Female genital tract repair gel containing compound enzyme and preparation method thereof

Abstract

The invention provides a female genital tract repair gel containing compound enzyme and a preparation method thereof, and relates to the technical field of gynecological hygiene, the preparation method comprises the following steps: S1, material preparation: uniformly mixing chlorhexidine acetate, carbomer, triethanolamine and glycerol according to parts by mass, and adding antioxidant enzyme and lysozyme solution for dissolution; s2, emulsifying: loading into a vacuum homogeneous emulsifying machine, uniformly stirring, heating to 60-90 DEG C from normal temperature, preserving heat, cooling to normal temperature, heating to 60-90 DEG C from normal temperature for 1-1.5 hours, preserving heat for 1-2 hours, and cooling to normal temperature for 0.5-1 hour; the interior of the gel tube is filled with the glue injection sleeve through pressure pushing, the filling speed is high, filling is compact, a piston in the gel tube is reversely pushed to be outwards pushed to the adaptive height, the glue injection sleeve is automatically in sealed contact with the top end of the gel tube in the filling process, the contact speed is high, contact is tight, and no seepage exists in the filling process.

Description

Technical Field

[0001] The invention relates to the technical field of gynecological hygiene, in particular to a female reproductive tract repair gel containing a composite enzyme and a preparation method thereof. Background Art

[0002] China Science Daily, page 6: Every year, 466,000 women worldwide are diagnosed with cervical cancer, and 132,000 new cases of cervical cancer are reported in my country, accounting for 28% of the world's total number of new cases of cervical cancer, which is six times that of developed countries and is on the rise every year.

[0003] At present, there are also related patent technologies that disclose composite enzyme female reproductive tract repair gel and its preparation method. For example, patent No. CN201810912634.2 discloses a composite enzyme female reproductive tract repair gel and its preparation method, wherein the repair gel comprises the following raw materials in parts by weight: antioxidant enzyme, lysozyme, chlorhexidine acetate, triethanolamine, glycerol, and carbomer. The present invention also provides a preparation method thereof: preparation-emulsification-gelation. The main components of the present invention are antioxidant enzyme, lysozyme, chlorhexidine acetate, etc., pure biological enzyme components, no hormone, no antibiotics, safe ingredients, and no side effects; suitable for daily routine care of women, antibacterial cleaning, deodorization and itching, repair of damage and mucosal barriers; inhibit bacteria and fungi that cause gynecological diseases, and consolidate and improve the resistance of the female reproductive system. It is suitable for a wide range of people, including infants, the elderly, pregnant women, and parturients. The method of use is simple and does not require rinsing.

[0004] Although the above patent discloses a method for preparing a female reproductive tract repair gel containing a composite enzyme, the actual implementation of the preparation of the female reproductive tract repair gel containing a composite enzyme still requires relevant hardware support, and the existing preparation method still has some shortcomings, the specific shortcomings are: Currently, during the storage of the repair gel in the pusher syringe, the repair gel filled into the pusher is easy to leak out from the pusher, resulting in insufficient amount of medicine in the pusher and easily contaminating the surrounding environment where the pusher is placed. Therefore, it is necessary to provide a new method for preparing a female reproductive tract repair gel containing a complex enzyme. Summary of the invention

[0005] In view of the problems in the prior art, the purpose of the present invention is to provide a female reproductive tract repair gel containing a complex enzyme and a preparation method thereof, so as to solve the technical problem described in the above background technology: during the storage of the existing repair gel in the pusher syringe, the repair gel filled into the pusher is easy to leak out of the pusher, resulting in insufficient amount of medicine in the pusher and easy contamination of the surrounding environment where the pusher is placed.

[0006] The technical problem to be solved by the present invention is achieved by adopting the following technical scheme: the female reproductive tract repair gel containing complex enzymes of the present invention comprises the following raw materials: 300u / g-2000u / g of antioxidant enzyme, 1000u / g-5000u / g of lysozyme, chlorhexidine acetate, triethanolamine, glycerol and carbomer.

[0007] The repair gel comprises the following raw materials in parts by mass: 5740-6280 parts by mass of 800u / g antioxidant enzyme, 21500-23560 parts by mass of 3000u / g lysozyme, 3-30 parts by mass of chlorhexidine acetate, 3-300 parts by mass of triethanolamine, 150-1500 parts by mass of glycerol, and 3-900 parts by mass of carbomer.

[0008] The repair gel comprises the following raw materials in parts by mass: 6100 parts by mass of 800u / g antioxidant enzyme, 22950 parts by mass of 3000u / g lysozyme, 12 parts by mass of chlorhexidine acetate, 150 parts by mass of triethanolamine, 600 parts by mass of glycerol, and 150 parts by mass of carbomer. The pH value of the repair gel is 4-8.

[0009] According to the above-mentioned female reproductive tract repair gel containing a composite enzyme, the present invention provides a method for preparing a female reproductive tract repair gel containing a composite enzyme. The method for preparing a female reproductive tract repair gel containing a composite enzyme mainly comprises the following steps: S1. Prepare materials: Evenly mix chlorhexidine acetate, carbomer, triethanolamine and glycerol according to weight proportions, and add antioxidant enzyme and lysozyme solution to dissolve; S2. Emulsification: put into vacuum homogenizer and stir evenly, heat from room temperature to 60-90℃ and keep warm, then cool to room temperature, then heat from room temperature to 60-90℃ for 1-1.5 hours, keep warm for 1-2 hours, and then cool to room temperature for 0.5-1 hour; S3, gelling: the compound enzyme care gel preparation is obtained by standing for 12 hours; the plastic tube is sterilized by high temperature or ultraviolet light to prepare for later filling; S4. Install the gel tube: put the compound enzyme care gel preparation into the gel storage cylinder, use the quantitative pump to intermittently pump the gel preparation, and use the plastic tube to push the gel preparation into each gel tube by pressure quantitative filling. Each gel tube contains 4-5.5g. S5, installing the cover: installing the cover on the top of the gel tube containing the compound enzyme care gel preparation, using the clamping claws on the cover placing assembly to automatically place the cover on the top of each gel tube containing the compound enzyme care gel preparation; S6. Cover pressing: The cover placed on the top of the gel tube is automatically vibrated and pressed by a pressing assembly. The sealing pin at the bottom of the cover is slowly inserted into the needle barrel at the top of the gel tube by high-frequency vibration and the needle barrel at the top of the gel tube is tightened and sealed.

