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11 results about "Superoxide dismutase" patented technology

Superoxide dismutase (SOD, EC 1.15.1.1) is an enzyme that alternately catalyzes the dismutation (or partitioning) of the superoxide (O₂⁻) radical into either ordinary molecular oxygen (O₂) or hydrogen peroxide (H₂O₂). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. Hydrogen peroxide is also damaging and is degraded by other enzymes such as catalase. Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen. One exception is Lactobacillus plantarum and related lactobacilli, which use a different mechanism to prevent damage from reactive (O₂⁻).

Skin grafting material and use method thereof

PendingCN119488636Aavoid damagepromote wound healingProsthesisCollagen spongeSuperoxide dismutase
The invention relates to a skin grafting material and a using method thereof. The skin grafting material is composed of compressed sponge and repairing liquid. The compressed sponge is selected from chitosan sponge, collagen sponge or polyvinyl formal sponge; the repairing liquid is selected from normal saline containing human epidermal growth factors and / or normal saline containing superoxide dismutase. The use method comprises the following steps: attaching the skin layer of the cut skin graft to the compressed sponge, then putting the compressed sponge into a medical skin rolling machine, and cutting the skin graft into micro skin graft; the cut miniature skin graft is soaked in the repairing liquid, is attached to the position to be subjected to skin grafting after fully absorbing the liquid and expanding, and is wrapped with gauze. The skin grafting material provided by the invention can reduce damage to newborn granulation when the skin grafting material is removed, has an antibacterial effect and improves scar hyperplasia contracture after a skin grafting wound operation; meanwhile, the sponge which absorbs the liquid and expands can slowly release the repairing liquid, so that skin cell regeneration is promoted, epithelization of a skin grafting area is accelerated, and wound healing is promoted; the healing effect is good, and the application prospect is wide.
Owner:HEBEI AINENG BIOTECH CO LTD

Whitening composition, whitening essence and preparation method thereof

The invention provides a whitening composition, whitening essence and a preparation method thereof, the whitening composition is prepared from the following raw materials in parts by weight: 10 to 15 parts of extract compound, 3 to 5 parts of compound polysaccharide, 2 to 4 parts of galactose yeast-like bacterium fermentation product filtrate, 1 to 3 parts of rhodopseudomonas palustris liquid, 0.1 to 0.3 part of soluble collagen and 0.5 to 1 part of superoxide dismutase; the extract compound is prepared from the following raw materials in parts by weight: 5 to 7 parts of radix cynanchi atrati extract, 3 to 5 parts of vitex agnus linteus extract, 1 to 3 parts of mussel extract, 2 to 4 parts of wild soybean seed extract and 1 to 3 parts of chamomilla recutita flower extract. The components of the whitening composition are reasonably compounded, the whitening composition is mild and non-irritant, synergistic interaction is achieved, rapid first-aid whitening can be achieved, 15-min first-aid whitening can be achieved, the skin can be restored to be bright and white, and the freckle removing and whitening effects can be comprehensively achieved by damaging melanocytes, inhibiting melanin generation and promoting melanin degradation. Meanwhile, the repairing, moisturizing and soothing effects are considered, no irritation is caused, and the safety is high.
Owner:CHAYAN BIOTECHNOLOGY CO LTD

A traditional Chinese medicine massage oil for treating pediatric muscular torticollis, a preparation method and application thereof

PendingCN122097526AMuscular disorderPharmaceutical delivery mechanismPicrorhiza scrophulariifloraMalonicdialdehyde
The application discloses a traditional Chinese medicine massage oil for treating pediatric muscular torticollis and a preparation method and application thereof. The traditional Chinese medicine massage oil is mainly prepared from the following raw materials in parts by weight: Amomum villosum 5-15 parts, Picrorhiza scrophulariiflora 2-8 parts, Syzygium aromaticum 2-8 parts, Pericarpium Citri Reticulatae Viride 2-8 parts and Sedi Herba 2-8 parts. Compared with the prior art, the application provides a brand-new traditional Chinese medicine massage oil, which is scientific in formula, novel in compatibility, simple in preparation method and convenient to use. Animal experiments prove that the traditional Chinese medicine massage oil can significantly improve creatine kinase (CK) activity in neck muscles and superoxide dismutase (SOD) content in serum, reduce malondialdehyde (MDA) content in serum and effectively repair muscle damage. Clinical results prove that the traditional Chinese medicine massage oil can effectively improve clinical symptoms of pediatric muscular torticollis, and is worthy of further promotion.
Owner:JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE

