4 results about "Methylphosphate" patented technology

Compounds of the Formula (I), pharmaceutical compositions comprising compounds of the Formula (I), and their use for treating or preventing cancer: (I)

The invention provides a method for preparing 5-hydroxymethylfurfural or a derivative thereof and 2, 5-furandicarboxylic acid, which comprises the following steps of: preparing 5-hydroxymethylfurfural or a derivative thereof and 2, 5-furandicarboxylic acid by using streptomyces S with the preservation number of NCIMB 43995 and an MfnB gene which is separated from the strain and is used for coding (5-formyl furan-3-yl) methyl phosphate synthase (EC 4.2. 3.153); at least one carbonaceous raw material added with glucose is biocatalytically converted into 5-hydroxymethylfurfural or a derivative thereof and 2, 5-furandicarboxylic acid through intermediates such as glyceraldehyde-3-phosphoric acid and 4-hydroxymethyl-2-furan formaldehyde phosphate.

The invention discloses a preparation method of 3-(difluoromethyl)-1-methyl-pyrazole-4-carboxylic ester and difluoropyrazole acid, which comprises the following steps: reacting 3-(difluoromethyl)-1H-pyrazole-4-carboxylic ester with a first methylation reagent in a methyl phosphate solvent to obtain dimethyl pyrazolium cation salt, and reacting the dimethyl pyrazolium cation salt with a second methylation reagent to obtain the 3-(difluoromethyl)-1-methyl-pyrazole-4-carboxylic ester. And then under the action of a second methylation reagent and a nitrogen-containing reagent, 3-(difluoromethyl)-1-methyl-pyrazole-4-formate is obtained. The preparation method provided by the invention has the advantages of low isomer content, no need of high-temperature and high-vacuum distillation for isomer separation, and simple post-treatment, the methylation reagent and the methyl phosphate solvent can be recycled and repeatedly used for synthesis of the target product difluopyrazole acid, the raw material cost is reduced, and the preparation method has the advantage of environmental protection, and is suitable for industrial production.

The invention provides a sodium ion battery electrolyte and a sodium ion battery. The sodium-ion battery electrolyte comprises a sodium salt, an organic solvent and an additive, wherein the additives comprise a flame-retardant additive and a high-temperature additive, and the mass ratio of the flame-retardant additive to the high-temperature additive is (0.1-0.5): (0.5-1.0); the flame-retardant additive comprises at least one of trimethyl phosphate, triethyl phosphate and dimethyl methylphosphate, and the high-temperature additive comprises at least one of 1, 3-propane sultone and ethylene sulfate. By applying the technical scheme of the invention, through the mutual synergistic effect of the flame-retardant additive and the high-temperature additive in a specific mass ratio, the thermal stability of the electrolyte is improved, and the stability of an electrode interface is enhanced, so that the cycle performance and safety of the sodium-ion battery in a high-temperature environment are improved.