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2 results about "Superoxide dismutase" patented technology
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Superoxide dismutase (SOD, EC 1.15.1.1) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O₂⁻) radical into either ordinary molecular oxygen (O₂) or hydrogen peroxide (H₂O₂). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. Hydrogen peroxide is also damaging and is degraded by other enzymes such as catalase. Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen. One exception is Lactobacillus plantarum and related lactobacilli, which use a different mechanism to prevent damage from reactive (O₂⁻).
A traditional Chinese medicine massage oil for treating pediatric muscular torticollis, a preparation method and application thereof
PendingCN122097526AMuscular disorderPharmaceutical delivery mechanismPicrorhiza scrophulariifloraMalonicdialdehyde
The application discloses a traditional Chinese medicine massage oil for treating pediatric muscular torticollis and a preparation method and application thereof. The traditional Chinese medicine massage oil is mainly prepared from the following raw materials in parts by weight: Amomum villosum 5-15 parts, Picrorhiza scrophulariiflora 2-8 parts, Syzygium aromaticum 2-8 parts, Pericarpium Citri Reticulatae Viride 2-8 parts and Sedi Herba 2-8 parts. Compared with the prior art, the application provides a brand-new traditional Chinese medicine massage oil, which is scientific in formula, novel in compatibility, simple in preparation method and convenient to use. Animal experiments prove that the traditional Chinese medicine massage oil can significantly improve creatine kinase (CK) activity in neck muscles and superoxide dismutase (SOD) content in serum, reduce malondialdehyde (MDA) content in serum and effectively repair muscle damage. Clinical results prove that the traditional Chinese medicine massage oil can effectively improve clinical symptoms of pediatric muscular torticollis, and is worthy of further promotion.
Owner:JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
Application of Qixuekang in preparation of medicine for treating renal fibrosis
PendingCN122075577Arestore kidney functionRestore reduced glutathione levelsUrinary disorderPlant ingredientsSuperoxide dismutasePharmacology
The invention provides application of Qixuekang in preparation of a medicine for treating renal fibrosis. Experimental research proves that the Qixuekang administration can remarkably recover the renal function of a mouse with renal fibrosis in senescence-accompanied chronic kidney diseases, reduce the mouse kidney mesenchymal fibrosis level and the levels of fibrosis markers alpha-SMA and Col1, recover the content of reductive glutathione in the mouse, improve the activity of superoxide dismutase and improve the curative effect of the kidney fibrosis in the senescence-accompanied chronic kidney diseases. Therefore, kidney fibrosis phenotypes and fibrosis-related biochemical indexes of mice are improved. Qi-blood Kang can remarkably restore kidney mesenchymal transformation related gene and protein expression, and kidney fibrosis phenotypes in chronic kidney diseases are improved by reducing related inflammatory media; qiwankang can significantly improve mitochondrial membrane potential, increase mitochondrial neogenesis related gene expression and reduce generation of active oxygen.
Owner:YUNNAN BAIYAO GRP CO LTD