25results about "Crystallization conditions screening" patented technology

The invention provides an ultrasonic-assisted gamma-aminobutyric acid crystallization particle size regulation and control method, which comprises the following steps: removing impurities and decolorizing gamma-aminobutyric acid-containing feed liquid, heating, stirring and concentrating to a nearly saturated state, then carrying out ultrasonic-assisted crystallization, cooling, aging and suction filtration to obtain coarse crystals, and finally washing and drying to obtain target crystals. According to the method, a synergistic process of raw material liquid pretreatment, evaporation concentration-ultrasonic-cooling coupling crystallization, aging and post-treatment is adopted, an ultrasonic cavitation effect is utilized to reduce a nucleation barrier, and a supersaturation degree precise control and gradient cooling strategy is combined, so that grain size refinement, obvious narrowing of distribution and effective inhibition of agglomeration of crystals are realized; the median particle size of the crystal can be controlled to be smaller than or equal to 200 microns, the particle size distribution span is smaller than or equal to 1.5, the agglomeration phenomenon is remarkably inhibited, the crystal form is kept stable, the crystal habit is complete and smooth, the crystal product quality and the process efficiency are remarkably improved, and the method has important industrial application value.

The invention provides a production device and process for increasing the content of magnesium citrate crystals. The problems that in the prior art, the impurity co-crystallization rate is high, and crystal forms are difficult to control are solved. The device comprises a gradient temperature control multi-stage crystallization device and a crystal form directional regulation and self-adaptive separation system. The gradient temperature control multi-stage crystallization device is composed of a main crystallizer, a gradient temperature control system, an ultrasonic-assisted system and a liquid phase partition circulating system, and the crystallization environment is accurately controlled through the temperature gradients of five independent temperature zones. The crystal form directional regulation and self-adaptive separation system is composed of a seed crystal dynamic inoculation device, an electric field auxiliary directional crystallization system, a real-time crystal morphology analysis system and a self-adaptive separation system, and the crystal morphology and particle size distribution can be accurately controlled. According to the process disclosed by the invention, the main content of magnesium citrate is increased to 98.8 + / -0.3%, heavy metal impurities and organic impurities are respectively reduced by 70% and 75%, the crystal form consistency is increased to 96 + / -2%, the production period is shortened by 33%, and the process has remarkable economic benefits and social benefits.

The invention relates to the technical field of mixing equipment, and discloses a mixing preparation device and method for a plant growth regulator containing a silicon element. The mixing preparation device of the silicon-containing plant growth regulator comprises a stirring main kettle, an online monitoring unit, a solid-liquid separation unit and a control unit, the stirring main kettle is used for carrying out a liquid-phase chemical reaction and separating out a solid product in situ, and is provided with a stirring piece; and the on-line monitoring unit is used for acquiring a reaction process signal and a crystallization state signal in the main stirring kettle in real time. The online monitoring unit, the solid-liquid separation unit and the control unit are arranged and cooperatively used, dynamic optimization management of the reaction crystallization process is achieved, the solid-liquid separation unit moves out crystals in time and circularly supplements materials, the problem that the crystals are secondarily wrapped is solved, meanwhile, reaction balance is pushed to move rightwards, and the reaction efficiency is improved. The conversion rate and the yield are improved.

The invention provides a cooling crystal obtaining system for generating a chelated fertilizer, and relates to the technical field of mixed fertilizer manufacturing, the cooling crystal obtaining system comprises a crystallization bin, the middle of the bottom of the crystallization bin is connected with a circulating pipeline, and the front side of the lower end of the circulating pipeline is connected with a discharge pipeline; a chelating bin is fixedly arranged at the top of the crystallizing bin, a top cover is fixedly arranged at the top of the chelating bin, and a feeding pipe is fixedly connected to the front upper part of the top cover; six groups of expansion grooves are integrally arranged below the outside of the chelating bin, and semiconductor refrigeration plates are fixedly arranged outside the expansion grooves; in the system, the chelating bin and the crystallizing bin continuously convey liquid materials through the air pressure and communicating vessel principle, circulating backflow retreatment of the uncrystallized liquid materials is achieved through the circulating device, the flow direction of the liquid materials is accurately regulated and controlled in cooperation with the electric cylinder A and the electric cylinder B, and the whole process of raw material supplementation, crystal generation and crystal separation can be completed without shutdown; the problems that traditional evaporative crystallization is low in efficiency and continuous operation cannot be achieved are solved, and the yield of chelated fertilizer crystals in unit time is remarkably increased.

