56 results about "Coated capsule" patented technology

The invention discloses a method for spraying a warning mark on the surface of an airplane heating part or an equipment component. The method comprises the following steps of: 1) treating the surface of an airplane on which the warning mark is to be sprayed so as to form a character surface on the surface of the airplane and form a plurality of colored recesses on the character surface; 2) spraying an encapsulated reversible temperature sensing and color change paint on the character surface so as to fill paint-coated capsule particles in the colored recesses on the character surface; 3) sintering the character surface; 4) coating a protective film layer on the sintered character surface; and 5) resintering the character surface and smoothing the coated character surface after the resintering. By the method, a sprayed warning character can directly reflect the surface temperature state of the airplane heating part or the equipment component, so that operation personnel are prevented from being scalded.

The invention discloses esomeprazole magnesium enteric capsules and a preparation method thereof. Esomeprazole magnesium is prepared into enteric coated pellets, and the enteric coated pellets are filled into gastric coated capsules. Each enteric coated pellet consists of an empty pellet core, a medicine carrying layer, two isolating layers, an enteric coated layer and a film coating layer. In order to guarantee stability of medicines, alkaline materials are added in the empty pellet cores; alkali stabilizers and antioxidant are added in the medicine carrying layer; and a high-alkalinity modifier and a low-alkalinity modifier are respectively added in the two isolating layers of each enteric coated pellet. In order to guarantee a dissolution effect, surfactant is added in the enteric coated layers; and stability of products is improved owing to the film coating layers wrapping the outer layers of the enteric coated pellets. Owing to optimized formulation and technology of the pellets, smoothness of a technology is improved, work efficiency is also improved, coating time is shortened, consumption of labor and materials is reduced, and production cost is reduced.

Described is a spherical coated capsule comprising (a) a coating-free capsule having (i) a liquid or viscous core and (ii) a seamless solid shell surrounding this core, and (b) a seamless, solid coating surrounding said coating-free capsule, wherein - the diameter of the coated capsule is in the range of 5 - 9 mm, - the solid coating comprises at least one sugar or sugar-alcohol in an amount from about 30 - 90% (m/m), based on the total mass of the coated capsule, - the diameter of the coating-free capsule is in the range of 3 - 7 mm, the thickness of the shell of said coating-free capsule is in the range of 20 - 200 m, - the ratio of shell thickness to diameter of said coating-free capsule is in the range of 0.004 - 0.04 , - the shell of said coating-free capsule contains 70 - 90 % (m/m) gelatine or alginate and 10 - 30 % (m/m) plasticiser, based on the solids content of said shell, and - the core has a flavouring content in the range of 1 - 100 % (m/m), based on the total mass of the core. Further described is a method for preparing such capsule.

Pharmaceutical formulations, preferably in the form of softgel capsules or hard-shell capsules, exhibit extended release through the use of a coating comprising a water-insoluble polymer and a pH-independent pore former. Extended release from softgel capsules and hard-shell capsules can be achieved without the use of lipid-based semi-solid or solid materials.

The invention relates to a lansoprazole compound and a pharmaceutical composition thereof. The lansoprazole compound is a crystal. The characteristic peaks measured by X-ray powder diffraction are shown as 3.6, 4.8, 10.9, 14.0, 15.4, 16.9, 22.6, 24.7, 28.5, 32.1, 35.2, 36.7 and 39.3 at 2theta+/-0.2 degrees. The medical composition preparation comprises the lansoprazole compound. The preparation is in form of freeze-dried powder injections, troches, capsules, enteric-coated tablets or enteric-coated capsules. The lansoprazole compound prepared by the invention has better solubleness and stability. The lansoprazole pharmaceutical composition prepared by using the lansoprazole compound provided by the invention as the effective component is good in stability.

A method of producing a dried formulation for an active substance such as a drug compound is described. The method involves dispersing a discontinuous phase (e.g. an oil-based or lipidic medium) comprising the active substance into a continuous phase (e.g. water) so as to form a two-phase liquid system comprising droplets of said discontinuous phase, allowing nanoparticles to congregate at the phase interface at the surface of the droplets such that at least one layer of nanoparticles coat the droplets and thereby provide sufficient structural integrity to the droplets to enable the subsequent removal of the continuous phase, and thereafter removing the continuous phase from the nanoparticle-coated droplets to produce a dried formulation.

The invention provides a traditional Chinese medicine capsule capable of clearing heat and removing toxicity. The traditional Chinese medicine capsule comprises following raw materials, by weight: 10 to 15 portions of lonicera japonica, 5 to 10 portions of folium isatidis, 10 to 20 portions of fructus forsythia, 10 to 20 portions of coptis chinensis, 5 to 10 portions of radix scutellariae, 10 to 30 portions of radix isatidis, 10 to 20 portions of burdock seed, 10 to 20 portions of rhizoma phragmitis, 5 to 10 portions of bamboo leaf, 10 to 20 portions of rhizoma smilacis glabrae and 5 to 10 portions of gardenia jasminoides ellis. The traditional Chinese medicine capsule is prepared by following steps: taking the raw materials at the weight ratio, grinding the raw material into powder and adding the mixture into a sugar-coated capsule. The traditional Chinese medicine capsule is taken with warm water. Advantages of the traditional Chinese medicine capsule are that: curative effect is substantial; effectiveness is fast; the traditional Chinese medicine capsule is capable of clearing heat and removing toxicity, and possesses no side effects; and cost is low.

