131 results about "Linoleates" patented technology

A resistant to body fluids, organic oil-based topical transdermal composition for the alleviation and treatment of infant skin conditions, including, dry, sensitive, chapped, cracked, itching reddened, and flaking skin, as well as infant skin infirmities associated with eczema, dermatitis, and diaper rash, which has as main constituents, organic oil lipids, vitamin A, tocopheral linoleate, and tincture of benzoin, in an organic beeswax emulsifying base.

Conjugate linoleic acid or cnojugate linoleate microcapsule consists of wall material, capsule core, assistant, surfactant and plasticizer. Capsule core is added into wall material water solution and emulsified while adding assistant, surfactant and plasticizer; and the microcapsule product is obtained through spray drying. Great amount of experiment shower that the product has high antioxidant performance and high store stability, can mask bad smell, avoid mutual effect of different incompatible food components and decrease degradation reactions and reach controlled release. The present invention may be used in health food, food additive and feed additive and has health functions of anticancer, resisting arteriosclerosis, regulating metabolism, strengthening body's immunity, regulating blood sugar, etc.

Methods of determining levels of unbound metabolites are disclosed. Probes derived from fatty acid binding protein muteins are described that bind preferentially to a number of unbound metabolites including oleate, stearate, linoleate, palmitate, arachidonate and unconjugated bilirubin. A profile for a patient is determined using one or more of the described probes. The profile is useful in diagnosis of disease, particularly myocardial infarction, non-alcoholic fatty liver disease (NAFLD), diabetes, stroke, sepsis and neonatal jaundice. The responses of multiple probes to a test sample are used to classify the degree of acute coronary syndrome by comparison to multi-probe profiles generated from unstable angina, non ST elevation myocardial infarction, and ST elevation myocardial infarction.

An improved, resistant to body fluids, and useful organic oil-based topical transdermal composition for the swift alleviation and treatment of infant skin conditions, including, dry, sensitive, chapped, cracked, itching, reddened, and flaking skin, as well as infant skin infirmities associated with eczema, dermatitis, and diaper rash, which has as main constituents, organic oil lipids, vitamin A, tocopheral linoleate, and tincture of benzoin, in an organic beeswax emulsifying base.

A detection method for tea seed oil adulteration based on ratio of main fatty acids obtains the contents of main fatty acids in pure tea seed oil and adulterated tea seed oil samples by applying gas chromatography and mass spectrometry technology (GC-MS technology), and intuitively presents the distribution characteristic of fatty acids of grease-adulterated pure tea oil by adopting a two-dimensional diagram of methyl cis-oleate / methyl cis-linoleate and methyl palmitate / methyl stearate, so as to qualitatively identify adulteration of tea oil.

The present invention comprises a blend of polyester and a partially aromatic polyamide with an ionic compatibilizer and a cobalt salt. This blend can be processed into a container that has both active and passive oxygen barrier and carbon dioxide barrier properties at an improved color and clarity than containers known in the art. The partially aromatic polyamide is preferably meta-xylylene adipamide. The ionic compatibilizer is preferably 5-sodiumsulfoisophthalic acid or 5-zincsulfoisophthalic acid, or their dialkyl esters such as the dimethyl ester (SIM) and glycol ester (SIPEG). The cobalt salt is selected form the class of cobalt acetate, cobalt carbonate, cobalt chloride, cobalt hydroxide, cobalt naphthenate, cobalt oleate, cobalt linoleate, cobalt octoate, cobalt stearate, cobalt nitrate, cobalt phosphate, cobalt sulfate, cobalt (ethylene glycolate), or mixtures of two or more of these. The partially aromatic polyamide is present in a range from about 1 to about 10 wt. % of said composition. The ionic compatibilizer is present in a range from about 0.1 to about 2.0 mol-% of said composition. The cobalt salt is present in a range from about 20 to about 500 ppm of said composition.

The invented prodn. process contains steps of: (1) raw material algal bloom blue green algare is concentrated, dewatered, dried and crushed to obtain algare powder; (2). said powder is soaked in mineral ether at room temp. to break the cells, and continuously soaked after a night, refluxing in water bath, then removing leavings of the cell to obtain gamma-linoleates mixed ester; (3). said ester is saponified after adding saponifier in water bath, then cooled to room temp., (4). adjusting said solution pH value to 3-4, then methoxycarbonylation and urea packing reaction to abtain gamma-linoleic acid. Advantages are: simple process, high obtg. rate, easy to obtain raw material, with social, environment and economic benefits.

