Method for extracting cordycepin

Abstract

The invention relates to a method for extracting cordycepin. The method includes the following steps of subjecting a cordycepin fermentation liquid to reduced pressure concentration, then performing ultrasonic extraction in combinations of microwaves and light waves respectively, and further subjecting an obtained extraction liquid to separation and purification to obtain the cordycepin. Compared with traditional extraction methods, the method has the advantages that by means of the method, the extraction ratio is improved, extraction time is saved, and purity is increased.

Description

technical field

[0001] The invention relates to an extraction method of active ingredients, in particular to an extraction method of cordycepin. Background technique

[0002] Cordycepin (cordycepin) is also known as 3'-deoxyadenosine, Cordyceps, Cordyceps militaris, Cordyceps cephalosporin mycelium, 3-deoxyacyl glycosides, Cordyceps sinensis, Cordyceps sinensis.

[0003] Cordycepin is the main active ingredient in Cordyceps militaris (especially nucleosides), and it is also the first nucleoside antibiotic isolated from fungi.

[0004] Cordycepin (Cordycepin) is an analogue of adenosine, molecular formula: C 10 h 13 N 5 o 3 , Molecular weight: 251.24, basic, needle-like or flaky crystal, melting point 230°C-231°C, maximum absorption wavelength 259.0nm.

[0005] In 1951, Cunningham in Germany isolated and discovered cordycepin from the culture filtrate of Cordyceps militaris.

[0006] Since the 1960s, the synthesis and extraction of cordycepin has attracted widespread at...