9results about How to "Increase infection" patented technology

The invention relates to a multi-mode heart and cerebral hemodynamics monitoring method and device, and belongs to the technical field of medical equipment. According to the method, brain absorbance information and pulse wave information at the middle artery of the brain are obtained based on a near infrared spectrum technology by utilizing the relevance among the cardiac output, blood pressure, intracranial pressure and cerebral perfusion pressure of a human body, cardiac output information and cuff-free blood pressure information are obtained based on a thoracic impedance method, and physiological signals are obtained based on the two methods; and carrying out fusion processing to obtain a multi-modal signal, and further constructing a non-invasive monitoring model of non-invasive intracranial pressure, cardiac output, blood pressure and cerebral perfusion pressure, so as to realize continuous non-invasive monitoring reflecting human heart and cerebral hemodynamic parameters. According to the invention, through fusion application of multi-mode signals, the mechanism of cardio-cerebral hemodynamics interaction can be effectively disclosed, and a more effective, safer and noninvasive monitoring means is provided for clinic.

A biocidal product for application to a surface, in particular a porous surface, such as a fabric, textile, and the like, which product incorporates an identification mark that enables the presence of the product to be confirmed and thus protected in maintenance. The biocidal composition comprises: between 0.01% and 0.05%, relative to the total weight of the product, of a vinyl ester resin acting as a carrier for the biocidal agent; the mixture is formed by combining 0.1 to 2.0 percent of dimethyl didecyl ammonium chloride and 2.0 to 10.0 percent of dimethyl octadecyl [3-(trimethoxysilyl) propyl] ammonium chloride in a medium which is formed by a mixture of 0.2 to 1.0 percent of methanol and 0.02 to 1.50 percent of ethanol; urea with a ratio of 0.2 to 1.0% and acetic acid with a ratio of 0.001 to 0.010%; and the luminescent additive is combined with the aluminosilicate metal oxide containing rare earth ions in the form of a dopant.

The utility model discloses an osteomyelitis minimally invasive medullary cavity focus cleaner which comprises a group of screws which are symmetrically arranged, a channel is arranged in the screws in a penetrating mode, a penetrating-in hole and a penetrating-out hole are formed in the two ends of the channel respectively, the penetrating-in hole is formed in the ends, away from the pointed ends, of the screws, the penetrating-out hole is formed in the side walls of the screws, a guide pipe is arranged in the channel in a penetrating mode, and an inner guide pipe is arranged in the guide pipe in a penetrating mode. The channels communicated with the medullary cavity are arranged on the bones on the two sides of the focus respectively, flushing fluid is flushed into one side of the focus along the channels to flush and dilute diseased tissue, and the diseased tissue which falls off due to flushing or is improved in liquidity due to dilution is extracted from the other side of the focus along the channels. Therefore, the aim of cleaning the focus in the medullary cavity is fulfilled. The screw is used for perforating a bone with a medullary cavity focus needing to be removed, the hollow hose type catheter penetrates into the medullary cavity along a channel, the inner catheter made of the flexible material penetrates into the catheter, direct contact and friction between the catheter and medullary are reduced, and reverse transfer and infection expansion of the osteomyelitis focus are avoided.

The invention discloses a pelteobagrus fulvidraco circRNA (Ribonucleic Acid) and application thereof, the circRNA is named as circPIK3C2A, and the nucleotide sequence of the circRNA is shown as SEQ ID NO.1. The pelteobagrus fulvidraco circRNA is named as circPIK3C2A. The circPIK3C2A provided by the invention is highly in positive correlation with the infection duration of aeromonas veronii. After the synthesized circPIK3C2A interferent (si-circPIK3C2A) is transfected to liver cells of the pelteobagrus fulvidraco, the expression of autophagy genes PIK3C2A and DDIT4 can be obviously promoted, the expression of apoptosis genes CASP3 and TRAF2 is inhibited, and the regulation and control effects of the circPIK3C2A on the autophagy, apoptosis and antibacterial processes of the pelteobagrus fulvidraco under bacterial infection are effectively proved.

