115 results about "Graft transplant" patented technology

A hair transplantation method and apparatus utilizes a stereotactic robot, which includes a robotic arm, having a hair follicle introducer associated with the robotic arm.

We disclose an implantable prosthetic heart valve, comprising: a valve body comprising an orifice member, wherein the orifice member comprises an external groove; a sewing cuff; a sewing cuff retaining member seated within the external groove of the orifice member and coupling the sewing cuff to the orifice member; a tubular vascular graft; and a graft retaining member seated within the external groove of the orifice member and coupling the tubular vascular graft to the orifice member.

Devices and methods for applying tension to an area of skin, in particular for follicular unit removal and implant in a hair transplantation procedure are provided. The devices may include a frame with at least two skin contact members that hold to the skin. Also disclosed are various ways to apply a force displacing the skin contact members apart, thus creating tension in the skin therebetween. The devices and methods may incorporate suction that helps the skin contact members securely hold to the skin. Barbs or microbarbs also may be used to help secure the skin contact members to the skin. The frame may surround the skin area with tensile forces applied outward in multiple directions, or the frame may be a bifurcated pair of fingers that applies tension substantially uni-directionally. Adjusting members and indicators may be provided to control and display the magnitude of tensile force applied to skin. The tensioning devices and methods may be incorporated into a robotic hair transplantation system.

The harvesting of hair for a hair transplant procedure employs a hollow drill with an imaging system which permits alignment of center of the cutting edge of a hollow tube with the axis of the follicular unit to be removed. The diameter of the hollow tube is chosen such that when properly aligned, a follicular unit is removed without damaging critical anatomical portions of the follicles. In one embodiment, a medium in either liquid or vapor form is introduced to cool or freeze the skin over the surface of the selected follicular unit. In another embodiment, suction is applied to aid in the removal of the excised follicular unit. In still another embodiment, a robotic arm is employed to position the hollow needle in each instance. In another embodiment, an electrical current or heat is applied to kill the shaft of the selected follicular unit without its removal.

Methods and systems are provided useful in various procedures, including hair harvesting and implantation, and further including computer-implemented and / or robotic hair transplantation. Methodologies are provided which enable a tool, such as a hair harvesting or a hair implantation tool, to proceed at least under a partial computer control in a selected direction of travel along a donor or recipient area of the patient, as well as changing direction of travel based on desired harvesting and / or implantation criteria.

A hair transplantation method and apparatus utilizes a robot, which includes a robotic arm, having a hair follicle effector associated with the robotic arm.

A stent-graft is provided that includes a bifurcated stent adapted for placement at the bifurcation of a bifurcated body lumen. The stent-graft further includes a graft that lines or covers at least part of the bifurcated stent. The graft defines a fluid passageway from the unbifurcated portion into one of the bifurcated stent branches. A closure prevents fluid from flowing through the second of the branches and into the other branch of the body lumen.

Methods and systems are provided useful in various procedures, including hair harvesting and implantation, and further including computer-implemented and / or robotic hair transplantation. Methodologies are provided which enable selection of follicular unit harvesting or implanting sites. In various cases, such selection may be made using a lowest and closest method, overlap-based methods, position-based methods, pattern-based methods, and / or a combination of these methods. In various combinations of the methods, the output selection from one of the methods may be used as an input for one of the other methods.

A tape-reinforced tubular vascular graft formed of sintered fluoropolymer(s), such as expanded, sintered PTFE. The graft includes a base graft and a reinforcing tape applied thereto. The tape may be spirally wrapped about the graft or spirally wrapped into a tube about a cylindrical mandrel and then applied to the exterior of the graft. Radial shrinkage of the combined base graft and tape, or of the reinforcing tape tube, renders the vascular graft subsequently radially enlargeable by more than 5%, without tearing or breaking of the reinforcement tape layer of the graft. Radially enlargeable grafts of the present invention may be combined with various types of stents or anchoring systems, to form endovascular graft devices which are transluminally insertable and implantable within the lumen of a host blood vessel. Alternatively, radially enlargeable grafts of the present invention may be implanted by way of traditional surgical graft implantation techniques, without any radial enlargement of the graft at the time of implantation, so as to take advantage of the improved strength properties and suture-holding properties of the radially-shrunken tape-reinforced grafts of the present invention.

This multi-bladed scalpel addresses the problem of making many small incisions in very close proximity (as close as 0.030'' / 0.75 mm) to each other, to facilitate hair transplantation. With this device, it is possible to make multiple incisions in such proximity. With the blades mounted parallel to each other, at the desired spacing, each incision does not intersect neighboring incisions, so the follicles placed in each incision will be surrounded by the maximum amount of undisturbed tissue to promote revascularization-capillary growth to provide a blood supply to each transplanted follicle. CNC machining techniques are used to create the blade holders with blade mounting sites created at the desired proximity. Medical grade epoxy is used to mount the blades, which are mounted parallel to each other. Holes are drilled so the tips of the blade group are located in a plane at an angle with respect to the blade holder for ergonomic reasons

