14 results about "Dimethyl phosphonate" patented technology

This invention provides a method for preparing high-purity olaparib, belonging to the field of pharmaceutical synthesis technology. The method uses dimethyl (3-oxo-1,3-dihydroisobenzofuran-1-yl)phosphate as the starting material, reacting it with compound 2 via a Wittig reaction to generate compound 3. Compound 3 reacts with hydrazine hydrate to generate compound 4. Compound 4 is hydrolyzed and acidified to give compound 5. Compound 5 reacts with thionyl chloride to give compound 6. Compound 6 is then condensed with compounds 7 and 9 to obtain olaparib. This invention uses readily available raw materials, is simple to operate and process, has mild reaction conditions, achieves a total yield of up to 90%, a purity >99%, is environmentally friendly, and is suitable for industrial production.

The application discloses modified cotton fabric and a preparation method and application thereof, and relates to the field of textile fabrics.In the preparation of the modified cotton fabric, chitosan is pretreated by 2-bromoisobutyryl bromide, then acrylic acid and methyl acrylate are grafted and polymerized by an atom transfer radical polymerization method to obtain pre-modified chitosan, then the pre-modified chitosan is sequentially reacted with oxalyl chloride and 4-hydroxybenzotriazole to prepare modified chitosan; cotton fabric is ultrasonically pretreated by a sodium dodecyl sulfate solution, then sequentially reacts with 6-chlorohexanoyl chloride and N,N-dimethylallylamine to prepare pre-modified cotton fabric, and finally, the pre-modified cotton fabric is reacted with a modified liquid prepared from modified chitosan, dimethyl phosphite and 1,4-butanediol to prepare the modified cotton fabric.The modified cotton fabric prepared by the application has excellent ultraviolet resistance, antibacterial property, wrinkle resistance and flame retardance.

The invention relates to the technical field of chemical fertilizer anti-caking agents, and discloses an attapulgite-based chemical fertilizer anti-caking agent and a preparation method thereof.The preparation method specifically comprises the steps that urea, dimethyl phosphite, a formaldehyde aqueous solution, itaconic acid and tripotassium citrate serve as raw materials, and a Mannich reaction, a dehydration reaction and an esterification reaction are conducted in sequence to prepare an alkenyl nitrogen phosphorus potassium compound nutrition component; the preparation method comprises the following steps: carrying out ring-opening reaction on hydroxyl groups on the surface of attapulgite and epoxy groups in allyl glycidyl ether to prepare alkenylated attapulgite; the preparation method comprises the following steps: by taking alkenylated attapulgite and an alkenylated nitrogen-phosphorus-potassium compound nutrient component as main raw materials and N, N-methylenebisacrylamide as a cross-linking agent, preparing functionalized attapulgite by adopting a solution polymerization method under the action of an initiator; functionalized attapulgite and fatty alcohol-polyoxyethylene ether are used as raw materials and are mixed, ground and sieved to prepare the chemical fertilizer anti-caking agent. The fertilizer prepared by adding the chemical fertilizer anti-caking agent prepared by the invention shows excellent anti-caking performance.

The invention discloses a foam foaming material special for an automobile headrest and a preparation method of the foam foaming material, and relates to the technical field of automobile part manufacturing, the foam foaming material comprises a component A and a component B. The component B comprises three formulas B1, B2 and B3 of different catalytic systems; the component A is polyphenyl polymethylene polyisocyanate, the functionality of the component A is 2.6-2.8, and the mass content of NCO is 30%-32%; the basic formula of the component B comprises the following components in parts by weight: 40-60 parts of polyether polyol with the functionality of 3 and the hydroxyl value of 450-500 mg KOH / g; the solid content of the polymer polyether polyol is 40-45%: 20-40 parts; 1 to 3 parts of a crosslinking agent diethanol amine; 1.5 to 3.5 parts of foaming agent water; 1-2 parts of a silicone oil surfactant; 5 to 15 parts of a flame retardant dimethyl methylphosphate; 0.5 to 1.5 parts of an anti-aging agent; by adopting the formula of the component B with three different catalytic systems and combining with a partitioned material injection technology, a gradient hardness structure of a main supporting area, a comfortable fitting area and an edge transition area can be accurately formed in the automobile headrest foam.

The application discloses a preparation method of an intrinsically flame-retardant high-elasticity styrene-acrylic emulsion, which comprises the following steps: preparing a phosphorus-nitrogen integrated functional compound by using glycine, polyformaldehyde and dimethyl phosphite as raw materials; performing acyl chloride modification on the phosphorus-nitrogen integrated functional compound by using sulfoxide chloride; preparing a high-flexibility flame-retardant monomer by reacting the acyl chloride modified phosphorus-nitrogen integrated functional compound with a phenolic hydroxyl cashew phenol; and finally preparing the flame-retardant high-elasticity styrene-acrylic emulsion by reacting the high-flexibility flame-retardant monomer, styrene, butyl acrylate and acrylic acid in a cationic etherified starch aqueous solution. The emulsion has the multiple advantages of flame retardation, high elasticity, soap-free, water resistance and the like, is green and environment-friendly, low in cost, and has a wide application value.

