Microcapsule production technology

Abstract

The invention discloses a microcapsule production technology including five steps of preparation of a wall material solution, emulsification mixing of a core material and a wall material, ultrasonic embedding, homogeneous dispersion and micro capsule spray drying. The preparation technology has the advantages of simple operation, selection of the reasonable wall materials such as octenyl succinic starch ester, seaweed gum, carrageenan and the like, easily obtained raw materials, wide scope of application, safe and reliable use, capability of well preventing the volatilization, oxidation or inactivation of instable raw materials, and effectively preventing the release of the core material, by selection of a suitable emulsifier and stirring speed, the micro capsule embedding rate is improved; microcapsule is prepared by spray drying method, and the microcapsule production technology is high in production capacity, simple in technology, and suitable for continuous industrial and automatic production.

Description

【Technical field】 [0001] The invention relates to the technical field of medicine production technology, in particular to the technical field of a microcapsule production technology. 【Background technique】 [0002] Microcapsule refers to a polymer shell and a micro container or package. In recent years, some experts have also classified microcapsules into capsules. Microcapsules refer to the use of natural or synthetic polymer materials to wrap medicine powder particles or medicine liquid droplets into tiny capsules with a diameter of 1-5000 μm. The technique is called microencapsulation and the product is called microcapsules. [0003] Microcapsules are small spherical vesicles with a certain degree of permeability. The outer layer is a semipermeable membrane, and the inner layer is a liquid core, which is composed of a core material and a wall material. The significance of microencapsulation lies in: ①It can effectively reduce the reactivity of external environmental fac...

AI Technical Summary

Problems solved by technology

The microcapsule production process generally has the defects of complex preparation process, unreasonable selection of wall materials, inability to prevent volatilization of unstable raw materials, and fast release of core materials

In addition, existing problems also include the high cost of wall materials and the safety of auxiliary materials. It is necessary to actively look for wall materials that are easy to get, cheap, widely applicable, and safe for humans and the ecological environment; the effect of stirring speed on the particle size of microcapsules The stirring speed in the emulsification stage should not be too fast, and the high speed will also cause a large amount of foam in the system, which will reduce the strength of the capsule; if the stirring speed is too slow, the core material will not be emulsified, and the embedding rate and release performance of the product will be greatly affected. Influence; the drying temperature of microcapsules has a great influence on the performance of microcapsules. The reason is that during drying, if the temperature is too low, the product strength will decrease, and storage will easily cause adhesion and agglomeration. If the temperature is too high, the wall material will melt and the core material will be easily released.