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Method for preparing composition containing 2-palmitin

A technology of palmitic acid glyceride and composition, which is applied in the field of composition preparation, can solve the problems of unfavorable environmental protection, low product purity, low product purity and the like, and achieves the effects of less by-products and simple preparation process

Inactive Publication Date: 2014-10-08
CABIO BIOTECH WUHAN CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But these methods are limited by raw materials, and the purity of product is all relatively low
Even if the content of palmitic acid in the 2-position is increased by random transesterification, the purity of the product is still not high due to the limitation of the total composition of palmitic acid
When such a composition is subjected to subsequent refining, a large amount of waste, such as sodium fatty acid, etc., will be generated, which is not conducive to environmental protection

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] (1) A palm oil is provided, the proportion of palmitic acid in the total fatty acids is 21.7%, and the content of 2-position palmitic acid is 15.6%. Among them, "2-position palmitic acid content" refers to the content of palmitic acid at the 2-position accounting for all the fatty acids at the 2-position, and its detection method refers to GB / T24894, the same below.

[0028] (2) Put 25g of palm oil, 1g of palmitic acid, and 0.5g of potassium hydroxide into a flask, stir and heat up to 170°C and keep it constant, and continue the reaction for 10 hours (transesterification, the same below), then add hexane After 50ml is fully dissolved, the fatty acid potassium is removed by centrifugation to obtain grease A.

[0029] (3) Mix 20 g of fat A and 20 g of oleic acid, place in a four-neck flask, stir and heat up to 68°C and keep it constant, add 2.4 g of sn-1,3-specific lipase, and reflux for 8 hours (directed transesterification, The same below), to obtain mixed oil B.

[0...

Embodiment 2

[0032] (1) Provide a kind of palm oil, its palmitic acid accounts for 22.8% of total fatty acid ratio, and 2-position palmitic acid content is 16.4%.

[0033] (2) Add 50 g of palm oil, 1 g of methyl palmitate and 0.5 g of lipase into the flask, stir and raise the temperature to 76° C. and keep it constant, and continue the reaction for 8 hours. After the reaction, fatty acid methyl ester was removed by dry fractionation to obtain fat A.

[0034] (3) Mix 40g of fat A and 20g of linoleic acid, put it in a four-neck flask, stir and heat up to 70°C and keep it constant, add 200ml of cyclohexane, add 2.4g of sn-1,3 specific lipase, and reflux reaction After 7 hours, mixed oil B was obtained.

[0035] (4) Purify the mixed oil B. The purification steps include but are not limited to: filter to remove lipase, dry fractionation to remove free fatty acids, and obtain a composition containing 2-glyceryl palmitate after deodorization, and pass GC and thin layer chromatography The conten...

Embodiment 3

[0037] Under the same conditions, the products were prepared respectively according to the preparation method of the present invention and the existing preparation method, and compared.

[0038] The method of the invention

[0039] (1) Provide a kind of shortening, its palmitic acid accounts for 23.0% of total fatty acid ratio, and 2-position palmitic acid content is 16.9%.

[0040] (2) Put 200 g of shortening, 200 g of ethyl palmitate, 20 g of lipase and 1 g of deionized water as the reaction substrates in a container, stir and raise the temperature to 60° C. and keep it constant, and continue the reaction for 8 hours. After the reaction, fatty acid ethyl ester was removed by molecular distillation to obtain oil A.

[0041] (3) Mix 300g of oil A and 600g of arachidonic acid, put it in a container, stir and heat up to 60°C and keep it constant, add 700ml of octane, add 37g of sn-1,3 specific lipase, and maintain the reaction for 8 hours, Mixed oil B is obtained.

[0042] (...

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PUM

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Abstract

The invention relates to a method for preparing a composition containing 2-palmitin. The method comprises the steps of providing a glyceride containing a palmitate residue; mixing the glyceride containing the palmitate residue with palmitic acid, palmitate or palmitic acid non-glyceride, and performing ester exchange to obtain grease A; performing enzymatic directional ester exchange on the grease A and unsaturated fatty acid or non-glyceride of the unsaturated fatty acid to obtain mixed oil B; refining the mixed oil B to obtain the composition containing 2-palmitin. The preparation process is simple. Compared with the existing method, the method disclosed by the invention has the advantages that the content of palmitic acid at the second site in the product prepared by using the method is higher, and fewer byproducts are produced after preparation, so that the method is favorable for environment friendliness.

Description

technical field [0001] The invention relates to a preparation method of a composition containing 2-glyceryl palmitate. Background technique [0002] Triglycerides are the main fat components ingested by humans. Modern nutrition has confirmed that in the process of digesting triglycerides, the human body will preferentially hydrolyze the fatty acids at the Sn-1 and 3 positions to form 2-monoglycerides and a large amount of free fatty acids. These free fatty acids will undergo two reactions in the body: 1. be absorbed by itself; 2. be excreted after reacting with other substances in the body. Studies have shown that compared with free unsaturated fatty acids, free saturated fatty acids have a slower absorption rate and are more likely to react with calcium to form insoluble soap calcium, which is then excreted from the body. It can be seen that compared with triglycerides that produce free saturated fatty acids, triglycerides that produce free unsaturated fatty acids are mor...

Claims

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Application Information

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IPC IPC(8): C12P7/64C11C3/10
CPCC11C3/10C12P7/6445
Inventor 汪志明李翔宇陆姝欢周强汪锋肖敏
Owner CABIO BIOTECH WUHAN CO LTD
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