55results about How to "Security advantage" patented technology

The invention relates to an inhibitor containing cyclopentane derivatives as well as a preparation method and application of the inhibitor. Particularly, the invention relates to a compound shown in a general formula (I), a preparation method of the compound, a pharmaceutical composition containing the compound and application of the compound as an inhibitor in treatment of cardiovascular diseases, cerebrovascular diseases and other diseases, and substituents in the general formula (I) are as defined in the specification. # imgabs0 #

The invention discloses a method for constructing recombinant hansenula polymorpha for efficiently producing canine serum albumin and an expression method of the recombinant hansenula polymorpha. Based on a natural sequence of a canine serum albumin gene, a codon of the canine serum albumin gene is optimized, so that the canine serum albumin gene is more suitable for being expressed in hansenula polymorpha, an optimal promoter of the sequence expressed in hansenula polymorpha is further screened, and the copy number of the canine serum albumin in hansenula polymorpha is optimized. The yield of the canine serum albumin hansenula polymorpha strain obtained by recombinant transformation can reach 0.8-0.9 g / L after 6 days of high-density fermentation production in a fermentation tank.

The invention belongs to the field of quantum cryptography, and relates to a quantum secret sharing method based on lattice cryptography and random base, comprising the following steps: a secret distributor generates a public key, a private key share and a verification key through a key generation algorithm; encrypting the secret by using the public key to generate a ciphertext; broadcasting the ciphertext to all participants and a secret reconstructor; each participant performs partial decryption on the ciphertext and calculates a shadow corresponding to a decryption value; embedding the shadow and the random number into information particles by adopting unitary operation; a secret restorer calculates the sum of all shadows by measuring the extracted information particles, and removes noise items to obtain a restored secret; verifying whether the recovered secret is correct or not by adopting a hash function; when the participant changes, the secret distributor executes key retransmission, generates a new private key share by re-segmenting elements in the private key vector, and re-distributes the new private key share to the participant; according to the invention, the resource consumption and communication consumption of the scheme are effectively reduced, and the overall efficiency is improved.

The invention relates to the technical field of capacitor electrode material preparation, in particular to a sulfur-doped nickel-manganese layered double hydroxide electrode material, a preparation method and a capacitor, and the preparation method comprises the following steps: growing sulfur-doped nickel-manganese layered double hydroxide on foamed nickel by using a simple and feasible one-step hydrothermal method; oxygen vacancies are introduced into the electrode material through a safe and harmless chemical reduction method; wherein the layered double hydroxide has a relatively large specific surface area and rich active sites, so that permeation of electrolyte and diffusion of ions are facilitated; through combination of sulfur doping and oxygen vacancy, the electronic structure of the electrode material can be synergistically optimized, and the electrolyte adsorption capacity and the electronic conductivity of the electrode material are enhanced. The problems that in the prior art, due to the fact that transition metal layered double hydroxides are low in electric conductivity and poor in electron transmission efficiency, actual energy density and power density are low, and cycling stability is poor are solved.

The invention provides a trusted online and offline federated learning method and system based on Shamir secret sharing, and relates to the technical field of distributed computing and cryptography. The method comprises the following steps: a secret key generation center distributes a secret key for a newly registered user; the model requester determines a threshold value according to a task demand, selects a secret value, performs secret segmentation according to the total number of pre-distributed data providers, and transmits a secret share to the server; the data provider trains a local model by using local data, encrypts the local model by using a public key of a model requester, and sends a ciphertext parameter to the server; the server performs secret recovery on the secret share; if the number of the obtained secret shares exceeds the threshold value requirement, the secret is recovered successfully, and model parameters are aggregated and sent to a model requester; otherwise, the server continues to wait until the number of the obtained secret shares reaches the threshold value requirement. The method has remarkable advantages in the aspects of data privacy, model security and calculation complexity.