[0010] As a preferred technical solution of the present invention, the above-mentioned steps S5-S6 also include a transmission chain that rotates intermittently in a cycle, wherein sprockets are connected to both ends of the inner ring of the transmission chain, a sprocket shaft is provided in the middle of each sprocket, the bottom of each sprocket shaft is rotatably connected to a base bracket, a fixed leg support is provided at the bottom of the base bracket, the fixed leg is fixed to the ground, a groove wheel is installed at the bottom of each sprocket shaft, a thumbwheel is intermittently meshed and connected to the surface of each groove wheel, each thumbwheel is installed on the output shaft of a servo motor, and the servo motor is fixedly installed on the fixed leg; The surface of the transmission chain is provided with a plurality of equally spaced shipping bases, and two adjacent shipping bases are in close contact with each other. The surface of each shipping base is provided with a hose clamp and a hose bottom support, and the hose bottom support is located below the hose clamp on the surface of the shipping base. A gel tube is installed on the surface of each shipping base, and the gel tube is installed on the hose clamp on the surface of the shipping base. A glue injection component, a cover placement component and a clamping component are sequentially arranged within one cycle of the transmission chain.

[0011] As a preferred technical solution of the present invention, the glue injection assembly includes a glue injection cylinder bracket arranged above the transmission chain, a plurality of glue injection sleeves are arranged at the bottom of the glue injection cylinder bracket, a glue injection pipe joint is arranged at the top of each of the glue injection sleeves, a glue hose groove with a circular hole structure is opened at the bottom of the inner wall of each of the glue injection sleeves, the inner wall diameter of the glue hose groove is slightly larger than the outer wall diameter of the gel tube, a glue spray needle is arranged at the top of the inner wall of the glue hose groove, a glue supply hose is arranged between the top of the glue spray needle and the glue injection pipe joint, an electric push rod 1 is fixed to the bottom of the base bracket, a piston rod 1 is extended upward from the electric push rod 1, and the bottom of the glue injection cylinder bracket is fixed to the top of the piston rod 1.

[0012] As a preferred technical solution of the present invention, a needle tube sealing groove is provided at the top of the inner wall of the hose groove, the needle tube at the top of the gel tube is inserted into the needle tube sealing groove, and a rubber sleeve is fixedly installed on the inner wall surface of the needle tube sealing groove.

[0013] As a preferred technical solution of the present invention, a sealing rubber gasket is fixedly installed on the top of the inner wall of the needle barrel sealing groove, and the sealing rubber gasket is fixed at the top position of the outer cylindrical surface of the glue spray needle.

[0014] As a preferred technical solution of the present invention, an airbag groove is provided on the inner wall of the hose groove, an airbag bag is provided on the inner wall of the airbag groove, an airbag cavity is provided inside the airbag bag, a second air nozzle is provided on the outer wall of the glue injection sleeve, an airway is provided inside the glue injection sleeve, and the airway is connected to the airbag cavity inside the airbag bag.

[0015] As a preferred technical solution of the present invention, the cover placing assembly includes a cover supply channel arranged above the transmission chain, a plurality of flowing covers are arranged at the top of the cover supply channel, a cylinder bracket 1 is arranged at the top of the cover supply channel, a baffle cylinder 1 is fixedly installed at the top of the cylinder bracket 1, a positioning baffle is extended downward from the bottom end of the baffle cylinder 1, and the positioning baffle is arranged at the front end of the cover supply channel.

[0016] As a preferred technical solution of the present invention, the cover placing assembly also includes a lifting frame arranged below the front end of the cover supply channel, the top end of the lifting frame is rotatably connected to a rotating shaft, a rocker arm is arranged in the middle of the rotating shaft, a plurality of clamping claw bases are fixedly installed on the outer wall of the rocker arm, and each of the clamping claw bases has two clamping claws that can clamp each other at the top end, a second pneumatic cylinder is fixedly installed at the bottom of the base bracket, a second pneumatic cylinder extends upwardly with a second piston rod, the lifting frame is fixed to the top end of the second piston rod, a position button is arranged on one side of the lifting frame, a rocker arm pressure rod is arranged on the top end of the rotating shaft on the side of the position button, a second servo motor is fixedly installed on the other side of the lifting frame, and the rotating shaft is driven to rotate by the second servo motor.

[0017] As a preferred technical solution of the present invention, a swing groove is provided at the top of each of the clamping jaw bases, inclined surfaces are provided on both sides of the swing groove, rotating pins are symmetrically provided on the left and right sides of the inner wall of the swing groove, the rotating pin on each side is rotatably connected to the corresponding clamping jaw, a sliding groove is provided at the bottom of the clamping jaw on each side, a bidirectional electric push rod is fixedly installed on the top of the inner wall of the swing groove, reciprocating and telescopic push rods are symmetrically provided on both sides of the bidirectional electric push rod, a sliding pin is provided at the top of the push rod on each side of the electric push rod, and the sliding pin is slidably connected in the sliding groove.

[0018] As a preferred technical solution of the present invention, an electric push rod is arranged in front of the glue injection assembly and in front of the cover placement assembly, a positioning push plate with reciprocating horizontal sliding is arranged behind each of the electric push rods, a hose clamp is arranged at the rear end of each of the positioning push plates, a positioning guard plate 1 is arranged above the shipping base located at the glue injection assembly position, and a positioning guard plate 2 is arranged above the shipping base located at the cover placement assembly position.

[0019] Compared with the prior art, the present invention has the following beneficial effects: 1. The present invention installs a cover on the top of a gel tube containing a compound enzyme care gel preparation, and uses a clamping claw on a cover placement assembly to automatically put the cover on the top of each gel tube containing the compound enzyme care gel preparation; a sealing pin at the bottom of the cover is slowly inserted into the needle tube at the top of the gel tube to tighten and seal the needle tube at the top of the gel tube, thereby effectively preventing the compound enzyme care gel preparation from overflowing from the top of the needle tube of the gel tube, thereby improving the sealing effect of the gel tube.

