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Medical skin care agent and preparation method thereof

A skin care and gel technology, which is applied in the field of medical skin care agents with antibacterial and anti-inflammatory properties and skin barrier repair and preparation thereof, can solve the problems of inability to repair skin barriers and wounds, high preparation cost, and achieve broad-spectrum antibacterial, The effect of repairing skin barrier and enhancing lipoid structure

Inactive Publication Date: 2012-08-08
佛山拜澳生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In view of the above deficiencies in the prior art, the purpose of the present invention is to provide a medical skin care agent and its preparation method, aiming to solve the problem that the existing medical skin care agent cannot repair the skin barrier and wound or the preparation cost is high

Method used

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  • Medical skin care agent and preparation method thereof
  • Medical skin care agent and preparation method thereof

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preparation example Construction

[0112] The present invention also provides the preparation method of described medical skin care agent, specifically comprises the following steps:

[0113] Step 1: disperse and swell the acrylate crosslinked copolymer in water;

[0114] Step 2: dissolving chitosan and chitosan derivative components in water in advance;

[0115] Step 3: Take an appropriate amount of gelling agent and mix it with the swelled acrylate cross-linked copolymer, and stir evenly; add a pH regulator to adjust the pH value to PH6.5~7.0;

[0116] Step 4: Add the dissolved chitosan and chitosan derivative components and the remaining gelling agent, and stir evenly at a slow speed;

[0117] Step 5: Add the preservative and stir well.

[0118] The medical skin care agent of the present invention, wherein the chitosan and chitosan derivative components have broad-spectrum antibacterial properties, can be used for the common symptoms of redness, swelling, peeling, itching and dermatitis of dry, damaged and...

Embodiment 1

[0120] Composition of medical skin care agent:

[0121] Phytoceramide 0.1%, hydrogenated lecithin 1.5%, cholesteryl stearate 0.3%, carboxymethyl chitosan 0.9%, triethanolamine 0.5%, diphenoxyethanol (liquipar PE) 0.06%, C10-30 Alkyl acrylate cross-linked copolymer 1%, distilled water balance.

[0122] making process:

[0123] Step 1: disperse and swell the acrylate crosslinked copolymer in water;

[0124] Step 2: dissolving chitosan and chitosan derivative components in water in advance;

[0125] Step 3: Take a small amount of gelling agent and mix it with the swollen acrylate cross-linked copolymer, and stir evenly; add a pH regulator to adjust the pH value to PH6.5~7.0;

[0126] Step 4: Add the dissolved chitosan and chitosan derivative components and the remaining gelling agent, and stir evenly at a slow speed;

[0127] Step 5: Add the preservative and stir well.

[0128] According to the GB / T 16886.5 Biological Evaluation of Medical Devices-In vitro Cytotoxicity Test ...

Embodiment 2

[0132] Composition of medical skin care agent:

[0133] Ceramide 1%, hydrogenated lecithin 0.5%, cholesteryl stearate 0.4%, carboxymethyl chitosan 3%, triethanolamine 1%, diphenoxyethanol (liquipar PE) 0.7%, C10-30 alkanes Acrylate cross-linked copolymer 0.5%, the rest in distilled water.

[0134] Preparation process: with embodiment 1.

[0135] According to GB / T 16886.5 Biological Evaluation of Medical Devices-in Vitro Cytotoxicity Test Standard, the cytotoxicity of the skin care agent in Example 2 was tested. The test for detecting cytotoxicity is the agar diffusion test, and the test result is that the cytotoxic reaction is not greater than grade 1 (cytotoxicity is divided into grades 0-4, grade 0 is no cytotoxicity, grade 1 is slight cytotoxicity, grade 2 is moderate cytotoxicity) Toxicity, grade 4 is moderate cytotoxicity).

[0136] According to GB / T 16886.10 Biological Evaluation of Medical Devices-Irritation and Delayed Type Hypersensitivity Test, the skin irritation...

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Abstract

The invention discloses a medical skin care agent and a preparation method thereof, wherein, the medical skin care agent provided in the invention mainly comprises chitosan or derivatives thereof, a gelling agent and preservative. Specifically, the gelling agent is advantaged in that: ceramide, a mixture of sphingolipids and phospholipids, ceramide analogue and the like are used to form a layered-structure gel phase structure which is similar to skin lipoid structure and capable of enhancing the lipoid structure of the skin itself, thereby realizing the function of repairing skin barrier; due to the adding of the chitosan or the derivatives thereof in the medical skin care agent, the medical skin care agent is provided with broad-spectrum anti-microbial property and can effectively repair common skin inflammation of redness, swelling, peeling, itching and the like for dry, damaged and sensitive skin, thereby realizing anti-microbial function and anti-inflammation function in medical skin care.

Description

technical field [0001] The invention relates to the field of medical skin care agents, in particular to a medical skin care agent with antibacterial, anti-inflammatory and skin barrier repairing properties and a preparation method thereof. Background technique [0002] In the prior art, many compositions or agents used for skin care have the function of repairing the skin barrier, and the raw materials used generally adopt sugar alcohols, calcium ions, grape sap, alkanediols, Chinese herbal medicine extracts, probiotics, etc. microbes, etc. However, the above compositions have no antibacterial and anti-inflammatory functions, and can only be used in ordinary cosmetics. Therefore, they cannot repair common redness, swelling, peeling, itching and other dermatitis symptoms of dry, damaged, sensitive skin, and are not suitable for antibacterial skin care. Anti-inflammatory effect. [0003] The document of patent number: 200580014813.5 discloses the use of the total extract of ...

Claims

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Application Information

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IPC IPC(8): A61K8/68A61K8/73A61K8/81A61K8/92A61Q19/00
Inventor 黄庆
Owner 佛山拜澳生物科技有限公司
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