The utility model discloses a waste photovoltaic panel glass dismantling device which comprises a working table and supporting legs arranged at the four corners of the lower side of the working table, a conveying belt is arranged in the middle of the upper side of the working table, sliding rails are arranged in the two sides of the middle of the working table respectively, and the sliding rails are arranged in the middle of the working table. Connecting blocks are arranged on the inner sides of the sliding rails, a device frame is arranged in the middles of the upper sides of the two connecting blocks, fixing plates are arranged on the outer portions of the left side and the right side of the device frame correspondingly, spring sleeve rods are arranged on the lower sides of the fixing plates, and pressing rods are arranged on the lower sides of the spring sleeve rods. By means of the arrangement of the abutting block and the sliding groove, the photovoltaic panel can move towards the right side more stably after being cut, fragmentation is prevented, smooth proceeding of the disassembling process is guaranteed, the laser heater is used for replacing a traditional heat conduction oil heating plate, the photovoltaic panel can be heated more efficiently, the disassembling efficiency is improved, and time and energy cost are saved.

The invention relates to the technical field of microorganisms, in particular to monascus for high-yield production of monascus and / or monascus flavin and application of the monascus, a new monascus strain with the preservation number of CGMCC NO.41335 and application of the new monascus strain in production of high-content monascus and / or monascus flavin and related products thereof. The strain is monascus purpureus ZYXQ-2206, can produce high-efficiency and non-toxic monascus and / or monascus flavin at high yield, and does not produce harmful and toxic components such as lovastatin and citrinin. Therefore, a monascus product produced by using the strain can effectively avoid safety risks, and has extremely high application prospects and market potential. By screening and optimizing a fermentation process, the invention provides the high-yield, non-toxic and high-functionality red yeast rice, and the red yeast rice has important application value in the field of development of lipid-lowering functional foods and nutritional health-care products.

The invention discloses a gas-liquid mixing device for a nuclear power station. The gas-liquid mixing device comprises a liquid inlet pipeline, a gas inlet pipeline, a fluid mixing pipeline and a fluid output pipeline, the gas inlet pipeline is communicated with the liquid inlet pipeline, and the liquid inlet pipeline, the fluid mixing pipeline and the fluid output pipeline are sequentially communicated; gas or a gas-liquid mixture is introduced into the gas inlet pipeline; a plurality of mixing elements arranged in the axial direction of the fluid mixing pipeline are arranged in the fluid mixing pipeline and comprise at least one first mixing element and at least one second mixing element, and flow channels of the first mixing elements and flow channels of the second mixing elements are arranged in a staggered mode. Bubble breaking and gas-liquid mixing are carried out through the first mixing element and the second mixing element which are arranged in the fluid mixing pipeline in a staggered mode, gas-liquid sufficient contact mixing is achieved, gas (such as hydrogen) dissolution is promoted, and therefore the concentration of dissolved hydrogen in a primary loop coolant can be maintained or increased.

The invention discloses recombinant hansenula polymorpha for efficiently producing cat serum albumin and an expression method of the recombinant hansenula polymorpha. According to the method, an expression cassette of the cat serum albumin is integrated in hansenula polymorpha, and a promoter in hansenula polymorpha is optimized, so that the serum albumin is expressed by a constitutive promoter and a sucrose inducible promoter independently or in a combined manner, and the copy number of the serum albumin is further optimized; the stable and efficient expression of the cat serum albumin gene in hansenula polymorpha is successfully realized. The high-density fermentation yield of the recombinant cat serum albumin fermented by using the engineering bacteria can reach 1.7-2.2 g / L.

The invention belongs to the technical field of microorganisms, and relates to a bifidobacterium breve strain capable of relieving constipation, the strain is bifidobacterium breve Bb-PG-14, the classification name of the strain is Bifidobacterium breve, the preservation number is CGMCC No.31861, the preservation time is September 4, 2024, the preservation unit is China General Microbiological Culture Collection Center, the preservation number is CGMCC No.31861, the preservation number is CGMCC No.31861, the preservation number is CGMCC No.31861, the preservation number is CGMCC No.31861, the preservation number is CGMCC No.31861, and the preservation number is CGMCC No.31861. The address is No.3, Yard 1, Beichen West Road, Chaoyang District, Beijing. The strain is separated and purified from excrement of healthy babies, has relatively strong acid resistance, alkali resistance, cholate resistance and artificial simulated gastrointestinal fluid tolerance, and has the characteristics of probiotics.

