830 results about "Benzenesulfinic acid" patented technology

The invention discloses a water-based environment-friendly finishing paint, which is prepared from the following compositions in part by weight: 20 to 70 parts of water borne acrylic resin solution of which the solid content is 30 to 80 percent and/or 20 to 70 parts of water borne epoxy resin solution of which the solid content is 30 to 80 percent, 4 to 10 parts of water borne amino resin solution of which the solid content is 60 to 98 percent; 1 to 5 parts of organic amine, 0.2 to 2 parts of wetting and leveling agent, 0.2 to 2 parts of thickener, 0.1 to 0.8 part of defoaming agent, 1 to 5 parts of adhesion promoter, 0.2 to 5 parts of catalyst, 10 to 30 parts of alcohol diluting solvent and/or 1 to 5 parts of nontoxic ether diluting solvent, and 20 to 50 parts of deionized water, wherein the catalyst is one or more of ammonias, alcohols and benzenesulfonic acids. The water-based environment-friendly finishing paint has the advantages of wide applicable range, high hardness, good flexibility, strong adhesion, good scratchproof performance, and environmental protection. Simultaneously, the invention also discloses a method for preparing the water-based environment-friendly finishing paint.

Provided herein are processes for the preparation of (S)-(2R,3R,11bR-3-isobuty-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-pyrido[2,1-a]isoquinolin-2-yl 2-amino-3-methylbutanoate di(4-methylbenzenesulfonate), or a solvate, hydrate, or polymorph thereof.

The invention relates to agomelatine benzenesulfonic acid compound of a formula I and a preparation method thereof; the agomelatine benzenesulfonic acid compound obtained by the invention is good in product stability, high in purity and is suitable for application demand when finished drug is prepared; preparation technology is also very simple; and a high-purity product can be obtained without special operation, wherein in the formula (I), R=CH3, H.

This invention relates to a method for preparing high-performance aminosulfonic acid-series water reducer with polyether-grafted comb-like molecular structure for cement. The high-performance aminosulfonic acid-series water reducer is prepared from: p-aminobenzenesulfonic acid 100 parts, NaOH 115-140 parts, phenol 10-100 parts, modified polyether 0-90 parts, formaldehyde 300-600 parts, and water 3000-10000 parts. The method comprises: dissolving p-aminobenzenesulfonic acid, NaOH, phenol and modified polyether in water at 5-50 deg.C, heating to 50-120 deg.C, dropping formaldehyde, and keeping the temperature for 1-9 h. The high-performance aminosulfonic acid-series water reducer can effectively inhibit the collapse loss of concrete. The high-performance aminosulfonic acid-series water reducer has high workability, and water cannot infiltrate into concrete containing it.

The invention discloses Rhodococcus ruber PTA-2, which is classified and named Rhodococcus ruber PTA-2, is preserved in the China General Microbiological Culture Collection Center on February 9, 2015, and has the preservation number of CGMCC NO.10538. According to the present invention, the Rhodococcus ruber PTA-2 can grow by adopting p-toluenesulfonic acid as the sole carbon source, wherein the degradation rate on the 500 mg/L p-toluenesulfonic acid is 96%; the immobilized pellets prepared from the Rhodococcus ruber PTA-2 provides the good p-toluenesulfonic acid degradation effect, wherein the degradation rate on the 500 mg/L p-toluenesulfonic acid is more than 90%; and the production cost is low, the use is convenient, and the Rhodococcus ruber PTA-2 is suitable for promotion and application in the p-toluenesulfonic acid-containing wastewater treatment.

The invention relates to the following general formula compound (I) and use of the general formula compound in preparing anti-inflammatory and anti-endotoxin medicines. In formula I, R is an acid solubilizing side chain of hydroxide radical in an arctigenin molecule, and can be an acid group or side chain imported through alkylation reaction or acylating reaction, such as sulphonic acid ester, sulfuric acid ester, organic phosphate, succinate, propionic ether, butyric ester, semi-succinate, semi-glutaric acid ester, semi-tartrate, semi-phthalic acid ester, m-benzene sulfonic acid ester and so on.