Traditional Chinese medicine for treating premature ejaculation

The invention relates to the field of health care products, and discloses a traditional Chinese medicine for treating premature ejaculation, which comprises cynomorium songaricum, cistanche, fructus psoraleae, morinda officinalis, illicium verum, oyster peptide, fossil fragments, cornu cervi degelatinatum, Chinese yam, rhizoma anemarrhenae, radix achyranthis bidentatae, lotus seed, actinolite, deer blood, ginseng, maca and superoxide dismutase in a ratio of 2: 2: 2: 2: 2: 1: 1: 1: 1: 1: 2: 1: 1: 1: 2: 1: 2: 1: 1: 1: 1. The traditional Chinese medicine for premature ejaculation provided by the invention contains various components such as cynomorium songaricum, morinda officinalis, oyster peptide, ginseng and the like, has various effects of warming yang and tonifying kidney, warming kidney and strengthening yang, enriching yin and nourishing kidney, securing essence and stopping enuresis, enhancing physical strength, improving sexual desire and the like, and has no toxic or side effect due to mutual neutralization and yin-yang regulation of the herbal medicine components.
Owner:GUANGDONG BAWEN PHARM CO LTD

Rosa roxburghii tratt fruit composite beverage with blood fat reducing function as well as preparation method and application thereof

The invention discloses a rosa roxburghii tratt composite beverage with a blood fat reducing function as well as a preparation method and application thereof, and belongs to the technical field of beverages and beverage processing. The rosa roxburghii tratt fruit juice beverage comprises the following components in parts by weight: 20-40 parts of rosa roxburghii tratt fruit microfiltration juice, 15-25 parts of apple juice, 10-20 parts of snow pear juice, 5-10 parts of lemon juice, 10-20 parts of litchi juice and 3-12 parts of natural honey. The rosa roxburghii tratt composite beverage contains the rosa roxburghii tratt microfiltration juice, the raw material of the rosa roxburghii tratt microfiltration juice is rosa roxburghii tratt, and the rosa roxburghii tratt is rich in various active ingredients such as vitamin C, superoxide dismutase, polyphenol, flavone, dietary fiber and the like, and has remarkable effects of reducing blood fat, resisting oxidation and regulating immunity; therefore, the rosa roxburghii tratt fruit microfiltration juice contained in the rosa roxburghii tratt fruit composite beverage in the embodiment can provide various active ingredients such as vitamin C, superoxide dismutase, polyphenol, flavone and dietary fibers for a drinker, the blood fat of the drinker can be reduced, and nutrition complementation and taste optimization can be achieved.
Owner:GUIZHOU SANLIWANG FOOD PROCESSING CO LTD

Antibacterial gel for skin mucosa based on traditional Chinese medicine component and hyaluronic acid composition

The invention discloses antibacterial gel for skin mucosa based on a traditional Chinese medicine component and hyaluronic acid composition and a preparation method. The formula consists of the following raw materials: saffron crocus extract, centella asiatica extract, vetiver extract, motherwort extract, cynanchum atratum extract, ligusticum sinensis extract, spirulina platensis extract, peony extract, lysostaphin, rice germ fermented oil, superoxide dismutase, hyaluronic acid and peony peptide. And lactoferrin. By adding the fructus cnidii extract, the skin mucosa antibacterial gel prepared by the invention can change the vagina environment on the basis of bacteriostasis, so that the probability of inflammation recurrence can be reduced, and meanwhile, skin wound repair can be realized on the basis of hyaluronic acid; meanwhile, the skin wound repairing capacity can be further improved through fibronectin.
Owner:素趣(浙江)生物科技有限责任公司

Preparation method of chlamydomonas reinhardtii polysaccharide granules

The invention discloses a preparation method of chlamydomonas reinhardtii polysaccharide granules, which comprises the following steps: extracting chlamydomonas reinhardtii polysaccharide to prepare polysaccharide dry powder, and mixing the polysaccharide dry powder with starch and magnesium stearate to prepare the chlamydomonas reinhardtii polysaccharide granules; the chlamydomonas reinhardtii polysaccharide is extracted by adopting a compound enzyme; the compound enzyme is prepared from cellulase, pectinase and superoxide dismutase according to the mass ratio of (1.8 to 2.2) to 1 to (0.8 to 1.2). According to the preparation method of the chlamydomonas reinhardtii polysaccharide granules, chlamydomonas reinhardtii polysaccharide is extracted to prepare polysaccharide dry powder, and the polysaccharide dry powder is mixed with starch and magnesium stearate to prepare the chlamydomonas reinhardtii polysaccharide granules; the compound enzyme is adopted for enzymolysis, so that the cell wall structure of the chlamydomonas reinhardtii can be destroyed to promote the polysaccharide to be easily dissolved out, the problems of low extraction efficiency and low purity in the chlamydomonas reinhardtii polysaccharide extraction process are solved, the loss of the polysaccharide is also avoided to the greatest extent, and the obtained polysaccharide particles are high in antioxidant activity and good in water solubility.
Owner:JIANGSU ZHONGYOUXIN TECH CO LTD