The present application relates to a method for preparing glyphosate spherical crystal, and belongs to the technical field of pesticide production. The steps include: taking the glyphosate synthesis solution obtained by the glycine-phosphite dimethyl ester method as a raw material, adding concentrated hydrochloric acid with a molar ratio of 2-5 to glycine and a concentration of 30% or more to the glyphosate synthesis solution for acidolysis; heating the acidolysis solution to 95-125 DEG C and keeping it for 0.5-2 hours for dealcoholization; after dealcoholization, the temperature of the system is reduced to 50-80 DEG C within 1-2 hours, and an alkali solution with a mass concentration of 35-42% is added while reducing the temperature, the pH of the system is controlled to be 0.5-3.5, and the stirring speed is kept at 180-250 rpm; then the temperature of the material is reduced to 20-40 DEG C within 1-2 hours, and the glyphosate spherical crystal product is obtained after filtration and washing. The spherical glyphosate obtained by the present application has good flowability, is not easy to agglomerate, has a larger tap density, and is easy to store and transport.

The utility model discloses a low-energy-consumption system for synthesizing dimethyl phosphite, and belongs to the technical field of dimethyl phosphite synthesis. The low-energy-consumption system comprises a micro-channel reactor, a gas-liquid separation device, a normal-pressure tail gas washing tower and a vacuum deacidification device, the micro-channel reactor is connected with a methanol feeding pipe, and the micro-channel reactor is connected with a phosphorus trichloride feeding pipe; the micro-channel reactor is connected with the gas-liquid separation device, the gas-liquid separation device is connected with the normal-pressure tail gas washing tower, and the gas-liquid separation device is connected with the vacuum deacidification device; the vacuum deacidification device is connected with the vacuum tail gas washing tower; the vacuum deacidification device is connected with the dimethyl phosphite rectification system; a continuous path for synthesizing dimethyl phosphite is formed among the micro-channel reactor, the gas-liquid separation device, the vacuum deacidification device and the dimethyl phosphite rectification system. The low-energy-consumption system not only reduces the energy consumption, but also ensures the high efficiency and continuity of the related synthesis process, and can be well matched with the dimethyl phosphite synthesis process to meet the actual requirements.

The utility model discloses a negative-pressure treatment device for tail gas generated in dimethyl phosphite production. The negative-pressure treatment device comprises a vacuum part, a condensation part and an absorption treatment part, the vacuum part comprises a buffer tank A, a Roots vacuum pump unit and a buffer tank B, the buffer tank A is provided with a tail gas inlet A, a tail gas outlet A and a methanol collecting tank A, the tail gas outlet A is connected with the Roots vacuum pump unit through a gas inlet pipeline, the Roots vacuum pump unit is connected with the buffer tank B through a gas outlet pipeline, and the top of the buffer tank B is provided with a tail gas outlet B; a methanol collecting tank B is arranged at the bottom of the buffer tank B; the condensing part comprises a condenser and a methanol collecting tank C, the tail gas outlet B is connected with the condenser, and the lower end of the condenser is connected with the methanol collecting tank C; the absorption treatment part comprises a multi-stage water absorption tower and an alkali absorption tower, the condenser is connected with the multi-stage water absorption tower, the multi-stage water absorption tower is connected with the alkali absorption tower, and a tail gas output pipeline is arranged at the top of the alkali absorption tower; the device disclosed by the utility model has the advantages of low production cost, high recycling rate and good chloromethane product quality.

This invention discloses a preparation process for a weather-resistant polyurethane coating material, relating to the field of coating material technology. In preparing the weather-resistant polyurethane coating material, sericite is pretreated and then reacted with cinnamaldehyde to obtain modified sericite; a high-efficiency flame retardant is prepared by reacting 3,5-diamino-1,2,4-triazole sequentially with p-methoxybenzaldehyde and dimethyl phosphite using a one-pot method; polytetrahydrofuran diol, benzoyl diols, and 4,4'-dicyclohexylmethane diisocyanate are polymerized to obtain polyurethane; the polyurethane, high-efficiency flame retardant, and modified sericite are mixed using DMF as a solvent to formulate a polyurethane coating, which is then dried to obtain the polyurethane coating material. The polyurethane coating material prepared by the process provided by this invention possesses the advantages of weather resistance, flame retardancy, and antibacterial properties.