The invention discloses an oxa-phosphaphenanthrene fire retardant as well as a preparation method and application of the oxa-phosphaphenanthrene fire retardant. The fire retardant has a calyx[4]arene structure; p-tert-butyl calyx[4]arene and p-tosylate ethoxy p-benzaldehyde are prepared into an intermediate I in the presence of K2CO3 and acetonitrile, and the intermediate I reacts with DOPO to obtain a target compound; the compound is white in appearance, has the melting point of 198-200 DEG C and the purity of 98.5% and is good in thermal stability and high in flame retarding rate; the used raw materials are easily available, and a process is advanced and easy for industrialized production. The flame retardant not only can serve as a reactive flame retardant to be used in thermosetting resin such as epoxy resin and polyurethane but also can serve as an additive flame retardant to be used for engineering plastics with relatively high requirement on the heat resistance of the flame retardant.

The invention discloses an emulsifying agent having a stabilizing effect, which is one or a mixture of several of polyoxyethylene lauryl ether, polyoxyethylene nonyl phenyl ether, alkylaryl polyethenoxy ether, polyoxyethylated fatty acid, epoxy chloropropane, PO-EO block polyether, alkylphenol polyoxyethylene formaldehyde condensation product, calcium dodecyl benzene sulfonate, dodecyl benzenesulfonic acid, 2,6-di-tert-butyl-4-methyl phenol and tween-80. By adopting a method of combining a particular stabilizer with a reasonable formula, the problem of high decomposition rate after the clethodim is stored can be solved; and the characteristics are stable, the clethodim is free from having the layering and precipitation problems during the storage process, and the dilution stabilization of the emulsifible concentrates is qualified. The emulsifying agent is particularly suitable for preparing clethodim emulsifiable concentrates. By utilizing the clethodim emulsifiable concentrates which is prepared by the emulsifying agent having the stabilizing effect, the resource can be saved, so the clethodim can be maximally used; and the clethodim emulsifiable concentrates which is prepared by the emulsifying agent having the stabilizing effect have an excellent effect on preventing the gramineous weed, have no residual influence on the aftercrop crops and have good safety.

The invention relates to a novel synthesis route of glipizide, which is characterized by comprising the following steps of protecting 4-(2-amino ethyl)benzenesulfonic acid ammonia (II) by Boc anhydride to obtain a compound (III); reacting the compound (III) with cyclohexyl isocyanate to obtain a compound (IV); carrying out deprotection on the compound (IV) to obtain a compound (V); and reacting the compound (V) with 2-methyl-5-pyrazine carboxylic acid to obtain the glipizide (I) with the single impurity which is less than or equal to 0.5% and the high purity which is more than or equal to 99%. The process is simple, the yield is high, the purity is high and the single impurity is low; and the process is environment-friendly and industrial production is easy to realize.

The invention relates to isoalantolactone derivatives and salts thereof and provides an isoalantolactone derivative as shown in a formula (I). Salification acids are selected from inorganic acids or organic acids; the inorganic acids are selected from hydrofluoric acid, hydrochloric acid, hydrobromic acid, hydroiodic acid, sulfuric acid, nitric acid, phosphoric acid, carbonic acid, boric acid, seleninic acid, phosphomolybdic acid, phosphorous acid and sulphurous acid; the organic acids are selected from citric acid, maleic acid, D-malic acid, L-malic acid, DL-malic acid, L-lactic acid, D-lactic acid, DL-acid, oxalic acid, methylsulfonic acid, pentanoic acid, oleic acid, lauric acid, p-toluene sulfonic acid, 1-naphthalenesulfonic acid, 2-naphthalenesulfonic acid, phthalic acid, tartaric acid, malonic acid, succinic acid, fumaric acid, glycolic acid, mercaptan acid, glycine, sarcosine, sulfonic acid, nicotinic acid, methylpyridine acid, isonicotinic acid, benzoic acid or substituted benzoic acid.

The invention belongs to the technical field of microporous rubber and discloses a microporous rubber base plate and a preparation process thereof. The microporous rubber base plate has the major technical characteristic that the microporous rubber base plate body is prepared from the following components in parts by weight: 100 parts of ethylene-propylene-diene rubber, 6-18 parts of polyethylene glycol mixture, 60-100 parts of a filling material, 30-60 parts of alkane oil, 6-12 parts of a foaming agent, 2.5-5.5 parts of a vulcanizing agent and 2-5.5 parts of an accelerant. According to the microporous rubber base plate, an evenly diffused multi-phase structure is formed by mechanically blending low-Mooney EPDM and high-Mooney EPDM, and in combination with benzenesulfonic acid formed in the reaction process of neutralizing the foaming agent 4,4-oxodibenzenesulfonyl hydrazide by use of the polyethylene glycol mixture, the foaming ratio can be increased. In addition, accessories carbon black excellent in reinforcement property and porous diatomite filler excellent in aging property and light in weight are adopted, and consequently, the microporous rubber base plate has such properties as high strength, low rigidity and low temperature dependency.

