961 results about "Superoxide dismutase" patented technology

The invention is concerned with the solid product of roxburgh rose juice and the preparation method, it is: prepares the roxburgh rose juice or combined roxburgh rose juice to be granule, tablet, capsule or effervesce agent in order to improve the stability of vitamin C, vitamin p and superoxide dismutase in it, and reduce the nutritive value loss of roxburgh rose juice. The preparation method is: 1) prepares clear roxburgh rose juice; 2) prepares roxburgh rose condensing juice; 3) adds 1% -50% accessories into the clear roxburgh rose juice or roxburgh rose condensing juice; 4) gets grains by wet-process, or makes instant powder of roxburgh rose then gets grains by wet-process; 5) the above grains dry at the temperature of 30 centigrade - 70 centigrade in order to get the solid products.

The invention pertains to using double stranded ribonucleic acid molecules such as small interfering RNA (siRNA) molecules to target an SOD gene to interfere with gene expression and SOD protein production. Method are disclosed for inhibiting expression of a target protein in a subject with a neurological disorder by introducing a small interference ribonucleic acid (siRNA) molecule into the subject with the neurological disorder, such as amyotrophic lateral sclerosis (ALS).

The invention discloses a preparation method of a mushroom ferment beverage with effect of improving immunity, and belongs to the technical field of food beverages. According to the method disclosed by the invention, mushrooms and / or medicinal plants, fruit and ginseng are adopted as raw materials. The method comprises the following steps: slicing, chopping or crushing the raw materials; uniformly mixing the sliced, chopped or crushed raw materials so as to obtain a mixture; after adding sugar in the mixture, fermenting the mixture in ferment microorganisms; adding sugar when the sugar content is lowered; continuing fermentation so as to obtain the mushroom ferment beverage. According to the method disclosed by the invention, ferment bacteria can regulate intestinal flora and generate SOD (superoxide dismutase), so that the raw materials can be successfully fermented; the prepared ferment beverage contains protease, lipase, SOD, pectinase, lucid ganoderma, cauliflower fungus, pleurotus eryngii polysaccharide, rare ginsenoside, Rb2, C-K and the like. According to the method disclosed by the invention, the fermentation liquor and mycelium of the mushrooms can be directly used for fermentation; compared with sporophore, the raw materials are easier to obtain, and the method has the advantages of being short in fermentation cycle, easy in formula, simple in fermentation process, and the like.

The invention discloses a whitening cosmetic product, a preparation method and application thereof. The whitening cosmetic product comprises the components in percentage by mass: 0.00001to 0.001 percent of recombined human angiogenin, 0.00001 to 0.001 percent of metallothionein, 0.00001 to 0.001 percent of human epidermal growth factor, 0.00001to 0.001 percent of IL-1RA, 0.1 to 0.5 percent of superoxide dismutase, 0.1 to 0.5 percent of low molecular liquaemin, 1 to 5 percent of arbutin, 5 to 25 percent of stabilizer, 0.02 to 0.3 percent of hyaluronic acid, 0.5 to 5 percent of methylpropanediol, 0.5 to 3.5 percent of lactobacillus / mung bean fermentation liquid, 0.5 to 5 percent of dissolved protease, 0.5 to 8 percent of vitamin C sodium phosphate, 0.3 to 0.7 percent of 1,2-hexanediol or 1,2-capryl glycol, 1 percent to 5 percent of oat Beta-glucan, 1 to 5 percent of soy isoflavone and the balance of water. The whitening cosmetic product can be preserved for a long time, has no side effect on skin and is suitable for long term use.

The invention relates to a method for processing farm and sideline products, which is a method for processing black garlic through enzymatic reaction fermentation. The method comprises sectional and continuous enzymosis in a sealed container: firstly, performing the first section of the enzymosis in a temperature range from 85 to 95 DEG C for 30 to 50 hours; secondly, performing the second section of the enzymosis continuously in a temperature range from 65 to 75 DEG C for 60 to 110 hours; and thirdly, performing the third section of the enzymosis continuously in a temperature range from 55 to 65 DEG C for 60 to 110 hours to obtain a black garlic product. The method does not have a process for replenishing water in the process of the enzymosis so as to improve the flavor and the quality of the black garlic and shorten the processing time effectively; with the continuous and automatic enzymosis, the processing course is simpler; and the product retains the original effective components to the utmost extent, and the contents of SOD superoxide dismutase and polyphenols are higher than that of the garlic products produced by the prior techniques from Japan and Korea.

