Anti-inflammatory, antibacterial, itching-relieving and skin-moistening compound composition and preparation method thereof

Abstract

The invention discloses an anti-inflammatory, antibacterial, itching-relieving and skin-moistening compound composition and a preparation method thereof, and relates to the field of medicines. Comprising the following components in parts by weight: 0.5-2 parts of chlorhexidine acetate, 5-15 parts of radix sophorae flavescentis, 2-8 parts of Chinese prickly ash, 3-10 parts of folium artemisiae argyi, 4-12 parts of cortex phellodendri, 2-6 parts of cortex pseudolaricis, 3-9 parts of fructus kochiae, 1-5 parts of cortex dictamni, 1-4 parts of rhizoma atractylodis, 1-4 parts of radix saposhnikoviae, 2-6 parts of fructus cnidii, 1-5 parts of radix cynanchi paniculati, 0.5-2 parts of borneol, 5-15 parts of aloe and 10-30 parts of propylene glycol. 5-15 parts of tea oil and 1-5 parts of herba violae; according to the anti-inflammatory, antibacterial, itching-relieving and skin-moistening compound composition and the preparation method thereof, various Chinese herbal medicine components are carefully screened and scientifically proportioned, so that the compound composition can remarkably inhibit growth of bacteria and fungi and effectively relieve skin inflammation response, and meanwhile, the excellent itching-relieving and skin-moistening effects are shown.

Description

Technical Field

[0001] The invention relates to medical technology, and in particular to an anti-inflammatory, antibacterial, antipruritic and emollient compound composition and a preparation method thereof. Background Art

[0002] With the improvement of people's living standards and the enhancement of health awareness, the demand for skin care and beauty maintenance is also increasing. However, the existing skin care products on the market often have problems such as single efficacy, complex ingredients, and high irritation, which make it difficult to meet the diverse needs of consumers. Especially in the treatment of skin diseases and sensitive skin care, a safe, effective and gentle product is needed to relieve symptoms and improve skin condition.

[0003] Currently, there is a similar anti-inflammatory, antibacterial and antipruritic moisturizing product on the market. Its main ingredients include some common antibacterial agents and chemical synthetic drugs, as well as a small amount of moisturizing ingredients. Most of the existing products contain a variety of chemical synthetic drugs and additives, which may cause certain irritation and allergic reactions to the skin. Although they have certain anti-inflammatory and antibacterial effects, they lack skin care and maintenance functions. Summary of the invention

[0004] The purpose of the present invention is to provide an anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition and a preparation method thereof, so as to solve the above-mentioned deficiencies in the prior art.

[0005] In order to achieve the above-mentioned purpose, the present invention provides the following technical scheme: an anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition, comprising the following ingredients and their weight portions: 0.5-2 parts of chlorhexidine acetate, 5-15 parts of sophora flavescens, 2-8 parts of zanthoxylum bungeanum, 3-10 parts of wormwood, 4-12 parts of phellodendron amurense, 2-6 parts of scutellaria baicalensis bark, 3-9 parts of kochia scoparia, 1-5 parts of white ringworm peel, 1-4 parts of atractylodes, 1-4 parts of siler, 2-6 parts of cnidium monnieri, 1-5 parts of cynanchum wilfordii, 0.5-2 parts of borneol, 5-15 parts of aloe, 10-30 parts of propylene glycol, 5-15 parts of tea oil, 1-5 parts of viola yedoensis and 1-5 parts of lavender essential oil.

[0006] A method for preparing an anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition, which is used to prepare the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition according to claim 1, comprising the following steps:

[0007] a) Grind Sophora flavescens, Zanthoxylum bungeanum, Artemisia argyi, Phellodendron chinense, Rhizoma scopariae, Fructus kochiae, Cortex tinctoriae, Atractylodes macrocephalae, Fructus siler, Fructus cnidii, Fructus cynanchifolia, and Viola yedoensis into fine powder respectively;

[0008] b) stirring the fine powder obtained in step a) with chlorhexidine acetate, borneol, aloe vera, propylene glycol, lavender essential oil, and tea oil until uniformly mixed to obtain a mixture;

[0009] c) adjusting the pH value of the mixture obtained in step c) to an appropriate range;

[0010] d) filling, sealing and sterilizing the pH-adjusted mixture to obtain the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition.

[0011] Furthermore, the grinding process in step a) is carried out under low temperature conditions, and the grinding process adopts ultrafine grinding technology to grind into fine powder of 800-1200 mesh.