The invention discloses multiple-plant-extract lip pomade and a preparation method thereof. The multiple-plant-extract lip pomade contains the following raw materials in parts by weight: 19 parts of olive squalane, 14 parts of diisostearyl alcohol malate, 5 parts of dimeric pentaerythritol tri-polyhydroxyl stearate, 5 parts of jojoba esters, 5 parts of tridecanol trimellitate, 5 parts of caprylate / decanoate triglyceride, 5 parts of meadowfoam seed oil, 5 parts of adansonia digitata tree seed oil, 5 parts of phytosterol oleate, 5 parts of C10-30 acid cholesterol / lanosterol mixed ester, 4 partsof polyethylene, 3 parts of candelilla wax, 3 parts of hydrogenated castor oil dimeric linoleate, 3 parts of polyglycerol-2-tri-isostearate, 2.5 parts of beeswax, 2.5 parts of earth wax, 4 parts of humectant, 2 parts of emollient, 2 parts of prunus avium seed oil, 0.5 part of tocopherol and 0.5 part of antioxidant. The multiple-plant-extract lip pomade has very good repairing, moisture preservingand cheilogramma dispelling actions and can be used for durably nourishing and relaxing skin and keeping lip skin healthy.

Conjugate linoleate microcapsule consists of conjugate linoleate, other aliphatic salt, wall material, solvent and antioxidant. Mixed aliphatic salt powder containing conjugate linoleate is suspended on fluidized bed, wall material is dissolved in solvent and sprayed into the fluidized bed, and the microcapsule product is obtained through drying. Great amount of experiment shows that the product has high antioxidant stability and long shelf life, is easy to use, and may be controlled to release and to mask bad smell.

The invention discloses a skin care product with functions of relieving allergy, relaxing, repairing and improving sebum film and a preparation method thereof. The skin care product comprises the following components: cynanchum grandiflorum extract, trehalose, mother chrysanthemum extract, euphorbia sunflower extract, peony root extract, honeysuckle flower extract, herba Taraxaci rhizome / root extract, herba violae extract, aloe barbadensis leaf juice, dual-behenyl alcohol / isostearyl alcohol / phytosterol dipolyoleyl alcohol dimerized linoleate, oligopeptide-1, bisabolol, ceramide-3 and tocopherol (vitamin E). The skin care product has a plurality of purposes, which not only can relieve the allergy and relax, but also can repair and improve the sebum barrier; meanwhile, the component combination is water-soluble, so that the composition is not limited by the product dosage form, and can be added into aqua, emulsion, cream, essence and the like; the skin care product has effects in relieving allergy, relaxing, repairing, and improving sebum film; the skin care product completely overcomes the obvious defect of single function of commercial products.

An edible composition for ingestion by mammals, especially by humans, that includes a fat-based blend containing: (a) at least one triglyceride-based fat, (b) a low level of diglycerides, for example, less than 3% by weight of diglycerides, e.g., diacylglycerol (DAG), and (c) at least 2% and in some instances at least 5% by weight of a mixture of fatty acid Ester Phytosterols (EPs), in which at least 65% by weight of the fatty acid EPs are Monounsaturated (oleate)-Ester Phytosterols (MEPs), and less than 20% by weight of the fatty acid EPs are Polyunsaturated (linoleate+alpha-linolenate)-Ester Phytosterols (PEPs). The increased proportion of MEPs and decreased proportions PEPs and diglycerides substantially increase the oxidative stability index (OSI), shelf life, and health benefits of the above mixture of fatty acid EPs, while providing an advantageous melting temperature and desirable mouth feel for this mixture of fatty acid EPs.

The invention concerns the use of certain compounds related to fatty acids to control nematodes that infest plants or the situs of plants. Nematodes parasitizing animals can also be controlled using the methods and composition of this invention. The useful compounds are inhibitors of nematode delta-12 fatty acid desaturases and can be, for example, from C16 to C20 in length. A feature of these compounds is that their inhibitory effect on the activity of a nematode delta-12 desaturase, or on the viability or fecundity of a nematode, is smaller in the presence of the product of a delta-12 fatty acid desaturase (e.g., linoleate) than in the presence of the substrate of the enzyme (e.g., oleate).

A nail polish remover is formulated from a combination of solvents derived from naturally occurring materials, which combination consists essentially of a (i) a major proportion by weight (“by wt”) of esters of fatty acids having from 16 to 18 carbon atoms wherein the content of linoleic acid ester in the source vegetable oil is less than 60%, and (ii) a minor proportion by weight of a lower (C1–C5) alkyl lactate. The nail polish remover is highly effective yet has good skin conditioning properties, is non-toxic and non-flammable. A visible residue several micrometers thick provides a desirable gloss on the cleaned nails unless it is washed off.

