Erythromycin enteric-coated capsule and preparation thereof

Abstract

The invention provides an erythromycin enteric-coated capsule and the preparation method. The invention is characterized in that: the component ratio of the enteric-coated liquid of the enteric-pellets capsules contained in the enteric-coated capsules counted by weight percentage is that: polyacrylic resin: II: 1, diethyl phthalate: 0.07 to 0.1, Tween-80:0.08 to 0.12, castor oil: 0.08 to 0.12, ethanol whose concentration is bigger than or equal to 95%: 12 to 14; all are counted as weight percentage. The invention conquers defects in the prior art, elevates the product quality, keeps the releasing degree of the product stable and guarantees the quality as well as healing effect of the product during the period of validity, and also the preparation is simple and convenient, the work efficiency is high and the quality of the products is quite well.

Description

technical field

[0001] The invention relates to an erythromycin enteric-coated capsule and a preparation method thereof. Background technique

[0002] Erythromycin enteric-coated capsules belong to antibiotic drugs, and the main indications are 1. As an alternative drug for penicillin-allergic patients to treat hemolytic streptococcus, Streptococcus pneumoniae and other infections; 2. Legionnaires’ disease; 3. Mycoplasma pneumoniae pneumonia; 4. Pneumonia Chlamydia pneumonia; 5. Other genitourinary infection caused by Chlamydia and Mycoplasma, Chlamydia trachomatis conjunctivitis, gonococcal infection, oral infection caused by anaerobic bacteria, Campylobacter jejuni enteritis, whooping cough, etc. Because erythromycin is very irritating to the stomach, the content of the existing erythromycin capsules adopts enteric-coated pellets, that is, enteric-coated pellets are coated on the pellets to prevent the release of erythromycin in the stomach, so that it is only The therape...

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