The invention relates to the field of stem cells, and discloses novel use of a stem cell exosome, and particularly discloses novel use of a human amniotic mesenchymal stem cell exosome. The experiment result shows that a human amniotic mesenchymal stem cell is capable of promoting growth of HDF cells, improving the activity of SOD (Superoxide Dismutase) enzyme in the cells, reducing attacks and damages to the cells caused by oxygen radicals generated by ultraviolet radiation induction, and reducing the death rate of the cells. The use shows that the human amniotic mesenchymal stem cell exosome has an anti-photoaging effect, and meanwhile, the human amniotic mesenchymal stem cell exosome is free of phototoxicity, so that application of the human amniotic mesenchymal stem cell exosome in preparation of an anti-ageing preparation is provided. The invention also provides an anti-ageing preparation of the human amniotic mesenchymal stem cell exosome.

The invention provides a feed for improving the disease resistance of a grass carp. The feed is characterized by comprising soybean cake, wheat meal, shell meal, fish meal, table salt, rice bran, fish oil, betaine, traditional Chinese medicine feed premix additive, zinc-containing polypeptide, zinc-containing microelement additive, vitamin mixture additive at least containing vitamin C, vitamin E and inositol, yeast and amino acid mixture additive at least containing threonine. The feed provided by the invention can improve the immunity of the organism of the grass carp and protect the grass carp from getting sick; the application of antibacterial chemical medicines and anti-virus chemical medicines is reduced to a certain degree, the survival rate of the grass carp is increased, and the activity of lysozyme and superoxide dismutase in the grass carp is improved; and moreover, the feed ensures little drug residue and low toxicity, and does not influence the quality of the grass carp or harm the human health.

The invention provides a special private care wet tissue for women. The private care wet tissue is produced through the following steps of: preparing a wet tissue stock solution from a nanosilver solution, water soluble vitamin E, hyaluronic acid, lauric acid modified superoxide dismutase, chamomile flower water, a hydrolyzed pearl solution, a saponin extract, 1,2-propylene glycol, isothiazolinone and deionized water at a certain ratio; evenly and dropwise adding the wet tissue stock solution on a nonwoven spunlace membrane; then hermetically packaging the nonwoven spunlace membrane. For use, the special private care wet tissue for women provided by the invention only needs to be put to flatly cover the private part of a woman, and after a short wait, the wet tissue is used for wiping the private part of the women back and forth a plurality of times. The private care wet tissue special for women provided by the invention is capable of sterilizing and disinfecting the private part of the woman, and also capable of moisturizing and cleaning the skin of the private part; the private care wet tissue has no any side effect and no any irritation.

The invention relates to a technology system applicable to identification and evaluation of cold resistance of isolated parts of different bamboo varieties, in particular to a method for identifying and evaluating the cold resistance of bamboos. The method for identifying and evaluating the cold resistance of the bamboos is characterized by comprising the following steps of: a) taking a twig of the same bamboo age and with a length of 30 centimeters as a reference; b) quick-freezing a part of processed leaves in liquid nitrogen for 30 minutes and then storing the leaves into a refrigerator at the temperature of 80 DEG C below zero and the like. The method for identifying and evaluating the cold resistance of the bamboos is characterized by: a) conductivity determination; b) determination of soluble sugar content; c) determination of soluble protein content; d) malondialdehyde (MDA) determination; e) praline determination; f) determination of activities of superoxide dismutase (SOD); and g) determination of activities of peroxidase (POD).

The invention discloses cordyceps mycelia and a preparation method thereof. The preparation method of the cordyceps mycelia comprises the following steps of inoculation and constant-temperature cultivation of paecilomyces hepialid, seeding tank cultivation, fermentation tank cultivation, ultralow-temperature vacuum concentration, freeze drying and crushing. In comparison with the cordyceps mycelia produced in the prior art, the cordyceps mycelia produced by the method has the advantages that the calcium content is increased by 90-120 times, the magnesium content is increased by 1-2 times, the contents of ferrum, zinc, cordycepic acid and cordycepin are increased by 20-50%, and the superoxide dismutase (SOD) activity is increased by 20-30%. Therefore, the health efficacy of the product is remarkably improved.

The invention relates to SOD cell repair liquid and a preparation method thereof. The repair liquid contains superoxide dismutase (SOD), aloe juice, hyaluronic acid solution, alpha-lipoic acid and vitamin E; the weight ratio of the aloe juice, the hyaluronic acid solution, the alpha-lipoic acid to the vitamin E is 200-650 : 100-750 : 0.03-0.1 : 0.5-4; every 100g of the repair liquid contains 40000-4000000 activity unit of SOD; the preparation method is as follows: taking cactus stems and carrying out cell disruption, ultrafilter concentration and multistage precipitation and centrifugal separation process on the cactus stems to obtain crude enzyme supernatant; carrying out three-stage purification process and vacuum drying and grinding on the crude enzyme supernatant to obtain SOD freeze-dried powder; taking aloe plant leaves and carrying out degradation, decoloration, centrifugal separation process and filtration on the aloe plant leaves to obtain the aloe juice; blending the raw materials (components) according to the weight ratio for preparation to obtain the SOD cell repair liquid. The invention has the function of oxidation resistance, can alleviate physical fatigue and strengthen immunity of human body.