[0012] Furthermore, the stirring in step b) until the mixture is uniformly mixed is carried out at a temperature of 60 to 80 degrees Celsius, and the heating and stirring time is 45 to 60 minutes.

[0013] Furthermore, the sterilization treatment in step d) adopts high temperature and high pressure steam sterilization, ultraviolet sterilization or irradiation sterilization.

[0014] Furthermore, when adjusting the pH value of the mixture in step c), one or more pH adjusters are used to adjust the pH value to 5.5 to 6.5.

[0015] Furthermore, an emulsifier is added to the mixture in step b) during stirring.

[0016] Furthermore, natural pigment is added to the mixture in step b) during stirring.

[0017] Furthermore, the filling and sealing in step d) are performed under aseptic conditions.

[0018] Furthermore, before filling and sealing in step d), the method further includes a step of conducting a quality inspection on the mixture, including inspection of appearance, smell, pH value and microbial limit index.

[0019] Compared with the prior art, the present invention provides an anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition and a preparation method thereof. By carefully selecting and scientifically proportioning a variety of Chinese herbal medicine ingredients, the compound composition can significantly inhibit the growth of bacteria and fungi, effectively reduce skin inflammatory reactions, and at the same time exhibit excellent antipruritic and moisturizing effects. This feature makes the composition suitable for the treatment and care of a variety of skin inflammations and itching symptoms, providing patients with a more comprehensive and effective solution.

[0020] During the preparation process, the ultrafine grinding technology under low temperature conditions is used to ensure the effective retention of the active ingredients in the raw materials and avoid high temperature destruction, thereby ensuring the efficacy of the compound composition. At the same time, through fine emulsification, pH adjustment and sterilization treatment, the stability and safety of the product are further improved, ensuring the comfort and peace of mind of patients. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present invention. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0022] Figure 1 The present invention provides an overall structural schematic diagram of the preparation process flow chart of the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition provided in an embodiment of the present invention. DETAILED DESCRIPTION

[0023] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below with reference to the accompanying drawings.

[0024] See also Figure 1 , an anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition, comprising the following ingredients and their weight portions: 0.5-2 parts of chlorhexidine acetate, 5-15 parts of sophora flavescens, 2-8 parts of zanthoxylum bungeanum, 3-10 parts of wormwood, 4-12 parts of phellodendron chinense, 2-6 parts of scutellaria baicalensis bark, 3-9 parts of kochia scoparia, 1-5 parts of white ringworm peel, 1-4 parts of atractylodes, 1-4 parts of siler, 2-6 parts of cnidium monnieri, 1-5 parts of cynanchum wilfordii, 0.5-2 parts of borneol, 5-15 parts of aloe, 10-30 parts of propylene glycol, 5-15 parts of tea oil, 1-5 parts of viola yedoensis and 1-5 parts of lavender essential oil.

[0025] The present invention also discloses a method for preparing an anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition, which specifically comprises the following steps:

[0026] a) grinding Sophora flavescens, Zanthoxylum bungeanum, Artemisia argyi, Phellodendron chinense, Rhizoma truncatum, Fructus kochiae, Cortex tinctorius, Rhizoma atractylodis macrocephalae, Fructus siler, Fructus cnidii, Rhizoma cynanchifoliae, and Herba violaceae into fine powders respectively, and in order to keep the active ingredients in the raw materials from being destroyed by high temperature, thereby ensuring the efficacy of the compound composition, the grinding process is carried out under low temperature conditions, and the grinding process adopts ultrafine grinding technology to grind into fine powder of 800-1200 mesh;

[0027] b) stirring the fine powder obtained in step a) with chlorhexidine acetate, borneol, aloe, propylene glycol, lavender essential oil, and tea oil until uniformly mixed, and further adding an emulsifier and a natural pigment. Adding an emulsifier can help improve the stability and uniformity of the mixture, and further adding a thickener or the like to obtain a compound composition in different forms such as a cream, a gel, or a spray, and adding an appropriate amount of a natural pigment to give the compound composition a desired color. Adding a natural pigment can not only improve the appearance of the product, but also increase the attractiveness of the product, but the amount of the natural pigment added should be controlled within a certain range to avoid affecting the efficacy and stability of the product;

[0028] The stirring process is carried out at a temperature of 60 to 80 degrees Celsius, and the heating and stirring time is 45 to 60 minutes to promote sufficient mixing and dissolution between the raw materials to obtain a mixture;

[0029] c) adjusting the pH value of the mixture obtained in step c) to an appropriate range by using one or more pH adjusters, wherein the pH adjuster may be citric acid, sodium hydroxide, potassium hydroxide, phosphoric acid or phosphate, and the pH value is adjusted to 5.5 to 6.5 to ensure the stability and safety of the product;

[0030] d) filling and sealing the pH-adjusted mixture. Before filling and sealing, the mixture is subjected to quality inspection, including inspection of appearance, odor, pH value and microbial limit index, and sterilization, wherein the sterilization adopts high temperature and high pressure steam sterilization, ultraviolet sterilization or irradiation sterilization, to obtain the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition.