An endogenous oil extracted from Brassica seeds is disclosed that contains, after crushing and extraction, greater than 86% oleic acid and less than 2.5% α-linolenic acid. The oil also contains less than 7% linoleic acid. The Brassica seeds are produced by plants that contain seed-specific inhibition of microsomal oleate desaturase and microsomal linoleate desaturase gene expression. Such inhibition can be created by cosuppression or antisense technology. Such an oil has a very high oxidative stability in the absence of added antioxidants.

The invention belongs to the technical field of cosmetics. In order to improve the gloss of lipstick, the invention discloses a lipstick and a preparation method thereof, wherein, the lipstick comprises the following components in percentage by mass: polyethylene wax: 4-6%; Candlestick wax: 0.5-1%; Beeswax: 2-4%; Pure floor wax: 5-8%; Pentaerythritol tetraisostearate: 15-20%; Polyisobutylene: 4-6%; Polyglycerol-2 triisostearate: 4-7%; Hydrogenated polyisobutylene: 5-10%; Jojoba Seed Oil: 1-3%; Shea butter: 3-5%; Phenyl silicone oil raw material: 15-20%; Double-Behenyl alcohol or isostearyl alcohol or phytosterol dimeric linoleic alcohol dimeric linoleic acid ester alcohol: 10-15%; CI77891:1%-10%; CI45410:1%-10%; CI15985:1%-10%; Tocopheryl acetate: 0.5%-1%; and Phenoxyethanol: 0.1%-0.5%. The lipstick of the invention has the advantage of high gloss.

The invention relates to the field of personal care products, in particular to a lipophilic personal care composition and use thereof. The lipophilic personal care composition comprises, by weight percentage, 1-10% of polyglyceryl 2-isostearate / dimer dilinoleic acid copolymer, 1-10% of hydrogenated castor oil dimer linoleate, 25-50% of isopropyl myristate, 10-50% of castor oil, 0.01-2% of bromic acid red pigment and 5-35% of conditioner. The composition has excellent dispersibility and stability in lipstick and excellent moisturizing and conditioning effects, is bright and beautiful in appearance and color, and is friendly and non-irritating to the human body.

The present invention discloses a preserving health edible oil and a technique for producing the same which selects seed oil as base material, listerize in high temperature, perfuming, flavourings andcooperating with edible chemical industry raw material for stirring, depositing and filtering. A raw material has proportioning by weight as follows: any one or more than two of rape oil, soya-bean oil, maize oil, sunflower oil, oil of groundnuts, gingelly oil and cotton seed oil with 94-98% content; fennel, chinese red pepper, cloves, citrus reticulata blanco and common ginger root five powderedflavours with 0.5-2% content; lactic acid with 0.2-1% content; edible safflower oil with 1-3% content. The edible safflower oil contains 50% linoleate. The edible oil has advantages of simple prescription, easy producing, short process flow, simple equipment. The edible oil is widely used for cooking various food and dishes which has perfect quality, particular flavour, low cost, economy and practical, storability, and has higher nutrition value and health-care action. The contained lactic acid and linoleate have function of preventing disease of nonnasality, esophagus and gastrointestinal, also have effects for dredging vascular, reducing cholesterin in blood and preventing cardiovascular and cerebrovascular diseases.

The invention discloses a gapatite demagnesia reverse flotation collector agent. The gapatite demagnesia reverse flotation collector agent comprises preparation materials that alpha sulfonated saturated fatty acid salt, alpha sulfonated oleate or alpha sulfonated linoleate, fatty acid sope, malkyl sulfate or sodium alkyl benzene sulfonate, fatty alcohol polyoxyethylene ether dium sulfate, keroseneand water; the preparation method is to mix the materials together in a certain proportion; with a mixture as the standard one part, the mixture is added into a certain proportion water, then the mixture is stirred, and the collector agent is obtained. The gapatite demagnesia reverse flotation collector agent is low in preparation cost, and the collector agent can be carried out under 5-30 DEG Cof ore pulp temperature, and the collector agent is good in selectivity, strong in collection ability, and the flotation foam is good and non-sticky.

A conjugated magnesium linoleate preparation is prepared through reaction between the conjugated linoleic acid and the aqueous solution of the hydroxide or carbonate of alkali metal, adding magnesium salt and reaction.