The invention discloses a regeneration method of a Pd/C catalyst and an application of the regenerated Pd/C catalyst. The Pd/C catalyst is inactivated due to poisoning by sulfur-containing substances during the process of catalyzing the hydrogenation synthesis of m-aminobenzenesulfonic acid from m-nitrobenzenesulfonic acid; and the regeneration method comprises the steps of drying and oxidizing the inactivated Pd/C catalyst in an air atmosphere at the temperature of 50-140 DEG C to obtain the regenerated Pd/C catalyst. The Pd/C catalyst obtained by regeneration according to the regeneration method disclosed by the invention can be applied to the reaction of catalyzing the hydrogenation synthesis of the m-aminobenzenesulfonic acid from the m-nitrobenzenesulfonic acid. The method disclosed by the invention is environment-friendly and pollution-free, can effectively restore the activity of the Pd/C catalyst which is inactivated due to the positioning of the sulfur-containing substances during the process of catalyzing the hydrogenation synthesis of the m-aminobenzenesulfonic acid from the m-nitrobenzenesulfonic acid, can ensure that the catalyst can be mechanically used for more than 80 times in a circulating manner, and can keep the activity of the catalyst and the selectivity of the target product unchanged.

The invention discloses a method for preparing 9-oxo-10(9H)-acridineacetic acid, and belongs to the field of organic synthesis. The method comprises the following steps: (1) under the effects of a metal carbonate, a catalyst and a solvent, performing a condensation reaction on o-chlorobenzoic acid (a) and aniline (b) to prepare an intermediate c; (2) under the effects of toluene and p-toluenesulfonic acid, performing a cyclization reaction on the intermediate c by refluxing and dehydrating to prepare an intermediate d; (3) dissolving the intermediate d in dimethyl formamide , successively adding 60% NaH, KI and ethyl chloroacetate, reacting at room temperature to obtain a wet intermediate e; and (4) hydrolyzing the wet intermediate d with NaOH to obtain a crude product f, and refining the crude product f to obtain the 9-oxo-10(9H)-acridineacetic acid product. The method has the advantages of low cost consumption, small pollution during reaction, smooth and easy-controlling reaction and high product yield, and has better industrial application value.

The invention discloses a synthetic method for 2-methyl-3-trifluoromethyl phenylamine. The method comprises the following steps: 1) preparing 3-nitro-4-methyl benzenesulfonic acid; 2) preparing 3-nitro-4-methyl-5-bromobenzenesulfonic acid; 3) preparing 2-nitro-6-bromotoluene; 4) preparing 2-nitro-6-trichloromethyl toluene; 5) preparing 2-nitro-6-trifluoromethyl toluene; 6) preparing 2-methyl-3-trifluoromethyl phenylamine, that is, adding 5% palladium-charcoal and methanol in 2-nitro-6-trifluoromethyl toluene obtained in step 5), carrying out hydrogenation reduction at a temperature of 35 DEG C and removing a catalyst so as to obtain 2-methyl-3-trifluoromethyl phenylamine. According to the invention, p-toluenesulfonic acid is used as a starting material, and therefore, disadvantages of theprior art are overcome and yield of a target product is improved.

The invention provides a low-temperature fast-dry amino automobile chassis paint and a production method thereof, wherein, the paint consists of B-12 resin, medium pigment carbon black, compound ferrotitanium powder, ultra-fine mica powder, an auxiliary agent, sealed paratoluenesulfonic acid BYK-450 and BR-167 amino resin; B-12 resin is prepared by octadecenoic acid, benzoic acid, pentaerythritol, phthalic anhydride, dimethylol propionic acid, and trimethyl benzene. The automobile chassis paint adopts special B-12 resin synthetic route to lead the polymer chain to have more active functional groups simultaneously to be matched with the blocked paratoluenesulfonic acid, reduces the baking temperature of the existing amino paint from 130 DEG C to 90 DEG C and reduces the curing film-forming time from 1 hour to half an hour. As the paint film has high crosslinking density, compound ferrotitanium powder and squamous anti-rust pigment are matched for use, and the polyaniline is used for improving the anticorrosive potentials, thus leading the salt spray resistance of the paint to achieve 150 hours and improving the protection performance and the coating efficiency.