Provided is a method for preparing a flame retardant cellulose ester film, and the method includes: obtaining a homogeneous cellulose solution by adding a cellulose to an ionic liquid cosolvent system; obtaining a cellulose phosphite ester solution by adding dimethyl phosphite and a catalyst to the homogeneous cellulose solution for performing a transesterification; obtaining cellulose phosphite ester powder by regeneration solvent precipitation, washing, centrifugation, and drying of the cellulose phosphite ester solution; and obtaining the flame retardant cellulose ester film by evaporating solvent after dissolving the cellulose phosphite ester powder in dimethyl sulfoxide.

The invention relates to the technical field of chemical engineering, and particularly discloses a method for improving glyphosate synthesis yield, which comprises the following steps: S1, carrying out depolymerization reaction by taking paraformaldehyde as a raw material, methanol as a solvent and anhydrous triethylamine as a catalyst to prepare a formaldehyde monomer and obtain a depolymerization solution, then adding glycine to carry out addition reaction to prepare N-hydroxymethyl glycine, and carrying out reduced pressure distillation to obtain N-hydroxymethyl glycine; an addition liquid is obtained; s2, carrying out reduced pressure distillation treatment on the addition liquid until the volume of the addition liquid is reduced by 25-45%; and S3, detecting the contents of methanol and triethylamine in the liquid obtained in S2, supplementing anhydrous triethylamine and absolute methanol, dropwise adding dimethyl phosphite, carrying out a reaction, and finally carrying out acidification, crystallization and separation post-treatment to obtain a glyphosate product. According to the method, reduced pressure distillation is introduced after depolymerization and addition, water is efficiently removed by utilizing the multi-element azeotropic characteristic of methanol-water-triethylamine, and meanwhile, a drying reagent is accurately supplemented, so that dual stabilization of the water content of a system and the concentration of a catalyst is realized, and the hydrolysis loss of dimethyl phosphite is reduced.

The invention discloses a resourceful treatment method and a control system for wastewater generated in production of dimethyl phosphite, and relates to the technical field of resourceful utilization of wastewater generated in production of dimethyl phosphite. The method at least comprises one of the following steps: a, carrying out oil-water separation treatment on vacuum pump wastewater generated in a deacidification section in dimethyl phosphite production, and after an oil phase is separated out, treating a gas phase generated in dimethyl phosphite production by using the remaining water phase; and b, using the vacuum pump wastewater generated in a rectification section in dimethyl phosphite production to treat a gas phase generated in dimethyl phosphite production, and meanwhile, providing a system suitable for the method, so that the wastewater treatment cost is remarkably reduced.

The invention relates to a method for feeding dimethyl phosphite by adopting a microchannel reactor, a process system comprises a microchannel reaction unit, a primary deacidification treatment unit and a post-system treatment unit, a methanol material inlet and a phosphorus trichloride material inlet are respectively arranged on two branch channels at one end of a microchannel, the other end of the microchannel is a product outlet, and the other end of the microchannel is a product outlet. The product outlet is connected with a top feed port of a first-stage deacidification kettle of the first-stage deacidification treatment unit through a pipeline, a bottom discharge port of the first-stage deacidification kettle is connected with a rear system, a heat-conducting medium cavity is formed among an upper heat-insulating plate, a lower heat-insulating plate and a shell, the upper heat-insulating plate is provided with a heat-conducting medium inlet, and the lower heat-insulating plate is provided with a heat-conducting medium outlet; the technological process comprises the following steps: S1, conveying methanol and phosphorus trichloride raw materials; s2, carrying out a reaction between the materials; s3, carrying out deacidification treatment; s4, purifying the dimethyl phosphite; through the advantages of the micro-channel reactor, the reaction efficiency and the product purity are improved, side reactions are reduced, and the method has a good industrial application prospect.

The application discloses an electrolytic zinc-manganese aqueous battery, which comprises a positive electrode, a zinc metal negative electrode and an electrolyte; the electrolyte comprises a manganese salt, a zinc salt, water, an acid and an electrolyte additive; and the electrolyte additive is hydroxymethyl (sub) dimethyl phosphate. The hydroxyl and phosphate groups in the hydroxymethyl (sub) dimethyl phosphate synergistically induce electrolysis effect. The phosphorus-oxygen double bond in the phosphate group can open the metal manganese and zinc cations in the complex electrolyte, and the metal manganese and zinc cations can quickly migrate to the electrode-electrolyte interface for electrochemical oxidation-reduction reaction under the guidance of the hydroxyl, so that the deposition-dissolution chemistry of the manganese dioxide and zinc cations is improved, and the catalytic electrolysis reaction kinetics is improved.