The invention provides a bacterial cellulose-based composite nano-emulsion and a preparation method and application thereof, and relates to the technical field of nano-emulsions.The preparation method comprises the steps that S1, Sanzan gum is dissolved in water, a completely hydrated Sanzan gum solution is prepared, and the mass concentration of Sanzan gum in the Sanzan gum solution is 0.1%-0.3%; s2, the bacterial cellulose suspension is added into the Sanzan gum solution, the mass concentration of bacterial cellulose in the final composite suspension reaches 0.1%-0.5%, and the bacterial cellulose is nano bacterial cellulose; and S3, mixing the composite suspension and an oil phase according to a ratio of 9: 1, and homogenizing to obtain the bacterial cellulose-based composite nano-emulsion. The nano-emulsion is high in biological safety, environmentally friendly, degradable, capable of being prepared at low cost, high in emulsion stability and capable of being stored for a long time.

The utility model discloses grease fitting drilling equipment which comprises a base table, a rotating table, a rotating disc, a grease fitting clamping piece, a supporting plate, a lifting sliding guide rail and a drilling machine, the rotating table is fixedly connected to the upper end of the base table, a rotating motor is fixedly connected to the middle of the rotating table in an embedded mode, and the rotating disc is fixedly connected to the tail end of a rotating shaft of the rotating motor. The rotating table is fixedly connected to the base table, the rotating disc is rotationally connected to the upper end of the rotating table, a plurality of grease fitting clamping pieces are fixedly connected to the upper end of the rotating disc and evenly distributed in an annular array, a supporting plate is fixedly connected to the portion, on one side of the rotating table, of the base table, and a lifting sliding guide rail is fixedly connected to one side of the supporting plate; a drilling machine is fixedly connected to a sliding block of the lifting sliding guide rail. The grease nipple drilling equipment is high in machining efficiency, reduces manual operation, improves production efficiency and is good in stability.

The invention discloses a eutectic of omeprazole and 3, 5-dinitrobenzoic acid, the molar ratio of omeprazole to 3, 5-dinitrobenzoic acid is 1: 1, and compared with omeprazole, the eutectic has higher stability, in-vivo absorption speed and onset speed.

The invention discloses a cross-chain identity privacy protection method based on casual transmission, and the method is characterized in that the method comprises the following steps: S1, employing a negotiation key designed based on a peninsula group replaceable rational function, so as to guarantee that a supervision mechanism and a local enterprise can safely negotiate the key; and S2, when the supervision mechanism carries out identity attribute compliance check on the local enterprise on the local chain, a cross-chain communication scheme based on the casual transmission technology is adopted to realize cross-chain identity authentication. The invention relates to the technical field of identity privacy protection, in particular to a cross-chain identity privacy protection method based on casual transmission. The technical problem to be solved by the invention is to provide a cross-chain identity privacy protection method based on casual transmission, so that on the premise of ensuring the security of a supervision mechanism in a regional stock exchange market, the security authentication and compliance check of identity information of local enterprises on a local chain can be carried out in a cross-chain manner. The method has higher security and is suitable for a plurality of fields such as finance and the like.

This utility model discloses a rotating device for cable winding, belonging to the field of cable processing technology. It includes two sets of parallel and symmetrically arranged supporting rotating mechanisms and a winding reel. The housing of each supporting rotating mechanism contains two sets of supporting rollers that can move axially. The sidewall flange of the winding reel is rotatably connected to the outer walls of the two sets of supporting rollers. At opposite ends of the two sets of supporting rotating mechanisms, two sets of clamping rotating mechanisms are respectively arranged. Each clamping rotating mechanism includes a height-adjustable movable base and a clamping drive assembly installed at the telescopic end of the movable base. The movable base can drive the limiting guide post of the clamping drive assembly to engage with the connecting plate, thereby causing the clamping drive assembly to drive the winding reel to rotate synchronously. This utility model uses two sets of supporting rotating mechanisms installed on the ground to support the cable winding reel, making the winding reel more stable and simplifying the installation and disassembly process, thus improving operational convenience.

