14 results about "Hydroxyacetone" patented technology

The present invention relates to a novel method for preparing a benzyl α-hydroxyketone derivative by mono-α-arylating O-protected hydroxyacetone with a palladium catalyst, followed by deprotection.

The application provides a method for efficiently reducing imines to synthesize alpha-amino acid compounds and application thereof, and belongs to the technical field of chemical synthesis. The method comprises the following steps: using hydroxyacetone as a reducing agent, and reducing imines under the catalysis of aza-cycloalkyl carbine catalysts to obtain alpha-amino acid compounds. The method uses hydroxyacetone as a reducing agent, and adopts aza-cycloalkyl carbine catalysts to realize the reduction of imines under mild conditions. The method is simple in operation, low in cost, green and pollution-free, suitable for industrial production, and solves the problems of non-cleanness caused by the use of metal catalysts in the existing imine reduction method, use of dangerous and unstable reducing agents, harsh reaction conditions and high production cost.

This invention belongs to the field of catalysis technology, and specifically relates to a method for the liquid-phase catalytic oxidation of 1,2-propanediol to prepare hydroxyacetone. The catalyst is an M-Zr-UiO-66 catalyst, where the metal M is selected from Fe, Cr, Cu, and Co, and the ligand is terephthalic acid. The catalyst preparation and catalytic reaction process of this invention are simple, the catalyst is reusable, and it is environmentally friendly. Using the catalyst and corresponding catalytic conditions of this invention, a good yield of hydroxyacetone can be obtained under relatively mild conditions. The main product is hydroxyacetone, and the byproduct is acetone. The selectivity of the main product can reach over 80%, and the conversion rate of 1,2-propanediol can reach over 14%.

The invention relates to a dihydroxyacetone phosphate transaminase CJ1361 mutant with improved stability, and a gene recombinant bacterium containing the dihydroxyacetone phosphate transaminase CJ1361 mutant and an enzyme liquid of the gene recombinant bacterium as biocatalysts, which are used for synthesizing serinol by a microbial fermentation method. Compared with the wild type dihydroxyacetone phosphate transaminase CJ1361, the yield of serinol produced by the dihydroxyacetone phosphate transaminase CJ1361 mutant provided by the invention is remarkably improved.

The invention provides a property-changed dihydroxyacetone kinase mutant and application thereof, and relates to the technical field of enzyme engineering. Through rational design and molecular modification, wild dihydroxyacetone kinase is subjected to single-point mutation and combined mutation, a series of enzyme mutants with enhanced thermal stability are obtained, and the catalytic activity of the mutants under the high-temperature condition is remarkably superior to that of wild enzymes. The invention further provides a multienzyme coupling reaction system containing the dihydroxyacetone kinase mutant, and the multienzyme coupling reaction system is used for efficiently catalyzing the process of synthesizing lactic acid by taking dihydroxyacetone as a substrate. The thermostable dihydroxyacetone kinase mutant provided by the invention solves the key bottleneck that a wild enzyme is easy to thermally inactivate under industrial application conditions, and has important industrial application prospects.

The present invention relates to a binder composition comprising component A comprising polymer(s) A1 and optionally component B comprising component B1 which is selected from the group consisting of a mono-saccharides, disaccharides, hydroxyacetone, glycolaldehyde and mixtures thereof, wherein polymer(s) A1 comprises at least 70 wt.-% poly(amino acid)s based on the total weight of the polymers) A1 and has (have) a total weight average molecular weight Mw, total of 800 g / mol to 10.000 g / mol, wherein the binder composition comprises 60 to 100 wt.-% polymer(s) A1, and 0 to 40 wt.-% component B1, based on the total weight of the sum of polymer(s) A1 and component B1, wherein the weight amounts of the polymer(s) A1 and component B1 are selected such that the total weight of the sum of polymer(s) A1 and component B1 is 100 wt.-%.

The disclosure relates to a process for producing hydroxyacetone, by catalytic dehydration of glycerol in the presence of a copper catalyst slurry comprising a copper catalyst and a polymeric material or an ionic liquid.