[0031] Chlorhexidine acetate: As a broad-spectrum antibacterial agent, it can effectively inhibit the growth of a variety of bacteria and fungi and reduce the risk of skin infections.

[0032] Sophora flavescens, Zanthoxylum bungeanum, Artemisia argyi, Phellodendron amurense, Rhizoma Cyperi, Kochia scoparia, and Tinea alba: These Chinese herbal ingredients are rich in natural anti-inflammatory and antibacterial ingredients that can work synergistically to reduce skin inflammation and promote skin health.

[0033] Atractylodes, Saposhnikovia divaricata, and Cnidium monnieri: have the effect of dispelling wind and relieving itching, can relieve skin itching symptoms and improve the patient's comfort.

[0034] Xu Changqing: It has the effects of clearing away heat and detoxifying, promoting blood circulation and removing blood stasis. It helps to improve skin blood circulation and promote the repair of damaged skin.

[0035] Borneol: It has the effect of cooling, relieving itching, refreshing the mind, and can quickly relieve skin discomfort.

[0036] Aloe vera: Rich in various nutrients and moisturizing factors, it can moisturize the skin, enhance the skin barrier function, and reduce the damage to the skin caused by external stimuli.

[0037] Propylene glycol and tea oil: As excellent moisturizers and penetrants, they can promote the absorption of active ingredients in the compound composition and improve the therapeutic effect.

[0038] Viola yedoensis: It has the effects of clearing away heat and detoxifying, cooling blood and reducing swelling, and helps to relieve symptoms such as skin redness, swelling and pain.

[0039] By carefully screening and scientifically matching a variety of Chinese herbal ingredients and chemical synthetic ingredients, the compound composition exhibits excellent multiple functions. It can not only significantly inhibit bacterial growth and reduce skin inflammatory reactions, but also has excellent antipruritic and moisturizing effects. It is suitable for the treatment and care of a variety of skin inflammations and itching symptoms. Its preparation method ensures the effective retention and full utilization of the active ingredients in the raw materials. At the same time, through fine emulsification, pH adjustment and sterilization treatment, the stability, safety and comfort of the product are improved. In addition, the compound composition can be made into different forms such as creams, gels or sprays according to needs, which is convenient for patients to choose to use according to actual needs, greatly improving the flexibility and convenience of treatment.

[0040] Embodiment 1:

[0041] The invention discloses an anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition, comprising the following components and their weight portions: 0.5 part of chlorhexidine acetate, 5 parts of sophora flavescens, 2 parts of zanthoxylum bungeanum, 3 parts of wormwood leaf, 4 parts of phellodendron amurense, 2 parts of scutellaria baicalensis bark, 3 parts of kochia scoparia, 1 part of white ringworm peel, 1 part of atractylodes, 1 part of siler, 2 parts of cnidium monnieri, 1 part of cynanchum wilfordii, 0.5 part of borneol, 5 parts of aloe, 10 parts of propylene glycol, 5 parts of tea oil, 1 part of viola yedoensis and 1 part of lavender essential oil.

[0042] The present invention also discloses a method for preparing an anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition, which specifically comprises the following steps:

[0043] a) grinding Sophora flavescens, Zanthoxylum bungeanum, Artemisia argyi, Phellodendron chinense, Rhizoma truncatum, Fructus kochiae, Cortex tinctorius, Rhizoma atractylodis macrocephalae, Fructus siler, Fructus cnidii, Rhizoma cynanchifoliae, and Herba violaceae into fine powders respectively, and in order to keep the active ingredients in the raw materials from being destroyed by high temperature, thereby ensuring the efficacy of the compound composition, the grinding process is carried out under low temperature conditions, and the grinding process adopts ultrafine grinding technology to grind into fine powder of 800-1200 mesh;

