Monascus purpureus induced strain and water-soluble functional monascus as well as preparation method and application of water-soluble functional monascus

Abstract

The invention discloses a monascus purpureus induced strain and water-soluble functional monascus as well as a preparation method and application of water-soluble functional monascus. The monascus purpureus induced strain is preserved at China Center for Type Culture Collection on September 3, 2018, and the preservation number is CCTCC NO: M2018586. The monascus purpureus induced strain can be used for producing high-open-loop functional monascus and hardly produces citrinin. In addition, the monascus purpureus induced strain is arranged in a special fermentation culture medium to be further fermented in a liquid state to efficiently synthesize monacolin K with a high-open-loop structure, then the nonacolin K is processed by virtue of an after-treatment process to obtain the water-solublefunctional monascus, and the water-soluble functional monascus adopting a high-open-loop acidic structure as a main body has the characteristics of good water solubility, excellent flavor, no citrininor extremely low content of the citrinin. Moreover, a fermentation raw material is a non-glycerinum raw material, so that the potential safety hazard of glycerinum residue can be avoided. The preparation method provided by the invention has the advantages of being simple in process, easy in mass production, pollution-free and environmentally friendly; and the prepared product meets the safety quality requirement of food, healthcare products and drugs.

Description

technical field [0001] The invention relates to the field of biotechnology, more specifically, to a mutagenic strain of Monascus purple, a water-soluble functional red yeast rice, a preparation method and application thereof. Background technique [0002] Red yeast rice has the effects of invigorating the spleen and stomach, promoting blood circulation, removing blood stasis and relieving pain. It has a long history of edible and medicinal use in my country. In 1979, Endo et al. found that the Monacolin series of substances contained in the red yeast rice of a special Monascus can inhibit the HMG-CoA reductase (HMG-CoA reductase) in the biosynthesis of cholesterol in the human body. The role of this kind of red yeast rice is called lipid-lowering red yeast rice, also known as functional red yeast rice. [0003] With the gradual improvement of people's living standards and the increasingly obvious problem of aging population, the incidence of hyperlipidemia is increasing yea...

AI Technical Summary

Problems solved by technology

Due to the limitation of solid-state fermentation conditions, it is difficult to regulate the secretion of extracellular and extracellular metabolites in the solid-state fermentation of the triangular flask. The production of red yeast rice with high ring-opening function has not been reported, and the solid-state fermentation product has a severe bitter taste and is difficult to dissolve in water.

The liquid fermentation of glycerin, because glycerin is a chemical raw material, GB2760-2014 "National Food Safety Standard Food Additive Use Standard" strictly restricts the amount of glycerin used as a food additive raw material, using glycerin as a fermentation raw material for large-scale fermentation to produce functional red Qu has not been reported yet

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