The invention provides a CRISPR-Cas9 near-infrared two-region precise light-operated editing system delivery carrier based on an erythrocyte membrane, a preparation method and application, and particularly, the CRISPR-Cas9 gene editing system delivery carrier provided by the invention has the advantages of low cytotoxicity, efficient transfection, high yield, targeting property, space-time controllability, easiness in large-scale production and multifunctionality. Compared with a traditional liposome transfection reagent, the carrier shows lower cytotoxicity, protects the CRISPR / Cas9 compound from being influenced by the in-vivo environment, and ensures that the CRISPR / Cas9 compound is smoothly delivered to target cells. By embedding a specific targeting receptor, efficient targeting delivery is realized, and the pertinence and effectiveness of treatment are improved. And by combining a near-infrared two-region material, the time-space precise control of a CRISPR / Cas9 system is realized, and deeper tissue penetrating power and smaller biotoxicity are achieved. The preparation process is simple, the method is suitable for industrial production and clinical transformation, and new possibility is provided for gene therapy and personalized medical treatment.

The present invention relates to the field of microorganisms, and specifically to providing a new functional lactic acid bacteria expressing ETEC antigens, and a preparation method and application thereof. The recombinant Lactobacillus plantarum expressing ETEC antigens uses Lactobacillus plantarum NC8 as a host bacterium and a pPG612.1 expression vector, wherein the pPG612.1 expression vector contains the FaeC gene or LngC gene of ETEC. The present invention innovatively integrates the FaeC and LngC genes of ETEC into Lactobacillus plantarum NC8 for expression, and can activate the intestinal mucosal immune response by oral administration, which can not only directly counteract the intestinal damage caused by ETEC and protect the intestinal villus structure, but also can regulate the intestinal microenvironment, stimulate the body to produce a systemic immune response, improve the body's ability to resist ETEC infection, reduce the morbidity and mortality of ETEC infection, and thus improve the economic benefits of the pig farming industry.

The invention relates to the field of microorganisms, in particular to novel functional lactic acid bacteria for expressing an ETEC antigen as well as a preparation method and application of the novel functional lactic acid bacteria. According to the recombinant lactobacillus plantarum for expressing the ETEC antigen, lactobacillus plantarum NC8 is used as host bacteria, a pPG612.1 expression vector is used, and the pPG612.1 expression vector contains a FaeC gene or an LngC gene of ETEC. According to the invention, FaeC and LngC genes of ETEC are creatively integrated into lactobacillus plantarum NC8 for expression, and the immune response of intestinal mucosa can be activated in an oral administration mode, so that intestinal injury caused by ETEC can be directly resisted, the villus structure of the intestinal tract can be protected, the whole-body immune response can be generated by regulating the microenvironment of the intestinal tract and stimulating the organism, and the immune response of the intestinal tract can be inhibited. The ETEC infection resistance of the body is improved, and the morbidity and mortality of ETEC infection are reduced, so that the economic benefits of the pig industry are improved.

The present application relates to a kind of selective deoxidation chlorination method of alcohol compound, belong to the technical field of organic synthesis.The method uses the solid chlorinating agent shown in structural formula (I), under the joint action of organic solvent and base, it is reacted under mild conditions at 0-50 ℃, at least one hydroxyl group in alcohol compound can be converted into chlorine atom with high efficiency and high selectivity.The stability of the used chlorinating agent is good, and the safety is high, and it is convenient to store and transport, which overcomes the use limitation of traditional chlorine, sulfonyl chloride and other high-risk reagents.The method is suitable for primary, secondary and tertiary hydroxyl groups, has the advantages of short reaction time, simple operation and wide substrate applicability, and the obtained chlorinated product can be used as an important pharmaceutical and chemical intermediate.The present application effectively solves the problems of existing chlorination method, such as high toxicity, low selectivity and harsh reaction conditions, and has good application prospect.

The invention discloses a broadband impedance online measurement method and system for a power grid side and an equipment side, electronic equipment and a storage medium, and the method comprises the steps: respectively measuring a first voltage and a first current at a common point when a disturbance current is injected at the power grid side and the equipment side; calculating a second voltage and a second current under the disturbance current value when the disturbance current is not injected; the impedance is a ratio of a voltage difference and a current difference, the voltage difference is a difference between the first voltage and the second voltage, and the current difference is a difference between the first current and the second current. According to the method, under the condition that a power system operates normally, the FFT algorithm and the impedance calculation method are combined, the power grid side impedance and the equipment side impedance are measured at the same time, and the stability margin of the system can be analyzed on line according to the impedance measurement result.