The present application relates to a method for improving the grade of potassium chloride in the process of preparing potassium chloride by using a vacuum crystallizer, comprising a potassium chloride crystallization step (S1), a fine potassium mother liquor is introduced into a DTB vacuum crystallizer for crystallization, part of small particle nuclei enter the circulating channel, are dissolved and then returned to the DTB vacuum crystallizer, and a slurry containing large particle nuclei is discharged to obtain a large particle crystal slurry; a screening step (S2), the large particle crystal slurry is screened by a first screening device to obtain a first screen oversize and a first screen undersize, a second screening device is used to screen the first screen undersize to obtain a second screen oversize and a second screen undersize; a large particle size nucleus treatment step (S3), the first screen oversize is dissolved with fresh water to obtain a targeted mother liquor, and the targeted mother liquor is returned to the circulating channel and then into the DTB vacuum crystallizer for continuous crystallization; and a small particle size nucleus treatment step (S4), the second screen undersize is returned to the inside of the DTB vacuum crystallizer for continuous crystallization. The present application can improve the grade of potassium chloride.

The application discloses a method for improving stability of organic materials, comprising the following steps: conducting trial production under the same feeding amount and the same temperature value, obtaining test data of relative content of stable solid and holding time by changing the holding time, and obtaining conversion time data of metastable solid converted into stable solid; obtaining a trend line formula between the relative content of stable solid and the conversion time and correcting the trend line formula; obtaining a mathematical model between the feeding amount and the conversion time required when the relative content of stable solid is 100% through the trend line formula and the trial production; obtaining the expected holding time or the maximum feeding amount in the mathematical model, and judging whether the production requirement is met; if the production requirement is not met, changing the temperature value and repeating the previous step to correct the mathematical model until the expected holding time or the maximum feeding amount meeting the production requirement is obtained. The application can effectively solve the dependence on the experience of process personnel in the process amplification.

The present application provides method for operating a crystallization process model generating device. The method includes receiving selections of a solubility template, a particle size distribution template, a crystallization device template, a process time template, and a concentration factor template provided in a certain order, respectively, performing modeling of a crystallization process model by combining the selected templates, and when the crystallization process model is built, receiving an input of a condition for an injection liquid to perform a simulation for deriving a crystal suspension by inputting the injection liquid into the crystallization process model.

A crystallizer modeling method according to an embodiment of the present disclosure may comprise the steps of: calculating a first stress distribution of a first crystallizer; setting a parameter required for modeling a second crystallizer scaled down from the first crystallizer; calculating a second stress distribution of the second crystallizer on the basis of the set parameter; comparing the second stress distribution with the first stress distribution; determining a parameter for calculating a second stress distribution matching the first stress distribution; and designing the second crystallizer on the basis of the parameter.

The application discloses an ultrafine ammonium paratungstate evaporation crystallization device and a crystallization method. The device comprises a shell, an evaporation barrel is arranged at the middle of the top end of the shell, a feeding pipe and a collecting pipe are arranged at the top end of the evaporation barrel, the other end of the collecting pipe is connected with the shell, the collecting pipe is arranged in a U shape, a heater is arranged at the bottom of the evaporation barrel, and a collecting assembly is arranged in the shell through the collecting pipe. The device has the beneficial effects that the collecting assembly, the flow guiding assembly, the drainage assembly and the screening assembly are arranged, the steam and the ammonia gas generated during evaporation can be utilized again, the ammonia gas and the steam can be filtered at the same time, the high energy of the high pressure of the ammonia gas can drive the screening assembly to screen the ammonium paratungstate crystals, and therefore, the device for separating the ammonia gas and the water vapor is not needed during the crystallization of the ammonium paratungstate, and the working efficiency is greatly improved.

The present invention relates to a method for detecting the formation of a deposition layer on a cooled surface being provided inside a vessel comprising at least one agitator, in particular for detecting the formation of a crystal layer on a cooled surface being provided inside a scraped heat exchanger and preferably in a scraped crystallizer, wherein the method comprises the following steps: a) operating the vessel being filled with a liquid, a suspension or an emulsion by driving at least one agitator and by cooling at least one surface and b) time-resolved determining during the operation of the vessel in step a) the acceleration of the vessel and determining, whether the acceleration of the vessel has been increased within a first predetermined time period by more than a predetermined threshold, wherein the length of the first predetermined time period is at most 1 hour and the predetermined threshold is an increase of the acceleration of the vessel of at least 10% of the acceleration of the vessel before the start of the first predetermined time period.

