The invention discloses a nursing lacrimal passage flushing fluid for infantile dacryocystitis and a preparation method of the flushing fluid. The flushing fluid is prepared from the following active pharmaceutical ingredients in parts by weight: sida acuta, semen lepidii, polygonum hydropiper, Chinese mosla herb, rhizoma bolbostematis, nephelium lappaceum, ganoderma, leaf and twig of nakedflower beautyberry, platycodon grandiflorum, all-grass of Chinese Ixeris, philippine violet herb, syneilesis aconitifolia, all-grass of delavay pararuellia, purslane seed, radix gentianae macrophyllae, herb of flannel mullein, lycopus lucidus, selfheal, sappan wood, lysimachia congestiflora Hemsl., rhizoma homalonemae and chestnut endocarp. The flushing fluid and the preparation method have the benefits that the efficacies of promoting evacuation of secretions in lacrimal sac, and thoroughly removing purulent or mucous secretions are promoted, the problem that the conventional lacrimal passage flushing fluid is irritant to eyes can be solved, and the advantages such as high efficiency, high effective rate, exact treating effect, short treating course, zero toxic or side effect, and low price are achieved.