[0020] 2. The gel tube is transferred to the position of the glue injection component through the shipping base that rotates intermittently in a cycle. The glue injection component is pressed on the top of the gel through the glue injection sleeve, and the female reproductive tract repair gel containing the complex enzyme is filled into the gel tube through the needle tube at the top of the gel tube. The glue injection sleeve uses pressure push to pressure fill the inside of the gel tube. The filling speed is fast and the filling is tight. The piston in the gel tube is pushed outward to the appropriate height in the reverse direction. During the filling process, the glue injection sleeve automatically makes sealing contact with the top of the gel tube with a fast contact speed and tight contact, which can well ensure that the female reproductive tract repair gel containing the complex enzyme can be smoothly injected into the gel tube through the needle tube under pressure push, and there is no seepage during the filling process.

[0021] 3. The present invention provides a hose groove at the bottom of the glue injection sleeve. The gel tube transferred to the glue injection assembly position moves downward through the glue injection sleeve bracket. The downward movement of the glue injection sleeve bracket will drive the hose groove at the bottom of the glue injection sleeve to be stuck on the gel tube on the surface of the shipping base. The hose groove can be easily fitted with the surface of the gel tube by the inner wall diameter being slightly larger than the outer wall diameter of the gel tube. When the needle tube at the top of the gel tube is inserted upward into the needle tube sealing groove, the glue spray needle is inserted from the needle tube at the top of the gel tube into the inside of the gel tube. At this time, the glue injection sleeve bracket is pressed downward to make the needle tube sealing groove The sealing rubber gasket on the top of the wall is tightly pressed against the top of the syringe barrel to achieve pressure sealing. At the same time, the outer wall of the syringe barrel at the top of the gel tube is sealed and wrapped by the flexible and fluffy rubber sleeve on the inner wall of the syringe barrel sealing groove, which effectively reduces the leakage of exudate during the filling process, and can cooperate with the sealing rubber gasket to effectively perform pressure sealing on the syringe barrel at the top of the gel tube. The sealing action is simple, the sealing effect is reliable and it is easy to separate and disassemble, which effectively allows the glue injection sleeve bracket to drop at one time. Several glue injection sleeves at the bottom of the glue injection sleeve bracket can simultaneously perform sealing connection on the syringe barrels at the top of multiple gel tubes.

[0022] 4. The downward movement of the glue injection tube bracket of the present invention will drive the hose groove at the bottom of the glue injection sleeve to be stuck on the gel tube on the surface of the shipping base. The hose groove can be easily fitted with the surface of the gel tube by the inner wall diameter being slightly larger than the outer wall diameter of the gel tube. During the fitting process, the airbag bag of the airbag groove on the inner wall of the hose groove is rapidly expanded, and the top of the gel tube connected to the glue injection sleeve can be wrapped and tightly held, which can effectively prevent the seal of the needle tube from loosening during the process of the glue spray needle pushing the pressure into the gel tube, and effectively prevent the gel tube from being disconnected from the glue injection sleeve. At the same time, the airbag bag has sensitive expansion and contraction reactions, fast movements, and strong wrapping force, and the gel tube is wrapped and bundled to increase the structural strength of the gel tube, effectively preventing the gel tube from bursting during the pressure filling process. The airbag bag has rapid expansion and contraction movements and sensitive reactions, and is very suitable for the frequent and rapid connection and rapid separation requirements of the glue injection sleeve and the top of the gel tube, and effectively improves the filling rate of the gel tube. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] The present invention is further described below in conjunction with the accompanying drawings and embodiments.

[0024] Figure 1 It is a flow chart of the steps of the method for preparing the female reproductive tract repair gel containing complex enzymes of the present invention; Figure 2 It is a schematic diagram of the top view of the transmission chain, the glue injection assembly, the cover placement assembly, and the pressing assembly of the present invention; Figure 3 It is a left-side structural schematic diagram of the glue injection assembly of the present invention; Figure 4 It is a front structural schematic diagram of the glue injection assembly, the cover placement assembly, and the pressing assembly of the present invention; Figure 5 The left side structure diagram of the cover assembly of the present invention is shown in FIG. Figure 1 ; Figure 6 It is a schematic diagram of the cross-sectional structure of the glue injection sleeve of the present invention; Figure 7 This is a schematic cross-sectional structure diagram of the glue injection sleeve of the present invention installed on the top of the gel tube; Figure 8 The present invention is attached to the specification Figure 7 A schematic diagram of the enlarged structure at point A; Fig. 9 The present invention is attached to the specification Figure 7 A schematic diagram of the enlarged structure at B; Fig.10 It is a front cross-sectional structural schematic diagram of the clamping jaws and the clamping cover of the present invention; Fig.11 It is a front cross-sectional structural schematic diagram of the clamping jaws of the present invention when the cover is not clamped; Fig.12It is a schematic diagram of the right side cross-sectional structure of the mud-blocking baffle of the present invention inside the shipping base; Fig.13 A structural comparison diagram of the present invention in which the cover is not installed on the gel tube and the cover is installed on the gel tube; In the figure: sprocket 1, transmission chain 2, gel tube 3, shipping base 4, hose holder 5, glue injection assembly 6, glue injection tube joint 601, glue injection tube bracket 602, second air nozzle 603, glue injection sleeve 604, positioning guard plate 1 605, electric push rod 1 606, mud baffle 607, piston rod 1 608, needle tube sealing groove 609, airway 610, airbag groove 611, airbag bag 612, airbag cavity 613, hose groove 614, rubber sleeve 615, sealing rubber gasket 617, glue supply hose 618, cover placement assembly 7, cover supply flow channel 701, baffle cylinder 1 702, cylinder bracket 1 703, positioning baffle 704, clamping claw 705, claw base 706, swing rod 707, rotating shaft 708, swing arm pressure Rod 709, position button 710, lifting frame 711, piston rod two 712, positioning guard plate two 713, pneumatic cylinder two 714, swing slot 715, two-way electric push rod 716, slide slot 717, sliding pin 718, rotating pin 719, servo motor two 720, clamping assembly 8, clamping frame 801, lifting guide rod 802, tension spring 803, pressing rubber pad 804, vibration base 805, positioning guard plate three 806, pneumatic cylinder three 807, piston rod three 808, vibration wheel 809, positioning push plate 9, electric push rod 10, sprocket shaft 11, groove wheel 12, dial wheel 13, servo motor one 14, fixed support leg 15, base bracket 16, hose bottom support 17, hose clamp 18, roller 19, pushing belt 20. DETAILED DESCRIPTION

[0025] In order to make the technical means, creative features, objectives and effects achieved by the present invention easy to understand, the present invention is further explained below in conjunction with specific diagrams. It should be noted that the embodiments in this application and the features in the embodiments can be combined with each other without conflict.