A method for quantifying a neurodegenerative disorder in a patient that includes obtaining a fluid sample from the subject; measuring a protein biomarker complex in said fluid sample and correlating the measurement with mild cognitive impairment or Alzheimer's disease status. The biomarkers include those that comprise at least one of a transthyretin protein and / or a prostaglandin-H2 D-isomerase protein, and at least one second, different protein selected from a transthyretin, prostaglandin-H2 D-isomerase, beta-2-microglobulin, cystatin C, superoxide dismutase [Cu—Zn], plasma retinol-binding protein, phosphatidylethanolamine-binding protein, carbonic anhydrase 2, prostaglandin-H2 D-isomerase, and / or serotransferrin protein.

The invention relates to a method for preparing gold thread jujube enzyme from jujube paste of gold thread jujube, comprising the following steps of: making the jujube paste, carrying out primary enzymolysis and secondary enzymolysis, blending, sterilizing, fermenting, freezing, drying and finally obtaining the enzyme of the jujube paste of the gold thread jujube with the water content of being less than 5%. The gold thread jujube enzyme prepared by the method contains rich protease, lipase, superoxide dismutase, amylase, vitamins, minerals and secondary metabolites such as phenols, flavonoids and the like, and as a novel food and cosmetic additive in the market, the gold thread jujube enzyme has a very wide application prospect.

The invention discloses a preparation method of a pineapple and orange composite ferment beverage. The preparation method comprises the following steps of step I, separately taking raw materials of fresh pineapples and oranges, performing peeling, performing separate dicing and performing uniform mixing so as to obtain fruit raw materials; step II, taking fungus powder, and adding pure water for diluting so as to obtain fermentation fungus water; step III, adding the fungus water to the fruit raw materials until the level of the fungus water exceeds the surfaces of the fruit raw materials, then performing sealing, loading the fruit raw materials and the fungus water, which are sealed, in an incubator for fermentation, after fermentation, taking out the fermented fruit raw materials and the fermented fungus water, performing filtering so as to obtain a ferment stock solution, and placing the ferment stock solution in a refrigerator for after-ripening so as to obtain ferment liquid; step IV, adding honey, pure water and white granulated sugar to the obtained ferment liquid obtained in step III, performing uniform mixing, then adding vitamin C and beta-carotene, and performing homogenizing so as to obtain the pineapple and orange composite ferment beverage. The prepared composite ferment beverage is delicately fragrant in smell, fine and smooth in mouth feel, and moderate in sour and sweet degrees, and the activity of superoxide dismutase (SOD) contained in the composite ferment beverage achieves 100-150U / g.

The invention provides a novel enzyme, and preparation and use thereof. In terms of 217 kcal of calories, the total content of every 100g of the novel enzyme comprises 0.6g of fat, 1.31g of protein, 0.5g of minerals, 911mg of sodium, 31.2g of oligosaccharide, 2166u of superoxide dismutase, 856mg of vitamin B, 1276mg of vitamin C, 24g of soluble fibers, and 6.7g of insoluble fibers. After the novel enzyme is absorbed by a human body, the cells can be activated rapidly, and the red blood cells can be increased rapidly; meanwhile, the novel enzyme resists bad bacteria and viruses, has the anti-aging effect and can prevent functional aging.

The invention discloses a crease resistance and moisture retention liposome. The crease resistance and moisture retention liposome comprises, by mass, 1-3% of phosphatide, 0.5-1.5% of cholesterol, 0.05-0.15% of an antioxidant, 0.5-1.5% of Tween-80, 2-6% of a cryoprotectant, 84-94% of a phosphate buffering solution with the pH value of 6.5-7, 0.4-1.5% of an aqueous solution of superoxide dismutase, 0.4-1.5% of an aqueous solution of hyaluronic acid and 0.4-1.5% of an aqueous solution of ceramide, and the sum of the mass percentages of above components is 100%. The invention discloses a preparation method of the crease resistance and moisture retention liposome. The method comprises the following steps: preparing a blank liposome, wrapping active components by the blank liposome, and carrying out freeze-thawing and freeze-drying to prepare the crease resistance and moisture retention liposome. The crease resistance and moisture retention liposome can be added to cosmetics in order to prepare cosmetics with crease resistance and moisture retention efficacies.