The invention relates to a pantoprazole sodium compound which is a crystal and is determined by X-ray powder diffraction. Characteristic peaks of the pantoprazole sodium compound are shown to be 7.2, 9.1, 11.0, 11.8, 14.7, 16.1, 18.4, 21.0, 23.5 and 25.2 at 2thet in a map. The invention also relates to a preparation method and a pharmaceutical composition of the pantoprazole sodium compound. The pharmaceutical composition comprises injection powder injection, enteric-coated tablet or enteric-coated capsule. Compared with the prior, the prepared pantoprazole sodium compound and the pharmaceutical composition thereof have obvious advantage in terms of quality stability.

The present invention relates to coated capsules with increased capsule shell pliability and resilience and methods of making the coated capsules. The present invention relates to methods of making coated capsules, the methods comprising applying a coating solution comprising sodium carboxymethylcellulose or sodium alginate to the exterior of a capsule to form a coating and drying the coating to produce a coated capsule.

The invention provides an oxiracetam enteric-coated capsule. Oxiracetam in special crystallization form is used as an active component. A composite carrier containing polyoxyethylene PEO and hydroxypropyl methyl cellulose ( or polyvinylpyrrolidone) in the mass ratio of the polyoxyethylene PEO to the hydroxypropyl methyl cellulose being (1-3) to 1, is carefully selected, and the prepared oxiracetamenteric-coated preparation can reduce the dissolution rate of the active component in the stomach, and also has favorable slow control slow release properties and storage stability. The prepared oxiracetam enteric-coated granules are subjected to long-term stability test under the condition that the temperature is 25 DEG C+/-2 DEG C, and the relative humidity is 60%+/-10%, and after long-term experiment for 24 months, sample properties, content and related substances all conform to specification. The oxiracetam enteric-coated capsule is good in stability, and long in quality guarantee period.The preparation method is simple, and suitable for industrial production.

The invention discloses a phosphorus-free, fluorescent agent-free and preservative-free super-concentrated capsule granule laundry detergent, a preparation method and a use method thereof, wherein the phosphorus-free, fluorescent agent-free and preservative-free super-concentrated capsule granule laundry detergent comprises 40-50% of fatty acid methyl ester sulfonate MES, 30-40% of natural soap powder, 1-5% of sodium olefin sulfonate AOS, 5-10% of sodium gluconate, 1-5% of isomeric alkanol ether EH-7, 1-3% of microcapsule essence, 1-2% of a suspending agent, 8-15% of coating powder, and 1-3% of granule compound enzyme. According to the present invention, the coating capsule concentration granulation process is used, the phosphorus-free, fluorescent agent-free and preservative-free super-concentrated capsule granule laundry detergent does not contain phosphorus, the fluorescent agent and the preservative, and the natural interface surfactant and the microcapsule essence are selected; and during the use, the skin irritation and the environmental pollution of the fluorescent agent, the preservative and the interface surfactant can be effectively reduced, and the aroma can emit during the washing process and can stay on clothing for a long time.

The present invention is method of producing penetrating pump capsule as one new dosage form from common capsule. This kind of new dosage has the features of both common gastric coated capsule and enteric coated capsule and its medicine is controlled to release safely and in long action and absorbed in both stomach and intestines in certain propertion. With material similar those in common capsule, the medicine and active penetrating supplementary material are filled into capsule, and the capsule coating is coated with coating liquid in certain thickness before one or several holes are drilled.

The invention discloses an injection molding method and device for preparing a large-size high-temperature-resistant and high-pressure-resistant expansion coated capsule from ultrahigh-viscosity silicone rubber. Part of the composite material has a large-size complex internal structure, so that the composite material has difficulties in preparing and demoulding processes, and the problems of uneven mixing, poor storage and the like of the double-component high-viscosity rubber in a rubber injection process are extremely prone to occurring during injection molding. The invention provides the injection molding method and device for preparing the large-size high-temperature-resistant and high-pressure-resistant expansion coated capsule from the ultrahigh-viscosity silicone rubber in order tosolve the problems, and relates to a two-component resin tank, an extrusion device, a vacuum device, a mixer and a mold. A material A and a material B are independently stored in the material storagebox, a vacuum device is connected into the material storage box, the material A and the material B in a ratio of x:y can be extruded into the mixer through an extrusion device during use, the mixed material passes through the mutichannel mixer during injection into the mold, rotating blades are installed in the mixer, and finally the mixed material is injected into the mold. According to the invention, rubber products with certain thickness, temperature resistance, long size and anisotropy can be produced.