[0026] Example 1 See also Figure 1 , is a schematic diagram of the overall structure of a female reproductive tract repair gel containing complex enzymes and its preparation method, The repair gel comprises the following raw materials: 300u / g-2000u / g of antioxidant enzyme, 1000u / g-5000u / g of lysozyme, chlorhexidine acetate, triethanolamine, glycerol and carbomer.

[0027] The repair gel comprises the following raw materials in parts by mass: 6000 parts by mass of 800u / g antioxidant enzyme, 22560 parts by mass of 3000u / g lysozyme, 22 parts by mass of chlorhexidine acetate, 200 parts by mass of triethanolamine, 800 parts by mass of glycerol, and 500 parts by mass of carbomer.

[0028] The repair gel comprises the following raw materials in parts by mass: 6100 parts by mass of 800u / g antioxidant enzyme, 22950 parts by mass of 3000u / g lysozyme, 12 parts by mass of chlorhexidine acetate, 150 parts by mass of triethanolamine, 600 parts by mass of glycerol, and 150 parts by mass of carbomer. The pH value of the repair gel is 6.

[0029] According to the above-mentioned female reproductive tract repair gel containing a composite enzyme, the present invention provides a method for preparing a female reproductive tract repair gel containing a composite enzyme. The method for preparing a female reproductive tract repair gel containing a composite enzyme mainly comprises the following steps: S1. Prepare materials: Evenly mix chlorhexidine acetate, carbomer, triethanolamine and glycerol according to weight proportions, and add antioxidant enzyme and lysozyme solution to dissolve; S2, emulsification: put into vacuum homogenizer and stir evenly, heat from room temperature to 90°C and keep warm, then cool to room temperature, then heat from room temperature to 90°C for 1.5 hours, keep warm for 1.5 hours, and then cool to room temperature for 1 hour; S3, gelling: the compound enzyme care gel preparation is obtained by standing for 12 hours; the plastic tube is sterilized by high temperature or ultraviolet light to prepare for later filling; S4, installing gel tubes 3: putting the compound enzyme care gel preparation into the gel storage cylinder, using a quantitative pump to intermittently pump the preparation quantitatively, and then filling the preparation into each gel tube 3 by pressure pushing quantitative filling through a plastic tube, wherein each gel tube contains 5g; S5, installing the cover: installing the cover on the top of the gel tube 3 containing the compound enzyme care gel preparation, using the clamping claw 705 on the cover placing assembly 7 to automatically place the cover on the top of each gel tube 3 containing the compound enzyme care gel preparation; S6. Cover pressing: The cover placed on the top of the gel tube 3 is automatically vibrated and pressed by the pressing assembly 8. The blocking pin at the bottom of the cover is slowly inserted into the needle tube at the top of the gel tube 3 by high-frequency vibration and the needle tube at the top of the gel tube 3 is tightened and sealed.

[0030] The present invention installs a cover on the top of the gel tube 3 containing the complex enzyme care gel preparation, and uses the clamping claws 705 on the cover placement component 7 to automatically put the cover to the top of each gel tube 3 containing the complex enzyme care gel preparation; uses the sealing pin at the bottom of the cover to slowly insert into the needle tube at the top of the gel tube 3 to tighten and seal the needle tube at the top of the gel tube 3, thereby effectively preventing the complex enzyme care gel preparation from overflowing from the top of the needle tube of the gel tube 3, and improving the sealing effect of the gel tube 3.

[0031] The gel tube 3 is placed manually or mechanically on the hose holder 5 and the hose base 17 on the surface of each shipping base 4. The gel tube 3 is transferred to the position of the glue injection component 6 through the cyclic intermittently rotating shipping base 4. The glue injection component 6 is pressed on the top of the gel through the glue injection sleeve 604, and the female reproductive tract repair gel containing the complex enzyme is filled into the gel tube 3 through the needle tube at the top of the gel tube 3. The glue injection sleeve 604 uses pressure pushing to pressure fill the gel tube 3. The filling speed is fast and the filling is tight. The piston in the gel tube 3 is pushed outward to the appropriate height in the reverse direction. During the filling process, the glue injection sleeve 604 automatically makes sealing contact with the top of the gel tube 3 with a fast contact speed and tight contact, which can well ensure that the female reproductive tract repair gel containing the complex enzyme can be smoothly injected into the gel tube 3 through the needle tube under pressure pushing, and there is no seepage during the filling process.

[0032] Example 2 See also Figure 2-Figure 13 This embodiment is similar to the above-mentioned embodiment 1, and the similarities are not described in this embodiment. The specific differences are: The steps S5-S7 described above also include a transmission chain 2 that circulates and intermittently rotates, with sprockets 1 connected to both ends of the inner ring of the transmission chain 2, a sprocket shaft 11 is provided in the middle of each sprocket 1, the bottom of each sprocket shaft 11 is rotatably connected to a base bracket 16, the bottom of the base bracket 16 is provided with a fixed leg 15 for support, the fixed leg 15 is fixed to the ground, a groove wheel 12 is installed at the bottom of each sprocket shaft 11, and a dial wheel 13 is intermittently meshed and connected to the surface of each groove wheel 12, and each dial wheel 13 is installed on the output shaft of a servo motor 14, and the servo motor 14 is fixedly installed on the fixed leg 15; The surface of the transmission chain 2 is provided with a plurality of equally spaced shipping bases 4, and two adjacent shipping bases 4 are in close contact with each other. A hose clamp 5 and a hose bottom support 17 are provided on the surface of each shipping base 4. The hose bottom support 17 is located below the hose clamp 5 on the surface of the shipping base 4. The hose clamp 5 can hold the outer wall of the gel tube tightly, so that the gel tube and the hose clamp 5 are coaxially fixed. A gel tube 3 is installed on the surface of each shipping base 4, and the gel tube 3 is installed on the hose clamp 5 on the surface of the shipping base 4. A glue injection component 6, a cover placement component 7 and a clamping component 8 are sequentially arranged within one cycle of the transmission chain 2. Specifically, the transmission chain 2 is intermittently rotated along the two sprockets 1 in a cycle, so as to realize a continuous supply of gel tubes to the glue injection component, the cover placement component and the clamping component.

