Process for extracting tanshinone

An extraction method and technology of tanshinone, applied in the field of medicine, to achieve the effects of easy industrialization, increased column capacity, and reduced product cost
CN1670019AActive Publication Date: 2005-09-21TIANJIN TASLY MORDEN TCM RESOURCES
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
TIANJIN TASLY MORDEN TCM RESOURCES
Publication Date
2005-09-21

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Abstract

The invention relates to a method for extracting tanshinone which comprises the following two steps: first, alcohol extraction process: separating the extraction liquid and dregs with the danshen liposolubility content from danshen medicine materical crude slices or disintegrated danshen medicinal materials by bath method, hypersonic extraction or microwave extraction in condition of normal temperature or heating, and reserving, adding correct concentration alcohol into the dregs, inverse flow extracting with heating to get the extraction, which combined with the extraction get from the first extraction, removing the solid impurities by the methods of filtration, centrifugation or deposition, and reserving. Second, isolation method separation: adding the medicine liquid get from the said alcohol extraction process to a macroreticular resinous adsorbent column, gradient eluting by alcohol with a finite concentration respectively to get the extraction I (with cryptotanshinone and dihydrotanshinone I) and extraction II (with tanshinone IIA and tanshinone I).
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Description

technical field

[0001] The invention relates to the field of medicine, in particular to a method for extracting tanshinone. Background technique

[0002] Danshen (Salivia miltiorrihiza Bunge) is a commonly used traditional Chinese medicine in my country. It has many clinical effects, such as analgesia and antipruritic. It has a certain curative effect on liver shrinkage for gynecological diseases and jaundice infectious hepatitis. Pharmacological efficacy in recent years has proved that Salvia miltiorrhiza also has the effect of improving coronary circulation, inhibiting inflammation and detumescence of thrombotic diseases, and has been marketed as a patented medicine. Tanshinone compounds are active ingredients in the soluble ingredients of salvia miltiorrhiza, and are index ingredients of various medicines containing salvia miltiorrhiza.

[0003] At present, there are many reports on the extraction methods of tanshinone. Cao Mingcheng et al [E...

Claims

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