The invention discloses a query method for configurable information based on information system, comprising the following steps: receiving the user input checking configuration information, and generating the data configuration file, wherein the data configuration file comprises condition judging expression, query operational character, name of query field, type of query field, and external variable for receiving and storing query field value; analyzing the data configuration file, and generating the data queried query words; and dispatching the data source to query the words and return the query result. The invention improves the query efficiency and maintainability based on information system, and can support the query in file data manner, thereby reducing the technique difficulty of software information query; and the daily development can quickly respond to the customer demand, thereby improving the working efficiency, and greatly shortening time and reducing implementation cost.