[0033] The glue injection assembly 6 includes a glue injection cylinder bracket 602 arranged above the transmission chain 2, and a plurality of glue injection sleeves 604 are arranged at the bottom of the glue injection cylinder bracket 602. A glue injection pipe joint 601 is arranged at the top of each glue injection sleeve 604. The glue injection pipe joint 601 is connected to an external glue supply pump. The glue supply pump is driven by a high-precision metering pump. The metering pump is placed in a gel cylinder for storing repair gel. The metering pump accurately controls the amount of glue sprayed by the glue spray needle 616 inside the glue injection sleeve 604 each time, thereby realizing the filling of a certain amount of repair gel into each gel tube 3. A hose groove 614 with a circular hole structure is provided at the bottom of the inner wall of each glue injection sleeve 604. The inner wall diameter of the hose groove 614 is slightly larger than the outer wall diameter of the gel tube 3. A glue spray needle 616 is provided at the top of the inner wall of the hose groove 614. A glue supply hose 618 is provided between the top of the glue spray needle 616 and the glue injection hose joint 601. An electric push rod 606 is fixed to the bottom of the base bracket 16. A piston rod 608 extends upward from the electric push rod 606. The bottom of the glue injection tube bracket 602 is fixed to the top of the piston rod 608.

[0034] The gel tube 3 is placed manually or mechanically on the hose holder 5 and the hose base 17 on the surface of each shipping base 4. The gel tube 3 is transferred to the position of the glue injection component 6 through the cyclic intermittently rotating shipping base 4. The glue injection component 6 is pressed on the top of the gel through the glue injection sleeve 604, and the female reproductive tract repair gel containing the complex enzyme is filled into the gel tube 3 through the needle tube at the top of the gel tube 3. The glue injection sleeve 604 uses pressure pushing to pressure fill the gel tube 3. The filling speed is fast and the filling is tight. The piston in the gel tube 3 is pushed outward to the appropriate height in the reverse direction. During the filling process, the glue injection sleeve 604 automatically makes sealing contact with the top of the gel tube 3 with a fast contact speed and tight contact, which can well ensure that the female reproductive tract repair gel containing the complex enzyme can be smoothly injected into the gel tube 3 through the needle tube under pressure pushing, and there is no seepage during the filling process.

[0035] A needle tube sealing groove 609 is provided at the top of the inner wall of the hose groove 614, and the needle tube at the top of the gel tube 3 is inserted into the needle tube sealing groove 609. A rubber sleeve 615 is fixedly installed on the inner wall surface of the needle tube sealing groove 609. The rubber sleeve 615 is fixedly installed on the inner wall of the needle tube sealing groove 609 by gluing.

[0036] A sealing rubber gasket 617 is fixedly installed on the top of the inner wall of the needle barrel sealing groove 609 , and the sealing rubber gasket 617 is fixed at the top position of the outer cylindrical surface of the glue spraying needle 616 .

[0037] An airbag groove 611 is provided on the inner wall of the hose groove 614, an airbag bag 612 is provided on the inner wall of the airbag groove 611, an airbag cavity 613 is provided inside the airbag bag 612, a second air nozzle 603 is provided on the outer wall of the glue injection sleeve 604, an airway 610 is provided inside the glue injection sleeve 604, and the airway 610 is connected to the airbag cavity 613 inside the airbag bag 612.

[0038] Specifically, in the present embodiment, the gel tube 3 is placed manually or mechanically on the hose holder 5 and the hose base 17 on the surface of each shipping base 4. The gel tube 3 is transferred to the position of the glue injection component 6 through the shipping base 4 that rotates intermittently in a cycle. The glue injection component 6 is pressed on the top of the gel through the glue injection sleeve 604, and the female reproductive tract repair gel containing the complex enzyme is filled into the gel tube 3 through the needle tube at the top of the gel tube 3. The glue injection sleeve 604 uses pressure pushing to pressure fill the gel tube 3. The filling speed is fast and the filling is tight. The piston in the gel tube 3 is pushed outward to an appropriate height in the reverse direction. During the filling process, the glue injection sleeve 604 automatically makes sealing contact with the top of the gel tube 3 with a fast contact speed and tight contact, which can well ensure that the female reproductive tract repair gel containing the complex enzyme can be smoothly injected into the gel tube 3 through the needle tube under pressure pushing, and there is no seepage during the filling process.

[0039] Specifically, in this embodiment, the present invention provides a hose groove 614 at the bottom of the glue injection sleeve 604, and the gel tube 3 transferred to the position of the glue injection assembly 6 moves downward through the glue injection sleeve bracket 602. The downward movement of the glue injection sleeve bracket 602 will drive the hose groove 614 at the bottom of the glue injection sleeve 604 to be stuck on the gel tube 3 on the surface of the shipping base 4. The hose groove 614 can be easily fitted with the surface of the gel tube 3 by having an inner wall diameter slightly larger than the outer wall diameter of the gel tube 3. During the process of the needle tube at the top of the gel tube 3 being inserted upward into the needle tube sealing groove 609, the glue spray needle is inserted from the needle tube at the top of the gel tube 3 into the inside of the gel tube 3. At this time, the glue injection sleeve bracket 602 is pressed downward. , so that the sealing rubber gasket 617 on the top of the inner wall of the syringe sealing groove 609 is tightly pressed against the top of the syringe to achieve pressure sealing. At the same time, the outer wall of the syringe at the top of the gel tube 3 is sealed and wrapped by the flexible and fluffy rubber sleeve 615 on the inner wall of the syringe sealing groove 609, which effectively reduces the leakage of exudate during the filling process, and can cooperate with the sealing rubber gasket 617 to effectively perform pressure sealing on the syringe at the top of the gel tube 3. The sealing action is simple, the sealing effect is reliable and it is easy to separate and disassemble, which effectively allows the glue injection sleeve 604 bracket to land at one time, and the multiple glue injection sleeves 604 at the bottom of the glue injection sleeve 604 bracket can simultaneously perform sealing connection on the syringes at the top of multiple gel tubes 3.