To provide a method for manufacturing high-purity molybdenum oxychloride and a manufacturing apparatus thereof.SOLUTION: The present invention relates to a method for manufacturing molybdenum oxychloride including: a reaction step of adding molybdenum powder, chlorine gas, and oxygen to a reactor and heating them to prepare molybdenum oxychloride (MoO2Cl2); a solidification and condensation step of transferring a reacted material in the reactor from the reactor to a condensation tank to solidify the reacted material on a surface of the condensation tank; a liquefaction step of heating a product solidified in the solidification and condensation step to convert the product into a liquid phase; and a purification step of filtering the product liquefied in the liquefaction step to increase purity, and a manufacturing apparatus thereof.SELECTED DRAWING: Figure 1

The invention belongs to the technical field of lithium battery materials, and particularly relates to a method for reducing the residual of a sodium bis (fluorosulfonyl) imide solvent and improving the uniformity of crystal particles. The method comprises the steps of 1) NaFSI synthesis, 2) recrystallization, 3) post-treatment and the like. According to the invention, the particle size distribution of NaFSI can be effectively controlled by combining real-time monitoring and temperature adjustment of the online particle size detector. In addition, the crystallization process is controlled through temperature, so that the crystals reach a stable state, solvent residues are reduced, post-treatment is easier, the solvent removal time is shortened, or the process is simplified. Through the gradient slow cooling process, stable NaFSI crystals are generated in the crystallization process, reagents are effectively prevented from being contained in the NaFSI crystals, the post-treatment solvent residual time is shortened, and material partial decomposition caused by long-time heating and drying is avoided. According to the invention, the particle size distribution is controlled, so that the NaFSI crystal particles are obviously increased.

The invention relates to a method of forming a co-crystal, the method comprising forming a droplet comprising a first liquid and a second liquid; wherein the first liquid comprises a chemical molecule, or a salt thereof, and a co-former, or a salt thereof, and the second liquid is an oil. The invention also relates to a method of screening for co-crystals of a chemical molecule, or salt thereof, the method comprising said method of forming a co-crystal.

A refining method according to the present invention is a refining method for crystallizing a compound with at least one crystal form, including: setting, as a target wavelength, a specific infrared wavelength at which a specific crystal form precipitates from a solution of the compound dissolved in a solvent; and using an infrared radiation apparatus capable of emitting infrared radiation including the target wavelength to evaporate the solvent and precipitate the specific crystal form while irradiating the solution with infrared radiation including the target wavelength. The specific infrared wavelength is preferably set as the target wavelength based on an infrared absorption spectrum of the crystal form and the dissolution rate of the compound in the solvent.

The application relates to the technical field of fine chemical production, and particularly discloses a crystallization process of short-rod-shaped ivermectin, which comprises the following steps: dissolving ivermectin crude product in a crystallization solvent, heating to 50-55 DEG C, adding a crystallization agent, uniformly mixing, then cooling to 35-40 DEG C at a rate of 0.1-0.3 DEG C / min, adding ivermectin crystal seeds, continuously cooling to 5-15 DEG C, and incubating and crystallizing to obtain ivermectin products. The crystallization process of ivermectin provided by the application realizes effective control of the particle size and crystal habit of ivermectin products in the crystallization process by adopting a combination strategy of selecting a specific crystallization solvent, adding a crystallization agent and crystal seeds at specific stages, controlling the cooling rate and the incubation time, obtaining short-rod-shaped ivermectin products with uniform particle size distribution, and the products have good fluidity, are convenient for subsequent preparation application, do not need repeated crystallization for multiple times, effectively reduce the cost of the crystallization process, and have extremely high practical application value.