The invention discloses a preparation method of ceramic slurry for a solid-state battery. The preparation method specifically comprises the following steps: S1, selecting and proportioning raw materials; s2, a mixing and dispersing process; s3, carrying out post-treatment on the slurry; s4, applying the slurry and assembling the battery; the solid-state battery comprises the following raw materials: ceramic powder, a binder, a thickening agent and a solvent. According to the preparation method of the ceramic slurry for the solid-state battery, through a fine raw material ratio and an innovative mixing and dispersing process, the problem of agglomeration of ceramic particles is effectively solved, uniform dispersion, viscosity adjustment and vacuum defoaming treatment of the ceramic particles in the slurry are realized, and the stability and fluidity of the slurry are ensured; and the homogenization treatment improves the interface contact quality of the slurry and the electrode material, reduces the interface resistance and improves the electrochemical performance of the battery, and the assembled solid-state battery has significant advantages in the aspects of energy density, cycle stability and safety.

The utility model relates to the technical field of constructional engineering, and provides a UHPC light side ditch cover plate which comprises a UHPC panel, a wave-shaped stiffening rib and a plurality of adjustable supporting bases, the UHPC panel comprises an anti-skid layer, a force bearing layer and an anti-crack layer which are arranged from top to bottom, the wave-shaped stiffening rib is arranged at the bottom of the UHPC panel, and the anti-skid layer is arranged at the bottom of the UHPC panel. The wave-shaped stiffening ribs comprise wave-shaped continuous structures arranged on the two sides of the UHPC panel in the length direction, a plurality of straight panel connecting ribs are connected between the two wave-shaped continuous structures, and the multiple supporting bases are arranged at the bottom of the cover plate and used for adjusting the height of the cover plate. According to the scheme, the problems that a traditional side ditch cover plate is large in dead weight, high in maintenance cost and the like are solved, remarkable technical advantages are formed in the aspects of safety, durability, economical efficiency and the like, construction is facilitated, and good application prospects are achieved.

The present invention relates to a system for encoding and correcting the polarization state of the BB84 protocol that implements a method of measuring polarization errors based on performing measurements prior to an information transmission step, which method is applicable to any system in which quantum key distribution (QKD) is to be implemented.

The invention discloses a hollow porous type concentration gradient positive electrode material, wherein the concentrations of nickel ions, cobalt ions and manganese ions contained in the positive electrode material are distributed in a gradient from the center to the surface, and the concentration gradient of nickel ions contained in the positive electrode material decreases from the center of the positive electrode material to the surface of the positive electrode material, and the concentration of nickel ions located at the center of the positive electrode material is 90%-100%, and the concentration of nickel ions located at the surface of the positive electrode material is 60%-70%; the concentration gradients of cobalt ions and manganese ions contained in the positive electrode material both increase from the center of the positive electrode material to the surface of the positive electrode material, and the concentrations of cobalt ions and manganese ions located at the center of the positive electrode material are 0%-5%, and the concentrations of cobalt ions and manganese ions located at the surface of the positive electrode material are 15%-20%. The beneficial effects of the invention are as follows: the hollow porous type concentration gradient positive electrode material of the invention has a concentration gradient structure, has a higher material surface structure stability, and has obvious advantages in terms of cycle performance, rate and safety performance compared with ordinary homogeneous high nickel positive electrode materials.

The utility model provides a conductive structure of a sound wave motor and an electric toothbrush, and belongs to the field of electric toothbrushes, the conductive structure comprises a sound wave motor body, a hollow conductive motor shaft and a conductive assembly, the motor shaft of the sound wave motor is of a hollow conductive structure, and the interior of the motor shaft serves as a wiring channel; the conductive assembly penetrates through the body from the central axis of the crankshaft to be externally connected to form a first conductive circuit, and the motor shaft of the conductive assembly serves as a second conductive circuit through the conductivity of the conductive assembly. The two ends are respectively connected with an electric element and a power supply to form an access; the characteristics of the structure of the sound wave motor are fully utilized, and only the crankshaft needs to be arranged in a hollow manner without greatly modifying the structure of the motor; the first power connection output end and the second power connection output end are both integrated on the motor shaft, although the motor vibrates in a high-frequency reciprocating mode, the power connection efficiency is not affected, additional wiring layout is not needed, the two output ends can be installed in an external assembly mode, and the motor has the advantages in safety and convenience.