The invention discloses a catalyst for injecting air into thick oil for oxidation and viscosity reduction, and belongs to the field of catalysts. The catalyst for injecting air into the thick oil for oxidation and viscosity reduction is prepared from 59.8%-70.2% of polymer carriers, 5.7%-8.3% of metal hydroxide, 9.7%-12.3% of metal potassium linoleate, 2.7%-5.3% of benzoic acid and 11.7%-14.3% of petroleum sulfonate. The catalyst for injecting air into the thick oil for oxidation and viscosity reduction has the advantages that the structure of the thick oil is improved, the viscosity of the oxidized thick oil is reduced, and therefore the oil recovery rate is increased through injecting air into the thick oil for catalytic oxidation.

The invention discloses a memantine insoluble salt sustained-release injection and a preparation method thereof. The memantine insoluble salt sustained-release injection is characterized by being prepared from the following materials by mass percentage: 1% to 30% of memantine insoluble salt as an active ingredient, 0.1% to 10% of stabilizer , 0% to 1% of pH adjuster, 0.1% to 5% of isotonic regulator and 60% to 98% of injection water; the memantine insoluble salt includes one of memantine-oleate, memantine-linoleate, memantine-linolenate, memantine-arachidonate, memantine-stearate, memantine-laurate, memantine-tannate, memantine palmitate, memantine-pamoate, and memantine-furanate. An insoluble salt technology is adopted to prepare the memantine insoluble salt, and the drug release time isprolonged by reducing the solubility of the drug. Compared with memantine hydrochloride, the solubility of the memantine insoluble salt is reduced by 40 to 600 times, and the memantine insoluble saltcan be slowly released for several days to several weeks.

An edible composition for ingestion by mammals, especially by humans, that includes a fat-based blend containing: (a) at least one triglyceride-based fat, (b) a low level of diglycerides, for example, less than 3% by weight of diglycerides, e.g., diacylglycerol (DAG), and (c) at least 2% and in some instances at least 5% by weight of a mixture of fatty acid Ester Phytosterols (EPs), in which at least 65% by weight of the fatty acid EPs are Monounsaturated (oleate)-Ester Phytosterols (MEPs), and less than 20% by weight of the fatty acid EPs are Polyunsaturated (linoleate+alpha-linolenate)-Ester Phytosterols (PEPs). The increased proportion of MEPs and decreased proportions PEPs and diglycerides substantially increase the oxidative stability index (OSI), shelf life, and health benefits of the above mixture of fatty acid EPs, while providing an advantageous melting temperature and desirable mouth feel for this mixture of fatty acid EPs.

The purpose of this invention is: new selenohydroxy acid compounds and their derivatives; their process for the preparation; use of the said new compounds as precursors of L(+)-selenomethionine and / or source of selenium in human or animal nutrition, in cosmetics and pharmaceutics; and nutritional, cosmetic and pharmaceutical compositions containing them. The new compounds that are the subject of this invention satisfy the general formula (I): in which n=0, 1 or 2, R1=OH, OCOR3, OPO3H2, OPO(OR4)(OR5), or OR6, R2=OH, R3, or NHR7, R3=particularly alkoxyl (C1-C26), ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6a and 6b, S-cysteinyl, S-glutathionyl, carnitoyl, lipids, polyols, OR4=OR5=particularly alkoxyl (C1-C26), ceramide 1, ceramide 2, ceramide 3, ceramide 4, ceramide 5, ceramide 6a and 6b, S-cysteinyl, S-glutathionyl, carnitoyl, lipids, polyols, OR6=pyruvate, lactate, citrate, fumarate, maleate, myristate, palmitate, stearate, palmitoleate, oleate, linoleate, natural fatty acids, or 13-cis retinoate R7=H, alkyl, natural amino acids, or natural amines.

The invention belongs to the technical field of medicines. The invention relates to a hydroxycamptothecine linoleate micromolecular prodrug and construction of self-assembled nanoparticles. Accordingto the invention, the disulfide bond bridged hydroxycamptothecine linoleate prodrug is designed and synthesized, and the prodrug is self-assembled into the nanoparticles by adopting a one-step nano precipitation method, so that an efficient and low-toxicity drug delivery system which is good in stability, high in drug loading capacity, low in toxic and side effects, accumulated in tumor parts, capable of selectively releasing drugs and high in anti-tumor activity is obtained, the preparation process is simple, and industrialization is easy. Meanwhile, a hydroxycamptothecine solution is used asa contrast, and morphological characterization of the prodrug self-assembled nanoparticles and in-vitro and in-vivo anti-tumor effects are investigated. More choices are provided for designing camptothecin drug nano-preparations with high drug loading capacity, a new strategy is provided for developing an efficient and low-toxicity drug delivery system, the clinical service life of first-line chemotherapeutic drugs is prolonged, and the urgent requirement for high-end cancer chemotherapeutic preparations in clinic is met.

