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Washing-free antibacterial hand sanitizer and preparation method thereof

An antibacterial hand sanitizer and formulation technology, applied in the direction of antibacterial drugs, antifungal agents, pharmaceutical formulations, etc., can solve the problem of broad-spectrum antibacterial without synergistic antibacterial effect, long-term antibacterial effect, skin without moisturizing and moisturizing, etc. problems, to achieve the effect of low cost, abundant sources and simple equipment

Inactive Publication Date: 2010-07-07
ZHEJIANG KUNZHILIN BIOMEDICINE TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this product has a single disinfection component, only contains chlorhexidine acetate, does not have a synergistic antibacterial effect and a fairly strong broad-spectrum antibacterial and bactericidal effect, and does not have a long-term antibacterial effect; Moisturizing and moisturizing effect

Method used

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  • Washing-free antibacterial hand sanitizer and preparation method thereof
  • Washing-free antibacterial hand sanitizer and preparation method thereof
  • Washing-free antibacterial hand sanitizer and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A kind of disposable antibacterial hand sanitizer, its raw material formula is as follows: 10g of chlorhexidine acetate, 10ug of silver nitrate, 50ml of ethanol, 3g of petrolatum, 1g of stearic acid, 1g of olive oil, 1g of coconut oil, 2g of castor oil, 1g of petrolatum, wool Alcohol 2g, lecithin 1g, lanolin acid 1g, Tween 80 0.5g, glyceryl stearate 1g, PEG-20 sorbitan isostearate 0.5g, carbomer 940 1g, hydroxyethyl cellulose 1 g of hydroxypropyl methylcellulose, 2 g of triethanolamine, 0.5 g of citric acid, 1 g of tartaric acid, 10 ml of glycerin, and 30 ml of deionized water. Configured as 100ml disposable antibacterial hand sanitizer.

[0036] During preparation, Vaseline, stearic acid, olive oil, lecithin, coconut oil, glycerin, castor oil, petrolatum, lanolin alcohol, lanolinic acid and chlorhexidine acetate are added to ethanol, and dissolved at a temperature of 70 degrees to prepare Alcoholic solution; Carbomer 940, hydroxyethylcellulose, hydroxypropylmethylcell...

Embodiment 2

[0038] Chlorhexidine acetate 10g, silver nitrate 100ug, isopropanol 70ml, polysiloxane 7g, cetyl alcohol 2g, petrolatum 3g, sesame oil 1g, almond oil 1g, peanut oil 1g, corn oil 0.5g, rice bran oil 1g, tea Seed oil 0.5g, sea buckthorn oil 1.5g, avocado oil 1g, stone chestnut oil 1g, Tween 801g, macrogol glyceride 1g, glyceryl stearate 0.2g, lecithin 1g, carbomer 940 1g, Carboxymethylcellulose sodium 1g, triethanolamine 2g, glutaric acid 1g, maleic acid 1g, glutamic acid 1g, glycerin 10ml, deionized water 30ml. Configured as 100ml disposable antibacterial hand sanitizer.

[0039] For preparation, polysiloxane, cetyl alcohol, petrolatum, lecithin, sesame oil, almond oil, peanut oil, corn oil, rice bran oil, tea seed oil, sea buckthorn oil, avocado oil, stone chestnut oil, and chlorohexyl acetate Add it to isopropanol, dissolve it at a temperature of 30 degrees, and make an alcohol solution; Carbomer 940, sodium carboxymethylcellulose and Tween 80, macrogol glyceride, glyceryl s...

Embodiment 3

[0041] Chlorhexidine gluconate 5g, silver nitrate 50ug, ethanol 30ml, castor oil 7g, hexadecyl alcohol 2g, petrolatum 3g, polysiloxane 1g, rice bran oil 20g, tea seed oil 10g, seabuckthorn oil 1g, avocado oil 1g , stone chestnut oil 1g, European argan oil 4g, Tween 80 0.2g, glyceryl stearate 0.1, PEG-20 sorbitan isostearate 0.1, lecithin 1g, carbomer 940 1g, methyl Cellulose 1g, sodium carboxymethylcellulose 1g, triethanolamine 2g, malic acid 1g, succinic acid 0.5g, maleic acid 1g, glycerin 10ml, deionized water 50ml. Configured as 100ml disposable antibacterial hand sanitizer.

[0042]For preparation, castor oil, cetyl alcohol, lecithin, petrolatum, silicones, rice bran oil, glycerin, tea seed oil, sea buckthorn oil, avocado oil, stone chestnut oil, argan oil and dextrose chlorhexidine Add salt to ethanol and dissolve at a temperature of 70 degrees to make an alcohol solution; Carbomer 940, methylcellulose, sodium carboxymethylcellulose and Tween 80, glycerol stearate, PEG-2...

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PUM

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Abstract

The invention discloses a washing-free antibacterial hand sanitizer and a preparation method thereof. Raw materials of the washing-free antibacterial hand sanitizer calculated at 100ml include 1-10g of chlorhexidine salt, 5-1,000ug of silver nitrate, 30-90ml of alcohol, 2-50g of skin care agent, 0.5-3g of tackifier, 0.5-3g of surfactant, 0.5-5g of p+H regulator and 15-50ml of deionized water. In the preparation method, the skin care agent and the chlorhexidine salt are added to the alcohol and dissolved under the temperature of 30-70 DEG C to form alcoholic solution; the tackifier, the surfactant and the silver nitrate are added to the deionized water to form aqueous solution; finally, the aqueous solution and the pH regulator are added to the alcoholic solution to prepare the washing-free antibacterial hand sanitizer. The washing-free antibacterial hand sanitizer contains various antibacterial components, has very strong broad-spectrum antibacterial and bactericidal effects on various bacteria and fungi, and has long-acting antibacterial effect.

Description

technical field [0001] The invention relates to a medical antibacterial hand sanitizer, in particular to a disposable antibacterial hand sanitizer with long-lasting antibacterial properties and a preparation method thereof which reduces the resident and transient Staphylococcus aureus, Candida albicans and Escherichia coli on hands. Background technique [0002] The hands of medical staff are an important medium for hospital infection and pathogen transmission. Hand scrubbing and disinfection of surgical personnel before operation plays a vital role in preventing nosocomial infection of surgical patients, as well as the resulting morbidity, death and related costs. There are many types of surgical hand sanitizers, and the composition and content of skin antiseptics vary. Therefore, choosing a suitable disinfectant is the key to the preoperative hand washing and disinfection of surgical personnel. [0003] Among the chemical disinfectants used in hospitals, benzalkonium bro...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/92A61K8/19A61K8/43A61K8/34A61Q19/10A61P31/04A61P31/10
Inventor 魏坤吴远曾晓峰舒丽君
Owner ZHEJIANG KUNZHILIN BIOMEDICINE TECH
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