[0044] b) stirring the fine powder obtained in step a) with chlorhexidine acetate, borneol, aloe, propylene glycol, lavender essential oil, and tea oil until uniformly mixed, and further adding an emulsifier and a natural pigment. Adding an emulsifier can help improve the stability and uniformity of the mixture, and further adding a thickener or the like to obtain a compound composition in different forms such as a cream, a gel, or a spray, and adding an appropriate amount of a natural pigment to give the compound composition a desired color. Adding a natural pigment can not only improve the appearance of the product, but also increase the attractiveness of the product, but the amount of the natural pigment added should be controlled within a certain range to avoid affecting the efficacy and stability of the product;

[0045] The stirring process is carried out at a temperature of 70 degrees Celsius, and the heating and stirring time is 50 minutes to promote sufficient mixing and dissolution between the raw materials to obtain a mixture;

[0046] c) adjusting the pH value of the mixture obtained in step c) to an appropriate range by using one or more pH adjusters, wherein the pH adjuster may be citric acid, sodium hydroxide, potassium hydroxide, phosphoric acid or phosphate, and the pH value is adjusted to 6 to ensure the stability and safety of the product;

[0047] d) filling and sealing the pH-adjusted mixture. Before filling and sealing, the mixture is subjected to quality inspection, including inspection of appearance, odor, pH value and microbial limit index, and sterilization, wherein the sterilization adopts high temperature and high pressure steam sterilization, ultraviolet sterilization or irradiation sterilization, to obtain the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition.

[0048] Test data:

[0049] Appearance: Milky white paste without obvious particles.

[0050] Smell: Slight herbal scent.

[0051] Microbiological limits: No bacteria, mold or yeast were detected.

[0052] Anti-inflammatory effect: The inhibition rate of mouse skin inflammation model was 85%.

[0053] Antibacterial effect: The diameters of the inhibition zones for Staphylococcus aureus and Escherichia coli are 20 mm and 18 mm respectively.

[0054] Antipruritic effect: The antipruritic rate for the guinea pig skin itching model is 90%.

[0055] Embodiment 2:

[0056] The invention discloses an anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition, comprising the following components and their weight portions: 1 part of chlorhexidine acetate, 10 parts of sophora flavescens, 5 parts of zanthoxylum bungeanum, 6 parts of wormwood leaf, 8 parts of phellodendron amurense, 4 parts of euphorbia pulex, 6 parts of kochia scoparia, 3 parts of white ringworm peel, 2 parts of atractylodes, 2 parts of siler, 4 parts of cnidium monnieri, 3 parts of cynanchum wilfordii, 1 part of borneol, 10 parts of aloe, 20 parts of propylene glycol, 10 parts of tea oil, 3 parts of viola yedoensis and 3 parts of lavender essential oil.

[0057] The present invention also discloses a method for preparing an anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition, which specifically comprises the following steps:

[0058] a) grinding Sophora flavescens, Zanthoxylum bungeanum, Artemisia argyi, Phellodendron chinense, Rhizoma truncatum, Fructus kochiae, Cortex tinctorius, Rhizoma atractylodis macrocephalae, Fructus siler, Fructus cnidii, Rhizoma cynanchifoliae, and Herba violaceae into fine powders respectively, and in order to keep the active ingredients in the raw materials from being destroyed by high temperature, thereby ensuring the efficacy of the compound composition, the grinding process is carried out under low temperature conditions, and the grinding process adopts ultrafine grinding technology to grind into fine powder of 800-1200 mesh;

[0059] b) stirring the fine powder obtained in step a) with chlorhexidine acetate, borneol, aloe, propylene glycol, lavender essential oil, and tea oil until uniformly mixed, and further adding an emulsifier and a natural pigment. Adding an emulsifier can help improve the stability and uniformity of the mixture, and further adding a thickener or the like to obtain a compound composition in different forms such as a cream, a gel, or a spray, and adding an appropriate amount of a natural pigment to give the compound composition a desired color. Adding a natural pigment can not only improve the appearance of the product, but also increase the attractiveness of the product, but the amount of the natural pigment added should be controlled within a certain range to avoid affecting the efficacy and stability of the product;

[0060] The stirring process is carried out at a temperature of 70 degrees Celsius, and the heating and stirring time is 50 minutes to promote sufficient mixing and dissolution between the raw materials to obtain a mixture;

[0061] c) adjusting the pH value of the mixture obtained in step c) to an appropriate range by using one or more pH adjusters, wherein the pH adjuster may be citric acid, sodium hydroxide, potassium hydroxide, phosphoric acid or phosphate, and the pH value is adjusted to 6 to ensure the stability and safety of the product;

[0062] d) filling and sealing the pH-adjusted mixture. Before filling and sealing, the mixture is subjected to quality inspection, including inspection of appearance, odor, pH value and microbial limit index, and sterilization, wherein the sterilization adopts high temperature and high pressure steam sterilization, ultraviolet sterilization or irradiation sterilization, to obtain the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition.