The invention discloses a firming and repairing fair mask product which is prepared by soaking mask paper with the liquid prepared from the following raw materials in parts by weight: 0.1-3 parts of hyaluronic acid oligomer, 0.1-2.5 parts of hyaluronic acid, 0.7-30 parts of synthetic egg white powder, 1-7 parts of an aloe extract, 0.7-9 parts of propylene glycol, 5-50 parts of 1,2-butylene glycol, 5-30 parts of glycerol, 40-80 parts of a ginseng extract, 10-50 parts of a milkvetch root extract, 20-50 parts of a baical skullcap root extract, 20-80 parts of a small cucumber extract, 0.1-1 part of a licorice extract, 0.3-2 parts of arbutin, 1-10 parts of superoxide dismutase, 1-10 parts of a coenzyme q10, 0.1-5 parts of beta-glucan, and the balance of water which is added until the total amount is 1000 parts. The mask product can reduce skin injuries, repair damaged cells, delay skin wrinkling, relieve the generation of facial dark stains and replenish and lock water, and is antiallergic.

This invention provides modified biopolymers comprising biopolymers attached to at least one non-proteinaceous catalyst capable of dismutating superoxide in the biological system or precursor ligand thereof. The invention further provides pharmaceutical compositions comprising the modified biopolymer and therapeutic methods comprising administering the modified biopolymer to a subject in need thereof.

A method for quantifying a neurodegenerative disorder in a patient that includes obtaining a fluid sample from the subject; measuring a protein biomarker complex in said fluid sample and correlating the measurement with mild cognitive impairment or Alzheimer's disease status. The biomarkers include those that comprise at least one of a transthyretin protein and / or a prostaglandin-H2 D-isomerase protein, and at least one second, different protein selected from a transthyretin, prostaglandin-H2 D-isomerase, beta-2-microglobulin, cystatin C, superoxide dismutase [Cu—Zn], plasma retinol-binding protein, phosphatidylethanolamine-binding protein, carbonic anhydrase 2, prostaglandin-H2 D-isomerase, and / or serotransferrin protein;

The invention discloses cold process soap added with fig protoplasm, and the cold process soap is prepared by taking fresh fig protoplasm, oil, sodium hydroxide and distilled water as principal raw materials, adding essential oil as auxiliary raw materials according to requirements, and preparing at low temperature. According to the invention, protoplasm of squashy fresh figs is added into the formula, wherein the protoplasm is enriched in substances having the effects of repairing, anti-oxidizing and the like on human cells, such as polysaccharide substance, superoxide dismutase and anthocyanin, and nutritional components, such as vitamin and amino acid; the cold process soap disclosed by the invention is prepared at normal temperature, so that effective components and structures thereof of the substances cannot be destroyed; useful effects on human bodies of the cold process soap can be played better; the cold process soap disclosed by the invention does not contain chemical additive products harmful on the human bodies and is purely natural; the cold process soap not only has the effects of daily cleaning, caring skin and hairdressing but also has the health-care effect, and conforms to high-quality living requirements of modern people; and furthermore, the preparation method is simple and safe.

The present invention relates to a cosmetic or pharmaceutical composition to reduce skin damage caused by aging and / or the environment. The composition can include a genus Centipeda plant extract, a trace metal source in a skin absorbing form in an amount effective for activating or enhancing superoxide dismutase enzyme, and a carrier suitable for topical administration. The compound may alternatively include a genus Centipeda plant extract and a low molecular weight transporter and an ion-pair delivery system including a donating composition and an accepting composition, wherein the donating composition and the accepting composition are combined to form a bound ion-pair, and a carrier suitable for topical administration.

The invention provides topical compositions and methods for using the compositions. The compositions can be used for the treatment of fibrotic or connective tissue disorders involving scarring, sub-dermal plaque accumulations, or fibrosis of muscle tissue. The disorders can be painlessly treated by the topical application of a composition described herein. One or more calcium channel blocker agents can serve as an active ingredient of the compositions, optionally in combination with, for example, one or more of emu oil and superoxide dismutase. The composition can further include pharmaceutically acceptable carriers that can facilitate the non-invasive transdermal delivery of the active(s) to subdermal sites.

A composition and method for treatment and / or prophylaxis of stressed-induced conditions and a method of forming the composition are disclosed. The composition includes hyaluronic acid and superoxide dismutase configured to mitigate denaturing of the superoxide dismutase in a digestive track of an animal. Mitigating the denaturing of the superoxide dismutase allows simultaneous administration of both the hyaluronic acid and superoxide dismutase to the circulatory and lymph systems of an animal.