The present invention relates to a process for preparing bisphenol A in the presence of at least two impurities being selected from the group consisting of 2-methylbenzofurane, hydroxyacetone, alpha-methylstyrene, acetophenone, benzene and / or cumene without poisoning the catalyst system comprising an ion exchange resin catalyst and a sulfur containing cocatalyst, wherein at least part of the sulfur containing cocatalyst is not chemically bound to the ion exchange resin catalyst. Moreover, the present invention provides a process for preparing polycarbonate.

The application provides a shaped hydroxypropanone catalyst which is prepared from a hydroxypropanone catalyst powder, a binder, a pore-forming agent and a dilute acid solution. The hydroxypropanone catalyst provided by the application has a catalyst reaction life of not less than 600 hours in a reaction of preparing hydroxypropanone by dehydrating glycerol.

The application discloses a Yarrowia lipolytica gene engineering bacterium for producing erythritol by glycerol, and the Yarrowia lipolytica gene engineering bacterium is obtained by random insertion mutation mediated by non-homologous end connection, and strains with high cell growth and high erythritol yield are screened. Further, the gene engineering bacterium overexpresses glycerol dehydrogenase gene GCY3 or ARA1 and dihydroxyacetone kinase gene DAK2 of a glycerol metabolism dihydroxyacetone pathway. Further, the gene engineering bacterium overexpresses transketolase gene TKL1 and transaldolase gene TAL1 of a non-oxidative pentose phosphate pathway. The application further discloses a construction method and application of the gene engineering bacterium. The superior gene engineering bacterium obtained by constructing a mutant library has the characteristics of tolerating high-concentration glycerol, and the substrate conversion rate and glycerol utilization rate are significantly higher than those of a starting strain.

Selective hydrogenation processes are disclosed that can upgrade impure feeds, such as those obtained from biomass and containing a number of small (e.g., 2-6 carbon atom) molecules having aldehyde and / or ketone carbon atoms. For example, whereas glycolaldehyde and its methylated derivative, hydroxyacetone (acetol) are both high value intermediates for certain downstream processing reactions, they are normally recovered in a condensate from pyrolysis of carbohydrates (e.g., aldose-containing sugars) together with glyoxal and its methylated derivative, pyruvaldehyde. The selective hydrogenation of these compounds bearing two carbonyl carbon atoms, without over-hydrogenation to ethylene glycol and propylene glycol, can increase the concentration of the desired intermediates. These beneficial effects of selective hydrogenation may be achieved through the use of a hydrogenation catalyst comprising noble metals such as Ru and Pt.

The disclosure relates to a process for producing hydroxyacetone, by catalytic dehydration of glycerol in the presence of a copper catalyst slurry comprising a copper catalyst and a polymeric material or an ionic liquid.

The present invention relates to [1] a dispersion of metal fine particles containing hydroxyacetone and propylene glycol, in which a cumulant average particle size of the metal fine particles is not less than 0.01 μm and not more than 0.1 μm, and [2] an ink containing the dispersion of metal fine particles as described in the above [1].

The invention discloses a preparation method of a gadotetrol isomer. The method comprises the following steps: by taking cycleanine as an initial raw material, firstly reacting with tert-butyl bromoacetate to obtain a trisubstituted intermediate; then in the presence of a reducing agent, carrying out reductive amination reaction with hydroxyacetone, and directionally introducing a 1-hydroxy-propyl-2-yl side chain; and removing a protecting group through alkaline hydrolysis, carrying out chelation reaction with a gadolinium source, and purifying to obtain the gadotetrol isomer. The method adopts a reductive amination strategy to solve the problem of regioselectivity, is combined with an alkaline hydrolysis process, has the advantages of short synthesis route, high total yield, mild reaction conditions, simplicity and convenience in operation and the like, effectively avoids the use of high-pressure hydrogenation and highly toxic reagents, and is suitable for industrial preparation.