[0063] Test data:

[0064] Appearance: Light yellow paste, without obvious particles.

[0065] Smell: Slight herbal scent.

[0066] Microbiological limits: No bacteria, mold or yeast were detected.

[0067] Anti-inflammatory effect: The inhibition rate of mouse skin inflammation model was 88%.

[0068] Antibacterial effect: The diameters of the inhibition zones for Staphylococcus aureus and Escherichia coli are 22 mm and 20 mm respectively.

[0069] Antipruritic effect: The antipruritic rate for the guinea pig skin itching model is 92%.

[0070] Embodiment three:

[0071] The invention discloses an anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition, comprising the following components and their weight proportions: 2 parts of chlorhexidine acetate, 15 parts of sophora flavescens, 8 parts of zanthoxylum bungeanum, 10 parts of wormwood leaf, 12 parts of phellodendron amurense, 6 parts of euphorbia pulex, 9 parts of kochia scoparia, 5 parts of white ringworm peel, 4 parts of atractylodes, 4 parts of siler, 6 parts of cnidium monnieri, 5 parts of cynanchum wilfordii, 2 parts of borneol, 15 parts of aloe, 30 parts of propylene glycol, 15 parts of tea oil, 5 parts of viola yedoensis and 5 parts of lavender essential oil.

[0072] The present invention also discloses a method for preparing an anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition, which specifically comprises the following steps:

[0073] a) grinding Sophora flavescens, Zanthoxylum bungeanum, Artemisia argyi, Phellodendron chinense, Rhizoma truncatum, Fructus kochiae, Cortex tinctorius, Rhizoma atractylodis macrocephalae, Fructus siler, Fructus cnidii, Rhizoma cynanchifoliae, and Herba violaceae into fine powders respectively, and in order to keep the active ingredients in the raw materials from being destroyed by high temperature, thereby ensuring the efficacy of the compound composition, the grinding process is carried out under low temperature conditions, and the grinding process adopts ultrafine grinding technology to grind into fine powder of 800-1200 mesh;

[0074] b) stirring the fine powder obtained in step a) with chlorhexidine acetate, borneol, aloe, propylene glycol, lavender essential oil, and tea oil until uniformly mixed, and further adding an emulsifier and a natural pigment. Adding an emulsifier can help improve the stability and uniformity of the mixture, and further adding a thickener or the like to obtain a compound composition in different forms such as a cream, a gel, or a spray, and adding an appropriate amount of a natural pigment to give the compound composition a desired color. Adding a natural pigment can not only improve the appearance of the product, but also increase the attractiveness of the product, but the amount of the natural pigment added should be controlled within a certain range to avoid affecting the efficacy and stability of the product;

[0075] The stirring process is carried out at a temperature of 70 degrees Celsius, and the heating and stirring time is 50 minutes to promote sufficient mixing and dissolution between the raw materials to obtain a mixture;

[0076] c) adjusting the pH value of the mixture obtained in step c) to an appropriate range by using one or more pH adjusters, wherein the pH adjuster may be citric acid, sodium hydroxide, potassium hydroxide, phosphoric acid or phosphate, and the pH value is adjusted to 6 to ensure the stability and safety of the product;

[0077] d) filling and sealing the pH-adjusted mixture. Before filling and sealing, the mixture is subjected to quality inspection, including inspection of appearance, odor, pH value and microbial limit index, and sterilization, wherein the sterilization adopts high temperature and high pressure steam sterilization, ultraviolet sterilization or irradiation sterilization, to obtain the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition.

[0078] Test data:

[0079] Appearance: Light yellow paste with a small amount of particles.

[0080] Smell: Slight herbal scent.

[0081] Microbiological limits: No bacteria, mold or yeast were detected.

[0082] Anti-inflammatory effect: The inhibition rate of mouse skin inflammation model was 75%.

[0083] Antibacterial effect: The diameters of the inhibition zones for Staphylococcus aureus and Escherichia coli are 16mm and 15mm respectively.

[0084] Antipruritic effect: The antipruritic rate for the guinea pig skin itching model is 80%.

[0085] Comparative Example:

[0086] We selected an anti-inflammatory, antibacterial and antipruritic moisturizer with relatively high sales volume on the market for testing. The test data are as follows:

[0087] Appearance: There are a few particles.