The present invention relates to the field of biomedicine, and the present invention relates to the use of an RGD peptide in the preparation of drugs for resisting aquatic animal viruses and viral diseases, wherein the RGD peptide is a polypeptide composed of three amino acids, Arg-Gly-Asp. (1) The present invention first verifies from both positive and negative aspects: FN protein can promote GCRV, SVCV and KHV infection after incubation of grass carp kidney cells and carp epithelial cells, and can inhibit the infection of the three viruses after treatment with the FN inhibitor RGD peptide. (2) The present invention reveals a new biological function of the RGD peptide, which can effectively inhibit the invasion of viruses into cells and reduce the infection of viruses in hosts. The present invention also found that at a certain concentration, the RGD peptide is not toxic to grass carp and carp cells. It provides a theoretical and factual basis for the development of drugs for resisting aquatic animal viral diseases.

The invention relates to health-care digestion tea for enhancing immunity and a preparation method of the health-care digestion tea. The preparation method comprises the following steps: S1, picking sour oranges; s2, extruding acid water and small particles; s3, preparing other materials; s4, drying in the sun at low temperature; s5, cutting into small leaf pieces; s6, sterilizing at high temperature; s7, mixing the materials; s8, performing soft twisting; s9, rubbing fragrance; s10, adding honey; s11, drying; and S12, packaging. The health-care digestion tea capable of enhancing immunity contains rich tartaric acid, vitamin C, potassium element and flavonoid compounds, is sour, sweet and fragrant in taste, can be used for treating diseases such as eye diseases, hypertension, asthma, arteriosclerosis and respiratory tract infection after being drunk for a long time, and has the effects of promoting digestion, enhancing immunity, enhancing body resistance, enhancing gastrointestinal motility, promoting digestion and promoting digestion. The health-care tea has the functions of relieving gastrointestinal discomfort, preventing cold, preventing cerebrovascular diseases and the like, helping to resist formation of skin melanin and promoting beauty maintaining and young keeping, and the formula of the health-care tea is specially designed to improve immunity.

This invention belongs to the fields of genetic engineering and fish molecular breeding technology, specifically relating to the application of ARMH3 inhibitors in the preparation of antiviral drugs for fish or the creation of hemorrhagic disease-resistant fish germplasm. This invention discloses that ARMH3 is an important host factor for grass carp reovirus infection. The amino acid sequence of ARMH3 is shown in SEQ ID NO.1. ARMH3 is utilized by grass carp reovirus, promoting viral inclusion body formation, thereby facilitating viral replication and infection. This invention utilizes inhibitors of the ARMH3 protein encoded in grass carp... ARMH3 Genes were edited using CRISPR / Cas9 to create... ARMH3 Knockout chimeric grass carp populations exhibit significant resistance to hemorrhagic disease. This invention provides molecular targets and methods for the rapid creation of new grass carp germplasm resistant to hemorrhagic disease.

The present invention belongs to the technical field of aquaculture and aquatic virus prevention and control, and specifically relates to the application of lactate ions in the preparation of products for preventing and treating carp spring viremia. The present invention finds that the lack of lactate dehydrogenase (LDHA) will lead to a decrease in the resistance of zebrafish to SVCV infection, and then concludes that the supplementation of lactate ions can achieve the effect of preventing and treating carp spring viremia virus (SVCV) infection. Specific lactate ions can effectively enhance the fish body's resistance to SVCV infection, inhibit SVCV replication and proliferation, and increase the survival rate of infected fish bodies, and can be effectively applied to SVCV prevention and treatment in carp fish farming. And the sodium lactate that provides lactate ions is low in price and highly economical.

The utility model belongs to the technical field of postoperative nursing of cleft palate children, and discloses an auxiliary device for cleaning an operation area of the cleft palate children. The device comprises a tongue depressor, one end of the tongue depressor is connected with a handle, the front face of the other end of the tongue depressor is provided with a plane mirror and a lighting device, the back face, opposite to the plane mirror, of the tongue depressor is further provided with a reserved groove, the center of the reserved groove is connected with a connecting rod through a rotating shaft, and the tail end of the connecting rod is connected with a fixing rod in cooperation with a quick connecting mechanism. The other end of the fixing rod is connected to the center of the side face of the occlusal pad. The occlusal pad made of medical silica gel or medical rubber is used for assisting a patient in opening the mouth, the tongue depressor is used for controlling tongue movement of the patient, the lighting device on the tongue depressor is used for enabling an operation area to be clear, the plane mirror on the tongue depressor is used for checking wound healing conditions of the operation area conveniently, and efficient and convenient operation area cleaning and disinfection of a cleft palate child after an operation are achieved. Therefore, infection of an operation area is prevented, wound healing of a patient is promoted, healing time is shortened, and healing effect is improved.