The invention relates to anti-solvent crystallization equipment for a cyanide-free electrogilding solution. The anti-solvent crystallization equipment comprises a tank body; the stirring mechanism comprises a stirring paddle, and a drainage channel is arranged in the stirring paddle in a penetrating manner; the crystal forming mechanism comprises a forming shell, and a movable push plate is arranged in the forming shell; the movable baffle plate is driven by the longitudinal driving mechanism and moves downwards to shield the crystal output port, and a high-concentration ethanol area is formed in the forming shell, so that a sodium gold sulfite solution is mixed with ethanol, penetrates through the flow blocking column and is diffused from the ethanol outlet, and the sodium gold sulfite forms porous blocky crystals in the forming shell; after the movable baffle moves upwards, the crystal output port is opened, and the movable push plate moves towards the outer side of the forming shell, so that the porous blocky crystals in the forming shell are output; the intercepting cage body is arranged on the periphery of the crystal forming mechanism, and the porous blocky crystals are collected by the intercepting cage body after being output.

The application discloses a probiotic crystal ball production device and a probiotic crystal ball, and belongs to the field of biopharmacy, comprising a storage tank, a titration pumping module, a first tank body and a second tank body, the titration pumping module is communicated with the storage tank, a feeding port and a discharging port are arranged on the first tank body, and the outlet end of the titration pumping module extends into the first tank body through the feeding port; a liquid supplementing pipe is further arranged on the first tank body; a feeding pipe is arranged on the top of the second tank body, and a discharging pipe is arranged at the bottom of the second tank body, the feeding pipe is connected with the discharging port of the first tank body; a spiral generating device for generating spiral water flow is arranged in the second tank body, and the discharging pipe is further connected with a separating device; the first tank body is used for realizing primary hardening, a protective film is formed on the surface of liquid drops, then the semi-hardened liquid drops are driven to rotate by the intermolecular force and the spiral water flow in the second tank body, and the liquid drops are gradually hardened into crystal balls, and the roundness and production efficiency of the crystal balls can be effectively improved, and the cleanliness of the process flow is ensured.

The application provides a particle size control method for ultrasonic-assisted gamma-aminobutyric acid crystallization. After impurity removal and decolorization of a gamma-aminobutyric acid feed liquid, the feed liquid is concentrated to a near-saturated state through heating and stirring, then ultrasonic-assisted crystallization is performed, cooling and temperature reduction are performed, aging is performed, and crude crystals are obtained through suction filtration, and finally, the target crystals are obtained through washing and drying. The method is a synergistic process of raw material liquid pretreatment, evaporation concentration-ultrasonic-cooling coupled crystallization, aging and post-treatment, uses ultrasonic cavitation effect to reduce nucleation potential barrier, and combines supersaturation precision control and gradient cooling strategies to realize crystal particle size refinement, obvious narrowing of particle size distribution and effective inhibition of agglomeration, so that the median particle size of the crystals can be controlled to be less than or equal to 200 microns, the particle size distribution span is less than or equal to 1.5, the agglomeration phenomenon is significantly inhibited, the crystal form remains stable, the crystal habit is complete and smooth, the crystal product quality and process efficiency are significantly improved, and the method has important industrial application value.

Processes for treating an aqueous composition comprising lithium sulfate and sulfuric acid. The processes comprise evaporatively crystallizing the aqueous composition comprising lithium sulfate and sulfuric acid under conditions to obtain crystals of lithium sulfate monohydrate and a lithium sulfate-reduced solution; and optionally separating the crystals of the lithium sulfate monohydrate from the lithium sulfate-reduced solution. The processes optionally further comprise concentrating the lithium sulfate-reduced solution under conditions to obtain an acidic condensate and a concentrate comprising sulfuric acid.

The application discloses an indoxacarb finished product crystallization method, which comprises a crystallization cylinder mechanism, a lifting cover plate mechanism, a crystallization plate mechanism, a driving mechanism and a collecting disc. When used, a mixed solution of indoxacarb and an organic solvent is poured into a crystallization chamber, three to five parts by mass of indoxacarb finished product is added as a crystal seed, a pipeline valve on a feeding pipe is opened, the feeding pipe is connected with a refrigerant delivery pipe, a pipeline pump is used to deliver the refrigerant into a distribution part and then into the crystallization plate mechanism through distribution holes one and two, pump one and pump two are started to circulate the refrigerant between a circulating refrigeration pipe and a distribution channel of the distribution part, so that the temperature of the surface of the crystallization plate shell is rapidly reduced, indoxacarb crystals are precipitated on the surface of the crystallization plate shell, the temperature of the surface of the crystallization plate shell is rapidly reduced through accurate control, and the efficiency of the precipitation of the crystals is improved.

