91 results about "Halobenzene" patented technology

The present invention relates to additives for electrolytes of lithium ion secondary batteries that include one or more of the following: 1,3-propane sultone, succinic anhydride; ethenyl sulfonyl benzene, and halobenzene. It can also include biphenyl, cyclohexylbenzene; and vinylene carbonate. The weight of said 1,3-propane sultone is between 0.5 wt. % and 96.4 wt. %, said succinic anhydride is between 0.5 wt. % and 96.4 wt. %; said ethenyl sulfonyl benzene is between 0.5 wt. % and 95.2 wt. %; and said halobenzene is between 0.5 wt. % and 95.2 wt. % of the weight of the additive. Batteries with electrolytes containing said additives have improved over-charge characteristics and low temperature properties, and reduced gas generation during charging and discharging.

The invention discloses a halobenzene cyano pyrazol compound with the insecticidal action as well as a preparation method and application. The halobenzene cyano pyrazol compound is a compound shown in a structural general formula (1) or a pharmaceutically acceptable salt thereof. The compound has the advantages of little dosage, good insecticidal effect, simpleness in process method, low cost and wide market prospect.

The invention discloses a magnetic palladium composite catalyst, and a preparation method and a use thereof. The magnetic palladium composite catalyst adopts superparamagnetic Fe3O4@SiO2 microspheres as a carrier, the surface is covalently modified with supported amino Pd (II) particles, and the catalyst is obtained through the steps of sequentially preparing Fe3O4 nanoparticles, preparing core-shell structured magnetic nanometer microspheres Fe3O4@SiO2 and preparing a Fe3O4@SiO2 supported amino ligand. The magnetic amino palladium composite catalyst can be applied in a Suzuki reaction, can realize approaching equal conversion of halobenzene with an electron donating group or an electron withdrawing group, and has unobvious decreasing activity after the catalyst is continuously used 5 times due to no obvious decrease of the supported amount of an active ingredient.

The present invention relates to the preparation process and use of fluoro aromatic organic tetraacid dianhydride and its derivative. The present invention prepares fluoro aromatic organic tetrahydric dianhydride and its derivative through the Grignard reaction between metal trifluoroacetate and substituted halogeno benzene to produce alpha, alpha, alpha-trifluoromethyl phenyil ketone; the condensation reaction of the alpha, alpha, alpha-trifluoromethyl phenyil ketone and one-xylene under the action of strong acid to obtain fluoro aromatic tetramethyl compound; the high temperature nitric acid oxidation or KMnO4 oxidation of the fluoro aromatic tetramethyl compound to obtain fluoro aromatic organic tetracid; and the final dewatering. Fluoro aromatic organic tetrahydric dianhydride and its derivative may be prepared into fluoro aromatic polyimide with excellent comprehensive performance through condensation with aromatic organic diamine and subsequent imination.

A process for preparing substituted benzenethiol includes such steps as reaction between substituted halobenzene and thiohydrogenating reagent in non-protonic polar solvent while stirring, acidifying to pH=1-6, and distilling.

The invention relates to a method for synthesizing an amino biaromatic compound. The method comprises the following steps: reacting a nitroaromatic formic acid compound, an alkali and a solvent, removing water, adding substituted halobenzene, a catalyst and a ligand, and reacting; or reacting prepared dry nitroaromatic formate, substituted halobenzene, the catalyst, the ligand and the solvent; and extracting the obtained reaction product with the solvent, concentrating the obtained extract, and purifying the obtained concentrate to obtain the amino biaromatic compound. Compared with the prior art for synthesizing the amino biaromatic compound through two steps comprising coupling and reducing (such as hydrogenating), the method for synthesizing the amino biaromatic compound from cheap and easily available nitroaromatic formic acid and substituted halobenzene in the high-boiling point solvent under the action of the catalyst through a one-step reaction has the advantages of novel reaction, high safety, high yield, high efficiency, low cost and industrialization realization.

The invention relates to a method for synthesizing a nitrobiphenyl compound, and particularly relates to a method for synthesizing a nitrobiphenyl compound through C-H activation. The method is characterized in that chemical products, namely nitrobenzene and substituted halobenzene which are easy to obtain on the market, are used as raw materials, the synthesis of a key intermediate, namely 2-nitrobiphenyl of boscalid and analogues of the 2-nitrobiphenyl is realized by using a C-H activation means, and the purification of the intermediate is realized by using purification method-recrystallization. The method has atom economy and great potential and advantages in terms of industrialization. Compared with a conventional method, the method has the advantages that the two raw materials adopted by the method are easy to obtain and have the price advantages.

