35results about How to "Meet the requirements of therapeutically effective dose" patented technology

The invention provides a group of polyhydroxy stilbene compounds, their preparing process and use for suppressing and eradicating SARS coronavirus. The preparing process comprises, preparing phosphonic ester by reacting multi-alkyl substituted chloro (bromo) methoxyl or pyridine compounds with triethyl phosphate, then reacting phosphonate ester compound with multi-alkyl (oxy) phenylpyridine methyl aldehyde to obtain multi-alkyl (oxy) stilbene compounds. Finally acting with boron tribromide to obtain polyhydroxy stilbene compounds with substituent groups.

The invention relates to a traditional Chinese medicine composition taking Rhodiola rosea extract, cordyceps militaris extract and rhein as the major components, a preparation method and a medical composition of the traditional Chinese composition as well as applications of the traditional Chinese medicine composition and medical composition in preventing and/or treating insulin resistance and related metabolic syndrome thereof.

The invention relates to a method for preparing the hypoglycemic extractive from Balaophora L, wherein it also provides the application in drug and health-care product, especially for treating and preventing diabetes, etc.

The invention discloses application of Chinese violet in resisting diabetes mellitus and preventing relative metabolic diseases, in particular extract and effective parts of viola yedoensis makino, a preparation method of the extract and the effective parts, a medicine composition containing the extract or effective parts of the Chinese violet, and application of products for preventing diabetes mellitus and relative metabolic diseases.

An application of schisandrin A in treating the drug-resistant tumor is disclosed. It can be used in conjunction with antineoplastic for increasing the sensitivity of tumor to antineoplastic.

The present invention discloses the application of cnidiadin in preparing medicine for preventing and treating sexual dysfunction.

The invention provides an isolicoflavonol-containing antitumor drug, wherein suspension type injections, tablets and microcapsules are processed and manufactured by taking isolicoflavonol as the active ingredient and combining with pharmaceutically acceptable auxiliary materials and carriers. The antitumor drug is used for preventing and treating breast cancer, ovarian cancer, cervical cancer and colon cancer and usual gastrointestinal cancer, lung cancer, kidney cancer, bladder cancer, prostate cancer, skin cancer, head and neck cancer, brain tumor or leukemia. Confirmed by pharmacological experiments and antitumor effect comparing evaluation, the isolicoflavonol coming from traditional Chinese medicine liquorice has the function of inhibiting the generation of new blood vessels and is capable of achieving the purpose of resisting tumors through inhibiting the generation of the new blood vessels of the tumors. The invention provides an industrial preparation method of the isolicoflavonol serving as a medicinal material, comprising extraction, separation, grain size specification and other concrete process requirements.

The invention belongs to the technical field of medicines, relates to application of a dianthrone compound in preparation of a medicine for treating diabetes or hyperlipidemia, and particularly discloses application of the dianthrone compound shown in a general formula (I) and pharmaceutically acceptable salt thereof in preparation of a human protein tyrosine phosphatase 1B inhibitor. Application in preparation of drugs for preventing and/or treating diabetes mellitus and related metabolic diseases thereof; the invention also relates to an application in preparation of drugs for preventing and/or treating hyperlipemia and related metabolic diseases. The dianthrone compound is extracted and separated from plants (including polygonum multiflorum), and can be used for preparing medicines for treating and preventing insulin resistance related metabolic diseases such as diabetes mellitus, hyperlipidemia and the like.

The invention belongs to the technical field of medicine and relates to a medical application of BBR (berberine). The BBR can be used for promoting mitochondrion autophagy and improving nerve cell functions. The BBR can promote mitochondrion autophagy of nerve cells, increase expression of mitochondrion autophagy related genes, timely remove damaged mitochondria and improve the quality of the mitochondria. The effects of the BBR on intracerebral mitochondrion autophagy of HD (huntington's disease) model animals are observed through two HD animal models (a mouse intraperitoneal injection 3-NP model and a rat corpus striatum injection malonic acid model). Research results indicate that the BBR can improve motion and cognition disorders of the HD model animals by promoting mitochondrion autophagy of the nerve cells.

The present invention relates to a new application of Chinese medicinal material schisandra berry and its extract as multidrug drug-resisting reversion agent, in particular, it can be matched with anti-tumor drug for curing tumor with multidrug drug-resistance, and can raise the sensitivity of tumor cell to anti-cancer drug and can raise the effect for resisting tumor.

The invention relates to applications of a histone deacetylase inhibitor in preparing an antishock drug, especially applications of S-(E)-3-[1-(1-benzo[d]oxazole-2-yl)-2-methylpropyl]-1H-1,2,3-triazole-4-yl]-N-Methylol acrylamide as shown in the specification in preparing the antishock drug, the shock is preferably selected from traumatic shock, hypovolemic shock, infectious shock, neurogenic shock, cardiogenic shock and anaphylactic shock, especially burning shock preferably.

The invention discloses application of 28 alkanol as an anti-Parkinson's disease substance in medicaments and health care products, in particular application in preparing medicaments and health care products for treating and preventing Parkinson's disease, complicating diseases and other related diseases. The invention also discloses a pharmaceutical composition for resisting the Parkinson's disease, which comprises the 28 alkanol and derivatives thereof and a pharmaceutically acceptable carrier. The pharmaceutical composition comprises tablets, capsules, pills, injection, sustained-release preparations, controlled release preparations and particulate delivery systems.

The present invention discloses one kind of flax root extract, and its preparation process, medicine composition and application in preparing medicine for preventing and treating hepatitis.

The invention relates to novel application of 2,4-dimethoxyl trans-stilben, in particular to novel application of 2,4-dimethoxyl trans-stilben for cutting fat and resisting senile dementia.