The present application relates to a kind of cyanide-free electroplating gold solution anti-solvent crystallization equipment, comprising: tank body;Stirring mechanism, including stirring paddle, flow channel is arranged in stirring paddle;Crystal forming mechanism, crystal forming mechanism includes forming shell, and forming shell is provided with movable push plate;Movable baffle, by longitudinal drive mechanism drive, movable baffle is shielded after downward movement crystal output, and form high concentration ethanol area in forming shell, so that sodium gold sulfite solution is mixed with ethanol, then pass through flow barrier column and diffuse from ethanol outlet, so that sodium gold sulfite forms porous block crystallization in forming shell, movable baffle is opened after upward movement crystal output, and movable push plate is moved towards forming shell outside, to form porous block crystallization in forming shell is exported;Intercept cage, set in the periphery of crystal forming mechanism, and porous block crystallization is collected after being exported by intercept cage.

Described are systems and methods for crystallizing a substance in a microgravity environment. Methods can include receiving a plurality of reagents from at least one source into a reactor. The reactor can include at least one channel with at least a first portion and a second portion for processing the plurality of reagents. Methods can include contacting the plurality of reagents within the first portion. The first portion can include a plurality of periodic or non-periodic throttling nodes, optimizing a type of mixing of the plurality of reagents. Methods can include displacing the plurality of reagents using a first set of conditions when the plurality of reagents are within the first portion. Methods can include contacting the subset of the plurality of reagents within the second portion. The second portion can be a uniform profile for optimizing crystallizing using a second set of conditions sufficient to yield a crystallized substance.

The application discloses L-alanine crystals and a preparation method thereof, relates to the technical field of L-alanine crystal preparation, and is characterized in that a morphology regulator is added into an aqueous solution containing L-alanine, crystallization is performed, and L-alanine crystals are obtained; the morphology regulator comprises any one or a combination of more than one of paclitaxel, isosorbide mononitrate and lactic acid. In the application, the morphology regulator is added into the aqueous solution containing L-alanine, the growth of the long axis of the crystals is inhibited, the growth of the short axis is promoted, and short rod-shaped L-alanine crystals are obtained. The application has the advantages of simple process, easy control and environmental protection.

The present application relates to the technical field of industrial solid waste resource utilization, and particularly relates to a system for extracting high-purity potassium salt by using cement bypass ash, which comprises: a magnetic separation module for separating Fe3O4 magnetic phase in the bypass ash under a 0.8-1.2T gradient magnetic field, a dynamic activation module for two-stage calcination under the assistance of NH4Cl, a countercurrent leaching module for realizing hydrochloric acid-ammonium fluoride synergistic leaching under the condition of pH 0.5-2.5 through a three-stage series reactor, an ion sieve separation module comprising a bipolar membrane electrodialysis unit and a Li + type K-LTL molecular sieve adsorption tower, and a crystal phase regulation module for preparing potassium salt crystals with Cl ‑ content ≤0.1% by using real-time feedback of super-saturation through conductivity; and a cyclic regeneration module. After purification, the potassium salt in the present application can be directly packaged and sold in the market, and the remaining bypass ash can continue to be reused to produce cement, and the comprehensive cost is reduced by more than 35% compared with the traditional process, thereby providing an integrated solution of “efficient potassium extraction-high-purity separation-zero waste recycling” for the solid waste of the cement industry.

The invention discloses a spiral feeder for continuous crystallization of monopotassium phosphate and a conveying method of the spiral feeder, and relates to the technical field of rotary spiral feeding. The spiral feeder comprises a pusher, the exterior of the pusher is rotationally connected with a shell, the bottom end of the shell is fixedly connected with a base, and the left side of the shell is fixedly connected with a feeding hopper; a temperature controller fixedly connected with the top end of the shell is arranged on the right side of the feeding hopper, a discharging port is formed in the bottom end of the right side of the shell, a scraping and brushing mechanism is arranged below the pusher, a drying mechanism is arranged on the right side of the pusher, and a recycling mechanism is arranged on the right side of the pusher. The device can scrape and clean crystals and solutions adhered to the feeder and the side wall of the closed container to prevent more and more crystals and solutions from existing in the feeder, so that the reduction of a clean space in the feeder can be effectively avoided, the reduction of crystallization efficiency is prevented, the crystallization time can be shortened, the yield and purity of a final product are improved, and the production cost is reduced. In addition, the channel of the feeder can be dredged and prevented from being blocked.