An implantable, varied-diameter graft is seamlessly flat-woven to provide a seamless, varied-diameter graft. The graft includes a flat-woven tubular portion having opposed first and second tubular ends with a contiguous bulbous woven section therebetween. The bulbous woven section has opposed first and second open ends with the first bulbous end being contiguous with the first tubular end. The second bulbous end is contiguous with the second tubular end. The first tubular end has a first number of warp yarns interlaced with a plurality of fill yarns in a woven pattern to define a first flat-woven tubular diameter. The second end has a second number of warp yarns interlaced with a plurality of fill yarns in a woven pattern to define a second flat-woven tubular diameter. The bulbous section has a third number of warp yarns interlaced with a plurality of fill yarns in a woven pattern to define a third flat-woven tubular diameter. The third number of warp yarns is greater than either of the first or said second number of warp yarns. Further, the third number of warps yarns are engagingly interlaced at the first bulbous end and disengagingly interlaced at second bulbous end to provide a seamless implantable graft having a third diameter being greater than either of said first or said second diameters.

Systems and methods for creating a treatment plan for cosmetic procedures, for example, a hair transplantation procedure, are provided. The treatment plan automatically modifies or generates one or more proposed harvesting or implantation sites within a first hair element based on one or more parameters in one or more second hair elements. Various techniques and methods described in the application provide for improved planning of a natural looking hair.

The present invention provides use of soluble CTLA4 mutant molecules which bind with greater avidity to the CD80 and / or CD86 antigen than wild type CTLA4 or non-mutated CTLA4Ig in the treatment of immune disorders associated with graft transplantation.

A disposable needle hair transplanter includes: a plunger structure having an outer barrel defining a passage, a plunger assembly having at least one push needle movable within the passage of the outer barrel, and a hair transplantation depth controller drivingly connected with the plunger assembly via a link; a needle having a needle seat connected with the outer barrel and at least one needle tube in which a hair follicle is loadable, the hair transplantation depth controller serving to restrict the depth by which the needle tube is thrust into the scalp; and a hair follicle depth controller having a cylindrical structure fitted around the needle seat and a shaft tube connected with the cylindrical structure and coaxially disposed around the needle tube. The hair transplantation depth controller is disposed around the shaft tube and movable along the shaft tube toward or away from the scalp.

Methods and systems are provided useful in various procedures, including hair harvesting and implantation, and further including computer-implemented and / or robotic hair transplantation. Methodologies are provided which enable a tool, such as a hair harvesting or a hair implantation tool, to proceed at least under a partial computer control in a selected direction of travel along a donor or recipient area of the patient, as well as changing direction of travel based on desired harvesting and / or implantation criteria.

The present invention relates to an apparatus for automated hair transplantation through the well-known extraction technique of capillary units or FUE, comprising the morphological analysis of hair follicles in real-time by means of artificial vision, mapping of points for extraction and implant, simulation of the final result, a system of local anaesthesia, global, simultaneous or in sequential phases, at least one articulated mechanical arm associated with a tool for differentially extracting and implanting hair follicles.The present invention is useful to reduce the time and cost associated with the intervention, improve the quality of the operation and the final result, in terms of capillary density, contemplating the study of cell differentiation of follicles with the required estimate of time required regarding the growth. Minimizes the positional discomfort of the patient, the pain associated with the administration of anaesthesia, among other inconveniences usually experienced by the patient in this type of intervention. The present invention is useful for diagnosis, treatment and hair transplantation procedures.

A device and method for applying tension to an area of skin, in particular for follicular unit removal and / or implantation in a hair transplantation procedure, is provided. The tensioning device comprises at least one body surface grabber capable of engaging the body surface, and the tensioning device is configured to be able to create tension on a body or skin surface by simply displacing the tensioning device as a whole in one general direction. The tensioning device may be secured, for example, to a patient chair.

A method for repairing a damaged myocardium in a mammal, comprising: a) providing a three-dimensional porous polysaccharide matrix; b) introducing mammalian cells into said matrix; c) growing said cells in said matrix in vitro, until a tissue-engineered biograft is formed, comprising a contracting tissue; and d) transplanting the tissue-engineered biograft onto the myocardial tissue or myocardial scar tissue of said mammal, optionally previously removing scar or dead tissue from the site of implantation.

The present invention relates to a structure of a natural or artificial hair for a hair transplant and, more particularly, to a processed structure of a natural or artificial hair for transplantation, comprising: a number of fixing cut parts formed lengthwise on the outer circumferential surface line of a lower end part of a natural or artificial hair to be transplanted to a scalp of a person, that is, on the outer circumferential surface line of an insertion part to be inserted inside the scalp, the fixing cut part cut perpendicular to the outer circumferential surface line of the insertion part and formed along the outer circumference surface of the insertion part while having a predetermined angle toward the center of the hair.

Compositions containing purified collagen biomaterial derived from tissues, for example, insoluble amnion, soluble amnion, soluble chorion of the human placenta, are provided. The collagen compositions can be used to promote wound healing, promote tissue regeneration, prevent or reduce scarring, reduce local inflammation, minimize tissue rejection, promote graft integration. Methods for using the collagen composition as a biomaterial implant for dermal filling, skin grafting, and hair transplantation are also provided.