The invention discloses a long-acting makeup-maintaining moistening repair emulsified lipstick and a preparation method thereof. The lipstick comprises the following components: polyglycerol-2-diisopstearate, cetyl ethyl hexanoate, ethylhexyl palmitate, hydrogenated castor oil dimer linoleate, a hippophae rhamnoides extract, a hibiscus mutabilis extract, a centella extract, a polygonum cuspidatumroot extract, a scutellaria baicalensis root extract, a glycyrrhiza glabra root extract, a chamomilla recutita flower extract, a rosmarinus officinalis leaf extract and the like. A used formula systemis different from a conventional method. A conventional lipstick is prepared by mixing oil, grease, wax, toner and the like, and a water system is not contained, so many low-water-activity matters cannot be added to a product. The conventional method is broken by using a combination technology related to raw materials of the oil, the grease, the wax, the toner, an emulgator, a water activity matter and the like. The makeup-lasting, waterproof, oil-proof and difficult makeup-removing effects are realized, and multiple functions of moistening, moisturizing, and repairing and the like are integrated. The preparation method thereof is capable of realizing large-scale production.

The present invention provides modified TLR2 ligands useful for modulating inflammatory responses. In particular, the ligands comprise (a) a fatty acid di- or tri-linoleate and (b) a GM1-binding peptide. The linoleate provides the anti-inflammtory function, while the GM1-binding peptide facilitates endocytosis.

The invention discloses a method for degrading a triphenylmethane dye by utilizing recombinational lipoxygenase and application of the recombinational lipoxygenase rLOX-27853 in degrading the triphenylmethane dye. The amino acid sequence of the recombinational lipoxygenase rLOX-27853 is as shown in SEQ ID NO.2. The method for degrading the triphenylmethane dye by utilizing the recombinational lipoxygenase comprises the following steps: adding the recombinational lipoxygenase rLOX-27853 to a medium which contains sodium linoleate and the triphenylmethane dye to degrade the medium. The method disclosed by the invention obtains a novel prokaryotic lipoxygenase gene LOX-27853 by cloning from a pseudomonas aeruginosa ATCC27853 strain genome and realizes the heterogenetic high-efficiency expression of host bacteria in escherichia coli by utilizing a fermentation culture method, thereby efficiently catalyzing the degradation of the triphenylmethane dyes, namely aniline blue, malachite green and brilliant green.

The invention provides a sunscreen transparent lipstick which is prepared from the following components in percentage by weight: 90.1wt% of first component and 0.9wt% of second component, wherein the first component is a mixture of the following components: a mixture of dibutyl lauroyl glutamine, polyamide-3 and a bis-stearyl ethidene diamine / neopentyl glycol / stearyl alcohol hydrodimerized linoleate copolymer, C12-15 cholesteryl benzoate, heptyl undecylenate, benzophenone-3, ethylhexyl salicylate, homosalate, C10-30 acid cholesterol / lanosterol mixed ester, hydrogenated C6-20 polyolefin and dextrin isostearate; the second component is an auxiliary additive. The lipstick provided by the invention can pass through a three-month stability test, and is clear and transparent in appearance, good in sunscreen effect, high in melting point, good in moistening degree and difficult to break off.

Methods of determining levels of unbound metabolites are disclosed. Probes derived from fatty acid binding protein muteins are described that bind preferentially to a number of unbound metabolites including oleate, stearate, linoleate, palmitate, arachidonate and unconjugated bilirubin. A profile for a patient is determined using one or more of the described probes. The profile is useful in diagnosis of disease, particularly myocardial infarction, non-alcoholic fatty liver disease (NAFLD), diabetes, stroke, sepsis and neonatal jaundice. The responses of multiple probes to a test sample are used to classify the degree of acute coronary syndrome by comparison to multi-probe profiles generated from unstable angina, non ST elevation myocardial infarction, and ST elevation myocardial infarction.

The invention provides a method for preparing conjugated linoleic acid. The method comprises the following steps: reacting linoleate under catalysis of organic base of which the pKa is more than 11, thereby obtaining the conjugated linoleic acid ester. Furthermore, an ester exchange reaction can be carried out between the conjugated linoleic acid ester and glycerin or derivatives thereof, and conjugated linoleic acid glyceride is prepared. By utilizing the conjugated linoleic acid prepared by the invention, the reaction conversion rate is high, and the content of fatty acids in the conjugated linoleic acid product meets the related statutory and regulatory requirements.