The invention relates to a kit and method for determining uric acid. The kit comprises a reagent set 1 and a reagent set 2, wherein the reagent set 1 comprises a chromogen; the reagent set 2 comprises 4-aminoantipyrine, peroxidase and uricase; and the chromogen is or comprises N-ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethoxyaniline. The kit and method can lower the interference caused by calcium phenolsulfonate and/or etamsylate in the sample in the uric acid detection process.

The invention relates to an aqueous macromolecular photoinitiator and a preparation method thereof. The general formula of the aqueous macromolecular photoinitiator is (i). The aqueous macromolecular photoinitiator prepared by the method has the photoinitiating efficiency equivalent to a corresponding micro-molecular photoinitiator and has better compatibility with an aqueous light-cured resin; carboxylate ions and sulfosalt ions exist in a molecular chain simultaneously, so the resin has better water solubility than an aqueous macromolecular photoinitiator only containing carboxylate ions; and in addition, the price of an introduced chain extender (4-aminobenzenesulfonic acid) used for sulfonic acid group is lower than that of a conventional aqueous functional monomer (dihydromethylpropionic acid), so that the cost of products is reduced and the industrial production is facilitated. At the same time, in the method, the chain is extended by using the functional monomer with photoinitiating function, so the content of photoinitiating radicals in the resin per gram is improved and the aqueous macromolecular photoinitiator has better photoinitiating efficiency than the aqueous macromolecular photoinitiator taking end radicals as the photoinitiating radicals.

The invention relates to methanol and isobutanol mixed ether amino resin and a preparation method thereof. The methanol and isobutanol mixed ether amino resin is prepared from the following components in percentage by weight: 15 to 30 percent of melamine, 20 to 30 percent of solid formaldehyde, 20 to 30 percent of methanol and 25 to 40 percent of isobutanol. The invention also provides the preparation method of the methanol and isobutanol mixed ether amino resin. The invention has the advantages that: the amino resin is prepared from the methanol and the isobutanol serving as modifiers, so that the cross-linking temperature can be greatly reduced, the requirements of energy saving and emission reduction are met, and the modified resin has high hardness, water resistance and chemical resistance; and p-toluenesulfonic acid and sodium hydroxide are taken as catalysts, so that reaction time is shortened, and the using amount of the catalysts is reduced.

The invention relates to the technical field of pesticide residue detection, and in particular relates to a hydroxyl-terminated hyperbranched polyurethane-ester polymer. The hydroxyl-terminated hyperbranched polyurethane-ester polymer is prepared by the following steps: implementing reaction between diisopropanol amine and methyl acrylate which are equal in molar mass to obtain an AB2 monomer; and carrying out reaction among AB2 monomer, p-toluenesulfonic acid and triethanolamine to obtain the hydroxyl-terminated hyperbranched polyurethane-ester polymer. The invention further relates to a hyperbranched polymer modified polydimethyl siloxane (PDMS) micro-fluidic chip and application of the hyperbranched polymer in the technical field of pesticide residue detection. The prepared PDMS micro-fluidic chip disclosed by the invention has permanent hydrophilcity, and is capable of effectively improving stability of a polymer coating, free from use of expensive instrument and reasonable in price; and the coated capillary has the characteristics of small size, simple operation, low sample dosage, high separation efficiency and high analysis speed, and is capable of separating and detecting organic pesticide residue very well.

The invention discloses a heteroatom-doped polymer nano microsphere with a core-shell structure and a preparation method thereof. The method overcomes lots of defects such as complexity and limitation of a template method, adopts mild reaction temperature (room temperature) and takes melamine, arylamine and aldehyde as raw materials, in the presence of 3,5-diaminobenzoic acid or 2,4-aminobenzene sulfonic acid, by utilizing the difference of the reaction rates of reactants in an acetone-water mixing system or a pure acetone system, Schiff base is generated by aldehyde and a general formula 3,5-diaminobenzoic acid or 2,4-aminobenzene sulfonic acid, the aromatic amine is added with the generated Schiff base to prepare a coated nano microsphere, and the nano microsphere with the core-shell structure is obtained by soaking or washing in different solvents. The process method is simple to operate, mild in condition and rapid in reaction; the nano microsphere product prepared by utilizing the method is controllable in size and morphology, uniform in particle size, uniform in dispersion, large in yield and capable of making heteroatom doping uniform and making material toughness enhanced. The method has a very good application prospect.