[0040] Specifically, in this embodiment, the downward movement of the glue injection tube bracket 602 of the present invention will drive the hose groove 614 at the bottom of the glue injection sleeve 604 to be inserted into the gel tube 3 on the surface of the shipping base 4. The hose groove 614 can be easily fitted with the surface of the gel tube 3 by having an inner wall diameter slightly larger than the outer wall diameter of the gel tube 3. During the fitting process, the airbag 612 of the airbag groove 611 on the inner wall of the hose groove 614 is rapidly expanded, which can wrap and hold the top of the gel tube 3 connected to the glue injection sleeve 604, and can effectively prevent the glue spray needle from applying pressure to the inside of the gel tube 3. During the pushing process, the seal of the needle tube is prevented from loosening, and the gel tube 3 is effectively prevented from being disconnected from the glue injection sleeve 604. At the same time, the air bag 612 is sensitive to expansion and contraction, quick to move, and has a strong wrapping force. The gel tube 3 is wrapped and bundled to increase the structural strength of the gel tube 3, and the gel tube 3 is effectively prevented from bursting during the pressure filling process. The air bag 612 expands and contracts quickly and reacts sensitively, which is very suitable for the frequent and rapid connection and rapid separation requirements of the glue injection sleeve 604 and the top of the gel tube 3, and effectively improves the filling rate of the gel tube 3.

[0041] The cover placing assembly 7 includes a cover supply channel 701 arranged above the transmission chain 2, a plurality of flowing covers are arranged at the top of the cover supply channel 701, a cylinder bracket 703 is arranged at the top of the cover supply channel 701, a baffle cylinder 702 is fixedly installed at the top of the cylinder bracket 703, a positioning baffle 704 is extended downward from the bottom end of the baffle cylinder 702, and the positioning baffle 704 is arranged at the front end of the cover supply channel 701.

[0042] The caps in the cap supply channel 701 are placed manually or automatically to achieve continuous supply, and the caps are transported forward by the arc slope of the cap supply channel surface. Specifically, the cap supply channel is not described in detail in this embodiment, and any cap supply channel in the prior art that can achieve the technical effect described in this application can be used as a replacement for the cap supply channel of the present invention.

[0043] The cap placing assembly 7 further includes a lifting frame 711 arranged below the front end of the cap supply channel 701, the top of the lifting frame 711 is rotatably connected to a rotating shaft 708, a swing rod 707 is arranged in the middle of the rotating shaft 708, a plurality of clamping claw bases 706 are fixedly installed on the outer wall of the swing rod 707, and each clamping claw base 706 is provided with two mutually clamping clamping claws 705 at the top, and a pneumatic cylinder 2 714 is fixedly installed at the bottom of the base bracket 16, and the pneumatic cylinder 2 714 extends upward. A piston rod 2 712 is provided, and a lifting frame 711 is fixed to the top of the piston rod 2 712. A position button 710 is provided on one side of the lifting frame 711. A swing arm pressure rod 709 is provided on the top of the rotating shaft 708 on the side of the position button 710. A servo motor 2 720 is fixedly installed on the other side of the lifting frame 711. One end of the rotating shaft 708 is fixedly connected to the output shaft of the servo motor 2 720, and the rotating shaft 708 is driven to rotate by the servo motor 2 720.

[0044] The present invention sets a lifting frame 711 under the front end of the cover supply channel 701. The lifting frame 711 can be lifted and lowered reciprocatingly. At the same time, each cover is put on the top of the corresponding gel tube 3 through the reciprocating swing of the clamping claw base 706. Specifically, when the clamping claw base 706 swings to an upright state, the two clamping claws 705 at the top of the clamping claw base 706 are respectively located on both sides of the flow channel of the cover supply channel 701. When the cover in the cover supply channel 701 extends out and abuts against the surface of the positioning baffle 704, the surface of the positioning baffle 704 is provided with a pressure sensor. When the positioning baffle 704 is quickly lifted up by the baffle cylinder 1 702, the clamping claw 705 quickly clamps the surface of the extended cover. When the positioning baffle 704 is extended upward to the maximum position, the servo motor 2 720 drives the swing rod 707 to swing. During the swing of the swing rod 707, the clamping claw base 706 and the clamping claw 705 are driven to swing to a horizontal state. The clamping claw 705 drives the cover supply channel 701 to move upward. The cover extending from the flow channel 701 rotates to an inverted state. At the same time, the position button 710 is pressed by the swing arm pressure rod 709 during the swinging of the swing rod 707. The pneumatic cylinder 2 714 will push the lifting frame 711 to descend downward. During the downward descent of the lifting frame 711, the cover in the inverted state is inserted into the top of the gel tube 3 below. The clamping claw 705 is released. When the lifting frame 711 descends to the preset lowest position, the cover is just installed on the top of the gel tube 3. When the lifting frame 711 descends to the preset lowest position and starts to return upward, the positioning baffle 704 descends downward, the clamp base 706 and the clamping claw 705 swing to an upright state along the swing rod 707, and the clamping claw 705 is lifted upward to the bottom of the cover supply flow channel 701 through the lifting frame 711. At this time, the cover in the cover supply flow channel 701 extends outward and rests on the surface of the positioning baffle 704. The above steps are repeated continuously to achieve the cover being inserted into different gel tubes 3 in sequence.