This multi-bladed scalpel addresses the problem of making many small incisions in very close proximity to each other, to facilitate hair transplantation. With this device, it is possible to make multiple incisions in such proximity. With the blades mounted parallel to each other, at the desired spacing, each incision does not intersect neighboring incisions, so the follicles placed in each incision will be surrounded by the maximum amount of undisturbed tissue to promote revascularization—capillary growth to provide a blood supply to each transplanted follicle. CNC machining techniques are used to create the blade holders with blade mounting sites created at the desired proximity. Medical grade epoxy is used to mount the blades, which are mounted parallel to each other. Blade mounting holes are drilled so the tips of the blade group form a planar array of interdigitated and offset blades at an angle with respect to the handle.

Devices and methods for applying tension to an area of skin during various cosmetic or dermatological procedures, in particular for follicular unit removal and / or implantation in a hair transplantation procedure, are provided. The systems and methods utilize a segmented structure configured to conform to the body surface of various sizes, shapes and / or textures, thus allowing for customization in order to fit a variety of persons. In some embodiments, the tensioning device may be temporary secured, for example, to a patient chair.

Devices and methods for applying tension to an area of skin are provided, for example, for follicular unit removal and implant in a hair transplantation procedure. The devices may include a frame with at least two skin contact members that hold to the skin. Also disclosed are various ways to apply a force displacing the skin contact members apart, thus creating tension in the skin. The devices and methods may incorporate suction, and / or barbs or microbarbs. The frame may surround the skin area with tensile forces applied outward in multiple directions or substantially uni-directionally. Adjusting members and indicators may be provided to control and display the tensile force applied to skin. The tensioning devices and methods may be incorporated into a robotic hair transplantation system.

Disclosed is a hair transplanter which may finely adjust and set the length of a hair transplantation tool, into which a hair root is inserted, according to thicknesses of skin tissue layers within the scalps of individuals during hair transplantation and thus be conveniently used.

Provided is a hair transplanter having high precision in hair transplantation which may finely adjust the length of a hair transplantation needle unit, into which a hair root is inserted, according to thicknesses of skin tissue layers within the scalps of individuals during hair transplantation. The hair transplanter includes a central rod including a guide hole, a hair transplantation needle unit inserted into the guide hole of the central rod, a central case body including a conical cover and a waist part having a small diameter, formed at the front end thereof, and a fixing cover and a tuning cover, formed at the rear end thereof, a core shaft configured to push a hair to be transplanted, which is inserted into the hair transplantation needle unit, and a pressing button including an adjustment lever to fix the core shaft and a lock nut to fix the adjustment lever.

Methods and composition are provided for diagnosing or predicting the status or the outcome of a graft transplant. In some embodiments, the presence or absence of one or more proteins recognizing a non-HLA / non ABO antigen is determined. The obtained result is then employed to diagnose or predict the status or outcome of the graft transplant. Also provided are compositions, systems and kits that find use in practicing the subject methods.

The present invention discloses a hair transplanter. A needle to be inserted into a scalp has a pointed end portion to reduce damage of the scalp, and a guide plate is adhered to an end portion of a sliding unit reciprocating in the longitudinal direction of the needle outside the needle, in order to prevent hair roots from being separated at the time of the separation of the needle. As a result, the hair roots inserted into a needle insertion groove are not damaged and are naturally settled in the scalp, thereby stably performing the hair transplantation.

The invention discloses a soluble microneedle for promoting hair growth. The microneedle comprises a base, a soluble polymer needle body located on the base and a needle tip carrying a hair growth promoting substance. The invention discloses a preparation method of a soluble microneedle for promoting hair growth. The preparation method comprises the following steps: 1) preparing a PDMS microneedlearray mold; 2) preparing a soluble polymer aqueous solution containing substances for promoting hair growth; and 3) preparing the soluble polymer microneedle array loaded with the substance for promoting hair growth, which can solve the technical problems of low transdermal rate, non-uniform distribution, pain in the subcutaneous injection process of interleukin 2, large side effect of a finasteride oral administration mode and high hair transplantation price of the existing external medicine.

Tools and methods are provided for removing follicular units from a body surface while improving retention of the follicular units in the removal tool. The removal tool is configured to accommodate a retention member. The retention member may comprise pivotally movable elements which retain the follicular unit in the removal tool. The described tools and methods are especially useful for harvesting follicular units from a body surface in a hair transplantation process.

A hair transplantation robot comprises a robot body (1), robot limb structures (2), a robot neck structure (3) and a robot head structure (4). The robot limb structures (2) can be hinged to the robotbody (1), the robot neck structure (3) is connected to the upper portion of the robot body (1), and the robot head structure (4) can be hinged to the robot neck structure (3); each robot limb structure (2) is provided with an operation end (5) arranged at the front end, the robot neck structure (3) serves as a fixing device for fixing the patient's head in hair transplantation, and the robot headstructure (4) serves as a control and image acquisition terminal in hair transplantation. The hair transplantation robot integrates various functions such as hair transfer, hair transplantation, hairfollicle detection and diagnosis, and is powerful in function, flexible and easy to operate and capable of meeting various demands of hair transplantation patients.