the preparation is enhanced; the preparation, which is refrigerated at 10 DEG C within a short time before being used, can be transformed into an emulsion which can flow freely, and the emulsion, after being used, can rapidly spread and cure in a rectum; the characteristics of a solid preparation and a liquid preparation are integrated; the emulsion is large in contact area between medicines and rectum surface, good in biocompatibility and excellent in strength and bio-adhesion force, and the emulsion can be firmly attached to rectal mucosa, so that an action time is prolonged; the medicine micro-emulsion carried in the preparation is high in transmucosal absorption efficiency; and the medicines are prevented from directly contacting mucosal tissues, so that irritation of the medicines to the rectal mucosa is relieved, the bioavailability and the treatment effect of the medicines are improved, and adverse reactions are reduced.