The invention relates to an extraction process for large-scale production of a radix angelicae extract in a medicinal radix angelicae material. The extraction process is characterized by comprising the following steps: for primary refluxing, adding 10 parts by weight of coarse radix angelicae
powder into an extraction tank; adding 40-50 parts by weight of 75% to 85%
ethanol into the extraction tank; heating to the temperature of 60 DEG C; soaking for 1-1.5 hours and then stopping heating; soaking for 3 hours; heating again, controlling the temperature to be 75 to 78 DEG C and performing
reflux extraction for 1 hour; for secondary refluxing, adding 40-50 parts by weight of 75% to 85%
ethanol into the extraction tank, soaking for 1-1.5 hours at normal temperature, heating again, controlling the temperature to be 75 to 78 DEG C and performing
reflux extraction for 1 hour; combining the two extraction solutions, decompressing and concentrating; discharging when the
relative density of a radix angelicae extract is equal to 1.10 to 1.40. The extraction process is short in production period, high in production efficiency, low in production cost, complete in extraction, good in
environmental protection property and high in
safety coefficient. According to the process,
reflux extraction is performed twice; the production period is 1.8 day / batch; the extraction rate is 15% to 20%; the extract yield is relatively smaller than that of a
percolation process; the content of effective components in the extract is higher; the transfer rate of the effective components of the extract is above 70% based on
imperatorin.