Rosa roxburghii cold fermentation method

The invention discloses a roxburgh rose cold fermentation method which comprises the steps of raw material treatment, raw material stacking, low-temperature fermentation, squeezing separation, filtering and filling and the like, roxburgh rose pulp is used as a main raw material and supplemented with hawthorn for mixed fermentation, a low-temperature long-time fermentation process is adopted through a compounded strain, low-temperature fermentation is beneficial to improving the taste and fragrance, and the taste of the roxburgh rose is improved; in addition, the low-temperature fermentation can also reduce the generation of harmful metabolites, such as diacetyl, higher alcohols and the like. According to the method, the nutritional ingredients of the roxburgh rose can be extracted and reserved to the maximum extent, the method is convenient and easy to implement and suitable for large-scale production, and the final product is high in vitamin and superoxide dismutase content, easy to digest and absorb, unique in flavor and softer in taste.
Owner:GUIZHOU GOLDEN CAN PHARMACEUTICAL BIOTECHNOLOGY CO LTD

Application of Qixuekang in preparation of medicine for treating renal fibrosis

PendingCN122075577Arestore kidney functionRestore reduced glutathione levelsUrinary disorderPlant ingredientsSuperoxide dismutasePharmacology
The invention provides application of Qixuekang in preparation of a medicine for treating renal fibrosis. Experimental research proves that the Qixuekang administration can remarkably recover the renal function of a mouse with renal fibrosis in senescence-accompanied chronic kidney diseases, reduce the mouse kidney mesenchymal fibrosis level and the levels of fibrosis markers alpha-SMA and Col1, recover the content of reductive glutathione in the mouse, improve the activity of superoxide dismutase and improve the curative effect of the kidney fibrosis in the senescence-accompanied chronic kidney diseases. Therefore, kidney fibrosis phenotypes and fibrosis-related biochemical indexes of mice are improved. Qi-blood Kang can remarkably restore kidney mesenchymal transformation related gene and protein expression, and kidney fibrosis phenotypes in chronic kidney diseases are improved by reducing related inflammatory media; qiwankang can significantly improve mitochondrial membrane potential, increase mitochondrial neogenesis related gene expression and reduce generation of active oxygen.
Owner:YUNNAN BAIYAO GRP CO LTD

Oral pharmaceutical composition containing oseltamivir phosphate and application

The invention provides an oral pharmaceutical composition containing oseltamivir phosphate and application of the oral pharmaceutical composition. The oral pharmaceutical composition is prepared from the following components in parts by weight: 20 to 40 parts of oseltamivir phosphate, 8 to 10 parts of superoxide dismutase, 3 to 5 parts of quercetin and 0.8 to 1.2 parts of tetrahydromethylpyrimidine carboxylic acid. The oral quick-release film agent prepared from the oral pharmaceutical composition containing oseltamivir phosphate can be used for resisting influenza viruses, and the oral quick-release film agent prepared by the invention can be quickly dissolved out, avoids the liver first-pass effect, improves the bioavailability, achieves higher local drug concentration, quickly relieves symptoms, enhances the anti-influenza virus drug effect, is good in palatability, and can be used for preparing the oral quick-release film agent for resisting influenza viruses. The medicine is convenient for patients to take, improves compliance and reduces side effects.
Owner:HAINAN BRIGHT FUTURE PHARMA

Nickel-doped carbon nano enzyme as well as preparation method and application thereof

The invention relates to the technical field of carbon nano-enzymes, in particular to a nickel-doped carbon nano-enzyme as well as a preparation method and application thereof. Conventional metal-doped carbon nano-enzyme has POD activity and is not beneficial to later-stage healing of bacterial infected wounds. In order to solve the problems, the invention provides the nickel-doped carbon nano-enzyme which has no POD (peroxidase) activity, CAT (catalase) activity and SOD (superoxide dismutase) activity. The nickel-doped carbon nano enzyme is specifically a product obtained by a hydrothermal reaction of soluble nickel salt and cysteine under an alkaline condition, and metal nickel ions and amino groups in cysteine form coordination chemical bonds under a hydrothermal condition. The obtained nickel-doped carbon nano-enzyme is used for sterilizing by utilizing the photothermal effect, CAT activity and SOD activity of the nickel-doped carbon nano-enzyme, the nickel-doped carbon nano-enzyme can achieve the sterilizing effect, ROS cannot be continuously generated in the sterilizing process, and later-stage healing of bacterial infection wounds is more facilitated.
Owner:CHANGZHOU UNIV