[0045] A swinging groove 715 is provided at the top of each clamping jaw base 706, and inclined surfaces are provided on both sides of the swinging groove 715. Rotating pins 719 are symmetrically provided on the left and right sides of the inner wall of the swinging groove 715. The rotating pin 719 on each side is rotatably connected to the corresponding clamping jaw 705. A sliding groove 717 is provided at the bottom of the clamping jaw 705 on each side. A two-way electric push rod 716 is fixedly installed on the top of the inner wall of the swinging groove 715. Reciprocating and telescopic push rods are symmetrically provided on both sides of the two-way electric push rod 716. A sliding pin 718 is provided at the top of the push rod on each side of the two-way electric push rod 716. The sliding pin 718 is slidably connected in the sliding groove 717, so that the two-way electric push rod 716 can push the clamping jaw 705 in both directions to clamp in the same direction, thereby effectively realizing the synchronous clamping of the two clamping jaws 705 at the top of the clamping jaw base 706 and improving the clamping force.

[0046] An electric push rod 10 is provided in front of the glue injection component 6 and the cover placement component 7, and a positioning push plate 9 with reciprocating horizontal sliding is provided behind each electric push rod 10. A hose clamp 18 is provided at the rear end of each positioning push plate 9. A positioning guard plate 1 605 is provided above the shipping base 4 located at the position of the glue injection component 6, and a positioning guard plate 2 713 is provided above the shipping base 4 located at the position of the cover placement component 7.

[0047] The present invention provides an electric push rod 606 in front of the glue injection component 6, and the electric push rod 606 pushes the positioning push plate to slide back and forth horizontally. A positioning guard plate 605 is provided above the shipping base 4 at the position of the glue injection component 6, and the positioning guard plate 605 is used to position the top of each gel tube 3. The gel tube 3 moved to the position of the glue injection component 6 is pushed to be close to the surface of the positioning guard plate 605 by the pushing of the positioning push plate, so as to prevent the gel tube 3 from being skewed, and effectively improve the accuracy of the process of the bottom of the glue injection sleeve 604 being downwardly connected with the top of the gel tube 3. At the same time, the middle part of the gel tube 3 is clamped by the positioning push plate and the positioning guard plate 605, so as to effectively prevent the gel tube 3 from bursting during the pressure filling process, and improve the structural strength of the gel tube 3.

[0048] Specifically, in this embodiment, please refer to the attached manual Fig.12 , a mud-blocking baffle 607 is provided at the bottom of each shipping base 4. The mud-blocking baffle 607 is slidably connected to the inside of the shipping base 4, and an oil cavity is provided inside the shipping base 4. The top of the mud-blocking baffle 607 extends into the oil cavity and is provided at the bottom of the injection assembly 6 through the shipping base 4. When the female reproductive tract repair gel containing the complex enzyme is pushed into the gel tube 3 by pressure, the damping pressure of the mud-blocking baffle 607 makes the piston inside the gel tube 3 have a slight damping pressure, so that the piston rod at the bottom of the gel tube 3 can have a certain pressing force, thereby effectively making the gel tube 3 can be canned more tightly.

[0049] At the same time, a circulating pushing belt 20 is arranged on the left side of the glue injection component 6 and below the transmission chain 2. Rollers 19 are arranged at both ends of the inner circle of the pushing belt 20. The rollers 19 are rotatably connected to the base bracket 16. The inclined setting of the pushing belt 20 can make the gel tube piston rod that has just entered the position of the glue injection component 6 be pushed upward to the topmost position of the gel tube through the pushing belt 20.

[0050] The clamping assembly 8 includes a clamping frame 801 arranged above the transmission chain 2, a pneumatic cylinder 3 807 is fixedly installed at the bottom of the base bracket 16, and a piston rod 3 808 extends upward from the pneumatic cylinder 3 807. The clamping frame 801 is fixed to the top of the piston rod 3 808. A vibration base 805 is arranged at the bottom of each clamping frame 801, and a plurality of pressing rubber pads 804 are arranged at the bottom of the vibration base 805. Each pressing rubber pad 804 is a cylindrical structure. The vibration base 805 A lifting guide rod 802 is fixed to the top of the pressing frame 801 and is upright on the top of the vibration base 805. A symmetrical through-hole is opened on the inner wall surface of the pressing frame 801. The lifting guide rod 802 passes through the round hole on the surface of the pressing frame 801 and extends to the top of the pressing frame 801. A high-speed motor is fixed to the bottom of the pressing frame 801. A vibration wheel 809 is installed on the high-speed motor at the bottom of the pressing frame 801. A tension spring 803 is arranged between the bottom end of the pressing frame 801 and the top of the vibration base 805. Specifically in this embodiment, when the cover is inserted into the top of the gel tube 3 below, the pressing component 8 The high-speed motor on the device drives the vibration wheel 809 to rotate, thereby automatically vibrating and pressing the cover placed on the top of the gel tube 3. The sealing pin at the bottom of the cover is slowly inserted into the needle tube at the top of the gel tube 3 by high-frequency vibration and tightens and seals the needle tube at the top of the gel tube 3.

[0051] The basic principles, main features and advantages of the present invention are shown and described above. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The above embodiments and the description in the specification are only to illustrate the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A method for preparing a female reproductive tract repair gel containing a composite enzyme, characterized in that: The preparation method of the female reproductive tract repair gel containing complex enzymes mainly comprises the following steps: S1. Prepare materials: Evenly mix chlorhexidine acetate, carbomer, triethanolamine and glycerol according to weight proportions, and add antioxidant enzyme and lysozyme solution to dissolve; S2. Emulsification: put into vacuum homogenizer and stir evenly, heat from room temperature to 60-90℃ and keep warm, then cool to room temperature, then heat from room temperature to 60-90℃ for 1-1.5 hours, keep warm for 1-2 hours, and then cool to room temperature for 0.5-1 hour; S3, gelling: the compound enzyme care gel preparation is obtained by standing for 12 hours; the plastic tube is sterilized by high temperature or ultraviolet light to prepare for later filling; S4. Install the gel tube: put the compound enzyme care gel preparation into the gel storage cylinder, use the quantitative pump to intermittently pump the gel preparation, and use the plastic tube to push the gel preparation into each gel tube by pressure quantitative filling. Each gel tube contains 4-5.5g. S5, installing the cover: installing the cover on the top of the gel tube containing the compound enzyme care gel preparation, using the clamping claws on the cover placing assembly to automatically place the cover on the top of each gel tube containing the compound enzyme care gel preparation; S6. Cover pressing: The cover placed on the top of the gel tube is automatically vibrated and pressed by a pressing assembly. The sealing pin at the bottom of the cover is slowly inserted into the needle barrel at the top of the gel tube by high-frequency vibration and the needle barrel at the top of the gel tube is tightened and sealed.

