The invention provides a special makeup remover for minimizing pores and moistening skin. The makeup remover is prepared from raw materials of components in percentage by weight as follows: 5%-20% of a surfactant, 5%-20% of a moisturizer, 2%-5% of salicylic acid, 0.5%-2% of a pot marigold extract, 0.5%- 1% of a seaweed extract, 1%-3% of a tea extract, 1%-3% of pentapeptide, 0.5%-2% of vitamin A, 0.01%-0.02% of methylisothiazolinone, 0.2%-1% of a coenzyme Q10, 0.1%-0.5% of sodium citrate and the balance of deionized water. The makeup remover is prepared from four components including salicylic acid, the pot marigold extract, the seaweed extract and the tea extract which have effects of shrinking and minimizing the pores, the four components are matched for use and have the more excellent effect than one single component, the pore minimizing effect is very significant, and besides, the makeup remover removes makeup thoroughly, is free of residues, irritation and oily feeling and can effectively prevent the skin from ageing, moisten and tender the skin and smooth the pores. Meanwhile, the invention further provides a preparation method of the makeup remover.