The invention provides an insect-proof multi-layer eucalyptus wood board and a production method thereof. The production method of the multi-layer board comprises the steps of single plate thin platesorting, thin plate glue applying, cold pressing, hot pressing, standing curing, dust scraping, sanding, repair, trimming and plate pasting, and is characterized in that a layer of insect-proof curedfilm is sprayed at the peripheral surface, the upper surface and the lower surface of a slab before first hot pressing and final hot pressing to prevents glue from being dried too quickly during the hot pressing process and maintain stress inside the multi-layer board, the urea-formaldehyde glue can be fully reacted completely, the formed multi-layer board is not prone to mildewing, in the use process of a user, volatile formaldehyde is also reduced, and after hot pressing, the board is subjected to standing curing, sanding and plate pasting, so that the insect-proof multi-layer eucalyptus wood board product can be obtained by edge sawing and packaging.