The invention provides a medical dressing, a preparation method of the medical dressing and the preparation method of a dressing plaster. The medical dressing comprises spirulina, spirulina extract and Chinese herbal medicines, wherein the spirulina extract comprises phycocyanin, chlorophyll, superoxide dismutase, polysaccharide, ions and vitamins. The dressing plaster comprises a base layer, a bonding layer, an absorbing layer and a treating layer which are stacked sequentially, wherein the treating layer contains the dressing. The dressing comprising the spirulina and the spirulina extract has the treatment functions of stopping bleeding, promoting wound healing, killing and inhibiting bacteria, relieving pain and the like, and can be used for preventing wound infection. The dressing plaster has the functions of the dressing and is easy to use.

The invention discloses a cicada extract shampoo and preparation thereof. The cicada extract shampoo disclosed by the invention includes 0.1 to 0.5% by weight of cicada extract. The cicada extract is added in the cicada extract shampoo disclosed by the invention, thus the utilization rate of the active components such as SOD (Superoxide Dismutase), amino acid, hyaluronic acid, N6-(2-hydroxyethyl ) adenosine and the like is greatly improved, the maintenance effect is well improved and the UV damage to the scalp and the hair is effectively reduced, the consumption of the cicadae is reduced, theproduction cost is reduced, and valuable cordyceps raw materials are saved, therefore, the cicada extract shampoo has important practical and commercial significance.

Provided are methods for diagnosing sporadic and familial forms of amyotrophic lateral sclerosis (“ALS”) that detect conformers or conformer patterns of the copper-zinc superoxide dismutase-1 (“SOD-1”) enzyme that are common to sporadic or familial ALS individuals but distinct from SOD-1 conformers of normal individuals. Methods of identifying candidate drugs that modulate SOD-1 conformer formation also are provided.

The invention discloses a blueberry SOD (Superoxide Dismutase) red wine and a preparation method thereof. The blueberry SOD red wine comprises 75ml of blueberry primary extraction solution, 100,000-200,000 units of blueberry SOD crude enzyme and 675ml of red wine. The preparation method of the blueberry SOD red wine comprises the following steps of: (1) cleaning blueberry; (2) draining water on the surface of the blueberry; (3) crushing and pulping by using a crushing and pulping machine, adding one time of volume of 4DEG C de-ionized water and carrying out ultrasound crushing at the constant temperature for 2 hours; (4) centrifuging to obtain supernate as the primary extraction solution; (5) intercepting the primary extraction solution to obtain a concentrated solution with the molecular weight of 20,000-60,000; (6) adding fucose as an SOD protecting agent and carrying out vacuum freezing and drying to obtain the blueberry SOD crude enzyme; and (7) mixing the blueberry SOD crude enzyme with the primary extraction solution, then adding the mixture into the red wine, sterilizing and bottling. The blueberry SOD wine obtained by the preparation method disclosed by the invention has the advantages of abundant nutrient components, favorable mouth feeling and high SOD survival rate.

Oxidative damage contributes to cone cell death in retinitis pigmentosa and death of rods, cones, and retinal pigmented epithelial (RPE) cells in ocular oxidative stress related diseases including age-related macular degeneration and retinitis pigmentosa. Oral antioxidants may provide modest benefits, but more efficient ways of preventing oxidative damage are needed. Compositions and methods are provided herein for the prevention, amelioration, and / or treatment of early or late stage ocular disease by increasing the expression or activity of one or more peroxidases in cells of the eye, particularly retinal cells, and further optionally increasing the expression or activity of one or more superoxide dismuatases in the same cells.

The invention discloses a preparation method of improving the content of active SOD (Superoxide Dismutase) in an enzyme. The method comprises the following steps: respectively preparing a cordycep fermenting bacterial liquid and a rainbow conk fermenting bacterial liquid; preparing an edible mushroom enzyme fermenting liquid of fruits and vegetables; sequentially and continuously fermenting the cordycep fermenting bacterial liquid and the rainbow conk fermenting bacterial liquid in the edible mushroom enzyme; mechanically breaking and extruding, and collecting the fermenting liquid. According to the preparation method provided by the invention, by combining actual production of the enzyme, two steps of fermentation by the cordyceps fermenting bacterial liquid and the rainbow conk fermenting bacterial liquid are added in the fermenting process, and cells are mechanically and forcibly crushed to facilitate overflow of the SOD from cells from inside to outside. According to the preparation method of the process provided by the invention, the content of the active SOD prepared by fermentation is improved.