High-purity mangiferin prepared from leaves and twigs of aquilaria sinensis and preparation method thereof

Abstract

The invention discloses high-purity mangiferin prepared from leaves and twigs of aquilaria sinensis and a preparation method thereof. The method comprises the following steps: on the basis of utilizing leaves and/or twigs of aquilaria sinensis as raw materials, extracting with an alcohol solution; after recovering alcohol at reduced pressure, carrying out water precipitation, alcohol precipitation, devitrification and the like so as to obtain a mangiferin crude product; and then recrystallizing to prepare the high-purity mangiferin. The method has the advantages that the leaves and twigs of aquilaria sinensis are used as the raw materials; the content of the mangiferin is high, and the variety and quantity of impurities are both low; the obtained high-purity mangiferin dose not contain allergic components, and the final product is high in quality and can be widely applied to the industries such as medicine, health care products and cosmetics; and the method has the advantages of simple, stable, practicable preparation process step, short production period, less labor consumption and low cost.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to high-purity mangiferin prepared from leaves and twigs of Akiras sinensis and a method thereof. Background technique [0002] Aquilaria sinensis (Lour.) Gilg is an evergreen tree of the genus Aquilaria Lam. in the family Thymelaeaceae. It is a unique tree species for us. It was approved by the State Council as a second-class national key protected wild plant in 1999. "2000 It is listed as Vulnerable in the IUCN Red List of Threatened Plants. White wood incense has high economic value and is mainly used to produce white wood incense. Its unscented wood can be used as ordinary wood or crushed as a raw material for burning incense. Respiratory diseases, heart disease, and angina pectoris also have good relief and therapeutic effects (Mei Quanxi et al., 2007). Its seed oil content reaches 68.5%, is much higher than other woody plants, can provide rich renewable raw materials for my...

AI Technical Summary

Problems solved by technology

[0008] 2. Mango leaves are generally used as raw materials. Because the tree is prone to worms, the use of pesticides often exceeds the standard, resulting in the prepared mangiferin containing organic pesticide residues;

[0009] 3. Mango leaves are generally used as raw materials, because the raw materials contain a large amount of organic acid allergens, which greatly restricts the application of mangiferin products extracted from them in the pharmaceutical, health care products, and cosmetic industries;

[0010] 4. The extraction process generally uses toxic organic solvents such as butanol and petroleum ether, which pollute the environment, and the prepared mangiferin products have residual organic solvents, which affect safety;

[0011] 5. The purity of mangiferin products generally obtained is low, and only one patent has reached 98%, but the process used in this patent is complicated and the cost is high

The existing mangiferin process is complex and difficult to operate; the use of various organic solvents and macroporous resins significantly increases production costs and affects safety

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