An ophthalmic preparation for treating macular edema, optic neuritis and non-infectious endophthalmitis. The ophthalmic preparation is a preparation composed of an active ingredient for treating eye diseases and an ophthalmic preparation carrier or auxiliary material; the active ingredient for treating eye diseases is a glucocorticoid medicine and / or a non-steroidal medicine; the ophthalmic preparation carrier or auxiliary material comprises the following ingredients: a surfactant, an ionic polymer and a solvent, or the ophthalmic preparation carrier or auxiliary material contains the following ingredients: povidone with low polymerization degree, povidone with moderate polymerization degree and a solvent. The ophthalmic preparation can carry (wrap) the glucocorticoid and / or the non-steroidal medicines to penetrate through the anterior segment of eyes and be conveyed to the posterior segment of eyes to treat the macular edema, the optic neuritis and the non-infectious endophthalmitis in an eye drop administration mode, and the ophthalmic preparation has extremely excellent clinical use value and positive social significance.

The invention discloses a method for distinguishing attacks and faults of a catalytic cracking fractionation system, and belongs to the field of industrial control system information security. The method comprises the following steps: firstly, extracting abnormal states of system information domain equipment nodes and physical domain variable nodes, splicing multi-domain abnormal characteristics and then training a KNN model; the modes of the system in attack, fault and normal states are learned; and finally, carrying out online attack and fault discrimination by using the trained KNN model. According to the method, the behavior characteristics of attacks and faults can be comprehensively described by extracting the multilateral characteristics of the information domain and the physical domain, the limitation that abnormal reasons are analyzed only from the perspective of the physical process is overcome, and the distinguishing accuracy can be effectively improved; in addition, the KNN model can effectively reduce the discrimination error problem caused by intersection of individual samples of attack classes and fault classes.

The utility model discloses a child seat with an adjustable backrest length. The child seat comprises a seat assembly. The backrest piece can rotate relative to the seat assembly so as to adjust the inclination angle of the backrest; the backrest telescopic part is mounted on the backrest part in a sliding manner and is used for adjusting the effective length of the backrest; one end of the connecting belt is connected with the backrest telescopic piece, and the other end of the connecting belt is connected with the seat assembly; one end of the reset piece is connected with the backrest telescopic piece, and the other end of the reset piece is connected with the backrest piece or the seat assembly; the connecting point of the connecting belt and the seat assembly is different from the rotating point of the backrest piece and the seat assembly; when the backrest piece rotates, the backrest telescopic piece can slide relative to the backrest piece through cooperation of the connecting belt and the reset piece, and the effective length of the backrest is automatically adjusted. Through the synergistic effect of the connecting belt and the reset piece, the backrest telescopic piece can automatically slide along with rotation of the backrest piece, the effective length of the backrest is automatically adjusted, and comfort and convenience are improved.

The present invention discloses a method for sharing and protecting wind power safety data based on federated learning and blockchain, which relates to the field of new generation information technology for data processing, and includes the following steps: Step 1, establishing a confidential data model based on federated learning; Step 2, establishing proxy sharing integration based on blockchain; Step 3, establishing a data leakage risk assessment model based on a federated optimization algorithm. The technical solution provided by the present invention enhances security through federated learning and blockchain technology; utilizes differential privacy and encryption algorithms to ensure data privacy protection during data sharing; reduces data transmission requirements through distributed data processing, reduces system performance overhead, and improves overall efficiency; introduces a data leakage risk assessment model, which can monitor and warn potential security threats in real time, and enhances the system's warning capability.

The invention discloses a nitrendipine and polyvinylpyrrolidone co-amorphous substance, the weight ratio of nitrendipine to polyvinylpyrrolidone is 1: 1, and compared with nitrendipine, the nitrendipine and polyvinylpyrrolidone co-amorphous substance has higher solubility, dissolution rate and stability.