A process for the preparation of dihalodiphenylsulfones_such as 4,4′-dichlorodiphenyl sulfone or 4,4′-bis-(4-chlorophenylsulfonyl)biphenyl with high regioselectivity, at low temperature and in the absence of toxic reagents by reacting together at least one acid, at least one fluorinated anhydride and at least one halobenzene. The invented process is particularly suited for the manufacture of 4,4′-dichlorodiphenyl sulfone.

The invention provides a halobenzene functionalized and modified carbon nano tube and a preparation method thereof. The halobenzene functionalized and modified carbon nano tube is characterized in that after carboxy groups on the surface of a carbon nano tube are acylated, the halobenzene functionalized carbon nano tube is prepared through Friedel-crafts reaction by using a Lewis acid as a catalyst and using halobenzene as a modifying agent. The dosage of an oxidizing agent and the processing time are controlled during oxidization, so that the adoption amount of carboxy groups is controlled, and further the number of halobenzene ketone structures grafted by the carbon nano tube is controlled; the types of halobenzene are changed so as to obtain multiple kinds of halobenzene functionalized carbon nano tubes. The obtained modified carbon nano tubes have good solubleness in organic solvents, such as NMP and DMF, the carbon nano tubes can be well dispersed in a resin matrix by an in-situ polymerization and in-situ compounding method, and the obtained modified carbon nano tubes can be used for preparing high-performance nano composite materials, high-strength film materials and high-performance fibers, and can also be used for preparing superfine fibers and non-woven fabrics through electrostatic spinning. Therefore, the surface-functionalized modified carbon nano tube prepared by the method disclosed by the invention can be applied to the fields of plastic and fiber modification, and electrostatic spinning.

The invention discloses a new method of synthesizing a 1, 2, 3-triazol 1, 3-diazacyclo compound with pharmaceutical activity. The structure of the 1, 2, 3-triazol 1, 3-diazacyclo compound with pharmaceutical activity is shown in figure (1), wherein n is equal to 1, 2 or 3; z is an O atom, an S atom or NR'; R' is a hydrogen atom, methyl, nitryl, cyano, amido, C[1-8]alkyl, C[1-8]alkylamino, C[1-8]alkanoyl, aroyl, dense aroyl, aryl, dense aryl, naphthenic base, aralkyl, oxa-alkyl, oxa-acyl, thia-alkyl or thia- acyl; R is alkyl, aryl, substituted aryl or heterocyclic aryl; n is equal to 1, 2 or 3; Z is an O atom, an S atom or NH preferably; and R is methyl, phenyl, p-methylphenyl, p-chlorphenyl or p-methoxyphenyl preferably. The invention is characterized in that, substituted halobenzene, hydrazoates and heterocyclic ketene amines or derivatives thereof are used for preparing the 1, 2, 3-triazol 1, 3-diazacyclo compound which has pharmaceutical activity and has the structure shown in figure (1) at high yield by the one kettle way. The invention has the advantages of simple synthesizing technology, moderate conditions and high yield. The invention achieves the synthesis of heterocyclic compound libraries at high yield in a parallel mode by the one kettle way, and really achieves molecular multiformity. In addition, the invention has the characteristics of high yield, simple lines, moderate conditions and the like.

The invention provides an alkynyl carbon material, a preparation method thereof and a composite electrode, and the preparation method comprises the following steps: mixing calcium carbide, hexa-halobenzene and ball milling beads according to a mass ratio of the ball milling beads to the total mass of the calcium carbide and the hexa-halobenzene being (10-150): 1, and carrying out ball milling at 400-1000r/min for 24-48h to obtain mixed powder; and seiving the mixed powder, carrying out post-treatment, and obtaining the alkynyl carbon material. According to the preparation method of the alkynyl carbon material, the calcium carbide and the hexahalobenzene are induced to be subjected to a multi-phase chemical reaction through mechanical energy generated through mechanical ball milling and heat induction, the high-purity alkynyl carbon material is obtained through post-treatment, and the prepared alkynyl carbon material is high in purity and yield; and the alkynyl carbon material has high conductivity, nanoscale pores and interlayer spacing suitable for metal ion conduction, and is beneficial to lithium ion transmission and buffering of volume strain in the electrochemical reaction process.