2. The method for preparing a female reproductive tract repair gel containing a composite enzyme according to claim 1, characterized in that: The steps S5-S6 described above also include a transmission chain that circulates and intermittently rotates, wherein the two ends of the inner ring of the transmission chain are respectively connected to sprockets, a sprocket shaft is provided in the middle of each of the sprockets, the bottom of each of the sprocket shafts is rotatably connected to a base bracket, a fixed leg support is provided at the bottom of the base bracket, the fixed leg is fixed to the ground, a groove wheel is installed at the bottom of each of the sprocket shafts, a thumbwheel is intermittently meshed and connected on the surface of each of the groove wheels, each thumbwheel is installed on the output shaft of a servo motor, and the servo motor is fixedly installed on the fixed leg; The surface of the transmission chain is provided with a plurality of equally spaced shipping bases, and two adjacent shipping bases are in close contact with each other. The surface of each shipping base is provided with a hose clamp and a hose bottom support, and the hose bottom support is located below the hose clamp on the surface of the shipping base. A gel tube is installed on the surface of each shipping base, and the gel tube is installed on the hose clamp on the surface of the shipping base. A glue injection component, a cover placement component and a clamping component are sequentially arranged within one cycle of the transmission chain.

3. The method for preparing a female reproductive tract repair gel containing complex enzymes according to claim 2, characterized in that: The glue injection assembly includes a glue injection cylinder bracket arranged above the transmission chain, a plurality of glue injection sleeves are arranged at the bottom of the glue injection cylinder bracket, a glue injection pipe joint is arranged at the top of each of the glue injection sleeves, a hose groove with a circular hole structure is opened at the bottom of the inner wall of each of the glue injection sleeves, the inner wall diameter of the hose groove is slightly larger than the outer wall diameter of the gel tube, a glue spray needle is arranged at the top of the inner wall of the hose groove, a glue supply hose is arranged between the top of the glue spray needle and the glue injection pipe joint, an electric push rod 1 is fixed to the bottom of the base bracket, a piston rod 1 is extended upward from the electric push rod 1, and the bottom of the glue injection cylinder bracket is fixed to the top of the piston rod 1.

4. The method for preparing a female reproductive tract repair gel containing complex enzymes according to claim 3, characterized in that: The top of the inner wall of the rubber tube groove is provided with a needle tube sealing groove, the needle tube at the top of the gel tube is inserted into the needle tube sealing groove, and a rubber sleeve is fixedly installed on the inner wall surface of the needle tube sealing groove.

5. The method for preparing a female reproductive tract repair gel containing complex enzymes according to claim 4, characterized in that: A sealing rubber gasket is fixedly installed on the top of the inner wall of the needle barrel sealing groove, and the sealing rubber gasket is fixed at the top position of the outer cylindrical surface of the glue spraying needle.

6. The method for preparing a female reproductive tract repair gel containing complex enzymes according to claim 5, characterized in that: An airbag groove is provided on the inner wall of the hose groove, an airbag bag is provided on the inner wall of the airbag groove, an airbag cavity is provided inside the airbag bag, a second air nozzle is provided on the outer wall of the glue injection sleeve, an airway is provided inside the glue injection sleeve, and the airway is connected to the airbag cavity inside the airbag bag.

7. The method for preparing a female reproductive tract repair gel containing complex enzymes according to claim 2, characterized in that: The cover placing assembly includes a cover supply channel arranged above the transmission chain, a plurality of flowing covers are arranged at the top of the cover supply channel, a cylinder bracket 1 is arranged at the top of the cover supply channel, a baffle cylinder 1 is fixedly installed at the top of the cylinder bracket 1, a positioning baffle is extended downward from the bottom end of the baffle cylinder 1, and the positioning baffle is arranged at the front end of the cover supply channel.

8. The method for preparing a female reproductive tract repair gel containing complex enzymes according to claim 7, characterized in that: The cover placing assembly also includes a lifting frame arranged below the front end of the cover supply channel, the top end of the lifting frame is rotatably connected to the rotating shaft, the middle part of the rotating shaft is provided with a rocker arm, the outer wall of the rocker arm is fixedly installed with a plurality of clamping claw bases, the top end of each of the clamping claw bases is provided with two clamping claws that can clamp each other, the bottom of the base bracket is fixedly installed with a second pneumatic cylinder, the second pneumatic cylinder extends upward with a second piston rod, the lifting frame is fixed to the top end of the second piston rod, one side of the lifting frame is provided with a position button, the top end of the rotating shaft located on the side of the position button is provided with a rocker arm pressure rod, the other side of the lifting frame is fixedly installed with a second servo motor, and the rotating shaft is driven to rotate by the second servo motor.

9. The method for preparing a female reproductive tract repair gel containing complex enzymes according to claim 8, characterized in that: A swing groove is provided at the top of each clamping jaw base, and inclined surfaces are provided on both sides of the swing groove. Rotating pins are symmetrically provided on the left and right sides of the inner wall of the swing groove. The rotating pin on each side is rotatably connected with the corresponding clamping jaw, and a sliding groove is provided at the bottom of the clamping jaw on each side. A bidirectional electric push rod is fixedly installed on the top of the inner wall of the swing groove, and reciprocating and telescopic push rods are symmetrically provided on both sides of the bidirectional electric push rod. A sliding pin is provided at the top of the push rod on each side of the electric push rod, and the sliding pin is slidably connected in the sliding groove.

10. The method for preparing a female reproductive tract repair gel containing complex enzymes according to claim 2, characterized in that: An electric push rod is arranged in front of the glue injection component and the cover placement component, a positioning push plate with reciprocating horizontal sliding is arranged behind each of the electric push rods, a hose clamp is arranged at the rear end of each of the positioning push plates, a positioning guard plate 1 is arranged above the shipping base located at the glue injection component position, and a positioning guard plate 2 is arranged above the shipping base located at the cover placement component position.

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