[0088] Odor: Slight chemical odor.

[0089] Microbiological limit: A small amount of bacteria was detected.

[0090] Anti-inflammatory effect: The inhibition rate of mouse skin inflammation model was 70%.

[0091] Antibacterial effect: The diameters of the inhibition zones for Staphylococcus aureus and Escherichia coli are 15mm and 13mm respectively.

[0092] Antipruritic effect: The antipruritic rate for the guinea pig skin itching model is 80%.

[0093] By comparing with the existing products on the market, it can be seen that the compound compositions of Examples 1, 2 and 3 all show more excellent effects in anti-inflammatory, antibacterial, antipruritic and moisturizing aspects, and the existing products on the market of the comparative examples are lower than those of Examples 1, 2 and 3 in various indicators, indicating that the compound compositions of the present invention have significant advantages.

[0094] In the description of the present invention, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. "Multiple" means two or more, unless otherwise clearly and specifically defined.

[0095] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0096] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.

[0097] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example" or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, unless they are contradictory.

[0098] In the drawings of the embodiments disclosed in the present invention, only the structures related to the embodiments disclosed in the present invention are involved, and other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of the present invention can be combined with each other.

[0099] Although the present invention has been described in detail with reference to the aforementioned embodiments, it is still possible for those skilled in the art to modify the technical solutions described in the aforementioned embodiments, or to make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. An anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition, characterized in that: The invention comprises the following ingredients and their weight proportions: 0.5-2 parts of chlorhexidine acetate, 5-15 parts of sophora flavescens, 2-8 parts of zanthoxylum bungeanum, 3-10 parts of wormwood leaf, 4-12 parts of phellodendron amurense, 2-6 parts of scutellaria baicalensis bark, 3-9 parts of kochia scoparia, 1-5 parts of white ringworm peel, 1-4 parts of atractylodes, 1-4 parts of siler, 2-6 parts of cnidium monnieri, 1-5 parts of cynanchum wilfordii, 0.5-2 parts of borneol, 5-15 parts of aloe, 10-30 parts of propylene glycol, 5-15 parts of tea oil, 1-5 parts of viola yedoensis and 1-5 parts of lavender essential oil.

2. A method for preparing an anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition, which is used to prepare the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition according to claim 1, characterized in that: The following steps are involved: a) Grind Sophora flavescens, Zanthoxylum bungeanum, Artemisia argyi, Phellodendron chinense, Rhizoma scopariae, Fructus kochiae, Cortex tinctoriae, Atractylodes macrocephalae, Fructus siler, Fructus cnidii, Fructus cynanchifolia, and Viola yedoensis into fine powder respectively; b) stirring the fine powder obtained in step a) with chlorhexidine acetate, borneol, aloe vera, propylene glycol, lavender essential oil, and tea oil until uniformly mixed to obtain a mixture; c) adjusting the pH value of the mixture obtained in step c) to an appropriate range; d) filling, sealing and sterilizing the pH-adjusted mixture to obtain the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition.

3. The method for preparing the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition according to claim 2, characterized in that: The grinding process in step a) is carried out under low temperature conditions, and the grinding process adopts ultrafine grinding technology to grind into fine powder of 800-1200 mesh.

4. The method for preparing the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition according to claim 2, characterized in that: The stirring in step b) until the mixture is uniformly mixed is carried out at a temperature of 60 to 80 degrees Celsius, and the heating and stirring time is 45 to 60 minutes.

5. The method for preparing the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition according to claim 2, characterized in that: The sterilization treatment in step d) adopts high temperature and high pressure steam sterilization, ultraviolet sterilization or irradiation sterilization.

6. The method for preparing the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition according to claim 2, characterized in that: When adjusting the pH value of the mixture in step c), one or more pH adjusters are used to adjust the pH value to 5.5 to 6.

5.

7. The method for preparing the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition according to claim 2, characterized in that: The emulsifier is added to the mixture in step b) during stirring.

8. The method for preparing the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition according to claim 2, characterized in that: The natural pigment is added to the mixture in step b) during stirring.

9. The method for preparing the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition according to claim 2, characterized in that: The filling and sealing in step d) are performed under sterile conditions.

10. The method for preparing the anti-inflammatory, antibacterial, antipruritic and moisturizing compound composition according to claim 2, characterized in that: Before filling and sealing in step d), the mixture is also subjected to quality inspection, including inspection of appearance, smell, pH value and microbial limit index.

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