The invention discloses a synthesis method of an acaricide cyflumetofen intermediate p-tert-butyl phenylacetonitrile, and belongs to the field of pesticide preparation. The synthesis method is characterized in that a reaction is performed on 4-tert-butyl halobenzene and cyanoacetate to obtain the p-tert-butyl phenylacetonitrile. A reaction process comprises the following steps: 1), under a protective gas condition, uniformly mixing the cyanoacetate, organic alkali and a solvent A, raising the temperature to 80-105 DEG C, controlling the pressure to be 3-5 atmospheric pressures, adding a solution of the tert-butyl halobenzene and a solvent B in three batches within 20-40 min, then controlling the reaction temperature to be 95-120 DEG C, controlling the reaction pressure to be 4-7 atmospheric pressures, carrying out a reaction for 1-3 hours, then adding deionized water, controlling the reaction temperature to be 130-150 DEG C, controlling the reaction pressure to be 6-9 atmospheric pressures, and continuing the reaction for 4-6 hours; 2), removing the solvents from a system by using a rotary evaporator, then transferring a remainder to water, adding a solvent C, stirring, layering, collecting an organic phase, drying by using a drying agent, then filtering, collecting a filtrate, distilling the filtrate under reduced pressure, and collecting a fraction with the temperature of 78-79 DEG C (0.1 torr) to obtain the p-tert-butyl phenylacetonitrile. According to the synthesis method, the steps are few, the yield is relatively high and the pollutant emission is less.

The invention discloses a preparation method of diphenyl disulfide compounds. The preparation method comprises the following steps: stirring an isopropyl magnesium halide Grignard reagent and a substituted halogen benzene compound in an organic solvent at -78 DEG C to -20 DEG C for 30-90 minutes to obtain a thoroughly halogen-magnesium exchanged substituted phenyl Grignard reagent; and adding dichlorodisulfide into the reaction system, slowly heating to room temperature after the reaction is finished, quenching the reaction by using a saturated ammonium chloride aqueous solution, extracting byusing ethyl acetate or diethyl ether, drying by using anhydrous magnesium sulfate, and concentrating the organic phase to obtain the diphenyl disulfide compounds. According to the method, the diphenyl disulfide compounds are prepared by taking the phenyl Grignard reagent as a raw material through a one-pot method, and has the following advantages: the synthetic route is short, the preparation process is simple, the cost is low, the operation is easy, the yield is excellent, and the industrial production is easy.

The invention relates to a polybenzimidazole compound with a pendant group containing fluorine, and a preparation method thereof. The compound is a nitrogen heterocycle polymer formed by using benzimidazole as a main chain structure and substituting H in an N-H group on an imidazole ring with a p-trifluoromethylphenyl group. The preparation method comprises the following steps: 1) dissolving polybenzimidazole in an organic solvent to obtain a PBI solution; and 2) respectively adding p-trifluoromethyl halobenzene, a catalyst and a dehydrogenating agent into the PBI solution, carrying out a condensation refluxing reaction at 110-130 DEG C for 12-24 h, and purifying and drying the obtained reaction product to obtain the polybenzimidazole compound with the pendant group containing fluorine. The polybenzimidazole compound with the pendant group containing fluorine has the advantages of good solubility, excellent chemical stability, high phosphoric acid doping rate, high high-temperature proton conductivity, and broad application prospects in the fields of proton exchange membrane fuel cells, fireproof fibers and high temperature-resistant adhesives.

The invention relates to a new process for the manufacture of fluoroaryl compounds and derivatives thereof, in particular of fluorobenzenes and derivatives thereof, and especially wherein said manufacture relates to an environmentally friendly production of the said compounds. Thus, the present invention overcomes the disadvantages of the prior art processes, and in a surprisingly simple and beneficial manner, and as compared to the prior art processes, in particular, the invention provides a more efficient and energy saving processes, and also provides a more environmentally friendly process, for the manufacture of nuclear fluorinated aromatics, and preferably of nuclear fluorinated fluorobenzenes. Accordingly, in one aspect of the invention, an industrially beneficial process for preparing fluorobenzenes from halobenzene precursors using HF to form hydrogen halide is provided by the present invention. A beneficial and surprisingly simple use of chlorobenzene as an industrially interesting starting material in the manufacture of fluorobenzene is provided.

The invention relates to a preparation method of a besilate compound. The preparation method of the besilate compound comprises the following steps of: enabling benzenesulfonic acid, halobenzene and sodium sulphide to react in the presence of a solvent and an oxidant to obtain a target product containing besilate. The preparation method of the besilate compound is simple to operate, cheap in materials, high in product yield, high in purity and good in industrial application prospect.

The invention relates to a method for preparing p-methoxycinnamic acid. The method comprises the following steps: a salt forming reaction: reacting acrylic acid with an alkaline inorganic salt to obtain acrylate; and a coupling reaction: reacting 4-methoxyhalobenzene and acrylate, and carrying out acidifying to obtain p-methoxycinnamic acid. According to the method, an organic phase reaction system is changed into a water phase reaction system; a brand-new, efficient and low-cost catalyst is adopted for catalysis; so high-quality p-methoxycinnamic acid is prepared at low cost, and the preparedp-methoxycinnamic acid has HPLC content of no less than 99.5%, single impurity content of no more than 0.2% and total impurity content of no more than 0.5%.

The invention provides a synthesis method of a 4-cyclopentyl biphenyl fluorinated compound. The method comprises the steps of taking p-chloro-halobenzene as a starting material and carrying out Grignard reaction to generate a Grignard reagent II of the p-chloro-halogenated benzene; enabling the generated Grignard reagent II of the p-chloro-halogenated benzene and cyclopentanone to be subjected toa coupling reaction to generate cyclopentanol chlorobenzene; carrying out a dehydration reaction to generate cyclopentene chlorobenzene; carrying out a one-pot reaction to generate 4-cyclopentenyl phenylboronic acid; enabling the generated 4-cyclopentenyl phenylboronic acid and fluorinated halogenated benzene to be subjected to a coupling reaction to generate a 4-cyclopentenyl biphenyl fluorinatedcompound; carrying out a hydrogenation reaction to obtain the 4-cyclopentyl biphenyl fluorinated compound. The synthesis method provided by the invention has the characteristics of being high in conversion rate, low in cost, safe and stable in process, short in reaction steps, environmentally friendly in process route, and less in pollutant emission.

The invention relates to the field of medicine synthesis, particular to a ketoprofen intermediate, a preparation method and applications thereof. The preparation method comprises the following steps:carrying out a Diels-Alder reaction on p-nitrohalobenzene or o-nitrohalobenzene or a mixture of p-nitrohalobenzene and o-nitrohalobenzene as a raw material and phenylacetonitrile to form an isoxazolecompound, and sequentially carrying out an oxidation reaction, a substitution reaction, a reduction reaction, deamination, ester group removal and an acidic hydrolysis reaction to prepare ketoprofen,wherein the reaction formula is defined in the specification, X2 or the group defined in the specification is located at the ortho-position or para-position of nitro or amino, R1 is -CONR4R5, -COX1, -COOR2 or -CN, R2, R3, R4, R5 and R6 are the same or different and are H or C1-C6 alkyl, and X1 and X2 are the same or different and are F, Cl, Br or I.

In a process of halogenation of benzene or benzene derivatives, di-substituted halobenzene derivatives having para-aromatic compounds or tri-substituted halobenzene derivatives having 1,2,4-substituted aromatic compounds are selectively produced. In halogenation of benzene or benzene derivatives, a fluorine-containing zeolite catalyst such as L-type zeolite, or a zeolite catalyst having the crystal size of at most 100 nm is used. The reaction is preferably effected in the presence of a solvent, and the solvent is preferably a halogenated compound.

The invention discloses a perfluoroalkyl styrene monomer and application thereof. The perfluoroalkyl styrene monomer is prepared by the following steps of using monohalogenated thiophenol and perfluoro-iodoalkane as the raw materials, so as to obtain an intermediate, namely perfluoroalkyl thiohalobenzene; further fluorinating, so as to obtain perfluoroalkyl tetrafluorothio methylene halobenzene; finally, reacting with vinyl magnesium bromide, so as to obtain perfluoroalkyl tetrafluorothio methylene styrene. The prepared tetrafluorothio methylene-containing perfluoroalkyl styrene has the advantages that the reaction property is realized, and the tetrafluorothio methylene-containing perfluoroalkyl styrene can be used for preparing fluorine-containing surface treatment materials and liquid-repelling surfaces; because the perfluoroalkyl is bonded with rigid benzene rings, the whole structure of the fluorine-compound has larger crystallizing property, and the excellent liquid-repelling property is obtained; the tetrafluorothio methylene is used as a bridge group, and is directly bonded with the benzene ring, and the good heat-resistant stability is provided by the electron stable reaction of large phi bond of the benzene ring corresponding to the sulfur tetrafluoride; the tetrafluorothio methylene-containing perfluoroalkyl styrene is easy to degrade under the radiation by ultraviolet light, and the obtained fluorine-containing material is environment-friendly.